14611-52-0,MFCD00069299
Catalog No.:AA001DMJ

14611-52-0 | Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, hydrochloride (1:1), (αR)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
≥98%
in stock  
$46.00   $32.00
- +
250mg
≥98%
in stock  
$86.00   $60.00
- +
500mg
≥98%
in stock  
$133.00   $93.00
- +
1g
≥98%
in stock  
$199.00   $139.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001DMJ
Chemical Name:
Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, hydrochloride (1:1), (αR)-
CAS Number:
14611-52-0
Molecular Formula:
C13H18ClN
Molecular Weight:
223.7417
MDL Number:
MFCD00069299
SMILES:
C[C@@H](N(CC#C)C)Cc1ccccc1.Cl
Properties
Computed Properties
 
Complexity:
195  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  

Literature

Title: Inhibition of monoamine oxidase-B by selegiline reduces cigarette smoke-induced oxidative stress and inflammation in airway epithelial cells.

Journal: Toxicology letters 20170215

Title: Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction.

Journal: Chemico-biological interactions 20150325

Title: Deuterium-substituted L-DOPA displays increased behavioral potency and dopamine output in an animal model of Parkinson's disease: comparison with the effects produced by L-DOPA and an MAO-B inhibitor.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20150201

Title: Deprenyl enhances the teratogenicity of hydroxyurea in organogenesis stage mouse embryos.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130801

Title: Comparison of the cutaneous iontophoretic delivery of rasagiline and selegiline across porcine and human skin in vitro.

Journal: International journal of pharmaceutics 20121115

Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuroblastic apoptosis in the subventricular zone is caused by 1-methy-4-phenylpiridinium (MPP(+)) converted from MPTP through MAO-B.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20121101

Title: Retention rate of selegiline in early Parkinson's disease: a retrospective survey.

Journal: International journal of clinical practice 20121001

Title: Involvement of monoamine oxidase B on models of postoperative and neuropathic pain in mice.

Journal: European journal of pharmacology 20120905

Title: Cerebral blood flow and freezing of gait in Parkinson's disease.

Journal: Acta neurologica Scandinavica 20120901

Title: Pramipexole-related chronic lower limb oedema in a patient with Parkinson's disease.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120901

Title: Modulations of brain amines and dopaminergic behavior by a novel, reversible and selective MAO-B inhibitor.

Journal: Brain research 20120827

Title: Disease progress and response to treatment as predictors of survival, disability, cognitive impairment and depression in Parkinson's disease.

Journal: British journal of clinical pharmacology 20120801

Title: Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors.

Journal: Angewandte Chemie (International ed. in English) 20120709

Title: AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH.

Journal: Biochemical and biophysical research communications 20120622

Title: Subthalamic deep brain stimulation at individualized frequencies for Parkinson disease.

Journal: Neurology 20120612

Title: Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation.

Journal: Biochemistry. Biokhimiia 20120601

Title: Cardiovascular baroreceptor activity and selective inhibition of monoamine oxidase.

Journal: European journal of pharmacology 20120515

Title: Basic cell physiological activities (cell adhesion, chemotaxis and proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120501

Title: Safety of selegiline transdermal system in clinical practice: analysis of adverse events from postmarketing exposures.

Journal: The Journal of clinical psychiatry 20120501

Title: Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120401

Title: In vitro-in vivo correlation for intrinsic clearance for CP-409,092 and sumatriptan: a case study to predict the in vivo clearance for compounds metabolized by monoamine oxidase.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120401

Title: In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand.

Journal: Synapse (New York, N.Y.) 20120401

Title: 8-Substituted 3-arylcoumarins as potent and selective MAO-B inhibitors: synthesis, pharmacological evaluation, and docking studies.

Journal: ChemMedChem 20120305

Title: Selegiline transdermal system (STS) as an aid for smoking cessation.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120301

Title: Induction of adipose-derived stem cell into motoneuron-like cells using selegiline as preinducer.

Journal: Brain research 20120227

Title: Tyrosine hydroxylase deficiency in Taiwanese infants.

Journal: Pediatric neurology 20120201

Title: The effect of selegiline on total scavenger capacity and liver fat content: a preliminary study in an animal model.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120101

Title: Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120101

Title: Selegiline: a reappraisal of its role in Parkinson disease.

Journal: Clinical neuropharmacology 20120101

Title: Deprenyl prevents MPP(+)-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk.

Journal: Toxicology 20111218

Title: In vivo imaging of astrocytosis in Alzheimer's disease: an ¹¹C-L-deuteriodeprenyl and PIB PET study.

Journal: European journal of nuclear medicine and molecular imaging 20111201

Title: PET imaging for attention deficit preclinical drug testing in neurofibromatosis-1 mice.

Journal: Experimental neurology 20111201

Title: Predicting successful 24-hr quit attempt in a smoking cessation intervention.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20111101

Title: Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report.

Journal: Pharmacopsychiatry 20111101

Title: Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).

Journal: Journal of medicinal chemistry 20111027

Title: Trans-differentiation of the adipose tissue-derived stem cells into neuron-like cells expressing neurotrophins by selegiline.

Journal: Iranian biomedical journal 20111001

Title: Selegiline-functionalized, PEGylated poly(alkyl cyanoacrylate) nanoparticles: Investigation of interaction with amyloid-β peptide and surface reorganization.

Journal: International journal of pharmaceutics 20110920

Title: Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells.

Journal: In vitro cellular & developmental biology. Animal 20110901

Title: Transdermal delivery of selegiline from alginate-Pluronic composite thermogels.

Journal: International journal of pharmaceutics 20110830

Title: CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease.

Journal: Brain research 20110823

Title: Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801

Title: MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins.

Journal: Bioorganic & medicinal chemistry letters 20110715

Title: The relationship between depression and regional cerebral blood flow in Parkinson's disease and the effect of selegiline treatment.

Journal: Acta neurologica Scandinavica 20110701

Title: Differences in smoking expectancies in smokers with and without a history of major depression.

Journal: Addictive behaviors 20110401

Title: Selegiline use is associated with a slower progression in early Parkinson's disease as evaluated by Hoehn and Yahr Stage transition times.

Journal: Parkinsonism & related disorders 20110301

Title: Expanding phenotype and clinical analysis of tyrosine hydroxylase deficiency.

Journal: Journal of child neurology 20110201

Title: Tolerability and efficacy of switching from oral selegiline to Zydis selegiline in patients with Parkinson's disease.

Journal: Parkinsonism & related disorders 20110201

Title: MAO inhibitors.

Journal: Cleveland Clinic journal of medicine 20110201

Title: The anti-Parkinsonian drug selegiline delays the nucleation phase of α-synuclein aggregation leading to the formation of nontoxic species.

Journal: Journal of molecular biology 20110107

Title: Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography.

Journal: Neurochemistry international 20110101

Title: Selegiline and rasagiline: twins or distant cousins?

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20110101

Title: Pharmacotherapy for late-life depression.

Journal: The Journal of clinical psychiatry 20110101

Title: Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro.

Journal: BMC pharmacology 20110101

Title: Elevated [11C]-D-deprenyl uptake in chronic Whiplash Associated Disorder suggests persistent musculoskeletal inflammation.

Journal: PloS one 20110101

Title: Serum cholesterol and the progression of Parkinson's disease: results from DATATOP.

Journal: PloS one 20110101

Title: The pharmacology of selegiline.

Journal: International review of neurobiology 20110101

Title: Selective inhibitors of monoamine oxidase type B and the 'cheese effect'.

Journal: International review of neurobiology 20110101

Title: Supplementation of deprenyl attenuates age associated alterations in rat cerebellum.

Journal: Molecular biology reports 20101201

Title: Clinical pharmacology tyramine challenge study to determine the selectivity of the monoamine oxidase type B (MAO-B) inhibitor rasagiline.

Journal: Journal of clinical pharmacology 20101201

Title: R-deprenyl: pharmacological spectrum of its activity.

Journal: Neurochemical research 20101201

Title: MAO inhibitors: risks, benefits, and lore.

Journal: Cleveland Clinic journal of medicine 20101201

Title: Ring opening of pymisyl-protected aziridines with organocuprates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20101102

Title: Transdermal iontophoretic delivery of selegiline hydrochloride, in vitro.

Journal: Journal of drug targeting 20101101

Title: Rasagiline: a novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity.

Journal: Progress in neurobiology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Orthostatic hypotension: a non-motor complication assessment in 82 patients with idiopathic Parkinson's disease in Phramongkutklao Hospital.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20101101

Title: The fabulous neuroprotection of selegiline: memoir and prospectus.

Journal: Journal of child neurology 20101001

Title: Clozapine for medication-related pathological gambling in Parkinson disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20100915

Title: Age-related protective effect of deprenyl on changes in the levels of diagnostic marker enzymes and antioxidant defense enzymes activities in cerebellar tissue in Wistar rats.

Journal: Cell stress & chaperones 20100901

Title: HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20100901

Title: Changes in smoking expectancies in abstinent, reducing, and non-abstinent participants during a pharmacological trial for smoking cessation.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100901

Title: Failure to improve cigarette smoking abstinence with transdermal selegiline + cognitive behavior therapy.

Journal: Addiction (Abingdon, England) 20100901

Title: [The feasibility of synthetic enhancer substances for preventive nanotherapy].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20100901

Title: Slowing the decline.

Journal: Nature 20100826

Title: Cytoprotective effect of (-)-deprenyl, (-)desmethyl-deprenyl and (-)deprenyl-N-oxide on glutathione depleted A-2058 melanoma cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100601

Title: A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage.

Journal: Biological psychiatry 20100501

Title: Marked improvement in Segawa syndrome after L-dopa and selegiline treatment.

Journal: Pediatric neurology 20100501

Title: [General anaesthesia for neurological diseases].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20100501

Title: Regulation of brain-derived neurotrophic factor (BDNF) and cerebral dopamine neurotrophic factor (CDNF) by anti-parkinsonian drug therapy in vivo.

Journal: Cellular and molecular neurobiology 20100401

Title: Manganese neurotoxic time course is not influenced by L-deprenyl systemic treatment: influence of L-deprenyl in manganese neurotoxic time course.

Journal: Brain research 20100304

Title: Selegiline is an efficient and potent inducer for bone marrow stromal cell differentiation into neuronal phenotype.

Journal: Neurological research 20100301

Title: A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers.

Journal: Drug and alcohol dependence 20100301

Title: [On the role of MAO B inhibitors and NMDA antagonists in the therapy of Parkinson's disease].

Journal: Fortschritte der Neurologie-Psychiatrie 20100301

Title: Cognitive aspects of congenital learned helplessness and its reversal by the monoamine oxidase (MAO)-B inhibitor deprenyl.

Journal: Neurobiology of learning and memory 20100201

Title: (-)-Deprenyl inhibits vascular hyperpermeability after hemorrhagic shock.

Journal: Shock (Augusta, Ga.) 20100101

Title: Orally disintegrating selegiline in Parkinson patients with dopamine agonist-related adverse effects.

Journal: Clinical neuropharmacology 20100101

Title: Early addition of selegiline to L-Dopa treatment is beneficial for patients with Parkinson disease.

Journal: Clinical neuropharmacology 20100101

Title: Frontotemporal dementia and pharmacologic interventions.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20100101

Title: Transdermal selegiline in patients receiving electroconvulsive therapy.

Journal: Psychosomatics 20100101

Title: Electropharmacograms of rasagiline, its metabolite aminoindan and selegiline in the freely moving rat.

Journal: Neuropsychobiology 20100101

Title: Zonisamide attenuates MPTP neurotoxicity in marmosets.

Journal: Journal of pharmacological sciences 20100101

Title: A comparison of treatment thresholds in two large Parkinson's disease clinical trial cohorts.

Journal: Movement disorders : official journal of the Movement Disorder Society 20091215

Title: Selegiline and oxidative stress in HIV-associated cognitive impairment.

Journal: Neurology 20091208

Title: Acidic vesicles of the endo-exocytic pathways as targets for some anti-monoamine oxidase drugs.

Journal: Metabolic brain disease 20091201

Title: [Severe apathy following head injury: improvement with Selegiline treatment].

Journal: Neuro-Chirurgie 20091201

Title: [Slowing the age-induced decline of brain function with prophylactic use of (-)-deprenyl (Selegiline, Jumex). Current international view and conclusions 25 years after the Knoll's proposal].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20091201

Title: Effect of deprenyl on free radical oxidation in rat brain during immobilization stress.

Journal: Bulletin of experimental biology and medicine 20091201

Title: Incidence of and risk factors for cognitive impairment in an early Parkinson disease clinical trial cohort.

Journal: Neurology 20091103

Title: Genomic and proteomic study to survey the mechanism of action of the anti-Parkinson's disease drug, rasagiline compared with selegiline, in the rat midbrain.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091101

Title: Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease.

Journal: The Cochrane database of systematic reviews 20091007

Title: Transdermal permeation of selegiline from hydrogel-membrane drug delivery systems.

Journal: International journal of pharmaceutics 20091001

Title: (-)Deprenyl-N-oxide, a (-)deprenyl metabolite, is cytoprotective after hypoxic injury in PC12 cells, or after transient brain ischemia in gerbils.

Journal: Journal of the neurological sciences 20090815

Title: Serotonin toxicity caused by moclobemide too soon after paroxetine-selegiline.

Journal: Journal of the Chinese Medical Association : JCMA 20090801

Title: Selegiline shortage: Causes and costs of a generic drug shortage.

Journal: Neurology 20090721

Title: Selegiline transdermal system: a novel treatment option for major depressive disorder.

Journal: Expert opinion on pharmacotherapy 20090701

Title: A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090615

Title: Teasing apart drug treatments and individual symptoms in narcolepsy.

Journal: Sleep medicine 20090601

Title: Short-term erythrosine B-induced inhibition of the brain regional serotonergic activity suppresses motor activity (exploratory behavior) of young adult mammals.

Journal: Pharmacology, biochemistry, and behavior 20090601

Title: Involvement of protein trafficking in deprenyl-induced alpha-secretase activity regulation in PC12 cells.

Journal: European journal of pharmacology 20090521

Title: Long-term administration of monoamine oxidase inhibitors alters the firing rate and pattern of dopamine neurons in the ventral tegmental area.

Journal: The international journal of neuropsychopharmacology 20090501

Title: Assessment of MAO-B occupancy in the brain with PET and [11C]-L-deprenyl-D2: a dose-finding study with a novel MAO-B inhibitor, EVT 301.

Journal: Clinical pharmacology and therapeutics 20090501

Title: Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP.

Journal: Journal of pharmacological sciences 20090501

Title: MAO-B inhibitor know-how: back to the pharm.

Journal: Neurology 20090414

Title: Hyperserotonergic phenotype after monoamine oxidase inhibition in larval zebrafish.

Journal: Journal of neurochemistry 20090401

Title: Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.

Journal: Neurotoxicity research 20090401

Title: 'Bad guys' among the antiparkinsonian drugs.

Journal: Psychiatria Danubina 20090301

Title: Antioxidant and antiapoptotic activities of deprenyl and estradiol co-administration in aged rat kidney.

Journal: Acta biologica Hungarica 20090301

Title: Neuroprotection by rasagiline in thiamine deficient rats.

Journal: Brain research 20090223

Title: MPTP and MPP+ target specific aminergic cell populations in larval zebrafish.

Journal: Journal of neurochemistry 20090201

Title: [Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings].

Journal: Ideggyogyaszati szemle 20090130

Title: A case report of high-dose transdermal selegiline in the treatment of major depressive disorder.

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20090101

Title: Investigation of oral selegiline and rasagiline administration on QT interval in conscious rabbits.

Journal: European review for medical and pharmacological sciences 20090101

Title: A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.

Journal: BMC clinical pharmacology 20090101

Title: (-)-Deprenyl inhibits thermal injury-induced apoptotic signaling and hyperpermeability in microvascular endothelial cells.

Journal: Journal of burn care & research : official publication of the American Burn Association 20090101

Title: Serum prolactin as a tool for the follow-up of treated DHPR-deficient patients.

Journal: Journal of inherited metabolic disease 20081201

Title: Antidepressant activity of curcumin: involvement of serotonin and dopamine system.

Journal: Psychopharmacology 20081201

Title: 1-Methyl-4-phenyl-pyridinium ion-induced oxidative stress, c-Jun phosphorylation and DNA fragmentation factor-45 cleavage in SK-N-SH cells are averted by selegiline.

Journal: Neurochemistry international 20081201

Title: The effect of short-term administration of (-)-deprenyl and isatin on the expressions of some genes in the mouse brain cortex.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20081201

Title: Neural progenitor cells are protected against MPTP by MAO-B inhibitors.

Journal: Neurotoxicology 20081101

Title: Orally disintegrating selegiline for the treatment of Parkinson's disease.

Journal: Expert opinion on pharmacotherapy 20081101

Title: Protective effects of deprenyl in transient cerebral ischemia in rats.

Journal: The Chinese journal of physiology 20081031

Title: Apomorphine offers new insight into dopaminergic neuron vulnerability in mesencephalic cultures.

Journal: Neuropharmacology 20081001

Title: Pharmacological treatment in moderate-to-severe Alzheimer's disease.

Journal: Expert opinion on pharmacotherapy 20081001

Title: Detection of levorotatory methamphetamine and levorotatory amphetamine in urine after ingestion of an overdose of selegiline.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001

Title: [Rasagiline in daily clinical use. Results of a treatment study of Parkinson patients with a combination treatment].

Journal: Fortschritte der Neurologie-Psychiatrie 20081001

Title: [Motor symptoms in Parkinson disease].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080925

Title: Fourteen-year final report of the randomized PDRG-UK trial comparing three initial treatments in PD.

Journal: Neurology 20080812

Title: Synergistic effects of selegiline and donepezil on cognitive impairment induced by amyloid beta (25-35).

Journal: Behavioural brain research 20080719

Title: Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration.

Journal: Journal of neurochemistry 20080601

Title: Study of high deprenyl dose on the preimplantation embryo development and lymphocyte DNA in rat.

Journal: General physiology and biophysics 20080601

Title: Selegiline reduces cisplatin-induced neuronal death in neuroblastoma cells.

Journal: Neurological research 20080501

Title: The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B.

Journal: British journal of pharmacology 20080501

Title: Predictors of deterioration in health-related quality of life in Parkinson's disease: results from the DATATOP trial.

Journal: Movement disorders : official journal of the Movement Disorder Society 20080415

Title: Selegilin exerts antidepressant-like effects during the forced swim test in adrenocorticotropic hormone-treated rats.

Journal: Journal of pharmacological sciences 20080401

Title: Optimization and validation of a dissolution test for selegiline hydrochloride tablets by a novel rapid HPLC assay using a monolithic stationary phase.

Journal: Journal of pharmaceutical and biomedical analysis 20080313

Title: Efficacy of selegiline add on therapy to risperidone in the treatment of the negative symptoms of schizophrenia: a double-blind randomized placebo-controlled study.

Journal: Human psychopharmacology 20080301

Title: Selegiline is a mechanism-based inactivator of CYP2A6 inhibiting nicotine metabolism in humans and mice.

Journal: The Journal of pharmacology and experimental therapeutics 20080301

Title: Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.

Journal: Neurotoxicology 20080301

Title: [A comparison of the pharmacology of (-)-deprenyl to N-methylpropargylamine-1-aminoindane (J-508) and rasagiline, the desmethyl-analogue of J-508].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20080301

Title: [Role of apoptosis in the kidney after reperfusion].

Journal: Orvosi hetilap 20080217

Title: Transdermal selegiline: new opportunity for managing depression.

Journal: The Journal of the American Osteopathic Association 20080201

Title: [The use of Stalevo in Hungary for patients with Parkinson disease and its effect on the quality of life].

Journal: Ideggyogyaszati szemle 20080130

Title: Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for 'in competition' anti-doping analysis.

Journal: Analytica chimica acta 20080114

Title: The selegiline transdermal system in major depressive disorder: a systematic review of safety and tolerability.

Journal: Journal of affective disorders 20080101

Title: Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080101

Title: Neurobehavioral protection by single dose l-deprenyl against MPTP-induced parkinsonism in common marmosets.

Journal: Psychopharmacology 20080101

Title: Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.

Journal: Journal of psychiatric practice 20080101

Title: Effect of MAO-B inhibition against ischemia-induced oxidative stress in the rat brain. Comparison with a rational antioxidant.

Journal: Arzneimittel-Forschung 20080101

Title: Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum.

Journal: Pharmacological reports : PR 20080101

Title: Antagonistic effect of low deprenyl dose on the preimplantation embryo development in rat.

