Home Amines 13636-18-5
13636-18-5,MFCD00079301
Catalog No.:AA0011QB

13636-18-5 | Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-, hydrochloride (1:1)

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1g
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≥95%
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0011QB
Chemical Name:
Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-, hydrochloride (1:1)
CAS Number:
13636-18-5
Molecular Formula:
C23H26ClN
Molecular Weight:
351.9122
MDL Number:
MFCD00079301
SMILES:
CC(c1ccccc1)NCCC(c1ccccc1)c1ccccc1.Cl
NSC Number:
757826
Properties
Computed Properties
 
Complexity:
303  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:UNIVERSITYSYSTEMOFOHIO-US2008/33048,2008,A1Locationinpatent:Page/Pagecolumn2

Literature

Title: Real-time 2D separation by LC × differential ion mobility hyphenated to mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20120301

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Fendiline-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in human oral cancer cells.

Journal: Human & experimental toxicology 20090101

Title: Interaction of antagonists with calmodulin: insights from molecular dynamics simulations.

Journal: Journal of medicinal chemistry 20080612

Title: [Role of apoptosis in the kidney after reperfusion].

Journal: Orvosi hetilap 20080217

Title: 2'-hydroxy-fendiline analogues as potent relaxers of isolated arteries.

Journal: European journal of pharmacology 20070430

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods.

Journal: Journal of molecular graphics & modelling 20060301

Title: Spectrofluorimetric determination of fendiline in tablets.

Journal: Die Pharmazie 20051001

Title: 3-Chloro,4-methoxyfendiline is a potent GABA(B) receptor potentiator in rat neocortical slices.

Journal: European journal of pharmacology 20050110

Title: Calcium sensing receptors as integrators of multiple metabolic signals.

Journal: Cell calcium 20040301

Title: Calcimimetic and calcilytic drugs: just for parathyroid cells?

Journal: Cell calcium 20040301

Title: Arylalkylamines are a novel class of positive allosteric modulators at GABA(B) receptors in rat neocortex.

Journal: European journal of pharmacology 20020906

Title: The anti-anginal drug fendiline elevates cytosolic Ca(2+) in rabbit corneal epithelial cells.

Journal: Life sciences 20020719

Title: Fendiline mobilizes intracellular Ca2+ in Chang liver cells.

Journal: Clinical and experimental pharmacology & physiology 20010901

Title: Fendiline, an anti-anginal drug, increases intracellular Ca2+ in PC3 human prostate cancer cells.

Journal: Cancer chemotherapy and pharmacology 20010701

Title: Effects of the antianginal drug fendiline on Ca2+ movement in hepatoma cells.

Journal: Human & experimental toxicology 20010701

Title: Determination of fendiline and gallopamil by capillary isotachophoresis.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010615

Title: Dual effect of the antianginal drug fendiline on bladder female transitional carcinoma cells: mobilization of intracellular CA2+ and induction of cell death.

Journal: Pharmacology 20010501

Title: Fendiline-Induced Ca2+ movement in A10 smooth muscle cells.

Journal: The Chinese journal of physiology 20010331

Title: The anti-anginal drug fendiline increases intracellular Ca(2+) levels in MG63 human osteosarcoma cells.

Journal: Toxicology letters 20010308

Title: A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies.

Journal: Journal of molecular biology 20000331

Title: Crystallization and preliminary diffraction analysis of Ca(2+)-calmodulin-drug and apocalmodulin-drug complexes.

Journal: Proteins 19970501

Title: [The relationship between anticonvulsant and anti-anxiety effects of calcium channel blockers].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 19970101

Title: Inhibitors of calmodulin impair the constitutive but not the inducible nitric oxide synthase activity in the rat aorta.

Journal: The Journal of pharmacology and experimental therapeutics 19920501

Title: Effects of the calmodulin antagonists fendiline and calmidazolium on aggregation, secretion of ATP, and internal calcium in washed human platelets.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19910101

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Tags:13636-18-5 Molecular Formula|13636-18-5 MDL|13636-18-5 SMILES|13636-18-5 Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-, hydrochloride (1:1)