Home Fluorides 1649-18-9
1649-18-9,MFCD00866692
Catalog No.:AA001V26

1649-18-9 | 1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-

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25mg
98%(HPLC)
in stock  
$34.00   $24.00
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100mg
98%(HPLC)
in stock  
$102.00   $72.00
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500mg
98%(HPLC)
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$305.00   $214.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001V26
Chemical Name:
1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-
CAS Number:
1649-18-9
Molecular Formula:
C19H22FN3O
Molecular Weight:
327.3959
MDL Number:
MFCD00866692
SMILES:
Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccccn1
Properties
Computed Properties
 
Complexity:
390  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
6  
XLogP3:
3.3  

Literature

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Title: Impact of general injection anaesthesia and analgesia on post-castration behaviour and teat order of piglets.

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Title: Anaesthetic complications in pigs undergoing MRI guided convection enhanced drug delivery to the brain: a case series.

Journal: Veterinary anaesthesia and analgesia 20121101

Title: Post-farrowing stress management in sows by administration of azaperone: effects on piglets performance.

Journal: Journal of animal science 20120701

Title: Combinational spinal GAD65 gene delivery and systemic GABA-mimetic treatment for modulation of spasticity.

Journal: PloS one 20120101

Title: Intrauterine growth retarded progeny of pregnant sows fed high protein:low carbohydrate diet is related to metabolic energy deficit.

Journal: PloS one 20120101

Title: Towards real-time cardiovascular magnetic resonance guided transarterial CoreValve implantation: in vivo evaluation in swine.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20120101

Title: Oversized vein grafts develop advanced atherosclerosis in hypercholesterolemic minipigs.

Journal: BMC cardiovascular disorders 20120101

Title: Early developing pig embryos mediate their own environment in the maternal tract.

Journal: PloS one 20120101

Title: [Evaluation of perioperative analgesia by nociceptive flexor reflex in pigs under ketamine-azaperone-general anaesthesia].

Journal: Berliner und Munchener tierarztliche Wochenschrift 20120101

Title: Home on the range: factors explaining partial migration of African buffalo in a tropical environment.

Journal: PloS one 20120101

Title: Alveolar overdistension as a cause of lung injury: differences among three animal species.

Journal: TheScientificWorldJournal 20120101

Title: The effects of succinylcholine or low-dose rocuronium to aid endotracheal intubation of adult sows.

Journal: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20120101

Title: Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study.

Journal: Basic research in cardiology 20111101

Title: Emotionality in growing pigs: is the open field a valid test?

Journal: Physiology & behavior 20111024

Title: Multidetector computed tomographic angiography evaluation of micropig major systemic vessels for xenotransplantation.

Journal: Journal of veterinary science 20110901

Title: AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

Journal: Gene therapy 20110701

Title: Tissue damage with different surgical techniques in a porcine model of liver resection: implications for living-donor liver transplantation?

Journal: Journal of hepato-biliary-pancreatic sciences 20110501

Title: [Piglet castration using injection anesthesia: experiences with a combination of azaperone, butorphanol and ketamine].

Journal: Schweizer Archiv fur Tierheilkunde 20110101

Title: Experimental trauma models: an update.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway.

Journal: BMC cardiovascular disorders 20110101

Title: Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

Journal: Molecular systems biology 20110101

Title: A simple dummy liver assist device prolongs anhepatic survival in a porcine model of total hepatectomy by slight hypothermia.

Journal: BMC gastroenterology 20110101

Title: Subcoronary versus supracoronary aortic stenosis. An experimental evaluation.

Journal: Journal of cardiothoracic surgery 20110101

Title: Tolerability of inhaled N-chlorotaurine in an acute pig streptococcal lower airway inflammation model.

Journal: BMC infectious diseases 20110101

Title: Pharmacological postconditioning with sevoflurane after cardiopulmonary resuscitation reduces myocardial dysfunction.

Journal: Critical care (London, England) 20110101

Title: RPE and neuronal differentiation of allotransplantated porcine ciliary epithelium-derived cells.

Journal: Molecular vision 20110101

Title: Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model.

Journal: British journal of anaesthesia 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: 64-channel multi-detector row CT angiographic evaluation of the micropigs for potential living donor lung transplantation.

Journal: Journal of veterinary science 20100901

Title: Enhanced blood pressure and appetite responses to chronic central melanocortin-3/4 receptor blockade in dietary-induced obesity.

Journal: Journal of hypertension 20100701

Title: Haloperidol and azaperone in drive-net captured Southern chamois (Rupicapra pyrenaica).

Journal: Journal of wildlife diseases 20100701

Title: Low plasma potassium in deep hypothermic cardiac arrest indicates that cardiac arrest is secondary to hypothermia: a porcine study.