Journal: Bratislavske lekarske listy 20080101

Title: Possible new antiaging strategies related to neuroendocrine-immune interactions.

Journal: Neuroimmunomodulation 20080101

Title: Differential effects of selegiline on glucose synthesis in rabbit kidney-cortex tubules and hepatocytes. In vitro and in vivo studies.

Journal: Chemico-biological interactions 20071215

Title: In vitro metabolism of the analgesic bicifadine in the mouse, rat, monkey, and human.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Monoamine oxidase-B inhibition in the treatment of Parkinson's disease.

Journal: Pharmacotherapy 20071201

Title: Symptoms of sexual dysfunction in patients treated for major depressive disorder: a meta-analysis comparing selegiline transdermal system and placebo using a patient-rated scale.

Journal: The Journal of clinical psychiatry 20071201

Title: Deprenyl treatment attenuates long-term pre- and post-synaptic changes evoked by chronic methamphetamine.

Journal: European journal of pharmacology 20071114

Title: Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats.

Journal: Psychopharmacology 20071101

Title: Bystander effects of ionizing radiation can be modulated by signaling amines.

Journal: Environmental research 20071001

Title: Pharmacokinetics and absolute bioavailability of selegiline following treatment of healthy subjects with the selegiline transdermal system (6 mg/24 h): a comparison with oral selegiline capsules.

Journal: Journal of clinical pharmacology 20071001

Title: Zydis selegiline in the management of Parkinson's disease.

Journal: Expert opinion on pharmacotherapy 20071001

Title: A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment.

Journal: Neurology 20070925

Title: Lost in translation: again, another failed neuroprotection trial.

Journal: Neurology 20070925

Title: Amine oxidases and their inhibitors: what can they tell us about neuroprotection and the development of drugs for neuropsychiatric disorders?

Journal: Journal of psychiatry & neuroscience : JPN 20070901

Title: Comprehensive review of rasagiline, a second-generation monoamine oxidase inhibitor, for the treatment of Parkinson's disease.

Journal: Clinical therapeutics 20070901

Title: A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: pharmacological validation with R-(-)-deprenyl.

Journal: Journal of neuroscience methods 20070815

Title: Selegiline transdermal system: current awareness and promise.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070815

Title: Evaluation of the potential for pharmacodynamic and pharmacokinetic drug interactions between selegiline transdermal system and two sympathomimetic agents (pseudoephedrine and phenylpropanolamine) in healthy volunteers.

Journal: Journal of clinical pharmacology 20070801

Title: Low plasma uric acid level in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070615

Title: The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by two series of novel carbamates.

Journal: Molecular pharmacology 20070601

Title: Antioxidant effects of selegiline in oxidative stress induced by iron neonatal treatment in rats.

Journal: Neurochemical research 20070601

Title: Therapeutic advances in narcolepsy.

Journal: Sleep medicine 20070601

Title: Treatment-resistant depression: response to low-dose transdermal but not oral selegiline.

Journal: Journal of clinical psychopharmacology 20070601

Title: Transdermal selegiline.

Journal: Drugs of today (Barcelona, Spain : 1998) 20070601

Title: Rasagiline as a therapy for Parkinson's disease (PD).

Journal: The American journal of geriatric pharmacotherapy 20070601

Title: Anti-fibrillogenic and fibril-destabilizing activities of anti-Parkinsonian agents for alpha-synuclein fibrils in vitro.

Journal: Journal of neuroscience research 20070515

Title: The role of selegiline in the treatment of negative symptoms associated with schizophrenia.

Journal: The Annals of pharmacotherapy 20070501

Title: Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain.

Journal: Journal of ethnopharmacology 20070420

Title: Evidence for astrocytosis in ALS demonstrated by [11C](L)-deprenyl-D2 PET.

Journal: Journal of the neurological sciences 20070415

Title: Safety and efficacy of newly formulated selegiline orally disintegrating tablets as an adjunct to levodopa in the management of 'off' episodes in patients with Parkinson's disease.

Journal: Current medical research and opinion 20070401

Title: Translating the evidence on atypical depression into clinical practice.

Journal: The Journal of clinical psychiatry 20070401

Title: P450 phenotyping of the metabolism of selegiline to desmethylselegiline and methamphetamine.

Journal: Drug metabolism and pharmacokinetics 20070401

Title: Involvement of cytochromes P450 2D6, 2B6 and 2C19 in the metabolism of (-)-deprenyl and N-methyl,N-propargylphenylethylamine.

Journal: Drug metabolism letters 20070401

Title: Oxygen-glucose deprivation-induced changes in organotypic cultures of the rat hippocampus.

Journal: Ideggyogyaszati szemle 20070330

Title: Metabolism of N-methyl, N-propargylphenylethylamine: studies with human liver microsomes and cDNA expressed cytochrome P450 (CYP) enzymes.

Journal: Cellular and molecular neurobiology 20070301

Title: Selegiline and blood pressure in patients with Parkinson's disease.

Journal: Acta neurologica Scandinavica 20070201

Title: Selegiline transdermal system: an examination of the potential for CYP450-dependent pharmacokinetic interactions with 3 psychotropic medications.

Journal: Journal of clinical pharmacology 20070201

Title: Antioxidants and Alzheimer's disease: time to stop feeding vitamin E to dementia patients?

Journal: International psychogeriatrics 20070201

Title: Separation of enantiomers of deprenyl with various CDs in CE and the effect of enantiomer migration order on enantiomeric impurity determination of selegiline in active ingredients and tablets.

Journal: Electrophoresis 20070201

Title: Psychopharmacology column: why choose selegiline transdermal system for refractory depression?

Journal: Issues in mental health nursing 20070201

Title: Management of sexual dysfunction due to antipsychotic drug therapy.

Journal: The Cochrane database of systematic reviews 20070124

Title: Improvement of mouse brain mitochondrial function after deprenyl treatment.

Journal: Neuroscience 20070119

Title: Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPalpha secretion by deprenyl.

Journal: Neurochemistry international 20070101

Title: Chronic (-)-deprenyl administration attenuates dendritic developmental impairment induced by early social isolation in the rat.

Journal: Developmental neuroscience 20070101

Title: Seligiline transdermal system in depression.

Journal: Expert opinion on pharmacotherapy 20070101

Title: Effects of a tyramine-enriched meal on blood pressure response in healthy male volunteers treated with selegiline transdermal system 6 mg/24 hour.

Journal: CNS spectrums 20070101

Title: Selegiline transdermal system: in the treatment of major depressive disorder.

Journal: Drugs 20070101

Title: The effect of l-deprenyl on tissue mRNA expressions of NOS isoforms and NO levels in an experimental diabetes mellitus model.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070101

Title: Selegiline transdermal system in major depressive disorder: profile report.

Journal: CNS drugs 20070101

Title: Monamine oxidase inhibitors: current and emerging agents for Parkinson disease.

Journal: Clinical neuropharmacology 20070101

Title: Suppression of apoptosis and oxidative stress by deprenyl and estradiol in aged rat liver.

Journal: Acta histochemica 20070101

Title: Community and long-term care management of Parkinson's disease in the elderly: focus on monoamine oxidase type B inhibitors.

Journal: Drugs & aging 20070101

Title: Selegiline orally disintegrating tablets in patients with Parkinson disease and 'wearing off' symptoms.

Journal: Clinical neuropharmacology 20070101

Title: Placebo response in Parkinson trials using patient diaries: sites do matter.

Journal: Clinical neuropharmacology 20070101

Title: A perspective on adjunctive therapy for Parkinson disease with monoamine oxidase-B inhibition.

Journal: Clinical neuropharmacology 20070101

Title: Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers.

Journal: Journal of neural transmission. Supplementum 20070101

Title: Pharmacokinetic studies of (-)-deprenyl and some of its metabolites in mouse.

Journal: Journal of neural transmission. Supplementum 20070101

Title: Treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials.

Journal: Psychopharmacology bulletin 20070101

Title: Commentary on the treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials.

Journal: Psychopharmacology bulletin 20070101

Title: Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090.

Journal: HIV clinical trials 20070101

Title: Simultaneous determination of selegiline and desmethylselegiline in human body fluids by headspace solid-phase microextraction and gas chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205

Title: Double-blind, placebo-controlled trial of selegiline transdermal system (STS) for the treatment of cocaine dependence.

Journal: Drug and alcohol dependence 20061201

Title: Selegiline transdermal system in the prevention of relapse of major depressive disorder: a 52-week, double-blind, placebo-substitution, parallel-group clinical trial.

Journal: Journal of clinical psychopharmacology 20061201

Title: L-methamphetamine and selective MAO inhibitors decrease morphine-reinforced and non-reinforced behavior in rats; Insights towards selegiline's mechanism of action.

Journal: Pharmacology, biochemistry, and behavior 20061201

Title: The path from anti Parkinson drug selegiline and rasagiline to multifunctional neuroprotective anti Alzheimer drugs ladostigil and m30.

Journal: Current Alzheimer research 20061201

Title: Monoamine oxidase inhibitory coumarins from the aerial parts of Dictamnus albus.

Journal: Archives of pharmacal research 20061201

Title: A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [11C]-GR205171, [11C]-L-deuterium-deprenyl, [11C]-5-Hydroxy-L-Tryptophan, [11C]-L-DOPA and Pittsburgh Compound-B.

Journal: NeuroImage 20061101

Title: Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases.

Journal: Current drug targets 20061101

Title: Acute effects of moclobemide and deprenyl on 5-HT synthesis rates in the rat brain: An autoradiographic study.

Journal: Brain research bulletin 20061016

Title: Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20061001

Title: A systematic review of research on strategies for the management of antipsychotic-induced sexual dysfunction: high-level evidence is needed.

Journal: The Journal of clinical psychiatry 20061001

Title: Hypersexuality and paraphilia induced by selegiline in Parkinson's disease: report of 2 cases.

Journal: Parkinsonism & related disorders 20060901

Title: Selegiline transdermal system for the treatment of major depressive disorder: an 8-week, double-blind, placebo-controlled, flexible-dose titration trial.

Journal: The Journal of clinical psychiatry 20060901

Title: The combined use of human neural and liver cell lines and mouse hepatocytes improves the predictability of the neurotoxicity of selected drugs.

Journal: Toxicology letters 20060820

Title: Cytoprotective effect of two synthetic enhancer substances, (-)-BPAP and (-)-deprenyl, on human brain capillary endothelial cells and rat PC12 cells.

Journal: Life sciences 20060808

Title: (-)-Trans-epsilon-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity.

Journal: European journal of pharmacology 20060807

Title: Tyramine pressor sensitivity during treatment with the selegiline transdermal system 6 mg/24 h in healthy subjects.

Journal: Journal of clinical pharmacology 20060801

Title: Effects of subchronic treatment with selegiline on L-DOPA-induced increase in extracellular dopamine level in rat striatum.

Journal: Journal of pharmacological sciences 20060801

Title: Placebo-controlled study examining effects of selegiline in children with attention-deficit/hyperactivity disorder.

Journal: Journal of child and adolescent psychopharmacology 20060801

Title: A new way to deliver psychiatric meds.

Journal: Behavioral healthcare 20060801

Title: Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.

Journal: The Cochrane database of systematic reviews 20060719

Title: [Molecular mechanisms of the neuroprotective effect of (-)-deprenyl].

Journal: Orvosi hetilap 20060709

Title: L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats.

Journal: Neurochemistry international 20060701

Title: Neuroprotective role of Bacopa monniera extract against aluminium-induced oxidative stress in the hippocampus of rat brain.

Journal: Neurotoxicology 20060701

Title: Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.

Journal: Neurobiology of disease 20060701

Title: Transdermal selegiline: a novel MAOI formulation for depression.

Journal: Journal of psychosocial nursing and mental health services 20060701

Title: Disease progression and pharmacodynamics in Parkinson disease - evidence for functional protection with levodopa and other treatments.

Journal: Journal of pharmacokinetics and pharmacodynamics 20060601

Title: High-throughput screening for monoamine oxidase-A and monoamine oxidase-B inhibitors using one-step fluorescence assay.

Journal: Acta pharmacologica Sinica 20060601

Title: Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease.

Journal: Neurology 20060523

Title: Transdermal selegiline (Emsam).

Journal: The Medical letter on drugs and therapeutics 20060522

Title: Initial pharmacotherapy in a population of veterans with Parkinson disease.

Journal: Neurology 20060509

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Leading the way: advances in the diagnosis, treatment, and management of neuropsychiatric illnesses.

Journal: CNS spectrums 20060501

Title: Transdermal selegiline: the new generation of monoamine oxidase inhibitors.

Journal: CNS spectrums 20060501

Title: Why the transdermal delivery of selegiline (6 mg/24 hr) obviates the need for a dietary restriction on tyramine.

Journal: Journal of psychiatric practice 20060501

Title: Amphetamine-induced locomotor activity is reduced in mice following MPTP treatment but not following selegiline/MPTP treatment.

Journal: Pharmacology, biochemistry, and behavior 20060501

Title: High-performance liquid chromatographic-mass spectrometric determination of methamphetamine and amphetamine enantiomers, desmethylselegiline and selegiline, in hair samples of long-term methamphetamine abusers or selegiline users.

Journal: Journal of analytical toxicology 20060501

Title: The necessity of having a proper dose of (-)deprenyl (D) to prolong the life spans of rats explains discrepancies among different studies in the past.

Journal: Annals of the New York Academy of Sciences 20060501

Title: Selegiline slows the progression of the symptoms of Parkinson disease.

Journal: Neurology 20060425

Title: Patient page. Slowing down a 'slow' movement disorder: selegiline's benefit in treating Parkinson disease.

Journal: Neurology 20060425

Title: Metabolic transformation plays a primary role in the psychostimulant-like discriminative-stimulus effects of selegiline [(R)-(-)-deprenyl].

Journal: The Journal of pharmacology and experimental therapeutics 20060401

Title: Novel transdermal delivery formulation of the monoamine oxidase inhibitor selegiline nearing release for treatment of depression.

Journal: The Journal of clinical psychiatry 20060401

Title: Effects of co-administration of a selective serotonin reuptake inhibitor and monoamine oxidase inhibitors on 5-HT-related behavior in rats.

Journal: European journal of pharmacology 20060227

Title: The use of LC/MS, GC/MS, and LC/NMR hyphenated techniques to identify a drug degradation product in pharmaceutical development.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: Effects of selegiline on antioxidant systems in the nigrostriatum in rat.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060201

Title: Modulation of brain mitochondrial function by deprenyl.

Journal: Neurochemistry international 20060201

Title: Clomipramine and selegiline: do they influence impulse control?

Journal: Journal of veterinary pharmacology and therapeutics 20060201

Title: H MRS identifies lactate rise in the striatum of MPTP-treated C57BL/6 mice.

Journal: The European journal of neuroscience 20060201

Title: Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins.

Journal: Biochemical and biophysical research communications 20060120

Title: Acute and delayed effect of (-) deprenyl and (-) 1-phenyl-2-propylaminopentane (PPAP) on the serotonin content of peritoneal cells (white blood cells and mast cells).

Journal: Cell biochemistry and function 20060101

Title: Deprenyl and the relationship between its effects on spatial memory, oxidant stress and hippocampal neurons in aged male rats.

Journal: Physiological research 20060101

Title: Chronic exposure of rats to cognition enhancing drugs produces a neuroplastic response identical to that obtained by complex environment rearing.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060101

Title: Major depression and the synthetic enhancer substances, (-)-deprenyl and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20060101

Title: A comparison of drug-seeking behavior maintained by D-amphetamine, L-deprenyl (selegiline), and D-deprenyl under a second-order schedule in squirrel monkeys.

Journal: Psychopharmacology 20060101

Title: Efficacy and safety of high-dose cabergoline in Parkinson's disease.

Journal: Acta neurologica Scandinavica 20060101

Title: Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness.

Journal: British journal of pharmacology 20060101

Title: Effect of nerodilol, carvone and anethole on the in vitro transdermal delivery of selegiline hydrochloride.

Journal: Die Pharmazie 20060101

Title: Treatment of primary progressive freezing of gait with high doses of selegiline.

Journal: Clinical neuropharmacology 20060101

Title: Persistent sexual side effects after SSRI discontinuation.

Journal: Psychotherapy and psychosomatics 20060101

Title: Quality of life in Parkinson's disease--Indian scenario.

Journal: The Journal of the Association of Physicians of India 20060101

Title: Contemporary issues in the treatment of Alzheimer's disease: tangible benefits of current therapies.

Journal: The Journal of clinical psychiatry 20060101

Title: Variation in neurophysiological function and evidence of quantitative electroencephalogram discordance: predicting cocaine-dependent treatment attrition.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20060101

Title: First depression patch approved.

Journal: FDA consumer 20060101

Title: [Interaction of pyruvate kinase with isatin and deprenyl].

Journal: Biomeditsinskaia khimiia 20060101

Title: Therapeutic options for cognitive decline in senior pets.

Journal: Journal of the American Animal Hospital Association 20060101

Title: Selegiline induces neuronal phenotype and neurotrophins expression in embryonic stem cells.

Journal: Rejuvenation research 20060101

Title: Isatin interaction with glyceraldehyde-3-phosphate dehydrogenase, a putative target of neuroprotective drugs: partial agonism with deprenyl.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Deprenyl: from chemical synthesis to neuroprotection.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Low dose (-)deprenyl is cytoprotective: it maintains mitochondrial membrane potential and eliminates oxygen radicals.

Journal: Life sciences 20051205

Title: A comprehensive assessment of the safety of intravenous methamphetamine administration during treatment with selegiline.

Journal: Pharmacology, biochemistry, and behavior 20051201

Title: Dementia.

Journal: Clinical evidence 20051201

Title: Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.

Journal: Brain research. Molecular brain research 20051130

Title: Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.

Journal: Brain research. Molecular brain research 20051118

Title: Increased cell-cell adhesion, a novel effect of R-(-)-deprenyl.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20051101

Title: Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl.

Journal: Molecular pharmacology 20051101

Title: Selegiline protects against recognition memory impairment induced by neonatal iron treatment.

Journal: Experimental neurology 20051101

Title: Harmane inhibits serotonergic dorsal raphe neurons in the rat.

Journal: Psychopharmacology 20051101

Title: Parkinson's disease and sleep.

Journal: Neurologic clinics 20051101

Title: Selegiline orally disintegrating tablets for the treatment of Parkinson's disease.

Journal: Expert review of neurotherapeutics 20051101

Title: Recent advances in Parkinson's disease therapy: use of monoamine oxidase inhibitors.

Journal: Expert review of neurotherapeutics 20051101

Title: Would caregivers of Alzheimer disease patients involve their relative in a decision to use an AD-slowing medication?

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20051101

Title: 2-Phenylethylamine in combination with l-deprenyl lowers the striatal level of dopamine and prolongs the duration of the stereotypy in mice.

Journal: Pharmacology, biochemistry, and behavior 20051101

Title: Effects of monoamine oxidase inhibitors on methamphetamine-induced stereotypy in mice and rats.

Journal: Neurochemical research 20051101

Title: Discriminative stimulus and reinforcing effects of p-fluoro-L-deprenyl in monkeys.

Journal: Psychopharmacology 20051001

Title: Antidepressant-like effects of selegiline in the forced swim test.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051001

Title: In vivo measurement of brain monoamine oxidase B occupancy by rasagiline, using (11)C-l-deprenyl and PET.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051001

Title: Protein aggregation in retinal cells and approaches to cell protection.

Journal: Cellular and molecular neurobiology 20050901

Title: Effects of selegiline alone or with donepezil on memory impairment in rats.

Journal: European journal of pharmacology 20050822

Title: LED fluorescence spectroscopy for direct determination of monoamine oxidase B inactivation.

Journal: Analytical biochemistry 20050815

Title: Clinical pharmacology of rasagiline: a novel, second-generation propargylamine for the treatment of Parkinson disease.

Journal: Journal of clinical pharmacology 20050801

Title: Reexamination of the TEMPO Study.

Journal: Archives of neurology 20050801

Title: Rasagiline.

Journal: Nature reviews. Drug discovery 20050801

Title: Monoamine oxidase B inhibitors for early Parkinson's disease.

Journal: The Cochrane database of systematic reviews 20050720

Title: Evidence for reduced arterial plasma input, prolonged lung retention and reduced lung monoamine oxidase in smokers.

Journal: Nuclear medicine and biology 20050701

Title: Detection of N-monomethyl-lysine generated by metabolic transmethylation.

Journal: Analytical and bioanalytical chemistry 20050601

Title: Contribution of L-3,4-dihydroxyphenylalanine metabolism to the inhibition of gluconeogenesis in rabbit kidney-cortex tubules.

