Title: Emerging migraine treatments and drug targets.
Journal: Trends in pharmacological sciences 20110601
Title: Design considerations in migraine with aura trials: learning from experience.
Journal: Cephalalgia : an international journal of headache 20100901
Title: On the methodology of drug trials in migraine with aura.
Journal: Cephalalgia : an international journal of headache 20100901
Title: Tonabersat: a cortical spreading depression inhibitor as potential pharmacologic prophylaxis in migraine with aura.
Journal: Current neurology and neuroscience reports 20100101
Title: Neurological mechanisms of migraine: potential of the gap-junction modulator tonabersat in prevention of migraine.
Journal: Cephalalgia : an international journal of headache 20091101
Title: Efficacy and safety of tonabersat, a gap-junction modulator, in the acute treatment of migraine: a double-blind, parallel-group, randomized study.
Journal: Cephalalgia : an international journal of headache 20091101
Title: Tonabersat, a gap-junction modulator: efficacy and safety in two randomized, placebo-controlled, dose-ranging studies of acute migraine.
Journal: Cephalalgia : an international journal of headache 20091101
Title: Tonabersat, a novel gap-junction modulator for the prevention of migraine.
Journal: Cephalalgia : an international journal of headache 20091101
Title: Effects of tonabersat on migraine with aura: a randomised, double-blind, placebo-controlled crossover study.
Journal: The Lancet. Neurology 20090801
Title: Tonabersat for migraine prevention: new life or last gasp?
Journal: The Lancet. Neurology 20090801
Title: Randomized, double-blind, placebo-controlled, proof-of-concept study of the cortical spreading depression inhibiting agent tonabersat in migraine prophylaxis.
Journal: Cephalalgia : an international journal of headache 20090701
Title: 2008: the year in review.
Journal: Headache 20090501
Title: Tonabersat inhibits trigeminal ganglion neuronal-satellite glial cell signaling.
Journal: Headache 20090101
Title: Emerging therapies for migraine.
Journal: Nature clinical practice. Neurology 20071101
Title: Recent advances in understanding migraine mechanisms, molecules and therapeutics.
Journal: Trends in molecular medicine 20070101
Title: Migraine headaches: a historical prospective, a glimpse into the future, and migraine epidemiology.
Journal: Disease-a-month : DM 20061001
Title: A double-blind study of SB-220453 (Tonerbasat) in the glyceryltrinitrate (GTN) model of migraine.
Journal: Cephalalgia : an international journal of headache 20041001
Title: A delayed class of BOLD waveforms associated with spreading depression in the feline cerebral cortex can be detected and characterised using independent component analysis (ICA).
Journal: Magnetic resonance imaging 20031101
Title: Diffusion-weighted MRI used to detect in vivo modulation of cortical spreading depression: comparison of sumatriptan and tonabersat.
Journal: Experimental neurology 20011201
Title: Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes.
Journal: British journal of pharmacology 20010401
Title: Cortical spreading depression produces increased cGMP levels in cortex and brain stem that is inhibited by tonabersat (SB-220453) but not sumatriptan.
Journal: Brain research 20010209
Title: Silberstein SD, et al. Tonabersat, a gap-junction modulator: efficacy and safety in two randomized, placebo-controlled, dose-ranging studies of acute migraine. Cephalalgia. 2009 Nov;29 Suppl 2:17-27.
Title: Chen Q, et al. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. Nature. 2016 May 18;533(7604):493-8.
Title: Kim Y, et al. Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels. Neurotherapeutics. 2017 May 30.