Home Amines 1758-80-1
1758-80-1,MFCD07368664
Catalog No.:AA00214O

1758-80-1 | Butanoic acid, 2,4-diamino-, (2S)-

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100mg
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$78.00   $54.00
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1g
98%
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$156.00   $109.00
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5g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00214O
Chemical Name:
Butanoic acid, 2,4-diamino-, (2S)-
CAS Number:
1758-80-1
Molecular Formula:
C4H10N2O2
Molecular Weight:
118.1344
MDL Number:
MFCD07368664
SMILES:
N[C@H](C(=O)O)CCN
Properties
Computed Properties
 
Complexity:
84.1  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
-4.6  

Literature

Title: Alpinimonas psychrophila gen. nov., sp. nov., an actinobacterium of the family Microbacteriaceae isolated from alpine glacier cryoconite.

Journal: International journal of systematic and evolutionary microbiology 20121101

Title: Selective LC-MS/MS method for the identification of BMAA from its isomers in biological samples.

Journal: Analytical and bioanalytical chemistry 20120601

Title: Leucobacter margaritiformis sp. nov., isolated from bamboo extract.

Journal: Current microbiology 20120501

Title: Elucidation of matrix effects and performance of solid-phase extraction for LC-MS/MS analysis of β-N-methylamino-L-alanine (BMAA) and 2,4-diaminobutyric acid (DAB) neurotoxins in cyanobacteria.

Journal: The Analyst 20120307

Title: The emerging science of BMAA: do cyanobacteria contribute to neurodegenerative disease?

Journal: Environmental health perspectives 20120301

Title: Role of histidine 225 in adenosylcobalamin-dependent ornithine 4,5-aminomutase.

Journal: Bioorganic chemistry 20120201

Title: Leucobacter denitrificans sp. nov., isolated from cow dung.

Journal: Journal of microbiology (Seoul, Korea) 20120201

Title: Herbiconiux moechotypicola sp. nov., a xylanolytic bacterium isolated from the gut of hairy long-horned toad beetles, Moechotypa diphysis (Pascoe).

Journal: International journal of systematic and evolutionary microbiology 20120101

Title: A comparative study on three analytical methods for the determination of the neurotoxin BMAA in cyanobacteria.

Journal: PloS one 20120101

Title: Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases.

Journal: ChemMedChem 20111104

Title: Leucobacter celer sp. nov., isolated from Korean fermented seafood.

Journal: International journal of systematic and evolutionary microbiology 20111001

Title: A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.

Journal: Environmental microbiology 20110801

Title: Modes of action of microbially-produced phytotoxins.

Journal: Toxins 20110801

Title: Agromyces flavus sp. nov., an actinomycete isolated from soil.

Journal: International journal of systematic and evolutionary microbiology 20110701

Title: Agromyces soli sp. nov., isolated from farm soil.

Journal: International journal of systematic and evolutionary microbiology 20110601

Title: Leucobacter chromiiresistens sp. nov., a chromate-resistant strain.

Journal: International journal of systematic and evolutionary microbiology 20110401

Title: Leucobacter salsicius sp. nov., from a salt-fermented food.

Journal: International journal of systematic and evolutionary microbiology 20110301

Title: From toxins targeting ligand gated ion channels to therapeutic molecules.

Journal: Toxins 20110301

Title: Amnibacterium kyonggiense gen. nov., sp. nov., a new member of the family Microbacteriaceae.

Journal: International journal of systematic and evolutionary microbiology 20110101

Title: Prominent human health impacts from several marine microbes: history, ecology, and public health implications.

Journal: International journal of microbiology 20110101

Title: Leucobacter aerolatus sp. nov., from the air of a duck barn.

Journal: International journal of systematic and evolutionary microbiology 20101201

Title: The cyanobacteria derived toxin Beta-N-methylamino-L-alanine and amyotrophic lateral sclerosis.

Journal: Toxins 20101201

Title: Distinguishing the cyanobacterial neurotoxin beta-N-methylamino-L-alanine (BMAA) from its structural isomer 2,4-diaminobutyric acid (2,4-DAB).

Journal: Toxicon : official journal of the International Society on Toxinology 20101101

Title: Agromyces bauzanensis sp. nov., isolated from soil.

Journal: International journal of systematic and evolutionary microbiology 20101001

Title: Agrococcus terreus sp. nov. and Micrococcus terreus sp. nov., isolated from forest soil.

Journal: International journal of systematic and evolutionary microbiology 20100801

Title: Agromyces atrinae sp. nov., isolated from fermented seafood.