Journal: The international journal of biochemistry & cell biology 20050601

Title: Administration of selegiline is not associated with visual hallucinations in advanced Parkinson's disease patients.

Journal: Parkinsonism & related disorders 20050601

Title: Reversal of age-related deficits in object recognition memory in rats with l-deprenyl.

Journal: Experimental gerontology 20050601

Title: Parkinson's disease.

Journal: Clinical evidence 20050601

Title: Parkinson's disease. Diagnosis and the initiation of therapy.

Journal: Minerva medica 20050601

Title: Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.

Journal: Movement disorders : official journal of the Movement Disorder Society 20050501

Title: [A case of interval form of carbon monoxide poisoning with a remarkable recovery].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20050501

Title: Mechanism of 1-methyl-4-phenylpyridinium-induced dopamine release from PC12 cells.

Journal: Neurochemical research 20050501

Title: HPLC and HPLC-MS analysis of urinary N(epsilon)-monomethyl-lysine.

Journal: Journal of chromatographic science 20050401

Title: [Role of R-(-)-deprenyl in adhesion of neuronal and non-neuronal cells].

Journal: Orvosi hetilap 20050327

Title: 'Levodopa phobia': a new iatrogenic cause of disability in Parkinson disease.

Journal: Neurology 20050308

Title: Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice.

Journal: Neuroscience research 20050301

Title: Therapeutic agents for the treatment of cognitive dysfunction syndrome in senior dogs.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20050301

Title: Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002.

Journal: Synapse (New York, N.Y.) 20050201

Title: The effects of acute loading with levodopa and levodopa with selegiline on blood pressure and plasma norepinephrine levels in chronic Parkinson's disease patients.

Journal: Acta neurologica Scandinavica 20050201

Title: Double-blind, placebo-controlled, multicenter trial of selegiline augmentation of antipsychotic medication to treat negative symptoms in outpatients with schizophrenia.

Journal: The American journal of psychiatry 20050201

Title: Effects of high-dose selegiline on morphine reinforcement and precipitated withdrawal in dependent rats.

Journal: Behavioural pharmacology 20050201

Title: Selegiline in the management of apathy following traumatic brain injury.

Journal: Brain injury 20050201

Title: Survival in Parkinson disease: thirteen-year follow-up of the DATATOP cohort.

Journal: Neurology 20050111

Title: Selegiline modifies the extinction of responding following morphine self-administration, but does not alter cue-induced reinstatement, reacquisition of morphine reinforcement, or precipitated withdrawal.

Journal: Pharmacological research 20050101

Title: Molecular characterization of monoamine oxidase in zebrafish (Danio rerio).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101

Title: Marked effect of liver and kidney function on the pharmacokinetics of selegiline.

Journal: Clinical pharmacology and therapeutics 20050101

Title: Intracellular dopamine oxidation mediates rotenone-induced apoptosis in PC12 cells.

Journal: Acta pharmacologica Sinica 20050101

Title: Inhibition of methamphetamine-induced hyperlocomotion in mice by clorgyline, a monoamine oxidase-a inhibitor, through alteration of the 5-hydroxytriptamine turnover in the striatum.

Journal: Neuroscience 20050101

Title: sgk1, a member of an RNA cluster associated with cell death in a model of Parkinson's disease.

Journal: The European journal of neuroscience 20050101

Title: Other pharmacological treatments for motor complications and dyskinesias.

Journal: Movement disorders : official journal of the Movement Disorder Society 20050101

Title: Dislocation of the glenoid fossa.

Journal: Journal of shoulder and elbow surgery 20050101

Title: 'My involvement in aging research was just a series of coincidences' An interview with Kenichi Kitani. Interview by Sataro Goto.

Journal: Biogerontology 20050101

Title: Remarkable effect of selegiline (L-deprenyl), a selective monoamine oxidase type-B inhibitor, in a patient with severe refractory depression: a case report.

Journal: Clinical neuropharmacology 20050101

Title: A rapid, sensitive electron-capture gas chromatographic procedure for analysis of metabolites of N-methyl,N-propargylphenylethylamine, a potential neuroprotective agent.

Journal: Journal of pharmacological and toxicological methods 20050101

Title: Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model.

Journal: Endocrine research 20050101

Title: Dose-dependency of life span prolongation of F344/DuCrj rats injected with (-)deprenyl.

Journal: Biogerontology 20050101

Title: [Alzheimer's disease therapy--theory and practice].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20050101

Title: Deprenyl, a therapeutic agent for Parkinson's disease, inhibits arsenic toxicity potentiated by GSH depletion via inhibition of JNK activation.

Journal: Journal of toxicology and environmental health. Part A 20041201

Title: Indolalkylamines derivatives as antioxidant and neuroprotective agents in an experimental model of Parkinson's disease.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20041201

Title: Treatment possibilities of Alzheimer's disease.

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20041201

Title: The use of the synthetic enhancer substances (-)-deprenyl and (-)-BPAP in major depression.

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20041201

Title: Preclinical evidence for neuroprotection with monoamine oxidase-B inhibitors in Parkinson's disease.

Journal: Neurology 20041012

Title: A novel formulation of selegiline for the treatment of Parkinson's disease.

Journal: Neurology 20041012

Title: Clinical trials of neuroprotection for Parkinson's disease.

Journal: Neurology 20041012

Title: A review of the mechanisms and role of monoamine oxidase inhibitors in Parkinson's disease.

Journal: Neurology 20041012

Title: Cardiovascular activity of rasagiline, a selective and potent inhibitor of mitochondrial monoamine oxidase B: comparison with selegiline.

Journal: British journal of pharmacology 20041001

Title: Levodopa-responsive parkinsonism in hereditary spastic paraplegia with thin corpus callosum.

Journal: Parkinsonism & related disorders 20041001

Title: In vitro confirmation of selegiline N-oxidation by flavin-containing monooxygenase in rat microsome using LC-ESI MS.

Journal: Biological & pharmaceutical bulletin 20041001

Title: Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice.

Journal: European journal of pharmacology 20040919

Title: Pitfalls of animal model systems in ageing research.

Journal: Best practice & research. Clinical endocrinology & metabolism 20040901

Title: Effects of repeated administration of Uncaria hooks on the acquisition and central neuronal activities in ethanol-treated mice.

Journal: Journal of ethnopharmacology 20040901

Title: (-)-Deprenyl alleviates the degenerative changes induced in the neonatal rat spinal cord by CSF from amyotrophic lateral sclerosis patients.

Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040901

Title: High-performance liquid chromatography/tandem mass spectrometry assay for the determination of 1-methyl-4-phenyl pyridinium (MPP+) in brain tissue homogenates.

Journal: Journal of neuroscience methods 20040830

Title: 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake transporter, and monoamine oxidase-B.

Journal: Neuroscience letters 20040826

Title: Subthalamic deep brain stimulation masking possible malignant syndrome in Parkinson disease.

Journal: Neurology 20040810

Title: Pharmacological aspects of (-)-deprenyl.

Journal: Current medicinal chemistry 20040801

Title: Assessment of the N-oxidation of deprenyl, methamphetamine, and amphetamine enantiomers by chiral capillary electrophoresis: an in vitro metabolism study.

Journal: Electrophoresis 20040801

Title: Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040801

Title: Selegiline potentiates the effects of EGb 761 in response to ischemic brain injury.

Journal: Neurochemistry international 20040701

Title: Selegiline, an MAO-B inhibitor, attenuates airway smooth muscle contraction in the rat trachea.

Journal: The Journal of pharmacy and pharmacology 20040701

Title: Selegiline increases heme oxygenase-1 expression and the cytotoxicity produced by dopamine treatment of neuroblastoma SK-N-SH cells.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040701

Title: Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs.

Journal: Toxicology letters 20040615

Title: Therapeutic factors causing hallucination in Parkinson's disease patients, especially those given selegiline.

Journal: Parkinsonism & related disorders 20040601

Title: Dementia.

Journal: Clinical evidence 20040601

Title: Parkinson's disease.

Journal: Clinical evidence 20040601

Title: 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells.

Journal: Journal of neuroscience research 20040515

Title: Pharmacological studies with endogenous enhancer substances: beta-phenylethylamine, tryptamine, and their synthetic derivatives.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20040501

Title: Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells.

Journal: Investigative ophthalmology & visual science 20040501

Title: A 'cure' for Parkinson's disease: can neuroprotection be proven with current trial designs?

Journal: Movement disorders : official journal of the Movement Disorder Society 20040501

Title: Inefficacy of selegiline in treatment of canine pituitary-dependent hyperadrenocorticism.

Journal: Australian veterinary journal 20040501

Title: Comparison of the binding of the irreversible monoamine oxidase tracers, [(11)C]clorgyline and [(11)C]l-deprenyl in brain and peripheral organs in humans.

Journal: Nuclear medicine and biology 20040401

Title: Cardiopulmonary effects of medetomidine, oxymorphone, or butorphanol in selegiline-treated dogs.

Journal: Veterinary anaesthesia and analgesia 20040401

Title: Zydis selegiline reduces off time in Parkinson's disease patients with motor fluctuations: a 3-month, randomized, placebo-controlled study.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040401

Title: Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs.

Journal: Acta neuropathologica 20040301

Title: (-)-Deprenyl inhibits tyramine-induced noradrenaline release, but not tyramine-induced dopamine release or potassium-induced noradrenaline release, from rat brain synaptosomes.

Journal: Pharmacological research 20040301

Title: Transdermal selegiline and intravenous cocaine: safety and interactions.

Journal: Psychopharmacology 20040201

Title: l-Deprenyl prevents lipid peroxidation and memory deficits produced by cerebral ischemia in rats.

Journal: Cellular and molecular neurobiology 20040201

Title: Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline.

Journal: Neuroscience letters 20040130

Title: Positive effects of deprenyl and estradiol on spatial memory and oxidant stress in aged female rat brains.

Journal: Neuroscience letters 20040116

Title: Comparative study of the effects of isatin, an endogenous MAO-inhibitor, and selegiline on bradykinesia and dopamine levels in a rat model of Parkinson's disease induced by the Japanese encephalitis virus.

Journal: Neurotoxicology 20040101

Title: (-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.

Journal: Neurotoxicology 20040101

Title: Adverse effects of dopamine potentiation by long-term treatment with selegiline.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040101

Title: Chiral separation of deprenyl-N-oxide isomers by capillary electrophoresis using various cyclodextrin derivatives.

Journal: Journal of chromatographic science 20040101

Title: [Prognosis in Alzheimer's disease].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040101

Title: Effects of the DT-diaphorase inhibitor dicumarol on striatal monoamine levels in L-DOPA and L-deprenyl pre-treated rats.

Journal: Neurotoxicity research 20040101

Title: Brain cholinesterases: III. Future perspectives of AD research and clinical practice.

Journal: Medical hypotheses 20040101

Title: Effects of dopaminergic treatment on bladder function in Parkinson's disease.

Journal: Neurourology and urodynamics 20040101

Title: In vitro formation of selegiline-N-oxide as a metabolite of selegiline in human, hamster, mouse, rat, guinea-pig, rabbit and dog.

Journal: European journal of drug metabolism and pharmacokinetics 20040101

Title: [The effect of long-term administration of isatin and himantan to mice on sensitivity of brain monoamine oxidase B to inhibition by deprenyl in vivo and in vitro].

Journal: Biomeditsinskaia khimiia 20040101

Title: Selegiline in comparison with methylphenidate in attention deficit hyperactivity disorder children and adolescents in a double-blind, randomized clinical trial.

Journal: Journal of child and adolescent psychopharmacology 20040101

Title: Increased striatal neuropeptide Y immunoreactivity and its modulation by deprenyl, clonidine and L-dopa in MPTP-treated mice.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031201

Title: Analysis of benzene ethylamine derivatives in urine using the programmable dynamic liquid-phase microextraction (LPME) device.

Journal: The Analyst 20031201

Title: The effects of chronic administration of inhibitors of flavin and quinone amine oxidases on imidazoline I(1) receptor density in rat whole brain.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Relationship between imidazoline(2) sites and monoamine oxidase.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Pro-apoptotic and anti-apoptotic molecules affecting pathways of signal transduction.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Parkinson's disease.

Journal: Clinical evidence 20031201

Title: Reduced cardiovascular effects of methamphetamine following treatment with selegiline.

Journal: Drug and alcohol dependence 20031124

Title: Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity.

Journal: British journal of cancer 20031117

Title: Transdermal selegiline: targeted effects on monoamine oxidases in the brain.

Journal: Biological psychiatry 20031115

Title: L-Deprenyl as an inhibitor of menadione-induced permeability transition in liver mitochondria.

Journal: Biochemical pharmacology 20031101

Title: Clinical inquiries. What is the best initial treatment of Parkinson's disease?

Journal: The Journal of family practice 20031101

Title: Selegiline reduces N-methyl-D-aspartic acid induced perturbation of neurotransmission but it leaves NMDA receptor dependent long-term potentiation intact in the hippocampus.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031101

Title: A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031101

Title: A new low-dose formulation of selegiline: clinical efficacy, patient preference and selectivity for MAO-B inhibition.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031101

Title: Selegiline's neuroprotective capacity revisited.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031101

Title: L-DOPA-induced excessive daytime sleepiness in PD: a placebo-controlled case with MSLT assessment.

Journal: Neurology 20031014

Title: D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity.

Journal: Synapse (New York, N.Y.) 20031001

Title: A randomized controlled trial of oral selegiline plus nicotine skin patch compared with placebo plus nicotine skin patch for smoking cessation.

Journal: Addiction (Abingdon, England) 20031001

Title: Pharmacologic treatment of Alzheimer's disease: an update.

Journal: American family physician 20031001

Title: Sublingual selegiline: new formulation. New formulation: new risk of oral adverse effects.

Journal: Prescrire international 20031001

Title: L-selegiline potentiates the cellular poly(ADP-ribosyl)ation response to ionizing radiation.

Journal: The Journal of pharmacology and experimental therapeutics 20030901

Title: Selegiline long-term effects on brain acetylcholinesterase, (Na+,K+)-ATPase activities, antioxidant status and learning performance of aged rats.

Journal: Pharmacological research 20030901

Title: Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations.

Journal: Journal of neurochemistry 20030901

Title: Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030901

Title: Deprenyl blocks the aglycemia-induced depression of the synaptic transmission but not the ischemia-induced depression in neonatal rat spinal cord in vitro.

Journal: Neuroscience research 20030901

Title: Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD.

Journal: Neurology 20030812

Title: [Therapy for patients with early-stage Parkinson's disease].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20030810

Title: Enhancer regulation/endogenous and synthetic enhancer compounds: a neurochemical concept of the innate and acquired drives.

Journal: Neurochemical research 20030801

Title: Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture.

Journal: Neuroscience research 20030801

Title: Effects of monoamine oxidase inhibitors on the diethyldithiocarbamate-induced enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in C57BL/6 mice.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030801

Title: Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030801

Title: Chiral characterization of deprenyl-N-oxide and other deprenyl metabolites by capillary electrophoresis using a dual cyclodextrin system in rat urine.

Journal: Electrophoresis 20030801

Title: Selegiline in the treatment of attention deficit hyperactivity disorder in children: a double blind and randomized trial.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20030801

Title: Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats.

Journal: Brain research 20030627

Title: Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons.

Journal: Antioxidants & redox signaling 20030601

Title: An HPLC tracing of the enhancer regulation in selected discrete brain areas of food-deprived rats.

Journal: Life sciences 20030509

Title: Enhancer substances: selegiline and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes.

Journal: Life sciences 20030502

Title: Neuroprotection by deprenyl and other propargylamines: glyceraldehyde-3-phosphate dehydrogenase rather than monoamine oxidase B.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030501

Title: Environmental influence on recovery after brain lesions--experimental and clinical data.

Journal: Journal of rehabilitation medicine 20030501

Title: Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons.

Journal: Journal of neurocytology 20030501

Title: A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (selegiline), alpha-tocopherol was ineffective in the DATATOP study.

Journal: Life sciences 20030425

Title: Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine.

Journal: Synapse (New York, N.Y.) 20030401

Title: Quantitative analysis of desmethylselegiline, methamphetamine, and amphetamine in hair and plasma from Parkinson patients on long-term selegiline medication.

Journal: Journal of analytical toxicology 20030401

Title: Selegiline in the treatment of Parkinson's disease: its impact on orthostatic hypotension.

Journal: Parkinsonism & related disorders 20030301

Title: Safety of selegiline with cold medications.

Journal: The Annals of pharmacotherapy 20030301

Title: [Biomedical imaging in pharmacology with nuclear medical imaging methodologies: positron emission tomography (PET) and single photon emission computed tomography (SPECT)].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20030301

Title: Monoamine oxidase inhibitors--is it time to up the TEMPO?

Journal: The Lancet. Neurology 20030301

Title: Selegiline attenuates cardiac oxidative stress and apoptosis in heart failure: association with improvement of cardiac function.

Journal: European journal of pharmacology 20030214

Title: l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030201

Title: A double-blind, placebo-controlled trial of the safety and efficacy of selegiline transdermal system without dietary restrictions in patients with major depressive disorder.

Journal: The Journal of clinical psychiatry 20030201

Title: The relevance of preclinical studies for the treatment of Parkinson's disease.

Journal: Journal of neurology 20030201

Title: A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation.

Journal: Biological psychiatry 20030115

Title: Protective effects of selegiline and desmethylselegiline against N-methyl-D-aspartate-induced rat retinal damage.

Journal: European journal of pharmacology 20030101

Title: Evidence for dopamine-derived hydroxyl radical formation in the nigrostriatal system in response to axotomy.

Journal: Free radical biology & medicine 20030101

Title: Selegiline for Alzheimer's disease.

Journal: The Cochrane database of systematic reviews 20030101

Title: In vivo imaging of brain dopaminergic neurotransmission system in small animals with high-resolution single photon emission computed tomography.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030101

Title: Selegiline-transdermal--Somerset: Emsam.

Journal: Drugs in R&D 20030101

Title: Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion.

Journal: Neurobiology of aging 20030101

Title: Daily transdermal administration of selegiline to guinea-pigs preferentially inhibits monoamine oxidase activity in brain when compared with intestinal and hepatic tissues.

Journal: The Journal of pharmacy and pharmacology 20030101

Title: Neuroprotection for Parkinson's disease: prospects and promises.

Journal: Annals of neurology 20030101

Title: Lack of influence of the apolipoprotein E genotype on the outcome of selegiline treatment in Alzheimer's disease.

Journal: Dementia and geriatric cognitive disorders 20030101

Title: Neurostimulatory and antioxidative effects of L-deprenyl in aged rat brain regions.

Journal: Biogerontology 20030101

Title: Clinical pharmacokinetics of cabergoline.

Journal: Clinical pharmacokinetics 20030101

Title: Selegiline in the treatment of sexual dysfunction in schizophrenic patients maintained on neuroleptics: a pilot study.

Journal: Clinical neuropharmacology 20030101

Title: Noncholinergic treatment options for Alzheimer's disease.

Journal: The Journal of clinical psychiatry 20030101

Title: Arguments for the use of dopamine receptor agonists in clinical and preclinical Parkinson's disease.

Journal: Journal of neural transmission. Supplementum 20030101

Title: Antioxidant properties of newly synthesized N-propargylamine derivatives of nitroxyl: a comparison with deprenyl.

Journal: Polish journal of pharmacology 20030101

Title: Neuroprotective effect of deprenyl in sensory neurons of axotomized dorsal root ganglion.

Journal: Clinical neuropharmacology 20030101

Title: [Mild cognitive impairment].

Journal: Ryoikibetsu shokogun shirizu 20030101

Title: [Effect of a new antiparkinsonian drug himantane on monoamine oxidase activity].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20030101

Title: Medical treatment of hyperadrenocorticism in the dog.

Journal: Australian veterinary journal 20030101

Title: Detection, quantification, metabolism, and behavioral effects of selegiline in horses.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20030101

Title: Selegiline enhances erectile activity induced by dopamine injection in the paraventricular nucleus of the hypothalamus in anesthetized rats.

Journal: International journal of impotence research 20021201

Title: [Long-term treatment of Parkinson's disease patients with selegiline hydrochloride (FPF 1100): outcome of 5-year treatment].

Journal: No to shinkei = Brain and nerve 20021201

Title: Recent advances in Parkinson's disease.

Journal: Ideggyogyaszati szemle 20021120

Title: Transdermal selegiline in major depression: a double-blind, placebo-controlled, parallel-group study in outpatients.

Journal: The American journal of psychiatry 20021101

Title: Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits.