Journal: European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20100601

Title: Use of haloperidol and azaperone for stress control in roe deer (Capreolus capreolus) captured by means of drive-nets.

Journal: Research in veterinary science 20100601

Title: Preclinical electrogastrography in experimental pigs.

Journal: Interdisciplinary toxicology 20100601

Title: Minimum alveolar concentrations and hemodynamic effects of two different preparations of sevoflurane in pigs.

Journal: Clinics (Sao Paulo, Brazil) 20100501

Title: Holmium-166 poly(L-lactic acid) microsphere radioembolisation of the liver: technical aspects studied in a large animal model.

Journal: European radiology 20100401

Title: Wireless video capsule enteroscopy in preclinical studies: methodical design of its applicability in experimental pigs.

Journal: Digestive diseases and sciences 20100301

Title: Multidetector row computed tomography evaluation of the micropig kidney as a potential renal donor.

Journal: Journal of veterinary science 20100301

Title: Apyrase treatment of myocardial infarction according to a clinically applicable protocol fails to reduce myocardial injury in a porcine model.

Journal: BMC cardiovascular disorders 20100101

Title: Acid-base balance and ventilation during sternal and lateral recumbency in field immobilized black rhinoceros (Diceros bicornis) receiving oxygen insufflation: a preliminary report.

Journal: Journal of wildlife diseases 20100101

Title: Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs.

Journal: PloS one 20100101

Title: Postmortem Evaluation of Left Flank Laparoscopic Access in an Adult Female Giraffe (Giraffa camelopardalis).

Journal: Veterinary medicine international 20100101

Title: Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures.

Journal: BMC gastroenterology 20100101

Title: Standardized intensive care unit management in an anhepatic pig model: new standards for analyzing liver support systems.

Journal: Critical care (London, England) 20100101

Title: The use of in vitro technologies coupled with high resolution accurate mass LC-MS for studying drug metabolism in equine drug surveillance.

Journal: Drug testing and analysis 20100101

Title: Anti- or profibrillatory effects of Na(+) channel blockade depend on the site of application relative to gradients in repolarization.

Journal: Frontiers in physiology 20100101

Title: Psychological interventions in the management of common skin conditions.

Journal: Psychology research and behavior management 20100101

Title: Resource efficiency and economic implications of alternatives to surgical castration without anaesthesia.

Journal: Animal : an international journal of animal bioscience 20091101

Title: Different solutions used for submucosal injection influenced early healing of gastric endoscopic mucosal resection in a preclinical study in experimental pigs.

Journal: Surgical endoscopy 20090901

Title: Rapid method for the determination of tranquilizers and a beta-blocker in porcine and bovine kidney by liquid chromatography with tandem mass spectrometry.

Journal: Analytica chimica acta 20090401

Title: Butorphanol-azaperone-medetomidine for immobilization of captive white-tailed deer.

Journal: Journal of wildlife diseases 20090401

Title: Butorphanol, azaperone, and medetomidine anesthesia in free-ranging white-tailed deer (Odocoileus virginianus) using radiotransmitter darts.

Journal: Journal of wildlife diseases 20090401

Title: Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model.

Journal: British journal of anaesthesia 20090301

Title: Comparison of azaperone-detomidine-butorphanol-ketamine and azaperone-tiletamine-zolazepam for anaesthesia in piglets.

Journal: Veterinary anaesthesia and analgesia 20090301

Title: Simultaneous determination of azaperone and azaperol in animal tissues by HPLC with confirmation by electrospray ionization mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

Title: Computer tomographic investigation of subcutaneous adipose tissue as an indicator of body composition.

Journal: Acta veterinaria Scandinavica 20090101

Title: [Determination of azaperone and carazolol residues in animals kidney using LC-MS/MS method].

Journal: Roczniki Panstwowego Zakladu Higieny 20090101

Title: Evaluation of intramuscular butorphanol, azaperone, and medetomidine and nasal oxygen insufflation for the chemical immobilization of white-tailed deer, Odocoileus virginianus.

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20080901

Title: Thermal, cardiorespiratory and cortisol responses of impala (Aepyceros melampus) to chemical immobilisation with 4 different drug combinations.

Journal: Journal of the South African Veterinary Association 20080901

Title: Comprehensive screening and quantification of veterinary drugs in milk using UPLC-ToF-MS.

Journal: Analytical and bioanalytical chemistry 20080701

Title: A novel method for transuterine identification of piglets.

Journal: Laboratory animals 20080701

Title: Immobilization of black bears (Ursus americanus) with a combination of butorphanol, azaperone, and medetomidine.

Journal: Journal of wildlife diseases 20080701

Title: Comparison of cardiac function and coronary angiography between conventional pigs and micropigs as measured by multidetector row computed tomography.

