Title: Sigma-1 receptor function is critical for both the discriminative stimulus and aversive effects of the kappa-opioid receptor agonist U-50488H.
Journal: Addiction biology20120701
Title: Evaluation of sigma (σ) receptors in the antidepressant-like effects of ketamine in vitro and in vivo.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20120401
Title: Distinct cardioprotective effects of 17β-estradiol and dehydroepiandrosterone on pressure overload-induced hypertrophy in ovariectomized female rats.
Journal: Menopause (New York, N.Y.)20111201
Title: Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.
Journal: The Journal of pharmacology and experimental therapeutics20111101
Title: Chloroquine inhibits glutamate-induced death of a neuronal cell line by reducing reactive oxygen species through sigma-1 receptor.
Journal: Journal of neurochemistry20111101
Title: Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity.
Journal: Bioorganic & medicinal chemistry letters20110615
Title: Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.
Journal: Journal of neurochemistry20110601
Title: Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.
Journal: European journal of pharmacology20110115
Title: Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions.
Journal: Expert opinion on therapeutic targets20101001
Title: Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist.
Journal: Psychopharmacology20090801
Title: Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent subchronic administration of donepezil: role of sigma-1 receptors.
Journal: Brain research20090707
Title: Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice.
Journal: Pain20090601
Title: Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by donepezil: role of sigma-1 receptors and IP3 receptors.
Journal: Progress in neuro-psychopharmacology & biological psychiatry20081001
Title: Dual DAT/sigma1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropan-1-ol.
Journal: Bioorganic & medicinal chemistry letters20081001
Title: Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: role of sigma-1 receptors.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20070301
Title: Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.
Journal: Journal of psychopharmacology (Oxford, England)20070101
Title: Dehydroepiandrosterone sulfate prevents ischemia-induced impairment of long-term potentiation in rat hippocampal CA1 by up-regulating tyrosine phosphorylation of NMDA receptor.
Journal: Neuropharmacology20061001
Title: A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors.
Journal: European journal of pharmacology20060424
Title: Differences in the allosteric modulation by phenytoin of the binding properties of the sigma1 ligands [3H](+)-pentazocine and [3H]NE-100.
Journal: Synapse (New York, N.Y.)20060301
Title: Chronic administration of dehydroepiandrosterone sulfate (DHEAS) primes for facilitated induction of long-term potentiation via sigma 1 (sigma1) receptor: optical imaging study in rat hippocampal slices.
Journal: Neuropharmacology20060301
Title: Sigma receptor ligands protect human retinal cells against oxidative stress.
Journal: Neuroreport20060227
Title: Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model.
Journal: Current drug metabolism20060201
Title: Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
Journal: BMC neuroscience20060101
Title: Improvement of memory impairment by (+)- and (-)-pentazocine via sigma, but not kappa opioid receptors.
Journal: Brain research20050928
Title: Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity.
Journal: Neuroreport20050801
Title: Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models.
Journal: Xenobiotica; the fate of foreign compounds in biological systems20050601
Title: Pharmacological characterization of the ameliorating effect on short-term memory impairment and antinociceptive effect of KT-90 in mice.
Journal: Behavioural brain research20050528
Title: Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Journal: Synapse (New York, N.Y.)20050301
Title: Distinct modulatory roles of sigma receptor subtypes on glutamatergic responses in the dorsal hippocampus.
Journal: Synapse (New York, N.Y.)20050101
Title: Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20040801
Title: Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
Journal: The Journal of endocrinology20040701
Title: Prediction of differences in in vivo oral clearance of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl] ethylamine monohydrochloride (NE-100) between extensive and poor metabolizers from in vitro metabolic data in human liver microsomes lacking CYP2D6 activity and recombinant CYPs.
Journal: Xenobiotica; the fate of foreign compounds in biological systems20040701
Title: Protein kinase C-dependent potentiation of intracellular calcium influx by sigma1 receptor agonists in rat hippocampal neurons.
Journal: The Journal of pharmacology and experimental therapeutics20031101
Title: Differences in cytochrome P450 forms involved in the metabolism of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a novel sigma ligand, in human liver and intestine.
Journal: Drug metabolism and disposition: the biological fate of chemicals20030101
Title: Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate).
Journal: The Journal of pharmacology and experimental therapeutics20020401
Title: Neurosteroids stimulate G protein-coupled sigma receptors in mouse brain synaptic membrane.
Journal: Neuroscience research20010901
Title: Multiple pathways of sigma(1) receptor ligand uptakes into primary cultured neuronal cells.
Journal: European journal of pharmacology20010803
Title: Effects of a novel, selective, sigma1-ligand, MS-377, on phencyclidine-induced behaviour.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20010701
Title: Effects of a methanolic extract and a hyperforin-enriched CO2 extract of Hypericum perforatum on alcohol intake in rats.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire)20010101
Title: Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference.
Journal: Neuroreport20000911
Title: NE-100, a novel sigma receptor ligand: in vivo tests.
Journal: Life sciences19930101
