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173897-44-4,MFCD16038860
Catalog No.:AA001Z73

173897-44-4 | Y-33075 dihydrochloride

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Purity
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Price(USD)
Quantity
  
5mg
97%
in stock  
$200.00   $140.00
- +
10mg
97%
in stock  
$299.00   $209.00
- +
100mg
98+%
in stock  
$357.00   $250.00
- +
250mg
98+%
in stock  
$535.00   $375.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001Z73
Chemical Name:
Y-33075 dihydrochloride
CAS Number:
173897-44-4
Molecular Formula:
C16H18Cl2N4O
Molecular Weight:
353.2463
MDL Number:
MFCD16038860
SMILES:
O=C(c1ccc(cc1)[C@H](N)C)Nc1ccnc2c1cc[nH]2.Cl.Cl
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION-EP1195372,2002,A1Locationinpatent:Page53

[2]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1Locationinpatent:Paragraph0076

173897-93-3   
CASUnavailable 
 
CASUnavailable 
  173897-44-4 

[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION-US5958944,1999,A

[2]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1

[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1

[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1

[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1

Literature

Title: Hideki Tokushige, et al. Effects of Topical Administration of Y-39983, a Selective Rho-Associated Protein Kinase Inhibitor, on Ocular Tissues in Rabbits and Monkeys Invest. Ophthalmol. Vis. Sci. July 2007 vol. 48no. 7 3216-3222

Title: Tokushige H, et al. Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats. Curr Eye Res. 2011 Oct;36(10):964-70.

Title: Watabe H, et al. Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries.Jpn J Ophthalmol. 2011 Jul;55(4):411-7. Epub 2011 Jun 11.

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SDS
Tags:173897-44-4 Molecular Formula|173897-44-4 MDL|173897-44-4 SMILES|173897-44-4 Y-33075 dihydrochloride