Journal: Neuropharmacology 20021101

Title: Effects of short- and long-term (--)-deprenyl administration on mRNA for copper, zinc- and manganese-superoxide dismutase and glutathione peroxidase in rat brain.

Journal: Brain research 20021025

Title: PET imaging of monoamine oxidase B in peripheral organs in humans.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021001

Title: Quantitative analysis of selegiline and three metabolites (N-desmethylselegiline, methamphetamine, and amphetamine) in human plasma by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.

Journal: Journal of analytical toxicology 20021001

Title: Practical importance of neuroprotection in Parkinson's disease.

Journal: Journal of neurology 20021001

Title: 1-(Benzofuran-2-yl)-2-(3,3,3-trifluoropropyl)aminopentane HCl, 3-F-BPAP, antagonizes the enhancer effect of (-)-BPAP in the shuttle box and leaves the effect of (-)-deprenyl unchanged.

Journal: Life sciences 20020913

Title: Effects of selegiline (L-deprenyl) during smoking and short-term abstinence.

Journal: Psychopharmacology 20020901

Title: Urinary excretion of selegiline N-oxide, a new indicator for selegiline administration in man.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20020901

Title: Selegiline: a second look. Six years later: too risky in Parkinson's disease.

Journal: Prescrire international 20020801

Title: Selegiline transdermal system Somerset.

Journal: Current opinion in investigational drugs (London, England : 2000) 20020801

Title: Effects of (-)deprenyl (selegiline) on acetylcholinesterase and Na(+),K(+)-ATPase activities in adult rat whole brain.

Journal: Pharmacological research 20020801

Title: Treatment of an acromegalic cat with the dopamine agonist L-deprenyl.

Journal: Australian veterinary journal 20020801

Title: [The usefulness of dopaminergic drugs in traumatic brain injury].

Journal: Revista de neurologia 20020801

Title: Neurological effects of psychopharmacological agents.

Journal: Seminars in clinical neuropsychiatry 20020701

Title: Effect of concomitant hormone replacement therapy containing estradiol and levonorgestrel on the pharmacokinetics of selegiline.

Journal: European journal of clinical pharmacology 20020701

Title: Smoking cessation and panic attacks: a report of 2 cases.

Journal: The Journal of clinical psychiatry 20020701

Title: Electroencephalographic activation by tacrine, deprenyl, and quipazine: cholinergic vs. non-cholinergic contributions.

Journal: European journal of pharmacology 20020628

Title: Effects of selegiline, phenylpropanolamine, or a combination of both on physiologic and behavioral variables in healthy dogs.

Journal: American journal of veterinary research 20020601

Title: Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results.

Journal: Journal of occupational and environmental medicine 20020501

Title: (-)-Deprenyl fails to promote axonal regeneration of retinal ganglion cells in vitro and in vivo.

Journal: Cell and tissue research 20020501

Title: The effect of deprenyl washout in patients with long-standing Parkinson's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020501

Title: Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial.

Journal: Annals of neurology 20020501

Title: Modulation of neuroendocrine--immune signaling by L-deprenyl and L-desmethyldeprenyl in aging and mammary cancer.

Journal: Mechanisms of ageing and development 20020430

Title: Why (--)deprenyl prolongs survivals of experimental animals: increase of anti-oxidant enzymes in brain and other body tissues as well as mobilization of various humoral factors may lead to systemic anti-aging effects.

Journal: Mechanisms of ageing and development 20020430

Title: Pharmacological interventions in aging and age-associated disorders: potentials of propargylamines for human use.

Journal: Annals of the New York Academy of Sciences 20020401

Title: Effects of selegiline on fronto-temporal dementia: a neuropsychological evaluation.

Journal: International journal of geriatric psychiatry 20020401

Title: [Serotonin syndrome: report of a fatal case and review of the literature].

Journal: Revista clinica espanola 20020401

Title: [The evolution of use of anti-Parkinson drugs in Spain].

Journal: Revista de neurologia 20020401

Title: Inhibition of human LDL oxidation by the neuroprotective drug l-deprenyl.

Journal: Neurological research 20020301

Title: Placebo-associated improvements in motor function: comparison of subjective and objective sections of the UPDRS in early Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020301

Title: Treatment of periodic limb movements in sleep with selegiline HCl.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020301

Title: Effect of R-(-)-deprenyl and harmaline on dopamine- and peroxynitrite-induced membrane permeability transition in brain mitochondria.

Journal: Neurochemical research 20020301

Title: Rat striatal monoamine oxidase-B inhibition by l-deprenyl and rasagiline: its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease.

Journal: Parkinsonism & related disorders 20020301

Title: Neuroprotective actions of selegiline.

Journal: Journal of neuroscience research 20020201

Title: The effect of selegiline in the treatment of people with Alzheimer's disease: a meta-analysis of published trials.

Journal: International journal of geriatric psychiatry 20020201

Title: Antiapoptotic effect of (-)-deprenyl in rat kidney after ischemia-reperfusion.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20020201

Title: Deprenyl protects from MPTP-induced Parkinson-like syndrome and glutathione oxidation in rat striatum.

Journal: Toxicology 20020125

Title: The influence of metabolism on the MAO-B inhibitory potency of selegiline.

Journal: Current medicinal chemistry 20020101

Title: Effect of repeated treatment with high doses of selegiline on behaviour, striatal dopaminergic transmission and tyrosine hydroxylase mRNA levels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020101

Title: Nitecapone and selegiline as effective adjuncts to L-DOPA in reserpine-induced catatonia in mice.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: Morphometric evaluation of the neuroprotective effect of deprenyl on postaxotomic motor neuron losses.

Journal: Clinical neuropharmacology 20020101

Title: [Study of the tissue and subcellular distribution of isatin-binding proteins with optical biosensor].

Journal: Voprosy meditsinskoi khimii 20020101

Title: Reversible transvestic fetishism in a man with Parkinson's disease treated with selegiline.

Journal: Clinical neuropharmacology 20020101

Title: MAO-B inhibitors for the treatment of Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020101

Title: [Monoamine oxidase inhibitors: prospects for the use in clinical practice].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

Title: The multiple actions of selegiline.

Journal: Proceedings of the Western Pharmacology Society 20020101

Title: Monoamine oxidase inhibitors: a new generation.

Journal: Psychopharmacology bulletin 20020101

Title: Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.

Journal: The Cochrane database of systematic reviews 20020101

Title: [Effectiveness and tolerability of selegiline in the treatment of pathological cerebral involutions].

Journal: La Clinica terapeutica 20020101

Title: Zonisamide has beneficial effects on Parkinson's disease patients.

Journal: Neuroscience research 20011201

Title: Investigating potential anxiolytic, antidepressant and memory enhancing activity of deprenyl.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201

Title: Ten-year follow-up of three different initial treatments in de-novo PD: a randomized trial.

Journal: Neurology 20011113

Title: Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice.

Journal: Brain research 20011102

Title: (-)-D-Deprenyl attenuates apoptosis in experimental brain ischaemia.

Journal: European journal of pharmacology 20011102

Title: CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011101

Title: The effects of oral selegiline hydrochloride on learning and training in the dog: a psychobiological interpretation.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20011101

Title: Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.

Journal: Pharmacology & toxicology 20011101

Title: Future of neuroprotection in Parkinson's disease.

Journal: Parkinsonism & related disorders 20011001

Title: Incorporation of selegiline metabolites into hair after oral selegiline intake.

Journal: Journal of analytical toxicology 20011001

Title: Medical treatment of canine pituitary-dependent hyperadrenocorticism (Cushing's disease).

Journal: The Veterinary clinics of North America. Small animal practice 20010901

Title: Simultaneous determination of selegiline-N-oxide, a new indicator for selegiline administration, and other metabolites in urine by high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010805

Title: Inhibition of rat liver microsomal CYP1A2 and CYP2B1 activity by N-(2-heptyl)-N-methyl-propargylamine and by N-(2-heptyl)-propargylamine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010801

Title: [Parkinson's disease].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010801

Title: Changes in vascular alpha 1- and alpha 2-adrenoceptor responsiveness by selegiline treatment.

Journal: Fundamental & clinical pharmacology 20010801

Title: Selegiline and mortality in subjects with Parkinson's disease: a longitudinal community study.

Journal: Neurology 20010724

Title: Selegiline and mortality in subjects with Parkinson's disease: a longitudinal community study.

Journal: Neurology 20010724

Title: Current advances in Parkinson's disease.

Journal: Trends in neurosciences 20010701

Title: Freezing of gait in PD: prospective assessment in the DATATOP cohort.

Journal: Neurology 20010626

Title: Oxygen inhalation enhances striatal dopamine metabolism and monoamineoxidase enzyme inhibition prevents it: a microdialysis study.

Journal: European journal of pharmacology 20010622

Title: Advances in managing Parkinson's disease.

Journal: Hospital practice (1995) 20010615

Title: PET with 11C-deuterium-deprenyl and 18F-FDG in focal epilepsy.

Journal: Acta neurologica Scandinavica 20010601

Title: The frissonnant mutant mouse, a model of dopamino-sensitive, inherited motor syndrome.

Journal: Neurobiology of disease 20010601

Title: Inhibition of MAO-A activity enhances behavioural activity of rats assessed using water maze and open arena tasks.

Journal: Pharmacology & toxicology 20010601

Title: Rescue of dying neurons by (R)-deprenyl in the MPTP-mouse model of Parkinson's disease does not include restoration of neostriatal dopamine.

Journal: Annals of the New York Academy of Sciences 20010601

Title: Paroxysmal hypertensive crises induced by selegiline in a patient with Parkinson's disease.

Journal: Journal of neurology 20010601

Title: [Parkinson patients. Normal life expectancy with selegiline?].

Journal: MMW Fortschritte der Medizin 20010528

Title: Evidence that L-deprenyl treatment for one week does not inhibit MAO A or the dopamine transporter in the human brain.

Journal: Life sciences 20010504

Title: Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2-propylaminopentane, ((-)BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain.

Journal: Bioorganic & medicinal chemistry 20010501

Title: CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline.

Journal: European journal of clinical pharmacology 20010501

Title: Monoamine oxidase assays.

Journal: Current protocols in pharmacology 20010501

Title: L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: a microdialysis study in rats.

Journal: Neuroscience letters 20010420

Title: Selective inhibition of MAO-B through chronic low-dose (R)-deprenyl treatment in C57BL/6 mice has no effect on basal neostriatal dopamine levels.

Journal: Experimental neurology 20010401

Title: Attenuation of paraquat-induced dopaminergic toxicity on the substantia nigra by (-)-deprenyl in vivo.

Journal: Toxicology and applied pharmacology 20010401

Title: Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole.

Journal: European journal of clinical pharmacology 20010401

Title: Deprenyl stimulates the efflux of monoamines from the rat hypothalamus in vitro.

Journal: Brain research bulletin 20010401

Title: Do antioxidant strategies work against aging and age-associated disorders? Propargylamines: a possible antioxidant strategy.

Journal: Annals of the New York Academy of Sciences 20010401

Title: Substrate and inhibitor specificities for human monoamine oxidase A and B are influenced by a single amino acid.

Journal: The Journal of biological chemistry 20010330

Title: L-dopa and selegiline for tyrosine hydroxylase deficiency.

Journal: The Journal of pediatrics 20010301

Title: Parkinson's disease therapy: treatment of early and late disease.

Journal: Chinese medical journal 20010301

Title: Eldepryl prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigral neuronal apoptosis in mice.

Journal: Chinese medical journal 20010301

Title: SKF-38393, a dopamine receptor agonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity.

Journal: Brain research 20010223

Title: Selective inhibition of amine oxidases differently potentiate the hypophagic effect of benzylamine in mice.

Journal: European journal of pharmacology 20010209

Title: Selegiline combined with enriched-environment housing attenuates spatial learning deficits following focal cerebral ischemia in rats.

Journal: Experimental neurology 20010201

Title: The economic consequences of a drug-drug interaction.

Journal: Journal of clinical psychopharmacology 20010201

Title: Enhancement of central nervous system pathology in early simian immunodeficiency virus infection by dopaminergic drugs.

Journal: Acta neuropathologica 20010201

Title: Possible applications for dopaminergic agents following traumatic brain injury: part 2.

Journal: The Journal of head trauma rehabilitation 20010201

Title: Selegiline completely restores choline acetyltransferase activity deficits in simian immunodeficiency infection.

Journal: European journal of pharmacology 20010105

Title: Different sensitivity of mitochondrial and cytosolic monoamine oxidases to in vivo but not in vitro inhibition by specific irreversible inhibitors.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: Anti-apoptotic and apoptotic action of (-)-deprenyl and its metabolites.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Freezing of gait in patients with advanced Parkinson's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Long-term persistence of symptomatic effect of selegiline in Parkinson's disease. A two-months placebo-controlled withdrawal study.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Biphasic effects of selegiline on striatal dopamine: lack of effect on methamphetamine-induced dopamine depletion.

Journal: Neurochemical research 20010101

Title: [Current strategies of pathogenetic therapy of Alzheimer's disease].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101

Title: Effect of longevity treatment with (-)deprenyl on lifespan and sexual behavior in female rats.

Journal: Neurobiology (Budapest, Hungary) 20010101

Title: Antiaging compounds: (-)deprenyl (selegeline) and (-)1-(benzofuran-2-yl)-2-propylaminopentane, [(-)BPAP], a selective highly potent enhancer of the impulse propagation mediated release of catecholamine and serotonin in the brain.

Journal: CNS drug reviews 20010101

Title: Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: [The effect of selegiline and vitamin E in the treatment of ALS: an open randomized clinical trials].

Journal: Neurologia i neurochirurgia polska 20010101

Title: The effect of low oral doses of (-)-deprenyl and its metabolites on DSP-4 toxicity.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Pharmacological options for the treatment of Tourette's disorder.

Journal: Drugs 20010101

Title: Selegiline treatment facilitates recovery after stroke.

Journal: Neurorehabilitation and neural repair 20010101

Title: A noncomparative open-label study evaluating the effect of selegiline hydrochloride in a clinical setting.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20010101

Title: [Dopaminergic agonists in the treatment of Parkinson's disease].

Journal: Revue medicale de Bruxelles 20001201

Title: Antioxidant activity of the monoamine oxidase B inhibitor lazabemide.

Journal: Biochemical pharmacology 20000901

Title: A hypertensive reaction induced by concurrent use of selegiline and dopamine.

Journal: The Annals of pharmacotherapy 20000901

Title: Adverse drug reactions to selegiline: a review of the French pharmacovigilance database.

Journal: Clinical neuropharmacology 20000101

Title: The novel type B MAO inhibitor PF9601N enhances the duration of L-DOPA-induced contralateral turning in 6-hydroxydopamine lesioned rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20000101

Title: Deterioration of parkinsonian symptoms following treatment of dopaminergic hallucinosis with olanzapine.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 19991001

Title: Effect of selegiline on cognitive functions in Parkinson's disease.

Journal: The Journal of the Association of Physicians of India 19990801

Title: Selegiline effects on cocaine-induced changes in medial temporal lobe metabolism and subjective ratings of euphoria.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19990601

Title: Selegiline-induced postural hypotension in Parkinson's disease: a longitudinal study on the effects of drug withdrawal.

Journal: Movement disorders : official journal of the Movement Disorder Society 19990301

Title: Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline).

Journal: Journal of neural transmission. Supplementum 19980101

Title: Experience with tranylcypromine in early Parkinson's disease.

Journal: Journal of neural transmission. Supplementum 19980101

Title: Autonomic effects of selegiline: possible cardiovascular toxicity in Parkinson's disease.

Journal: Journal of neurology, neurosurgery, and psychiatry 19970801

Title: The anticonvulsant effect of deprenyl on pentylenetetrazol-induced seizures in Lewis rats.

Journal: The International journal of neuroscience 19970801

Title: Venlafaxine, monoamine oxidase inhibitors, and the serotonin syndrome.

Journal: Journal of clinical psychopharmacology 19970201

Title: Absence of acute cocaine interactions with the MAO-B inhibitor selegiline.

Journal: Drug and alcohol dependence 19950701

Title: Pharmacokinetic aspects of l-deprenyl (selegiline) and its metabolites.

Journal: Clinical pharmacology and therapeutics 19941201

Title: The MAO-B inhibitor deprenyl, but not the MAO-A inhibitor clorgyline, potentiates the neurotoxicity of p-chloroamphetamine.

Journal: Brain research 19940711

Title: Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease: the degree and reversibility of human brain MAO B inhibition by Ro 19 6327.

Journal: Neurology 19931001

Title: End-of-dose dystonia in Parkinson's disease.

Journal: Neurology 19931001

Title: Deprenyl in attention deficit associated with Tourette's syndrome.

Journal: Archives of neurology 19930301

Title: Pseudophaeochromocytoma in parkinsonian patient treated with fluoxetine plus selegiline.

Journal: Lancet (London, England) 19930227

Title: Selegiline and manic behavior in Parkinson's disease.

Journal: Archives of neurology 19921201

Title: In vivo and in vitro pharmacologic profile of two new irreversible MAO-B inhibitors: MDL 72,974A and fluorodeprenyl.

Journal: Annals of the New York Academy of Sciences 19920511

Title: Deprenyl effects on levodopa pharmacodynamics, mood, and free radical scavenging.

Journal: Neurology 19920301

Title: Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons.

Journal: The Journal of pharmacology and experimental therapeutics 19911101

Title: Improvement of cognitive function by MAO-B inhibitor L-deprenyl in aged rats.

Journal: Pharmacology, biochemistry, and behavior 19910601

Title: A review of the pharmacology of selegiline.

Journal: Acta neurologica Scandinavica. Supplementum 19910101

Title: Evaluation of the effects of inhibition of monoamine oxidase and senescence on methamphetamine-induced neuronal damage.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 19910101

Title: Ro 19-6327, a reversible and highly selective monoamine, oxidase B inhibitor: a novel tool to explore the MAO-B function in humans.

Journal: Advances in neurology 19900101

Title: The effect of deprenyl (selegiline) on the natural history of Parkinson's disease.

Journal: Science (New York, N.Y.) 19890804

Title: A possible L-deprenyl induced hypertensive reaction.

Journal: Journal of clinical psychopharmacology 19890801

Title: Potentiation of central effects of L-dopa by an inhibitor of catechol-O-methyltransferase.

Journal: Journal of neural transmission 19870101

Title: SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.

Journal: The Journal of pharmacology and experimental therapeutics 19870101

Title: Pharmacokinetic aspects of deprenyl effects.

Journal: Polish journal of pharmacology and pharmacy 19840101

Title: Brain monoamine oxidase in suckling rabbits treated with organophosphorus compound. I. Acute intoxication.

Journal: Acta physiologica Polonica 19840101

Title: Deprenyl (selegiline) in combination treatment of Parkinson's disease.

Journal: Acta neurologica Scandinavica. Supplementum 19830101

Title: The nature of the inhibition of rat liver monoamine oxidase types A and B by the acetylenic inhibitors clorgyline, l-deprenyl and pargyline.

Journal: Biochemical pharmacology 19821115

Title: Inhibition of rabbit liver monoamine oxidase by nitro aromatic compounds.

Journal: Biochemical pharmacology 19820815

Title: Oscillations in performance in levodopa-treated parkinsonians: treatment with bromocriptine and L-deprenyl.

Journal: Clinical and experimental neurology 19790101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:14611-52-0 Molecular Formula|14611-52-0 MDL|14611-52-0 SMILES|14611-52-0 Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, hydrochloride (1:1), (αR)-
Catalog No.: AA001DMJ
14611-52-0,MFCD00069299
14611-52-0 | Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, hydrochloride (1:1), (αR)-
Pack Size: 100mg
Purity: ≥98%
in stock
$46.00 $32.00
Pack Size: 250mg
Purity: ≥98%
in stock
$86.00 $60.00
Pack Size: 500mg
Purity: ≥98%
in stock
$133.00 $93.00
Pack Size: 1g
Purity: ≥98%
in stock
$199.00 $139.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA001DMJ
Chemical Name: Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, hydrochloride (1:1), (αR)-
CAS Number: 14611-52-0
Molecular Formula: C13H18ClN
Molecular Weight: 223.7417
MDL Number: MFCD00069299
SMILES: C[C@@H](N(CC#C)C)Cc1ccccc1.Cl
Properties
Complexity: 195  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 15  
Hydrogen Bond Acceptor Count: 1  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 4  
Literature fold

Title: Inhibition of monoamine oxidase-B by selegiline reduces cigarette smoke-induced oxidative stress and inflammation in airway epithelial cells.

Journal: Toxicology letters20170215

Title: Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction.

