Home Other Building Blocks 122063-01-8
122063-01-8,MFCD00143686
Catalog No.:AA0016MH

122063-01-8 | [bAla8]-Neurokinin A(4-10)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$209.00   $147.00
- +
5mg
98%
1 week  
$527.00   $369.00
- +
10mg
98%
1 week  
$812.00   $569.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0016MH
Chemical Name:
[bAla8]-Neurokinin A(4-10)
CAS Number:
122063-01-8
Molecular Formula:
C35H56N8O10S
Molecular Weight:
780.9317
MDL Number:
MFCD00143686
SMILES:
CSCC[C@@H](C(=O)N)NC(=O)[C@@H](NC(=O)CCNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)N)CO)CC(C)C
Properties
Computed Properties
 
Complexity:
1280  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
54  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
10  
Rotatable Bond Count:
25  
XLogP3:
-3.1  

Literature

Title: Melatonin inhibits tachykinin NK₂ receptor-triggered 5-HT release from guinea pig isolated colonic mucosa.

Journal: British journal of pharmacology 20110301

Title: Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation.

Journal: American journal of physiology. Lung cellular and molecular physiology 20081201

Title: Neurokinin 2 receptor-mediated activation of protein kinase C modulates capsaicin responses in DRG neurons from adult rats.

Journal: The European journal of neuroscience 20080601

Title: Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080301

Title: Effect of melatonin on the vasopressin secretion as influenced by tachykinin NK-1 receptor agonist and antagonist: in vivo and in vitro studies.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201

Title: Role for NK(1) and NK(2) receptors in the motor activity in mouse colon.

Journal: European journal of pharmacology 20070910

Title: Neurokinins enhance excitability in capsaicin-responsive DRG neurons.

Journal: Experimental neurology 20070501

Title: MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist.

Journal: European journal of pharmacology 20061107

Title: The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation.

Journal: British journal of pharmacology 20050701

Title: Impaired capsaicin and neurokinin-evoked colonic motility in inflammatory bowel disease.

Journal: Journal of gastroenterology and hepatology 20050501

Title: Action of tachykinins in the rat hippocampus: modulation of inhibitory synaptic transmission.

Journal: The European journal of neuroscience 20030601

Title: Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.

Journal: Pharmacology 20020501

Title: Tachykinin NK(2) receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study.

Journal: British journal of pharmacology 20010801

Title: Tachykinin activation of human monocytes from patients with rheumatoid arthritis: in vitro and ex-vivo effects of cyclosporin A.

Journal: Neuropeptides 20010401

Title: Tachykinins contribute to nerve-mediated contractions in the human esophagus.

Journal: Gastroenterology 20010101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:122063-01-8 Molecular Formula|122063-01-8 MDL|122063-01-8 SMILES|122063-01-8 [bAla8]-Neurokinin A(4-10)