Name: Name:Leucomycin
Brand: AABLOCKS
SKU: AA001AEU
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA001AEU

Chemical Name: Leucomycin

CAS Number: 1392-21-8

Molecular Formula: C35H59NO13

Molecular Weight: 701.8419

MDL Number: MFCD00210322

SMILES: O=CCC1CC(C)C(O)C=CC=CCC(OC(=O)CC(C(C1OC1OC(C)C(C(C1O)N(C)C)OC1OC(C)C(C(C1)(C)O)O)OC)O)C

Properties

Complexity: 1110

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 16

Defined Bond Stereocenter Count: 2

Heavy Atom Count: 49

Hydrogen Bond Acceptor Count: 14

Hydrogen Bond Donor Count: 5

Rotatable Bond Count: 8

XLogP3: 0.5

Literature fold

Title: Isolation and characterization of 23-O-mycinosyl-20-dihydro-rosamicin: a new rosamicin analogue derived from engineered Micromonospora rosaria.

Journal: The Journal of antibiotics20100601

Title: Novel azalides derived from 16-membered macrolides. Part II: Isolation of the linear 9-formylcarboxylic acid and its sequential macrocyclization with an amino alcohol or an azidoamine.

Journal: Bioorganic & medicinal chemistry20081201

Title: Design and synthesis of novel leucomycin analogues modified at the C-3 position. Part II: 3-O-(3-Aryl-2-propenyl)leucomycin analogues.

Journal: Bioorganic & medicinal chemistry20080415

Title: Novel azalides derived from sixteen-membered macrolides.

Journal: The Journal of antibiotics20070701

Title: Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD).

Journal: Journal of pharmaceutical and biomedical analysis20070411

Title: [Identification of the components and products of hydrolysis in acetylleucomycin by LC-MS].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20060501

Title: Sesquiterpenes and flavonoid aglycones from a Hungarian taxon of the Achillea millefolium group.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20020101

Title: Screening for new compounds with antiherpes activity.

Journal: Antiviral research19841001

Title: In vitro and in vivo susceptibility of atypical mycobacteria to various drugs.

Journal: Reviews of infectious diseases19810101

Title: PACHTMAN EA, et al. Leucomycin; a new antibiotic. Am J Pharm Sci Support Public Health. 1958 Oct;130(10):342-4.

Title: Vézina C, et al. Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother. 1979 May;15(5):738-46.

Title: La T, et al. Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs. Aust Vet J. 2019 Sep 17.

Title: Hassan AB, et al. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. Dtsch Tierarztl Wochenschr. 1990 Aug;97(8):315-7.

1392-21-8 | Leucomycin