Journal: Chemico-biological interactions20150325

Title: Deuterium-substituted L-DOPA displays increased behavioral potency and dopamine output in an animal model of Parkinson's disease: comparison with the effects produced by L-DOPA and an MAO-B inhibitor.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20150201

Title: Deprenyl enhances the teratogenicity of hydroxyurea in organogenesis stage mouse embryos.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20130801

Title: Comparison of the cutaneous iontophoretic delivery of rasagiline and selegiline across porcine and human skin in vitro.

Journal: International journal of pharmaceutics20121115

Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuroblastic apoptosis in the subventricular zone is caused by 1-methy-4-phenylpiridinium (MPP(+)) converted from MPTP through MAO-B.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie20121101

Title: Retention rate of selegiline in early Parkinson's disease: a retrospective survey.

Journal: International journal of clinical practice20121001

Title: Involvement of monoamine oxidase B on models of postoperative and neuropathic pain in mice.

Journal: European journal of pharmacology20120905

Title: Cerebral blood flow and freezing of gait in Parkinson's disease.

Journal: Acta neurologica Scandinavica20120901

Title: Pramipexole-related chronic lower limb oedema in a patient with Parkinson's disease.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia20120901

Title: Modulations of brain amines and dopaminergic behavior by a novel, reversible and selective MAO-B inhibitor.

Journal: Brain research20120827

Title: Disease progress and response to treatment as predictors of survival, disability, cognitive impairment and depression in Parkinson's disease.

Journal: British journal of clinical pharmacology20120801

Title: Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors.

Journal: Angewandte Chemie (International ed. in English)20120709

Title: AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH.

Journal: Biochemical and biophysical research communications20120622

Title: Subthalamic deep brain stimulation at individualized frequencies for Parkinson disease.

Journal: Neurology20120612

Title: Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation.

Journal: Biochemistry. Biokhimiia20120601

Title: Cardiovascular baroreceptor activity and selective inhibition of monoamine oxidase.

Journal: European journal of pharmacology20120515

Title: Basic cell physiological activities (cell adhesion, chemotaxis and proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20120501

Title: Safety of selegiline transdermal system in clinical practice: analysis of adverse events from postmarketing exposures.

Journal: The Journal of clinical psychiatry20120501

Title: Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20120401

Title: In vitro-in vivo correlation for intrinsic clearance for CP-409,092 and sumatriptan: a case study to predict the in vivo clearance for compounds metabolized by monoamine oxidase.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20120401

Title: In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand.

Journal: Synapse (New York, N.Y.)20120401

Title: 8-Substituted 3-arylcoumarins as potent and selective MAO-B inhibitors: synthesis, pharmacological evaluation, and docking studies.

Journal: ChemMedChem20120305

Title: Selegiline transdermal system (STS) as an aid for smoking cessation.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco20120301

Title: Induction of adipose-derived stem cell into motoneuron-like cells using selegiline as preinducer.

Journal: Brain research20120227

Title: Tyrosine hydroxylase deficiency in Taiwanese infants.

Journal: Pediatric neurology20120201

Title: The effect of selegiline on total scavenger capacity and liver fat content: a preliminary study in an animal model.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20120101

Title: Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20120101

Title: Selegiline: a reappraisal of its role in Parkinson disease.

Journal: Clinical neuropharmacology20120101

Title: Deprenyl prevents MPP(+)-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk.

Journal: Toxicology20111218

Title: In vivo imaging of astrocytosis in Alzheimer's disease: an ¹¹C-L-deuteriodeprenyl and PIB PET study.

Journal: European journal of nuclear medicine and molecular imaging20111201

Title: PET imaging for attention deficit preclinical drug testing in neurofibromatosis-1 mice.

Journal: Experimental neurology20111201

Title: Predicting successful 24-hr quit attempt in a smoking cessation intervention.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco20111101

Title: Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report.

Journal: Pharmacopsychiatry20111101

Title: Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).

Journal: Journal of medicinal chemistry20111027

Title: Trans-differentiation of the adipose tissue-derived stem cells into neuron-like cells expressing neurotrophins by selegiline.

Journal: Iranian biomedical journal20111001

Title: Selegiline-functionalized, PEGylated poly(alkyl cyanoacrylate) nanoparticles: Investigation of interaction with amyloid-β peptide and surface reorganization.

Journal: International journal of pharmaceutics20110920

Title: Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells.

Journal: In vitro cellular & developmental biology. Animal20110901

Title: Transdermal delivery of selegiline from alginate-Pluronic composite thermogels.

Journal: International journal of pharmaceutics20110830

Title: CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease.

Journal: Brain research20110823

Title: Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20110801

Title: MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins.

Journal: Bioorganic & medicinal chemistry letters20110715

Title: The relationship between depression and regional cerebral blood flow in Parkinson's disease and the effect of selegiline treatment.

Journal: Acta neurologica Scandinavica20110701

Title: Differences in smoking expectancies in smokers with and without a history of major depression.

Journal: Addictive behaviors20110401

Title: Selegiline use is associated with a slower progression in early Parkinson's disease as evaluated by Hoehn and Yahr Stage transition times.

Journal: Parkinsonism & related disorders20110301

Title: Expanding phenotype and clinical analysis of tyrosine hydroxylase deficiency.

Journal: Journal of child neurology20110201

Title: Tolerability and efficacy of switching from oral selegiline to Zydis selegiline in patients with Parkinson's disease.

Journal: Parkinsonism & related disorders20110201

Title: MAO inhibitors.

Journal: Cleveland Clinic journal of medicine20110201

Title: The anti-Parkinsonian drug selegiline delays the nucleation phase of α-synuclein aggregation leading to the formation of nontoxic species.

Journal: Journal of molecular biology20110107

Title: Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography.

Journal: Neurochemistry international20110101

Title: Selegiline and rasagiline: twins or distant cousins?

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists20110101

Title: Pharmacotherapy for late-life depression.

Journal: The Journal of clinical psychiatry20110101

Title: Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro.

Journal: BMC pharmacology20110101

Title: Elevated [11C]-D-deprenyl uptake in chronic Whiplash Associated Disorder suggests persistent musculoskeletal inflammation.

Journal: PloS one20110101

Title: Serum cholesterol and the progression of Parkinson's disease: results from DATATOP.

Journal: PloS one20110101

Title: The pharmacology of selegiline.

Journal: International review of neurobiology20110101

Title: Selective inhibitors of monoamine oxidase type B and the 'cheese effect'.

Journal: International review of neurobiology20110101

Title: Supplementation of deprenyl attenuates age associated alterations in rat cerebellum.

Journal: Molecular biology reports20101201

Title: Clinical pharmacology tyramine challenge study to determine the selectivity of the monoamine oxidase type B (MAO-B) inhibitor rasagiline.

Journal: Journal of clinical pharmacology20101201

Title: R-deprenyl: pharmacological spectrum of its activity.

Journal: Neurochemical research20101201

Title: MAO inhibitors: risks, benefits, and lore.

Journal: Cleveland Clinic journal of medicine20101201

Title: Ring opening of pymisyl-protected aziridines with organocuprates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20101102

Title: Transdermal iontophoretic delivery of selegiline hydrochloride, in vitro.

Journal: Journal of drug targeting20101101

Title: Rasagiline: a novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity.

Journal: Progress in neurobiology20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Orthostatic hypotension: a non-motor complication assessment in 82 patients with idiopathic Parkinson's disease in Phramongkutklao Hospital.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet20101101

Title: The fabulous neuroprotection of selegiline: memoir and prospectus.

Journal: Journal of child neurology20101001

Title: Clozapine for medication-related pathological gambling in Parkinson disease.

Journal: Movement disorders : official journal of the Movement Disorder Society20100915

Title: Age-related protective effect of deprenyl on changes in the levels of diagnostic marker enzymes and antioxidant defense enzymes activities in cerebellar tissue in Wistar rats.

Journal: Cell stress & chaperones20100901

Title: HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology20100901

Title: Changes in smoking expectancies in abstinent, reducing, and non-abstinent participants during a pharmacological trial for smoking cessation.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco20100901

Title: Failure to improve cigarette smoking abstinence with transdermal selegiline + cognitive behavior therapy.

Journal: Addiction (Abingdon, England)20100901

Title: [The feasibility of synthetic enhancer substances for preventive nanotherapy].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology20100901

Title: Slowing the decline.

Journal: Nature20100826

Title: Cytoprotective effect of (-)-deprenyl, (-)desmethyl-deprenyl and (-)deprenyl-N-oxide on glutathione depleted A-2058 melanoma cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20100601

Title: A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage.

Journal: Biological psychiatry20100501

Title: Marked improvement in Segawa syndrome after L-dopa and selegiline treatment.

Journal: Pediatric neurology20100501

Title: [General anaesthesia for neurological diseases].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS20100501

Title: Regulation of brain-derived neurotrophic factor (BDNF) and cerebral dopamine neurotrophic factor (CDNF) by anti-parkinsonian drug therapy in vivo.

Journal: Cellular and molecular neurobiology20100401

Title: Manganese neurotoxic time course is not influenced by L-deprenyl systemic treatment: influence of L-deprenyl in manganese neurotoxic time course.

Journal: Brain research20100304

Title: Selegiline is an efficient and potent inducer for bone marrow stromal cell differentiation into neuronal phenotype.

Journal: Neurological research20100301

Title: A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers.

Journal: Drug and alcohol dependence20100301

Title: [On the role of MAO B inhibitors and NMDA antagonists in the therapy of Parkinson's disease].

Journal: Fortschritte der Neurologie-Psychiatrie20100301

Title: Cognitive aspects of congenital learned helplessness and its reversal by the monoamine oxidase (MAO)-B inhibitor deprenyl.

Journal: Neurobiology of learning and memory20100201

Title: (-)-Deprenyl inhibits vascular hyperpermeability after hemorrhagic shock.

Journal: Shock (Augusta, Ga.)20100101

Title: Orally disintegrating selegiline in Parkinson patients with dopamine agonist-related adverse effects.

Journal: Clinical neuropharmacology20100101

Title: Early addition of selegiline to L-Dopa treatment is beneficial for patients with Parkinson disease.

Journal: Clinical neuropharmacology20100101

Title: Frontotemporal dementia and pharmacologic interventions.

Journal: The Journal of neuropsychiatry and clinical neurosciences20100101

Title: Transdermal selegiline in patients receiving electroconvulsive therapy.

Journal: Psychosomatics20100101

Title: Electropharmacograms of rasagiline, its metabolite aminoindan and selegiline in the freely moving rat.

Journal: Neuropsychobiology20100101

Title: Zonisamide attenuates MPTP neurotoxicity in marmosets.

Journal: Journal of pharmacological sciences20100101

Title: A comparison of treatment thresholds in two large Parkinson's disease clinical trial cohorts.

Journal: Movement disorders : official journal of the Movement Disorder Society20091215

Title: Selegiline and oxidative stress in HIV-associated cognitive impairment.

Journal: Neurology20091208

Title: Acidic vesicles of the endo-exocytic pathways as targets for some anti-monoamine oxidase drugs.

Journal: Metabolic brain disease20091201

Title: [Severe apathy following head injury: improvement with Selegiline treatment].

Journal: Neuro-Chirurgie20091201

Title: [Slowing the age-induced decline of brain function with prophylactic use of (-)-deprenyl (Selegiline, Jumex). Current international view and conclusions 25 years after the Knoll's proposal].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology20091201

Title: Effect of deprenyl on free radical oxidation in rat brain during immobilization stress.

Journal: Bulletin of experimental biology and medicine20091201

Title: Incidence of and risk factors for cognitive impairment in an early Parkinson disease clinical trial cohort.

Journal: Neurology20091103

Title: Genomic and proteomic study to survey the mechanism of action of the anti-Parkinson's disease drug, rasagiline compared with selegiline, in the rat midbrain.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20091101

Title: Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease.

Journal: The Cochrane database of systematic reviews20091007

Title: Transdermal permeation of selegiline from hydrogel-membrane drug delivery systems.

Journal: International journal of pharmaceutics20091001

Title: (-)Deprenyl-N-oxide, a (-)deprenyl metabolite, is cytoprotective after hypoxic injury in PC12 cells, or after transient brain ischemia in gerbils.

Journal: Journal of the neurological sciences20090815

Title: Serotonin toxicity caused by moclobemide too soon after paroxetine-selegiline.

Journal: Journal of the Chinese Medical Association : JCMA20090801

Title: Selegiline shortage: Causes and costs of a generic drug shortage.

Journal: Neurology20090721

Title: Selegiline transdermal system: a novel treatment option for major depressive disorder.

Journal: Expert opinion on pharmacotherapy20090701

Title: A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.

Journal: Bioorganic & medicinal chemistry letters20090615

Title: Teasing apart drug treatments and individual symptoms in narcolepsy.

Journal: Sleep medicine20090601

Title: Short-term erythrosine B-induced inhibition of the brain regional serotonergic activity suppresses motor activity (exploratory behavior) of young adult mammals.

Journal: Pharmacology, biochemistry, and behavior20090601

Title: Involvement of protein trafficking in deprenyl-induced alpha-secretase activity regulation in PC12 cells.

Journal: European journal of pharmacology20090521

Title: Long-term administration of monoamine oxidase inhibitors alters the firing rate and pattern of dopamine neurons in the ventral tegmental area.

Journal: The international journal of neuropsychopharmacology20090501

Title: Assessment of MAO-B occupancy in the brain with PET and [11C]-L-deprenyl-D2: a dose-finding study with a novel MAO-B inhibitor, EVT 301.

Journal: Clinical pharmacology and therapeutics20090501

Title: Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP.

Journal: Journal of pharmacological sciences20090501

Title: MAO-B inhibitor know-how: back to the pharm.

Journal: Neurology20090414

Title: Hyperserotonergic phenotype after monoamine oxidase inhibition in larval zebrafish.

Journal: Journal of neurochemistry20090401

Title: Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.

Journal: Neurotoxicity research20090401

Title: 'Bad guys' among the antiparkinsonian drugs.

Journal: Psychiatria Danubina20090301

Title: Antioxidant and antiapoptotic activities of deprenyl and estradiol co-administration in aged rat kidney.

Journal: Acta biologica Hungarica20090301

Title: Neuroprotection by rasagiline in thiamine deficient rats.

Journal: Brain research20090223

Title: MPTP and MPP+ target specific aminergic cell populations in larval zebrafish.

Journal: Journal of neurochemistry20090201

Title: [Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings].

Journal: Ideggyogyaszati szemle20090130

Title: A case report of high-dose transdermal selegiline in the treatment of major depressive disorder.

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists20090101

Title: Investigation of oral selegiline and rasagiline administration on QT interval in conscious rabbits.

Journal: European review for medical and pharmacological sciences20090101

Title: A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.

Journal: BMC clinical pharmacology20090101

Title: (-)-Deprenyl inhibits thermal injury-induced apoptotic signaling and hyperpermeability in microvascular endothelial cells.

Journal: Journal of burn care & research : official publication of the American Burn Association20090101

Title: Serum prolactin as a tool for the follow-up of treated DHPR-deficient patients.

Journal: Journal of inherited metabolic disease20081201

Title: Antidepressant activity of curcumin: involvement of serotonin and dopamine system.

Journal: Psychopharmacology20081201

Title: 1-Methyl-4-phenyl-pyridinium ion-induced oxidative stress, c-Jun phosphorylation and DNA fragmentation factor-45 cleavage in SK-N-SH cells are averted by selegiline.

Journal: Neurochemistry international20081201

Title: The effect of short-term administration of (-)-deprenyl and isatin on the expressions of some genes in the mouse brain cortex.

Journal: Medical science monitor : international medical journal of experimental and clinical research20081201

Title: Neural progenitor cells are protected against MPTP by MAO-B inhibitors.

Journal: Neurotoxicology20081101

Title: Orally disintegrating selegiline for the treatment of Parkinson's disease.

Journal: Expert opinion on pharmacotherapy20081101

Title: Protective effects of deprenyl in transient cerebral ischemia in rats.

Journal: The Chinese journal of physiology20081031

Title: Apomorphine offers new insight into dopaminergic neuron vulnerability in mesencephalic cultures.

Journal: Neuropharmacology20081001

Title: Pharmacological treatment in moderate-to-severe Alzheimer's disease.

Journal: Expert opinion on pharmacotherapy20081001

Title: Detection of levorotatory methamphetamine and levorotatory amphetamine in urine after ingestion of an overdose of selegiline.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20081001

Title: [Rasagiline in daily clinical use. Results of a treatment study of Parkinson patients with a combination treatment].

Journal: Fortschritte der Neurologie-Psychiatrie20081001

Title: [Motor symptoms in Parkinson disease].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke20080925

Title: Fourteen-year final report of the randomized PDRG-UK trial comparing three initial treatments in PD.

Journal: Neurology20080812

Title: Synergistic effects of selegiline and donepezil on cognitive impairment induced by amyloid beta (25-35).

Journal: Behavioural brain research20080719

Title: Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration.

Journal: Journal of neurochemistry20080601

Title: Study of high deprenyl dose on the preimplantation embryo development and lymphocyte DNA in rat.

Journal: General physiology and biophysics20080601

Title: Selegiline reduces cisplatin-induced neuronal death in neuroblastoma cells.

Journal: Neurological research20080501

Title: The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B.

Journal: British journal of pharmacology20080501

Title: Predictors of deterioration in health-related quality of life in Parkinson's disease: results from the DATATOP trial.

Journal: Movement disorders : official journal of the Movement Disorder Society20080415

Title: Selegilin exerts antidepressant-like effects during the forced swim test in adrenocorticotropic hormone-treated rats.

Journal: Journal of pharmacological sciences20080401

Title: Optimization and validation of a dissolution test for selegiline hydrochloride tablets by a novel rapid HPLC assay using a monolithic stationary phase.

Journal: Journal of pharmaceutical and biomedical analysis20080313

Title: Efficacy of selegiline add on therapy to risperidone in the treatment of the negative symptoms of schizophrenia: a double-blind randomized placebo-controlled study.

Journal: Human psychopharmacology20080301

Title: Selegiline is a mechanism-based inactivator of CYP2A6 inhibiting nicotine metabolism in humans and mice.

Journal: The Journal of pharmacology and experimental therapeutics20080301

Title: Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.

Journal: Neurotoxicology20080301

Title: [A comparison of the pharmacology of (-)-deprenyl to N-methylpropargylamine-1-aminoindane (J-508) and rasagiline, the desmethyl-analogue of J-508].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology20080301

Title: [Role of apoptosis in the kidney after reperfusion].

Journal: Orvosi hetilap20080217

Title: Transdermal selegiline: new opportunity for managing depression.

Journal: The Journal of the American Osteopathic Association20080201

Title: [The use of Stalevo in Hungary for patients with Parkinson disease and its effect on the quality of life].

Journal: Ideggyogyaszati szemle20080130

Title: Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for 'in competition' anti-doping analysis.

Journal: Analytica chimica acta20080114

Title: The selegiline transdermal system in major depressive disorder: a systematic review of safety and tolerability.

Journal: Journal of affective disorders20080101

Title: Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20080101

Title: Neurobehavioral protection by single dose l-deprenyl against MPTP-induced parkinsonism in common marmosets.

Journal: Psychopharmacology20080101

Title: Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.

Journal: Journal of psychiatric practice20080101

Title: Effect of MAO-B inhibition against ischemia-induced oxidative stress in the rat brain. Comparison with a rational antioxidant.

Journal: Arzneimittel-Forschung20080101

Title: Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum.

Journal: Pharmacological reports : PR20080101

Title: Antagonistic effect of low deprenyl dose on the preimplantation embryo development in rat.

Journal: Bratislavske lekarske listy20080101

Title: Possible new antiaging strategies related to neuroendocrine-immune interactions.

Journal: Neuroimmunomodulation20080101

Title: Differential effects of selegiline on glucose synthesis in rabbit kidney-cortex tubules and hepatocytes. In vitro and in vivo studies.

Journal: Chemico-biological interactions20071215

Title: In vitro metabolism of the analgesic bicifadine in the mouse, rat, monkey, and human.

Journal: Drug metabolism and disposition: the biological fate of chemicals20071201

Title: Monoamine oxidase-B inhibition in the treatment of Parkinson's disease.

Journal: Pharmacotherapy20071201

Title: Symptoms of sexual dysfunction in patients treated for major depressive disorder: a meta-analysis comparing selegiline transdermal system and placebo using a patient-rated scale.

Journal: The Journal of clinical psychiatry20071201

Title: Deprenyl treatment attenuates long-term pre- and post-synaptic changes evoked by chronic methamphetamine.

