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14919-49-4,MFCD00017690
Catalog No.:AA001LD8

14919-49-4 | 3,4'-Dihydroxyflavone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
>97.0%(GC)
in stock  
$92.00   $64.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001LD8
Chemical Name:
3,4'-Dihydroxyflavone
CAS Number:
14919-49-4
Molecular Formula:
C15H10O4
Molecular Weight:
254.2375
MDL Number:
MFCD00017690
SMILES:
Oc1ccc(cc1)c1oc2ccccc2c(=O)c1O
Properties
Properties
 
Form:
Solid  
MP:
275-276°C  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
393  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3  

Downstream Synthesis Route

[1]Sagrera,Gabriel;Seoane,Gustavo[Synthesis,2010,#16,p.2776-2786]

[2]Sobottka;Werner;Blaschke;Kiefer;Nowe;Dannhardt;Schapoval;Schenkel;Scriba[ArchivderPharmazie,2000,vol.333,#7,p.205-210]

14919-49-4    40542-90-3   
3,4'-di-(benzyloxycarhonylbutylcarbonyloxy)flavone 

[1]CurrentPatentAssignee:HOWARDFLOREYINSTITUTEAU-WO2006/94357,2006,A1Locationinpatent:Page/Pagecolumn34

Literature

Title: Design, synthesis and biological activity of flavonoid derivatives as selective agonists for neuromedin U 2 receptor.

Journal: Bioorganic & medicinal chemistry 20141101

Title: A novel relationship between the radical-scavenging activity of flavonoids and enthalpy of formation revealed with Hartree-Fock computations and thermochemical deduction.

Journal: Redox report : communications in free radical research 20120101

Title: 3,4-Dihydroxyflavone acts as an antioxidant and antiapoptotic agent to support bovine embryo development in vitro.

Journal: The Journal of reproduction and development 20110201

Title: Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

Journal: Molecular pharmaceutics 20100607

Title: Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity.

Journal: Journal of medicinal chemistry 20080327

Title: The anti-apoptotic and anti-oxidant effect of eriodictyol on UV-induced apoptosis in keratinocytes.

Journal: Biological & pharmaceutical bulletin 20070101

Title: Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids.

Journal: The Journal of biological chemistry 20050909

Title: Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6.

Quotation Request
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SDS
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Tags:14919-49-4 Molecular Formula|14919-49-4 MDL|14919-49-4 SMILES|14919-49-4 3,4'-Dihydroxyflavone
Catalog No.: AA001LD8
14919-49-4,MFCD00017690
14919-49-4 | 3,4'-Dihydroxyflavone
Pack Size： 1g
Purity： >97.0%(GC)
in stock
$92.00 $64.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA001LD8
Chemical Name: 3,4'-Dihydroxyflavone
CAS Number: 14919-49-4
Molecular Formula: C15H10O4
Molecular Weight: 254.2375
MDL Number: MFCD00017690
SMILES: Oc1ccc(cc1)c1oc2ccccc2c(=O)c1O
Properties
Form: Solid  
MP: 275-276°C  
Storage: Room Temperature;  
Complexity: 393  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 19  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3  
Downstream Synthesis Route
6889-78-7    14919-49-4 

[1]Sagrera,Gabriel;Seoane,Gustavo[Synthesis,2010,#16,p.2776-2786]

[2]Sobottka;Werner;Blaschke;Kiefer;Nowe;Dannhardt;Schapoval;Schenkel;Scriba[ArchivderPharmazie,2000,vol.333,#7,p.205-210]

14919-49-4    40542-90-3   
3,4'-di-(benzyloxycarhonylbutylcarbonyloxy)flavone 

[1]CurrentPatentAssignee:HOWARDFLOREYINSTITUTEAU-WO2006/94357,2006,A1Locationinpatent:Page/Pagecolumn34

Literature fold

Title: Design, synthesis and biological activity of flavonoid derivatives as selective agonists for neuromedin U 2 receptor.

Journal: Bioorganic & medicinal chemistry20141101

Title: A novel relationship between the radical-scavenging activity of flavonoids and enthalpy of formation revealed with Hartree-Fock computations and thermochemical deduction.

Journal: Redox report : communications in free radical research20120101

Title: 3,4-Dihydroxyflavone acts as an antioxidant and antiapoptotic agent to support bovine embryo development in vitro.

Journal: The Journal of reproduction and development20110201

Title: Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

Journal: Molecular pharmaceutics20100607

Title: Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity.

Journal: Journal of medicinal chemistry20080327

Title: The anti-apoptotic and anti-oxidant effect of eriodictyol on UV-induced apoptosis in keratinocytes.

Journal: Biological & pharmaceutical bulletin20070101

Title: Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids.

Journal: The Journal of biological chemistry20050909

Title: Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6.

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