Catalog No.:AA001HJK

1420477-60-6 | Acalabrutinib

Name: Name:Acalabrutinib
Brand: AABLOCKS
SKU: AA001HJK
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

1mg

98%

in stock

$6.00 $4.00

- +

2mg

98%

in stock

$7.00 $5.00

- +

100mg

98%

in stock

$15.00 $11.00

- +

98%

in stock

$65.00 $46.00

- +

Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA001HJK

Chemical Name:

Acalabrutinib

CAS Number:

1420477-60-6

Molecular Formula:

C26H23N7O2

Molecular Weight:

465.5065

MDL Number:

MFCD29472294

SMILES:

CC#CC(=O)N1CCC[C@H]1c1nc(c2n1ccnc2N)c1ccc(cc1)C(=O)Nc1ccccn1

Properties

Computed Properties

Complexity:

845

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

Literature

Title: Mantle Cell Lymphoma.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20160410

Title: Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.

Journal: The New England journal of medicine 20160128

Title: Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor.

Journal: Journal of hematology & oncology 20160101

Title: Wu J, et al. Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor. J Hematol Oncol. 2016 Mar 9;9:21

Title: Herman SE, et al. The Bruton's tyrosine kinase (BTK) inhibitor acalabrutinib demonstrates potent on-target effects and efficacy in two mouse models of chronic lymphocytic leukemia. Clin Cancer Res. 2016 Nov 30

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