Journal: European journal of pharmacology20071114

Title: Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats.

Journal: Psychopharmacology20071101

Title: Bystander effects of ionizing radiation can be modulated by signaling amines.

Journal: Environmental research20071001

Title: Pharmacokinetics and absolute bioavailability of selegiline following treatment of healthy subjects with the selegiline transdermal system (6 mg/24 h): a comparison with oral selegiline capsules.

Journal: Journal of clinical pharmacology20071001

Title: Zydis selegiline in the management of Parkinson's disease.

Journal: Expert opinion on pharmacotherapy20071001

Title: A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment.

Journal: Neurology20070925

Title: Lost in translation: again, another failed neuroprotection trial.

Journal: Neurology20070925

Title: Amine oxidases and their inhibitors: what can they tell us about neuroprotection and the development of drugs for neuropsychiatric disorders?

Journal: Journal of psychiatry & neuroscience : JPN20070901

Title: Comprehensive review of rasagiline, a second-generation monoamine oxidase inhibitor, for the treatment of Parkinson's disease.

Journal: Clinical therapeutics20070901

Title: A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: pharmacological validation with R-(-)-deprenyl.

Journal: Journal of neuroscience methods20070815

Title: Selegiline transdermal system: current awareness and promise.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20070815

Title: Evaluation of the potential for pharmacodynamic and pharmacokinetic drug interactions between selegiline transdermal system and two sympathomimetic agents (pseudoephedrine and phenylpropanolamine) in healthy volunteers.

Journal: Journal of clinical pharmacology20070801

Title: Low plasma uric acid level in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society20070615

Title: The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by two series of novel carbamates.

Journal: Molecular pharmacology20070601

Title: Antioxidant effects of selegiline in oxidative stress induced by iron neonatal treatment in rats.

Journal: Neurochemical research20070601

Title: Therapeutic advances in narcolepsy.

Journal: Sleep medicine20070601

Title: Treatment-resistant depression: response to low-dose transdermal but not oral selegiline.

Journal: Journal of clinical psychopharmacology20070601

Title: Transdermal selegiline.

Journal: Drugs of today (Barcelona, Spain : 1998)20070601

Title: Rasagiline as a therapy for Parkinson's disease (PD).

Journal: The American journal of geriatric pharmacotherapy20070601

Title: Anti-fibrillogenic and fibril-destabilizing activities of anti-Parkinsonian agents for alpha-synuclein fibrils in vitro.

Journal: Journal of neuroscience research20070515

Title: The role of selegiline in the treatment of negative symptoms associated with schizophrenia.

Journal: The Annals of pharmacotherapy20070501

Title: Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain.

Journal: Journal of ethnopharmacology20070420

Title: Evidence for astrocytosis in ALS demonstrated by [11C](L)-deprenyl-D2 PET.

Journal: Journal of the neurological sciences20070415

Title: Safety and efficacy of newly formulated selegiline orally disintegrating tablets as an adjunct to levodopa in the management of 'off' episodes in patients with Parkinson's disease.

Journal: Current medical research and opinion20070401

Title: Translating the evidence on atypical depression into clinical practice.

Journal: The Journal of clinical psychiatry20070401

Title: P450 phenotyping of the metabolism of selegiline to desmethylselegiline and methamphetamine.

Journal: Drug metabolism and pharmacokinetics20070401

Title: Involvement of cytochromes P450 2D6, 2B6 and 2C19 in the metabolism of (-)-deprenyl and N-methyl,N-propargylphenylethylamine.

Journal: Drug metabolism letters20070401

Title: Oxygen-glucose deprivation-induced changes in organotypic cultures of the rat hippocampus.

Journal: Ideggyogyaszati szemle20070330

Title: Metabolism of N-methyl, N-propargylphenylethylamine: studies with human liver microsomes and cDNA expressed cytochrome P450 (CYP) enzymes.

Journal: Cellular and molecular neurobiology20070301

Title: Selegiline and blood pressure in patients with Parkinson's disease.

Journal: Acta neurologica Scandinavica20070201

Title: Selegiline transdermal system: an examination of the potential for CYP450-dependent pharmacokinetic interactions with 3 psychotropic medications.

Journal: Journal of clinical pharmacology20070201

Title: Antioxidants and Alzheimer's disease: time to stop feeding vitamin E to dementia patients?

Journal: International psychogeriatrics20070201

Title: Separation of enantiomers of deprenyl with various CDs in CE and the effect of enantiomer migration order on enantiomeric impurity determination of selegiline in active ingredients and tablets.

Journal: Electrophoresis20070201

Title: Psychopharmacology column: why choose selegiline transdermal system for refractory depression?

Journal: Issues in mental health nursing20070201

Title: Management of sexual dysfunction due to antipsychotic drug therapy.

Journal: The Cochrane database of systematic reviews20070124

Title: Improvement of mouse brain mitochondrial function after deprenyl treatment.

Journal: Neuroscience20070119

Title: Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPalpha secretion by deprenyl.

Journal: Neurochemistry international20070101

Title: Chronic (-)-deprenyl administration attenuates dendritic developmental impairment induced by early social isolation in the rat.

Journal: Developmental neuroscience20070101

Title: Seligiline transdermal system in depression.

Journal: Expert opinion on pharmacotherapy20070101

Title: Effects of a tyramine-enriched meal on blood pressure response in healthy male volunteers treated with selegiline transdermal system 6 mg/24 hour.

Journal: CNS spectrums20070101

Title: Selegiline transdermal system: in the treatment of major depressive disorder.

Journal: Drugs20070101

Title: The effect of l-deprenyl on tissue mRNA expressions of NOS isoforms and NO levels in an experimental diabetes mellitus model.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20070101

Title: Selegiline transdermal system in major depressive disorder: profile report.

Journal: CNS drugs20070101

Title: Monamine oxidase inhibitors: current and emerging agents for Parkinson disease.

Journal: Clinical neuropharmacology20070101

Title: Suppression of apoptosis and oxidative stress by deprenyl and estradiol in aged rat liver.

Journal: Acta histochemica20070101

Title: Community and long-term care management of Parkinson's disease in the elderly: focus on monoamine oxidase type B inhibitors.

Journal: Drugs & aging20070101

Title: Selegiline orally disintegrating tablets in patients with Parkinson disease and 'wearing off' symptoms.

Journal: Clinical neuropharmacology20070101

Title: Placebo response in Parkinson trials using patient diaries: sites do matter.

Journal: Clinical neuropharmacology20070101

Title: A perspective on adjunctive therapy for Parkinson disease with monoamine oxidase-B inhibition.

Journal: Clinical neuropharmacology20070101

Title: Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers.

Journal: Journal of neural transmission. Supplementum20070101

Title: Pharmacokinetic studies of (-)-deprenyl and some of its metabolites in mouse.

Journal: Journal of neural transmission. Supplementum20070101

Title: Treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials.

Journal: Psychopharmacology bulletin20070101

Title: Commentary on the treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials.

Journal: Psychopharmacology bulletin20070101

Title: Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090.

Journal: HIV clinical trials20070101

Title: Simultaneous determination of selegiline and desmethylselegiline in human body fluids by headspace solid-phase microextraction and gas chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20061205

Title: Double-blind, placebo-controlled trial of selegiline transdermal system (STS) for the treatment of cocaine dependence.

Journal: Drug and alcohol dependence20061201

Title: Selegiline transdermal system in the prevention of relapse of major depressive disorder: a 52-week, double-blind, placebo-substitution, parallel-group clinical trial.

Journal: Journal of clinical psychopharmacology20061201

Title: L-methamphetamine and selective MAO inhibitors decrease morphine-reinforced and non-reinforced behavior in rats; Insights towards selegiline's mechanism of action.

Journal: Pharmacology, biochemistry, and behavior20061201

Title: The path from anti Parkinson drug selegiline and rasagiline to multifunctional neuroprotective anti Alzheimer drugs ladostigil and m30.

Journal: Current Alzheimer research20061201

Title: Monoamine oxidase inhibitory coumarins from the aerial parts of Dictamnus albus.

Journal: Archives of pharmacal research20061201

Title: A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [11C]-GR205171, [11C]-L-deuterium-deprenyl, [11C]-5-Hydroxy-L-Tryptophan, [11C]-L-DOPA and Pittsburgh Compound-B.

Journal: NeuroImage20061101

Title: Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases.

Journal: Current drug targets20061101

Title: Acute effects of moclobemide and deprenyl on 5-HT synthesis rates in the rat brain: An autoradiographic study.

Journal: Brain research bulletin20061016

Title: Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia20061001

Title: A systematic review of research on strategies for the management of antipsychotic-induced sexual dysfunction: high-level evidence is needed.

Journal: The Journal of clinical psychiatry20061001

Title: Hypersexuality and paraphilia induced by selegiline in Parkinson's disease: report of 2 cases.

Journal: Parkinsonism & related disorders20060901

Title: Selegiline transdermal system for the treatment of major depressive disorder: an 8-week, double-blind, placebo-controlled, flexible-dose titration trial.

Journal: The Journal of clinical psychiatry20060901

Title: The combined use of human neural and liver cell lines and mouse hepatocytes improves the predictability of the neurotoxicity of selected drugs.

Journal: Toxicology letters20060820

Title: Cytoprotective effect of two synthetic enhancer substances, (-)-BPAP and (-)-deprenyl, on human brain capillary endothelial cells and rat PC12 cells.

Journal: Life sciences20060808

Title: (-)-Trans-epsilon-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity.

Journal: European journal of pharmacology20060807

Title: Tyramine pressor sensitivity during treatment with the selegiline transdermal system 6 mg/24 h in healthy subjects.

Journal: Journal of clinical pharmacology20060801

Title: Effects of subchronic treatment with selegiline on L-DOPA-induced increase in extracellular dopamine level in rat striatum.

Journal: Journal of pharmacological sciences20060801

Title: Placebo-controlled study examining effects of selegiline in children with attention-deficit/hyperactivity disorder.

Journal: Journal of child and adolescent psychopharmacology20060801

Title: A new way to deliver psychiatric meds.

Journal: Behavioral healthcare20060801

Title: Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.

Journal: The Cochrane database of systematic reviews20060719

Title: [Molecular mechanisms of the neuroprotective effect of (-)-deprenyl].

Journal: Orvosi hetilap20060709

Title: L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats.

Journal: Neurochemistry international20060701

Title: Neuroprotective role of Bacopa monniera extract against aluminium-induced oxidative stress in the hippocampus of rat brain.

Journal: Neurotoxicology20060701

Title: Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.

Journal: Neurobiology of disease20060701

Title: Transdermal selegiline: a novel MAOI formulation for depression.

Journal: Journal of psychosocial nursing and mental health services20060701

Title: Disease progression and pharmacodynamics in Parkinson disease - evidence for functional protection with levodopa and other treatments.

Journal: Journal of pharmacokinetics and pharmacodynamics20060601

Title: High-throughput screening for monoamine oxidase-A and monoamine oxidase-B inhibitors using one-step fluorescence assay.

Journal: Acta pharmacologica Sinica20060601

Title: Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease.

Journal: Neurology20060523

Title: Transdermal selegiline (Emsam).

Journal: The Medical letter on drugs and therapeutics20060522

Title: Initial pharmacotherapy in a population of veterans with Parkinson disease.

Journal: Neurology20060509

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Leading the way: advances in the diagnosis, treatment, and management of neuropsychiatric illnesses.

Journal: CNS spectrums20060501

Title: Transdermal selegiline: the new generation of monoamine oxidase inhibitors.

Journal: CNS spectrums20060501

Title: Why the transdermal delivery of selegiline (6 mg/24 hr) obviates the need for a dietary restriction on tyramine.

Journal: Journal of psychiatric practice20060501

Title: Amphetamine-induced locomotor activity is reduced in mice following MPTP treatment but not following selegiline/MPTP treatment.

Journal: Pharmacology, biochemistry, and behavior20060501

Title: High-performance liquid chromatographic-mass spectrometric determination of methamphetamine and amphetamine enantiomers, desmethylselegiline and selegiline, in hair samples of long-term methamphetamine abusers or selegiline users.

Journal: Journal of analytical toxicology20060501

Title: The necessity of having a proper dose of (-)deprenyl (D) to prolong the life spans of rats explains discrepancies among different studies in the past.

Journal: Annals of the New York Academy of Sciences20060501

Title: Selegiline slows the progression of the symptoms of Parkinson disease.

Journal: Neurology20060425

Title: Patient page. Slowing down a 'slow' movement disorder: selegiline's benefit in treating Parkinson disease.

Journal: Neurology20060425

Title: Metabolic transformation plays a primary role in the psychostimulant-like discriminative-stimulus effects of selegiline [(R)-(-)-deprenyl].

Journal: The Journal of pharmacology and experimental therapeutics20060401

Title: Novel transdermal delivery formulation of the monoamine oxidase inhibitor selegiline nearing release for treatment of depression.

Journal: The Journal of clinical psychiatry20060401

Title: Effects of co-administration of a selective serotonin reuptake inhibitor and monoamine oxidase inhibitors on 5-HT-related behavior in rats.

Journal: European journal of pharmacology20060227

Title: The use of LC/MS, GC/MS, and LC/NMR hyphenated techniques to identify a drug degradation product in pharmaceutical development.

Journal: Journal of pharmaceutical and biomedical analysis20060224

Title: Effects of selegiline on antioxidant systems in the nigrostriatum in rat.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20060201

Title: Modulation of brain mitochondrial function by deprenyl.

Journal: Neurochemistry international20060201

Title: Clomipramine and selegiline: do they influence impulse control?

Journal: Journal of veterinary pharmacology and therapeutics20060201

Title: H MRS identifies lactate rise in the striatum of MPTP-treated C57BL/6 mice.

Journal: The European journal of neuroscience20060201

Title: Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins.

Journal: Biochemical and biophysical research communications20060120

Title: Acute and delayed effect of (-) deprenyl and (-) 1-phenyl-2-propylaminopentane (PPAP) on the serotonin content of peritoneal cells (white blood cells and mast cells).

Journal: Cell biochemistry and function20060101

Title: Deprenyl and the relationship between its effects on spatial memory, oxidant stress and hippocampal neurons in aged male rats.

Journal: Physiological research20060101

Title: Chronic exposure of rats to cognition enhancing drugs produces a neuroplastic response identical to that obtained by complex environment rearing.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20060101

Title: Major depression and the synthetic enhancer substances, (-)-deprenyl and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20060101

Title: A comparison of drug-seeking behavior maintained by D-amphetamine, L-deprenyl (selegiline), and D-deprenyl under a second-order schedule in squirrel monkeys.

Journal: Psychopharmacology20060101

Title: Efficacy and safety of high-dose cabergoline in Parkinson's disease.

Journal: Acta neurologica Scandinavica20060101

Title: Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness.

Journal: British journal of pharmacology20060101

Title: Effect of nerodilol, carvone and anethole on the in vitro transdermal delivery of selegiline hydrochloride.

Journal: Die Pharmazie20060101

Title: Treatment of primary progressive freezing of gait with high doses of selegiline.

Journal: Clinical neuropharmacology20060101

Title: Persistent sexual side effects after SSRI discontinuation.

Journal: Psychotherapy and psychosomatics20060101

Title: Quality of life in Parkinson's disease--Indian scenario.

Journal: The Journal of the Association of Physicians of India20060101

Title: Contemporary issues in the treatment of Alzheimer's disease: tangible benefits of current therapies.

Journal: The Journal of clinical psychiatry20060101

Title: Variation in neurophysiological function and evidence of quantitative electroencephalogram discordance: predicting cocaine-dependent treatment attrition.

Journal: The Journal of neuropsychiatry and clinical neurosciences20060101

Title: First depression patch approved.

Journal: FDA consumer20060101

Title: [Interaction of pyruvate kinase with isatin and deprenyl].

Journal: Biomeditsinskaia khimiia20060101

Title: Therapeutic options for cognitive decline in senior pets.

Journal: Journal of the American Animal Hospital Association20060101

Title: Selegiline induces neuronal phenotype and neurotrophins expression in embryonic stem cells.

Journal: Rejuvenation research20060101

Title: Isatin interaction with glyceraldehyde-3-phosphate dehydrogenase, a putative target of neuroprotective drugs: partial agonism with deprenyl.

Journal: Journal of neural transmission. Supplementum20060101

Title: Deprenyl: from chemical synthesis to neuroprotection.

Journal: Journal of neural transmission. Supplementum20060101

Title: Low dose (-)deprenyl is cytoprotective: it maintains mitochondrial membrane potential and eliminates oxygen radicals.

Journal: Life sciences20051205

Title: A comprehensive assessment of the safety of intravenous methamphetamine administration during treatment with selegiline.

Journal: Pharmacology, biochemistry, and behavior20051201

Title: Dementia.

Journal: Clinical evidence20051201

Title: Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.

Journal: Brain research. Molecular brain research20051130

Title: Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.

Journal: Brain research. Molecular brain research20051118

Title: Increased cell-cell adhesion, a novel effect of R-(-)-deprenyl.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20051101

Title: Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl.

Journal: Molecular pharmacology20051101

Title: Selegiline protects against recognition memory impairment induced by neonatal iron treatment.

Journal: Experimental neurology20051101

Title: Harmane inhibits serotonergic dorsal raphe neurons in the rat.

Journal: Psychopharmacology20051101

Title: Parkinson's disease and sleep.

Journal: Neurologic clinics20051101

Title: Selegiline orally disintegrating tablets for the treatment of Parkinson's disease.

Journal: Expert review of neurotherapeutics20051101

Title: Recent advances in Parkinson's disease therapy: use of monoamine oxidase inhibitors.

Journal: Expert review of neurotherapeutics20051101

Title: Would caregivers of Alzheimer disease patients involve their relative in a decision to use an AD-slowing medication?

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry20051101

Title: 2-Phenylethylamine in combination with l-deprenyl lowers the striatal level of dopamine and prolongs the duration of the stereotypy in mice.

Journal: Pharmacology, biochemistry, and behavior20051101

Title: Effects of monoamine oxidase inhibitors on methamphetamine-induced stereotypy in mice and rats.

Journal: Neurochemical research20051101

Title: Discriminative stimulus and reinforcing effects of p-fluoro-L-deprenyl in monkeys.

Journal: Psychopharmacology20051001

Title: Antidepressant-like effects of selegiline in the forced swim test.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20051001

Title: In vivo measurement of brain monoamine oxidase B occupancy by rasagiline, using (11)C-l-deprenyl and PET.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20051001

Title: Protein aggregation in retinal cells and approaches to cell protection.

Journal: Cellular and molecular neurobiology20050901

Title: Effects of selegiline alone or with donepezil on memory impairment in rats.

Journal: European journal of pharmacology20050822

Title: LED fluorescence spectroscopy for direct determination of monoamine oxidase B inactivation.

Journal: Analytical biochemistry20050815

Title: Clinical pharmacology of rasagiline: a novel, second-generation propargylamine for the treatment of Parkinson disease.

Journal: Journal of clinical pharmacology20050801

Title: Reexamination of the TEMPO Study.

Journal: Archives of neurology20050801

Title: Rasagiline.

Journal: Nature reviews. Drug discovery20050801

Title: Monoamine oxidase B inhibitors for early Parkinson's disease.

Journal: The Cochrane database of systematic reviews20050720

Title: Evidence for reduced arterial plasma input, prolonged lung retention and reduced lung monoamine oxidase in smokers.

Journal: Nuclear medicine and biology20050701

Title: Detection of N-monomethyl-lysine generated by metabolic transmethylation.

Journal: Analytical and bioanalytical chemistry20050601

Title: Contribution of L-3,4-dihydroxyphenylalanine metabolism to the inhibition of gluconeogenesis in rabbit kidney-cortex tubules.

Journal: The international journal of biochemistry & cell biology20050601

Title: Administration of selegiline is not associated with visual hallucinations in advanced Parkinson's disease patients.

Journal: Parkinsonism & related disorders20050601

Title: Reversal of age-related deficits in object recognition memory in rats with l-deprenyl.

Journal: Experimental gerontology20050601

Title: Parkinson's disease.

Journal: Clinical evidence20050601

Title: Parkinson's disease. Diagnosis and the initiation of therapy.

Journal: Minerva medica20050601

Title: Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.

Journal: Movement disorders : official journal of the Movement Disorder Society20050501

Title: [A case of interval form of carbon monoxide poisoning with a remarkable recovery].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics20050501

Title: Mechanism of 1-methyl-4-phenylpyridinium-induced dopamine release from PC12 cells.

Journal: Neurochemical research20050501

Title: HPLC and HPLC-MS analysis of urinary N(epsilon)-monomethyl-lysine.

