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Title: Novel vesicular and particulate drug delivery systems for topical treatment of acne.
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Title: (1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.
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Title: Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production.
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Title: Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptake.
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Journal: Journal of medicinal chemistry 20050224
Title: Synthesis and structure-activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands.
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Title: A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From British Journal of Dermatology (1997), 137(5), 699-702.
Title: Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch?fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12.
Title: Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60.
Title: Blaschke T, Kankate L, Kramer KD.Structure and dynamics of drug-carrier systems as studied by parelectric spectroscopy.Adv Drug Deliv Rev. 2007 Jul 10;59(6):403-10. Epub 2007 May 3.
Title: Matias JR, Gaillard M.Local inhibition of sebaceous gland growth by topically applied RU 58841.Ann N Y Acad Sci. 1995 Jun 12;761:56-65.