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156223-05-1,MFCD00941364
Catalog No.:AA001OIY

156223-05-1 | GTS-21 dihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$19.00   $14.00
- +
5mg
98+%
in stock  
$47.00   $33.00
- +
10mg
98+%
in stock  
$70.00   $49.00
- +
25mg
98+%
in stock  
$117.00   $82.00
- +
50mg
98+%
in stock  
$198.00   $139.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001OIY
Chemical Name:
GTS-21 dihydrochloride
CAS Number:
156223-05-1
Molecular Formula:
C19H20N2O2
Molecular Weight:
308.3743
MDL Number:
MFCD00941364
SMILES:
COc1cc(OC)ccc1/C=C/1\CCCN=C1c1cccnc1
Properties

Downstream Synthesis Route

[1]Kem,WilliamR.;Mahnir,VladimirM.;Prokai,Laszlo;Papke,RogerL.;Cao,Xuefang;LeFrancois,Susan;Wildeboer,Kristin;Prokai-Tatrai,Katalin;Porter-Papke,Julia;Soti,Ferenc[MolecularPharmacology,2004,vol.65,#1,p.56-67]

[2]Zoltewicz,JohnA.;Prokai-Tetrai,Katalin;Bloom,LindaB.[Heterocycles,1993,vol.35,#1,p.171-180]

Literature

Title: Briggs CA, et al. Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacol Biochem Behav. 1997;57(1-2):231-241.

Title: Zhang R, et al. N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. J Pharmacol Exp Ther. 2006;317(3):1276-1284.

Title: Mei Z, et al. α7 nAchR agonist GTS 21 reduces radiation induced lung injury. Oncol Rep. 2018;40(4):2287-2297.

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SDS
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