Journal: Journal of chromatographic science20050401

Title: [Role of R-(-)-deprenyl in adhesion of neuronal and non-neuronal cells].

Journal: Orvosi hetilap20050327

Title: 'Levodopa phobia': a new iatrogenic cause of disability in Parkinson disease.

Journal: Neurology20050308

Title: Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice.

Journal: Neuroscience research20050301

Title: Therapeutic agents for the treatment of cognitive dysfunction syndrome in senior dogs.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20050301

Title: Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002.

Journal: Synapse (New York, N.Y.)20050201

Title: The effects of acute loading with levodopa and levodopa with selegiline on blood pressure and plasma norepinephrine levels in chronic Parkinson's disease patients.

Journal: Acta neurologica Scandinavica20050201

Title: Double-blind, placebo-controlled, multicenter trial of selegiline augmentation of antipsychotic medication to treat negative symptoms in outpatients with schizophrenia.

Journal: The American journal of psychiatry20050201

Title: Effects of high-dose selegiline on morphine reinforcement and precipitated withdrawal in dependent rats.

Journal: Behavioural pharmacology20050201

Title: Selegiline in the management of apathy following traumatic brain injury.

Journal: Brain injury20050201

Title: Survival in Parkinson disease: thirteen-year follow-up of the DATATOP cohort.

Journal: Neurology20050111

Title: Selegiline modifies the extinction of responding following morphine self-administration, but does not alter cue-induced reinstatement, reacquisition of morphine reinforcement, or precipitated withdrawal.

Journal: Pharmacological research20050101

Title: Molecular characterization of monoamine oxidase in zebrafish (Danio rerio).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology20050101

Title: Marked effect of liver and kidney function on the pharmacokinetics of selegiline.

Journal: Clinical pharmacology and therapeutics20050101

Title: Intracellular dopamine oxidation mediates rotenone-induced apoptosis in PC12 cells.

Journal: Acta pharmacologica Sinica20050101

Title: Inhibition of methamphetamine-induced hyperlocomotion in mice by clorgyline, a monoamine oxidase-a inhibitor, through alteration of the 5-hydroxytriptamine turnover in the striatum.

Journal: Neuroscience20050101

Title: sgk1, a member of an RNA cluster associated with cell death in a model of Parkinson's disease.

Journal: The European journal of neuroscience20050101

Title: Other pharmacological treatments for motor complications and dyskinesias.

Journal: Movement disorders : official journal of the Movement Disorder Society20050101

Title: Dislocation of the glenoid fossa.

Journal: Journal of shoulder and elbow surgery20050101

Title: 'My involvement in aging research was just a series of coincidences' An interview with Kenichi Kitani. Interview by Sataro Goto.

Journal: Biogerontology20050101

Title: Remarkable effect of selegiline (L-deprenyl), a selective monoamine oxidase type-B inhibitor, in a patient with severe refractory depression: a case report.

Journal: Clinical neuropharmacology20050101

Title: A rapid, sensitive electron-capture gas chromatographic procedure for analysis of metabolites of N-methyl,N-propargylphenylethylamine, a potential neuroprotective agent.

Journal: Journal of pharmacological and toxicological methods20050101

Title: Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model.

Journal: Endocrine research20050101

Title: Dose-dependency of life span prolongation of F344/DuCrj rats injected with (-)deprenyl.

Journal: Biogerontology20050101

Title: [Alzheimer's disease therapy--theory and practice].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960)20050101

Title: Deprenyl, a therapeutic agent for Parkinson's disease, inhibits arsenic toxicity potentiated by GSH depletion via inhibition of JNK activation.

Journal: Journal of toxicology and environmental health. Part A20041201

Title: Indolalkylamines derivatives as antioxidant and neuroprotective agents in an experimental model of Parkinson's disease.

Journal: Medical science monitor : international medical journal of experimental and clinical research20041201

Title: Treatment possibilities of Alzheimer's disease.

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology20041201

Title: The use of the synthetic enhancer substances (-)-deprenyl and (-)-BPAP in major depression.

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology20041201

Title: Preclinical evidence for neuroprotection with monoamine oxidase-B inhibitors in Parkinson's disease.

Journal: Neurology20041012

Title: A novel formulation of selegiline for the treatment of Parkinson's disease.

Journal: Neurology20041012

Title: Clinical trials of neuroprotection for Parkinson's disease.

Journal: Neurology20041012

Title: A review of the mechanisms and role of monoamine oxidase inhibitors in Parkinson's disease.

Journal: Neurology20041012

Title: Cardiovascular activity of rasagiline, a selective and potent inhibitor of mitochondrial monoamine oxidase B: comparison with selegiline.

Journal: British journal of pharmacology20041001

Title: Levodopa-responsive parkinsonism in hereditary spastic paraplegia with thin corpus callosum.

Journal: Parkinsonism & related disorders20041001

Title: In vitro confirmation of selegiline N-oxidation by flavin-containing monooxygenase in rat microsome using LC-ESI MS.

Journal: Biological & pharmaceutical bulletin20041001

Title: Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice.

Journal: European journal of pharmacology20040919

Title: Pitfalls of animal model systems in ageing research.

Journal: Best practice & research. Clinical endocrinology & metabolism20040901

Title: Effects of repeated administration of Uncaria hooks on the acquisition and central neuronal activities in ethanol-treated mice.

Journal: Journal of ethnopharmacology20040901

Title: (-)-Deprenyl alleviates the degenerative changes induced in the neonatal rat spinal cord by CSF from amyotrophic lateral sclerosis patients.

Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases20040901

Title: High-performance liquid chromatography/tandem mass spectrometry assay for the determination of 1-methyl-4-phenyl pyridinium (MPP+) in brain tissue homogenates.

Journal: Journal of neuroscience methods20040830

Title: 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake transporter, and monoamine oxidase-B.

Journal: Neuroscience letters20040826

Title: Subthalamic deep brain stimulation masking possible malignant syndrome in Parkinson disease.

Journal: Neurology20040810

Title: Pharmacological aspects of (-)-deprenyl.

Journal: Current medicinal chemistry20040801

Title: Assessment of the N-oxidation of deprenyl, methamphetamine, and amphetamine enantiomers by chiral capillary electrophoresis: an in vitro metabolism study.

Journal: Electrophoresis20040801

Title: Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20040801

Title: Selegiline potentiates the effects of EGb 761 in response to ischemic brain injury.

Journal: Neurochemistry international20040701

Title: Selegiline, an MAO-B inhibitor, attenuates airway smooth muscle contraction in the rat trachea.

Journal: The Journal of pharmacy and pharmacology20040701

Title: Selegiline increases heme oxygenase-1 expression and the cytotoxicity produced by dopamine treatment of neuroblastoma SK-N-SH cells.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas20040701

Title: Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs.

Journal: Toxicology letters20040615

Title: Therapeutic factors causing hallucination in Parkinson's disease patients, especially those given selegiline.

Journal: Parkinsonism & related disorders20040601

Title: Dementia.

Journal: Clinical evidence20040601

Title: Parkinson's disease.

Journal: Clinical evidence20040601

Title: 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells.

Journal: Journal of neuroscience research20040515

Title: Pharmacological studies with endogenous enhancer substances: beta-phenylethylamine, tryptamine, and their synthetic derivatives.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20040501

Title: Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells.

Journal: Investigative ophthalmology & visual science20040501

Title: A 'cure' for Parkinson's disease: can neuroprotection be proven with current trial designs?

Journal: Movement disorders : official journal of the Movement Disorder Society20040501

Title: Inefficacy of selegiline in treatment of canine pituitary-dependent hyperadrenocorticism.

Journal: Australian veterinary journal20040501

Title: Comparison of the binding of the irreversible monoamine oxidase tracers, [(11)C]clorgyline and [(11)C]l-deprenyl in brain and peripheral organs in humans.

Journal: Nuclear medicine and biology20040401

Title: Cardiopulmonary effects of medetomidine, oxymorphone, or butorphanol in selegiline-treated dogs.

Journal: Veterinary anaesthesia and analgesia20040401

Title: Zydis selegiline reduces off time in Parkinson's disease patients with motor fluctuations: a 3-month, randomized, placebo-controlled study.

Journal: Movement disorders : official journal of the Movement Disorder Society20040401

Title: Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs.

Journal: Acta neuropathologica20040301

Title: (-)-Deprenyl inhibits tyramine-induced noradrenaline release, but not tyramine-induced dopamine release or potassium-induced noradrenaline release, from rat brain synaptosomes.

Journal: Pharmacological research20040301

Title: Transdermal selegiline and intravenous cocaine: safety and interactions.

Journal: Psychopharmacology20040201

Title: l-Deprenyl prevents lipid peroxidation and memory deficits produced by cerebral ischemia in rats.

Journal: Cellular and molecular neurobiology20040201

Title: Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline.

Journal: Neuroscience letters20040130

Title: Positive effects of deprenyl and estradiol on spatial memory and oxidant stress in aged female rat brains.

Journal: Neuroscience letters20040116

Title: Comparative study of the effects of isatin, an endogenous MAO-inhibitor, and selegiline on bradykinesia and dopamine levels in a rat model of Parkinson's disease induced by the Japanese encephalitis virus.

Journal: Neurotoxicology20040101

Title: (-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.

Journal: Neurotoxicology20040101

Title: Adverse effects of dopamine potentiation by long-term treatment with selegiline.

Journal: Movement disorders : official journal of the Movement Disorder Society20040101

Title: Chiral separation of deprenyl-N-oxide isomers by capillary electrophoresis using various cyclodextrin derivatives.

Journal: Journal of chromatographic science20040101

Title: [Prognosis in Alzheimer's disease].

Journal: Nihon rinsho. Japanese journal of clinical medicine20040101

Title: Effects of the DT-diaphorase inhibitor dicumarol on striatal monoamine levels in L-DOPA and L-deprenyl pre-treated rats.

Journal: Neurotoxicity research20040101

Title: Brain cholinesterases: III. Future perspectives of AD research and clinical practice.

Journal: Medical hypotheses20040101

Title: Effects of dopaminergic treatment on bladder function in Parkinson's disease.

Journal: Neurourology and urodynamics20040101

Title: In vitro formation of selegiline-N-oxide as a metabolite of selegiline in human, hamster, mouse, rat, guinea-pig, rabbit and dog.

Journal: European journal of drug metabolism and pharmacokinetics20040101

Title: [The effect of long-term administration of isatin and himantan to mice on sensitivity of brain monoamine oxidase B to inhibition by deprenyl in vivo and in vitro].

Journal: Biomeditsinskaia khimiia20040101

Title: Selegiline in comparison with methylphenidate in attention deficit hyperactivity disorder children and adolescents in a double-blind, randomized clinical trial.

Journal: Journal of child and adolescent psychopharmacology20040101

Title: Increased striatal neuropeptide Y immunoreactivity and its modulation by deprenyl, clonidine and L-dopa in MPTP-treated mice.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20031201

Title: Analysis of benzene ethylamine derivatives in urine using the programmable dynamic liquid-phase microextraction (LPME) device.

Journal: The Analyst20031201

Title: The effects of chronic administration of inhibitors of flavin and quinone amine oxidases on imidazoline I(1) receptor density in rat whole brain.

Journal: Annals of the New York Academy of Sciences20031201

Title: Relationship between imidazoline(2) sites and monoamine oxidase.

Journal: Annals of the New York Academy of Sciences20031201

Title: Pro-apoptotic and anti-apoptotic molecules affecting pathways of signal transduction.

Journal: Annals of the New York Academy of Sciences20031201

Title: Parkinson's disease.

Journal: Clinical evidence20031201

Title: Reduced cardiovascular effects of methamphetamine following treatment with selegiline.

Journal: Drug and alcohol dependence20031124

Title: Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity.

Journal: British journal of cancer20031117

Title: Transdermal selegiline: targeted effects on monoamine oxidases in the brain.

Journal: Biological psychiatry20031115

Title: L-Deprenyl as an inhibitor of menadione-induced permeability transition in liver mitochondria.

Journal: Biochemical pharmacology20031101

Title: Clinical inquiries. What is the best initial treatment of Parkinson's disease?

Journal: The Journal of family practice20031101

Title: Selegiline reduces N-methyl-D-aspartic acid induced perturbation of neurotransmission but it leaves NMDA receptor dependent long-term potentiation intact in the hippocampus.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20031101

Title: A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20031101

Title: A new low-dose formulation of selegiline: clinical efficacy, patient preference and selectivity for MAO-B inhibition.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20031101

Title: Selegiline's neuroprotective capacity revisited.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20031101

Title: L-DOPA-induced excessive daytime sleepiness in PD: a placebo-controlled case with MSLT assessment.

Journal: Neurology20031014

Title: D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity.

Journal: Synapse (New York, N.Y.)20031001

Title: A randomized controlled trial of oral selegiline plus nicotine skin patch compared with placebo plus nicotine skin patch for smoking cessation.

Journal: Addiction (Abingdon, England)20031001

Title: Pharmacologic treatment of Alzheimer's disease: an update.

Journal: American family physician20031001

Title: Sublingual selegiline: new formulation. New formulation: new risk of oral adverse effects.

Journal: Prescrire international20031001

Title: L-selegiline potentiates the cellular poly(ADP-ribosyl)ation response to ionizing radiation.

Journal: The Journal of pharmacology and experimental therapeutics20030901

Title: Selegiline long-term effects on brain acetylcholinesterase, (Na+,K+)-ATPase activities, antioxidant status and learning performance of aged rats.

Journal: Pharmacological research20030901

Title: Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations.

Journal: Journal of neurochemistry20030901

Title: Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.

Journal: Drug metabolism and disposition: the biological fate of chemicals20030901

Title: Deprenyl blocks the aglycemia-induced depression of the synaptic transmission but not the ischemia-induced depression in neonatal rat spinal cord in vitro.

Journal: Neuroscience research20030901

Title: Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD.

Journal: Neurology20030812

Title: [Therapy for patients with early-stage Parkinson's disease].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine20030810

Title: Enhancer regulation/endogenous and synthetic enhancer compounds: a neurochemical concept of the innate and acquired drives.

Journal: Neurochemical research20030801

Title: Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture.

Journal: Neuroscience research20030801

Title: Effects of monoamine oxidase inhibitors on the diethyldithiocarbamate-induced enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in C57BL/6 mice.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20030801

Title: Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20030801

Title: Chiral characterization of deprenyl-N-oxide and other deprenyl metabolites by capillary electrophoresis using a dual cyclodextrin system in rat urine.

Journal: Electrophoresis20030801

Title: Selegiline in the treatment of attention deficit hyperactivity disorder in children: a double blind and randomized trial.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20030801

Title: Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats.

Journal: Brain research20030627

Title: Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons.

Journal: Antioxidants & redox signaling20030601

Title: An HPLC tracing of the enhancer regulation in selected discrete brain areas of food-deprived rats.

Journal: Life sciences20030509

Title: Enhancer substances: selegiline and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes.

Journal: Life sciences20030502

Title: Neuroprotection by deprenyl and other propargylamines: glyceraldehyde-3-phosphate dehydrogenase rather than monoamine oxidase B.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20030501

Title: Environmental influence on recovery after brain lesions--experimental and clinical data.

Journal: Journal of rehabilitation medicine20030501

Title: Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons.

Journal: Journal of neurocytology20030501

Title: A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (selegiline), alpha-tocopherol was ineffective in the DATATOP study.

Journal: Life sciences20030425

Title: Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine.

Journal: Synapse (New York, N.Y.)20030401

Title: Quantitative analysis of desmethylselegiline, methamphetamine, and amphetamine in hair and plasma from Parkinson patients on long-term selegiline medication.

Journal: Journal of analytical toxicology20030401

Title: Selegiline in the treatment of Parkinson's disease: its impact on orthostatic hypotension.

Journal: Parkinsonism & related disorders20030301

Title: Safety of selegiline with cold medications.

Journal: The Annals of pharmacotherapy20030301

Title: [Biomedical imaging in pharmacology with nuclear medical imaging methodologies: positron emission tomography (PET) and single photon emission computed tomography (SPECT)].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica20030301

Title: Monoamine oxidase inhibitors--is it time to up the TEMPO?

Journal: The Lancet. Neurology20030301

Title: Selegiline attenuates cardiac oxidative stress and apoptosis in heart failure: association with improvement of cardiac function.

Journal: European journal of pharmacology20030214

Title: l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20030201

Title: A double-blind, placebo-controlled trial of the safety and efficacy of selegiline transdermal system without dietary restrictions in patients with major depressive disorder.

Journal: The Journal of clinical psychiatry20030201

Title: The relevance of preclinical studies for the treatment of Parkinson's disease.

Journal: Journal of neurology20030201

Title: A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation.

Journal: Biological psychiatry20030115

Title: Protective effects of selegiline and desmethylselegiline against N-methyl-D-aspartate-induced rat retinal damage.

Journal: European journal of pharmacology20030101

Title: Evidence for dopamine-derived hydroxyl radical formation in the nigrostriatal system in response to axotomy.

Journal: Free radical biology & medicine20030101

Title: Selegiline for Alzheimer's disease.

Journal: The Cochrane database of systematic reviews20030101

Title: In vivo imaging of brain dopaminergic neurotransmission system in small animals with high-resolution single photon emission computed tomography.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20030101

Title: Selegiline-transdermal--Somerset: Emsam.

Journal: Drugs in R&D20030101

Title: Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion.

Journal: Neurobiology of aging20030101

Title: Daily transdermal administration of selegiline to guinea-pigs preferentially inhibits monoamine oxidase activity in brain when compared with intestinal and hepatic tissues.

Journal: The Journal of pharmacy and pharmacology20030101

Title: Neuroprotection for Parkinson's disease: prospects and promises.

Journal: Annals of neurology20030101

Title: Lack of influence of the apolipoprotein E genotype on the outcome of selegiline treatment in Alzheimer's disease.

Journal: Dementia and geriatric cognitive disorders20030101

Title: Neurostimulatory and antioxidative effects of L-deprenyl in aged rat brain regions.

Journal: Biogerontology20030101

Title: Clinical pharmacokinetics of cabergoline.

Journal: Clinical pharmacokinetics20030101

Title: Selegiline in the treatment of sexual dysfunction in schizophrenic patients maintained on neuroleptics: a pilot study.

Journal: Clinical neuropharmacology20030101

Title: Noncholinergic treatment options for Alzheimer's disease.

Journal: The Journal of clinical psychiatry20030101

Title: Arguments for the use of dopamine receptor agonists in clinical and preclinical Parkinson's disease.

Journal: Journal of neural transmission. Supplementum20030101

Title: Antioxidant properties of newly synthesized N-propargylamine derivatives of nitroxyl: a comparison with deprenyl.

Journal: Polish journal of pharmacology20030101

Title: Neuroprotective effect of deprenyl in sensory neurons of axotomized dorsal root ganglion.

Journal: Clinical neuropharmacology20030101

Title: [Mild cognitive impairment].

Journal: Ryoikibetsu shokogun shirizu20030101

Title: [Effect of a new antiparkinsonian drug himantane on monoamine oxidase activity].

Journal: Eksperimental'naia i klinicheskaia farmakologiia20030101

Title: Medical treatment of hyperadrenocorticism in the dog.

Journal: Australian veterinary journal20030101

Title: Detection, quantification, metabolism, and behavioral effects of selegiline in horses.

Journal: Veterinary therapeutics : research in applied veterinary medicine20030101

Title: Selegiline enhances erectile activity induced by dopamine injection in the paraventricular nucleus of the hypothalamus in anesthetized rats.

Journal: International journal of impotence research20021201

Title: [Long-term treatment of Parkinson's disease patients with selegiline hydrochloride (FPF 1100): outcome of 5-year treatment].

Journal: No to shinkei = Brain and nerve20021201

Title: Recent advances in Parkinson's disease.

Journal: Ideggyogyaszati szemle20021120

Title: Transdermal selegiline in major depression: a double-blind, placebo-controlled, parallel-group study in outpatients.

Journal: The American journal of psychiatry20021101

Title: Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits.

Journal: Neuropharmacology20021101

Title: Effects of short- and long-term (--)-deprenyl administration on mRNA for copper, zinc- and manganese-superoxide dismutase and glutathione peroxidase in rat brain.

Journal: Brain research20021025

Title: PET imaging of monoamine oxidase B in peripheral organs in humans.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20021001

Title: Quantitative analysis of selegiline and three metabolites (N-desmethylselegiline, methamphetamine, and amphetamine) in human plasma by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.

Journal: Journal of analytical toxicology20021001

Title: Practical importance of neuroprotection in Parkinson's disease.