Journal: Journal of veterinary science 20080601

Title: Alveolar recruitment can be predicted from airway pressure-lung volume loops: an experimental study in a porcine acute lung injury model.

Journal: Critical care (London, England) 20080101

Title: Bioavailability of heme iron in biscuit filling using piglets as an animal model for humans.

Journal: International journal of biological sciences 20080101

Title: Does carbon monoxide treatment alter cytokine levels after endotoxin infusion in pigs? A randomized controlled study.

Journal: Journal of inflammation (London, England) 20080101

Title: Reliability of continuous cardiac output measurement during intra-abdominal hypertension relies on repeated calibrations: an experimental animal study.

Journal: Critical care (London, England) 20080101

Title: Successful treatment of a squamous cell carcinoma in a white rhinoceros, Ceratotherium simum.

Journal: Veterinary dermatology 20071201

Title: Anaesthesia for castration of piglets: comparison between intranasal and intramuscular application of ketamine, climazolam and azaperone.

Journal: Schweizer Archiv fur Tierheilkunde 20070901

Title: The cardiopulmonary effects of etorphine, azaperone, detomidine, and butorphanol in field-anesthetized white rhinoceroses (Ceratotherium simum).

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20070901

Title: Determination of residues of azaperone in the kidneys by liquid chromatography with fluorescence detection.

Journal: Analytica chimica acta 20070314

Title: Evaluation of the effects of the sedation with azaperone/acepromazine and immobilization with guaiphenesin/thiopentone in mules.

Journal: Veterinary research communications 20070201

Title: Mild hypothermia reduces cardiac post-ischemic reactive hyperemia.

Journal: BMC cardiovascular disorders 20070101

Title: Vasopressin improves survival in a porcine model of abdominal vascular injury.

Journal: Critical care (London, England) 20070101

Title: The litterbox blues.

Journal: Compendium (Yardley, PA) 20070101

Title: Changes in the relative thickness of individual subcutaneous adipose tissue layers in growing pigs.

Journal: Acta veterinaria Scandinavica 20070101

Title: Euthanasia of exotic pigs.

Journal: The Veterinary record 20060708

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: A comparison of transcranial Doppler with near infrared spectroscopy and indocyanine green during hemorrhagic shock: a prospective experimental study.

Journal: Critical care (London, England) 20060101

Title: Physiological routes from intra-uterine seminal contents to advancement of ovulation.

Journal: Acta veterinaria Scandinavica 20060101

Title: Gelatinases, endonuclease and Vascular Endothelial Growth Factor during development and regression of swine luteal tissue.

Journal: BMC developmental biology 20060101

Title: Use of buspirone and enrichment to manage aberrant behavior in an American badger (Taxidea taxus).

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20050901

Title: Placentation in the paca (Agouti paca L).

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Coronary artery reperfusion: The ADP receptor P2Y(1) mediates early reactive hyperemia in vivo in pigs.

Journal: Purinergic signalling 20041201

Title: A review of drugs and techniques used for sedation and anaesthesia in captive rhinoceros species.

Journal: Australian veterinary journal 20040901

Title: Severe hypoxaemia in field-anaesthetised white rhinoceros (Ceratotherium simum) and effects of using tracheal insufflation of oxygen.

Journal: Journal of the South African Veterinary Association 20040601

Title: Development of a rapid screening test for veterinary sedatives and the beta-blocker carazolol in porcine kidney by ELISA.

Journal: The Analyst 20040201

Title: Induction of anaesthesia in pigs using a new alphaxalone formulation.

Journal: The Veterinary record 20031115

Title: Provision of anaesthesia for porcine cardiac transplantation at the veterinary school in Trinidad and Tobago.

Journal: The West Indian medical journal 20030601

Title: Use of azaperone and zuclopenthixol acetate to facilitate translocation of white-tailed deer (Odocoileus virginianus).

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20020601

Title: Rectal prolapse associated with a healed pelvic fracture in a pregnant free-ranging African black rhinoceros (Diceros bicornis). Part 1: anaesthesia.

Journal: Journal of the South African Veterinary Association 20011201

Title: Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth.

Journal: Comparative medicine 20011001

Title: Chemical anesthesia of northern sea otters (Enhydra lutris): results of past field studies.

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20010601

Title: Comparison of extradural injections of lignocaine and xylazine in azaperone-sedated pigs.

Journal: Veterinary journal (London, England : 1997) 20010101

Title: Rapid brain cooling in intubated pigs through nasal flushing with oxygen: prevention of brain hyperthermia.

Journal: Acta veterinaria Scandinavica 20010101

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Tags:1649-18-9 Molecular Formula|1649-18-9 MDL|1649-18-9 SMILES|1649-18-9 1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-