Journal: Journal of neurology20021001

Title: 1-(Benzofuran-2-yl)-2-(3,3,3-trifluoropropyl)aminopentane HCl, 3-F-BPAP, antagonizes the enhancer effect of (-)-BPAP in the shuttle box and leaves the effect of (-)-deprenyl unchanged.

Journal: Life sciences20020913

Title: Effects of selegiline (L-deprenyl) during smoking and short-term abstinence.

Journal: Psychopharmacology20020901

Title: Urinary excretion of selegiline N-oxide, a new indicator for selegiline administration in man.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20020901

Title: Selegiline: a second look. Six years later: too risky in Parkinson's disease.

Journal: Prescrire international20020801

Title: Selegiline transdermal system Somerset.

Journal: Current opinion in investigational drugs (London, England : 2000)20020801

Title: Effects of (-)deprenyl (selegiline) on acetylcholinesterase and Na(+),K(+)-ATPase activities in adult rat whole brain.

Journal: Pharmacological research20020801

Title: Treatment of an acromegalic cat with the dopamine agonist L-deprenyl.

Journal: Australian veterinary journal20020801

Title: [The usefulness of dopaminergic drugs in traumatic brain injury].

Journal: Revista de neurologia20020801

Title: Neurological effects of psychopharmacological agents.

Journal: Seminars in clinical neuropsychiatry20020701

Title: Effect of concomitant hormone replacement therapy containing estradiol and levonorgestrel on the pharmacokinetics of selegiline.

Journal: European journal of clinical pharmacology20020701

Title: Smoking cessation and panic attacks: a report of 2 cases.

Journal: The Journal of clinical psychiatry20020701

Title: Electroencephalographic activation by tacrine, deprenyl, and quipazine: cholinergic vs. non-cholinergic contributions.

Journal: European journal of pharmacology20020628

Title: Effects of selegiline, phenylpropanolamine, or a combination of both on physiologic and behavioral variables in healthy dogs.

Journal: American journal of veterinary research20020601

Title: Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results.

Journal: Journal of occupational and environmental medicine20020501

Title: (-)-Deprenyl fails to promote axonal regeneration of retinal ganglion cells in vitro and in vivo.

Journal: Cell and tissue research20020501

Title: The effect of deprenyl washout in patients with long-standing Parkinson's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20020501

Title: Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial.

Journal: Annals of neurology20020501

Title: Modulation of neuroendocrine--immune signaling by L-deprenyl and L-desmethyldeprenyl in aging and mammary cancer.

Journal: Mechanisms of ageing and development20020430

Title: Why (--)deprenyl prolongs survivals of experimental animals: increase of anti-oxidant enzymes in brain and other body tissues as well as mobilization of various humoral factors may lead to systemic anti-aging effects.

Journal: Mechanisms of ageing and development20020430

Title: Pharmacological interventions in aging and age-associated disorders: potentials of propargylamines for human use.

Journal: Annals of the New York Academy of Sciences20020401

Title: Effects of selegiline on fronto-temporal dementia: a neuropsychological evaluation.

Journal: International journal of geriatric psychiatry20020401

Title: [Serotonin syndrome: report of a fatal case and review of the literature].

Journal: Revista clinica espanola20020401

Title: [The evolution of use of anti-Parkinson drugs in Spain].

Journal: Revista de neurologia20020401

Title: Inhibition of human LDL oxidation by the neuroprotective drug l-deprenyl.

Journal: Neurological research20020301

Title: Placebo-associated improvements in motor function: comparison of subjective and objective sections of the UPDRS in early Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society20020301

Title: Treatment of periodic limb movements in sleep with selegiline HCl.

Journal: Movement disorders : official journal of the Movement Disorder Society20020301

Title: Effect of R-(-)-deprenyl and harmaline on dopamine- and peroxynitrite-induced membrane permeability transition in brain mitochondria.

Journal: Neurochemical research20020301

Title: Rat striatal monoamine oxidase-B inhibition by l-deprenyl and rasagiline: its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease.

Journal: Parkinsonism & related disorders20020301

Title: Neuroprotective actions of selegiline.

Journal: Journal of neuroscience research20020201

Title: The effect of selegiline in the treatment of people with Alzheimer's disease: a meta-analysis of published trials.

Journal: International journal of geriatric psychiatry20020201

Title: Antiapoptotic effect of (-)-deprenyl in rat kidney after ischemia-reperfusion.

Journal: Medical science monitor : international medical journal of experimental and clinical research20020201

Title: Deprenyl protects from MPTP-induced Parkinson-like syndrome and glutathione oxidation in rat striatum.

Journal: Toxicology20020125

Title: The influence of metabolism on the MAO-B inhibitory potency of selegiline.

Journal: Current medicinal chemistry20020101

Title: Effect of repeated treatment with high doses of selegiline on behaviour, striatal dopaminergic transmission and tyrosine hydroxylase mRNA levels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20020101

Title: Nitecapone and selegiline as effective adjuncts to L-DOPA in reserpine-induced catatonia in mice.

Journal: Methods and findings in experimental and clinical pharmacology20020101

Title: Morphometric evaluation of the neuroprotective effect of deprenyl on postaxotomic motor neuron losses.

Journal: Clinical neuropharmacology20020101

Title: [Study of the tissue and subcellular distribution of isatin-binding proteins with optical biosensor].

Journal: Voprosy meditsinskoi khimii20020101

Title: Reversible transvestic fetishism in a man with Parkinson's disease treated with selegiline.

Journal: Clinical neuropharmacology20020101

Title: MAO-B inhibitors for the treatment of Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society20020101

Title: [Monoamine oxidase inhibitors: prospects for the use in clinical practice].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova20020101

Title: The multiple actions of selegiline.

Journal: Proceedings of the Western Pharmacology Society20020101

Title: Monoamine oxidase inhibitors: a new generation.

Journal: Psychopharmacology bulletin20020101

Title: Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.

Journal: The Cochrane database of systematic reviews20020101

Title: [Effectiveness and tolerability of selegiline in the treatment of pathological cerebral involutions].

Journal: La Clinica terapeutica20020101

Title: Zonisamide has beneficial effects on Parkinson's disease patients.

Journal: Neuroscience research20011201

Title: Investigating potential anxiolytic, antidepressant and memory enhancing activity of deprenyl.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20011201

Title: Ten-year follow-up of three different initial treatments in de-novo PD: a randomized trial.

Journal: Neurology20011113

Title: Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice.

Journal: Brain research20011102

Title: (-)-D-Deprenyl attenuates apoptosis in experimental brain ischaemia.

Journal: European journal of pharmacology20011102

Title: CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals20011101

Title: The effects of oral selegiline hydrochloride on learning and training in the dog: a psychobiological interpretation.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20011101

Title: Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.

Journal: Pharmacology & toxicology20011101

Title: Future of neuroprotection in Parkinson's disease.

Journal: Parkinsonism & related disorders20011001

Title: Incorporation of selegiline metabolites into hair after oral selegiline intake.

Journal: Journal of analytical toxicology20011001

Title: Medical treatment of canine pituitary-dependent hyperadrenocorticism (Cushing's disease).

Journal: The Veterinary clinics of North America. Small animal practice20010901

Title: Simultaneous determination of selegiline-N-oxide, a new indicator for selegiline administration, and other metabolites in urine by high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal: Journal of chromatography. B, Biomedical sciences and applications20010805

Title: Inhibition of rat liver microsomal CYP1A2 and CYP2B1 activity by N-(2-heptyl)-N-methyl-propargylamine and by N-(2-heptyl)-propargylamine.

Journal: Drug metabolism and disposition: the biological fate of chemicals20010801

Title: [Parkinson's disease].

Journal: Nihon rinsho. Japanese journal of clinical medicine20010801

Title: Changes in vascular alpha 1- and alpha 2-adrenoceptor responsiveness by selegiline treatment.

Journal: Fundamental & clinical pharmacology20010801

Title: Selegiline and mortality in subjects with Parkinson's disease: a longitudinal community study.

Journal: Neurology20010724

Title: Selegiline and mortality in subjects with Parkinson's disease: a longitudinal community study.

Journal: Neurology20010724

Title: Current advances in Parkinson's disease.

Journal: Trends in neurosciences20010701

Title: Freezing of gait in PD: prospective assessment in the DATATOP cohort.

Journal: Neurology20010626

Title: Oxygen inhalation enhances striatal dopamine metabolism and monoamineoxidase enzyme inhibition prevents it: a microdialysis study.

Journal: European journal of pharmacology20010622

Title: Advances in managing Parkinson's disease.

Journal: Hospital practice (1995)20010615

Title: PET with 11C-deuterium-deprenyl and 18F-FDG in focal epilepsy.

Journal: Acta neurologica Scandinavica20010601

Title: The frissonnant mutant mouse, a model of dopamino-sensitive, inherited motor syndrome.

Journal: Neurobiology of disease20010601

Title: Inhibition of MAO-A activity enhances behavioural activity of rats assessed using water maze and open arena tasks.

Journal: Pharmacology & toxicology20010601

Title: Rescue of dying neurons by (R)-deprenyl in the MPTP-mouse model of Parkinson's disease does not include restoration of neostriatal dopamine.

Journal: Annals of the New York Academy of Sciences20010601

Title: Paroxysmal hypertensive crises induced by selegiline in a patient with Parkinson's disease.

Journal: Journal of neurology20010601

Title: [Parkinson patients. Normal life expectancy with selegiline?].

Journal: MMW Fortschritte der Medizin20010528

Title: Evidence that L-deprenyl treatment for one week does not inhibit MAO A or the dopamine transporter in the human brain.

Journal: Life sciences20010504

Title: Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2-propylaminopentane, ((-)BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain.

Journal: Bioorganic & medicinal chemistry20010501

Title: CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline.

Journal: European journal of clinical pharmacology20010501

Title: Monoamine oxidase assays.

Journal: Current protocols in pharmacology20010501

Title: L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: a microdialysis study in rats.

Journal: Neuroscience letters20010420

Title: Selective inhibition of MAO-B through chronic low-dose (R)-deprenyl treatment in C57BL/6 mice has no effect on basal neostriatal dopamine levels.

Journal: Experimental neurology20010401

Title: Attenuation of paraquat-induced dopaminergic toxicity on the substantia nigra by (-)-deprenyl in vivo.

Journal: Toxicology and applied pharmacology20010401

Title: Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole.

Journal: European journal of clinical pharmacology20010401

Title: Deprenyl stimulates the efflux of monoamines from the rat hypothalamus in vitro.

Journal: Brain research bulletin20010401

Title: Do antioxidant strategies work against aging and age-associated disorders? Propargylamines: a possible antioxidant strategy.

Journal: Annals of the New York Academy of Sciences20010401

Title: Substrate and inhibitor specificities for human monoamine oxidase A and B are influenced by a single amino acid.

Journal: The Journal of biological chemistry20010330

Title: L-dopa and selegiline for tyrosine hydroxylase deficiency.

Journal: The Journal of pediatrics20010301

Title: Parkinson's disease therapy: treatment of early and late disease.

Journal: Chinese medical journal20010301

Title: Eldepryl prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigral neuronal apoptosis in mice.

Journal: Chinese medical journal20010301

Title: SKF-38393, a dopamine receptor agonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity.

Journal: Brain research20010223

Title: Selective inhibition of amine oxidases differently potentiate the hypophagic effect of benzylamine in mice.

Journal: European journal of pharmacology20010209

Title: Selegiline combined with enriched-environment housing attenuates spatial learning deficits following focal cerebral ischemia in rats.

Journal: Experimental neurology20010201

Title: The economic consequences of a drug-drug interaction.

Journal: Journal of clinical psychopharmacology20010201

Title: Enhancement of central nervous system pathology in early simian immunodeficiency virus infection by dopaminergic drugs.

Journal: Acta neuropathologica20010201

Title: Possible applications for dopaminergic agents following traumatic brain injury: part 2.

Journal: The Journal of head trauma rehabilitation20010201

Title: Selegiline completely restores choline acetyltransferase activity deficits in simian immunodeficiency infection.

Journal: European journal of pharmacology20010105

Title: Different sensitivity of mitochondrial and cytosolic monoamine oxidases to in vivo but not in vitro inhibition by specific irreversible inhibitors.

Journal: Medical science monitor : international medical journal of experimental and clinical research20010101

Title: Anti-apoptotic and apoptotic action of (-)-deprenyl and its metabolites.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101

Title: Freezing of gait in patients with advanced Parkinson's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101

Title: Long-term persistence of symptomatic effect of selegiline in Parkinson's disease. A two-months placebo-controlled withdrawal study.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101

Title: Biphasic effects of selegiline on striatal dopamine: lack of effect on methamphetamine-induced dopamine depletion.

Journal: Neurochemical research20010101

Title: [Current strategies of pathogenetic therapy of Alzheimer's disease].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk20010101

Title: Effect of longevity treatment with (-)deprenyl on lifespan and sexual behavior in female rats.

Journal: Neurobiology (Budapest, Hungary)20010101

Title: Antiaging compounds: (-)deprenyl (selegeline) and (-)1-(benzofuran-2-yl)-2-propylaminopentane, [(-)BPAP], a selective highly potent enhancer of the impulse propagation mediated release of catecholamine and serotonin in the brain.

Journal: CNS drug reviews20010101

Title: Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101

Title: [The effect of selegiline and vitamin E in the treatment of ALS: an open randomized clinical trials].

Journal: Neurologia i neurochirurgia polska20010101

Title: The effect of low oral doses of (-)-deprenyl and its metabolites on DSP-4 toxicity.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101

Title: Pharmacological options for the treatment of Tourette's disorder.

Journal: Drugs20010101

Title: Selegiline treatment facilitates recovery after stroke.

Journal: Neurorehabilitation and neural repair20010101

Title: A noncomparative open-label study evaluating the effect of selegiline hydrochloride in a clinical setting.

Journal: Veterinary therapeutics : research in applied veterinary medicine20010101

Title: [Dopaminergic agonists in the treatment of Parkinson's disease].

Journal: Revue medicale de Bruxelles20001201

Title: Antioxidant activity of the monoamine oxidase B inhibitor lazabemide.

Journal: Biochemical pharmacology20000901

Title: A hypertensive reaction induced by concurrent use of selegiline and dopamine.

Journal: The Annals of pharmacotherapy20000901

Title: Adverse drug reactions to selegiline: a review of the French pharmacovigilance database.

Journal: Clinical neuropharmacology20000101

Title: The novel type B MAO inhibitor PF9601N enhances the duration of L-DOPA-induced contralateral turning in 6-hydroxydopamine lesioned rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20000101

Title: Deterioration of parkinsonian symptoms following treatment of dopaminergic hallucinosis with olanzapine.

Journal: European psychiatry : the journal of the Association of European Psychiatrists19991001

Title: Effect of selegiline on cognitive functions in Parkinson's disease.

Journal: The Journal of the Association of Physicians of India19990801

Title: Selegiline effects on cocaine-induced changes in medial temporal lobe metabolism and subjective ratings of euphoria.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology19990601

Title: Selegiline-induced postural hypotension in Parkinson's disease: a longitudinal study on the effects of drug withdrawal.

Journal: Movement disorders : official journal of the Movement Disorder Society19990301

Title: Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline).

Journal: Journal of neural transmission. Supplementum19980101

Title: Experience with tranylcypromine in early Parkinson's disease.

Journal: Journal of neural transmission. Supplementum19980101

Title: Autonomic effects of selegiline: possible cardiovascular toxicity in Parkinson's disease.

Journal: Journal of neurology, neurosurgery, and psychiatry19970801

Title: The anticonvulsant effect of deprenyl on pentylenetetrazol-induced seizures in Lewis rats.

Journal: The International journal of neuroscience19970801

Title: Venlafaxine, monoamine oxidase inhibitors, and the serotonin syndrome.

Journal: Journal of clinical psychopharmacology19970201

Title: Absence of acute cocaine interactions with the MAO-B inhibitor selegiline.

Journal: Drug and alcohol dependence19950701

Title: Pharmacokinetic aspects of l-deprenyl (selegiline) and its metabolites.

Journal: Clinical pharmacology and therapeutics19941201

Title: The MAO-B inhibitor deprenyl, but not the MAO-A inhibitor clorgyline, potentiates the neurotoxicity of p-chloroamphetamine.

Journal: Brain research19940711

Title: Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease: the degree and reversibility of human brain MAO B inhibition by Ro 19 6327.

Journal: Neurology19931001

Title: End-of-dose dystonia in Parkinson's disease.

Journal: Neurology19931001

Title: Deprenyl in attention deficit associated with Tourette's syndrome.

Journal: Archives of neurology19930301

Title: Pseudophaeochromocytoma in parkinsonian patient treated with fluoxetine plus selegiline.

Journal: Lancet (London, England)19930227

Title: Selegiline and manic behavior in Parkinson's disease.

Journal: Archives of neurology19921201

Title: In vivo and in vitro pharmacologic profile of two new irreversible MAO-B inhibitors: MDL 72,974A and fluorodeprenyl.

Journal: Annals of the New York Academy of Sciences19920511

Title: Deprenyl effects on levodopa pharmacodynamics, mood, and free radical scavenging.

Journal: Neurology19920301

Title: Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons.

Journal: The Journal of pharmacology and experimental therapeutics19911101

Title: Improvement of cognitive function by MAO-B inhibitor L-deprenyl in aged rats.

Journal: Pharmacology, biochemistry, and behavior19910601

Title: A review of the pharmacology of selegiline.

Journal: Acta neurologica Scandinavica. Supplementum19910101

Title: Evaluation of the effects of inhibition of monoamine oxidase and senescence on methamphetamine-induced neuronal damage.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience19910101

Title: Ro 19-6327, a reversible and highly selective monoamine, oxidase B inhibitor: a novel tool to explore the MAO-B function in humans.

Journal: Advances in neurology19900101

Title: The effect of deprenyl (selegiline) on the natural history of Parkinson's disease.

Journal: Science (New York, N.Y.)19890804

Title: A possible L-deprenyl induced hypertensive reaction.

Journal: Journal of clinical psychopharmacology19890801

Title: Potentiation of central effects of L-dopa by an inhibitor of catechol-O-methyltransferase.

Journal: Journal of neural transmission19870101

Title: SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.

Journal: The Journal of pharmacology and experimental therapeutics19870101

Title: Pharmacokinetic aspects of deprenyl effects.

Journal: Polish journal of pharmacology and pharmacy19840101

Title: Brain monoamine oxidase in suckling rabbits treated with organophosphorus compound. I. Acute intoxication.

Journal: Acta physiologica Polonica19840101

Title: Deprenyl (selegiline) in combination treatment of Parkinson's disease.

Journal: Acta neurologica Scandinavica. Supplementum19830101

Title: The nature of the inhibition of rat liver monoamine oxidase types A and B by the acetylenic inhibitors clorgyline, l-deprenyl and pargyline.

Journal: Biochemical pharmacology19821115

Title: Inhibition of rabbit liver monoamine oxidase by nitro aromatic compounds.

Journal: Biochemical pharmacology19820815

Title: Oscillations in performance in levodopa-treated parkinsonians: treatment with bromocriptine and L-deprenyl.

Journal: Clinical and experimental neurology19790101

Building Blocks More >
1464-44-4
1464-44-4
Phenyl-beta-d-glucopyranoside
AA001DWB | MFCD00064089
146767-63-7
146767-63-7
1H-Pyrrolo[3,2-b]pyridine-5-carbonitrile
AA001E8G | MFCD09909831
147118-28-3
147118-28-3
Ethyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonyl)pyrimidine-5-carboxylate
AA001EJ0 | MFCD09840589
147465-50-7
147465-50-7
(4-Benzyl-morpholin-2-ylmethyl)-diethyl-amine
AA001EUF | MFCD06658342
147769-93-5
147769-93-5
(S)-3-Methyl-1-(2-piperidin-1-ylphenyl)butylamine
AA001F3U | MFCD03839861
1481-57-8
1481-57-8
1,2-Dibromo-4,5-difluoro-3-nitrobenzene
AA001FDL | MFCD11226312
141-78-6
141-78-6
Acetic acid ethyl ester
AA001FNJ | MFCD00009171
141454-65-1
141454-65-1
1-(3,5-Dichloropyridin-2-yl)ethanone
AA001GCQ | MFCD15526707
1416438-78-2
1416438-78-2
Spiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'h)-one
AA001GPO | MFCD22690069
1418117-82-4
1418117-82-4
7-Methoxyquinoline hydrochloride
AA001H59 | MFCD22683321
Submit
© 2017 AA BLOCKS, INC. All rights reserved.