Journal: International journal of systematic and evolutionary microbiology 20100501

Title: Cryobacterium roopkundense sp. nov., a psychrophilic bacterium isolated from glacial soil.

Journal: International journal of systematic and evolutionary microbiology 20100401

Title: Diastereo- and enantioselective synthesis of alpha,gamma-diaminobutyric acid derivatives via Cu-catalyzed asymmetric Michael reaction.

Journal: Organic letters 20100305

Title: LC-MS/MS determination of the isomeric neurotoxins BMAA (beta-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in cyanobacteria and seeds of Cycas revoluta and Lathyrus latifolius.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Leifsonia lichenia sp. nov., isolated from lichen in Japan.

Journal: The Journal of general and applied microbiology 20091001

Title: Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

Journal: Nature chemical biology 20090801

Title: Analysis of achromobactin biosynthesis by Pseudomonas syringae pv. syringae B728a.

Journal: Journal of bacteriology 20090701

Title: Description of Leifsonia kafniensis sp. nov. and Leifsonia antarctica sp. nov.

Journal: International journal of systematic and evolutionary microbiology 20090601

Title: Leucobacter chironomi sp. nov., a chromate-resistant bacterium isolated from a chironomid egg mass.

Journal: International journal of systematic and evolutionary microbiology 20090401

Title: AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis.

Journal: Nature chemical biology 20090301

Title: Glaciibacter superstes gen. nov., sp. nov., a novel member of the family Microbacteriaceae isolated from a permafrost ice wedge.

Journal: International journal of systematic and evolutionary microbiology 20090301

Title: Presence of the neurotoxic amino acids beta-N-methylamino-L-alanine (BMAA) and 2,4-diamino-butyric acid (DAB) in shallow springs from the Gobi Desert.

Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101

Title: Cyanobacteria and BMAA exposure from desert dust: a possible link to sporadic ALS among Gulf War veterans.

Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101

Title: Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase.

Journal: The Journal of biological chemistry 20081212

Title: Agrococcus versicolor sp. nov., an actinobacterium associated with the phyllosphere of potato plants.

Journal: International journal of systematic and evolutionary microbiology 20081201

Title: Leucobacter tardus sp. nov., isolated from the phyllosphere of Solanum tuberosum L.

Journal: International journal of systematic and evolutionary microbiology 20081101

Title: Agrococcus jejuensis sp. nov., isolated from dried seaweed.

Journal: International journal of systematic and evolutionary microbiology 20081001

Title: Schumannella luteola gen. nov., sp. nov., a novel genus of the family Microbacteriaceae.

Journal: The Journal of general and applied microbiology 20081001

Title: Leifsonia pindariensis sp. nov., isolated from the Pindari glacier of the Indian Himalayas, and emended description of the genus Leifsonia.

Journal: International journal of systematic and evolutionary microbiology 20080901

Title: Frigoribacterium mesophilum sp. nov., a mesophilic actinobacterium isolated from Bigeum Island, Korea.

Journal: International journal of systematic and evolutionary microbiology 20080801

Title: Cryobacterium mesophilum sp. nov., a novel mesophilic bacterium.

Journal: International journal of systematic and evolutionary microbiology 20080501

Title: Humibacter albus gen. nov., sp. nov., isolated from sewage sludge compost.

Journal: International journal of systematic and evolutionary microbiology 20080401

Title: Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck.

Journal: Saline systems 20080101

Title: Leucobacter chromiireducens subsp. solipictus subsp. nov., a pigmented bacterium isolated from the nematode Caenorhabditis elegans, and emended description of L. chromiireducens.

Journal: International journal of systematic and evolutionary microbiology 20071201

Title: Alpha-diaminobutyric acid-linked hairpin polyamides.

Journal: Bioorganic & medicinal chemistry 20071115

Title: Antitumor effects of the MIG and IP-10 genes transferred with poly [D,L-2,4-diaminobutyric acid] on murine neuroblastoma.

Journal: Cancer gene therapy 20070801

Title: Chiroptical properties of diamino carboxylic acids.

Journal: Chirality 20070701

Title: Cryobacterium psychrotolerans sp. nov., a novel psychrotolerant bacterium isolated from the China No. 1 glacier.

Journal: International journal of systematic and evolutionary microbiology 20070401

Title: Leifsonia ginsengi sp. nov., isolated from ginseng root.

Journal: International journal of systematic and evolutionary microbiology 20070201

Title: Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2, 4 diaminobutyric acid (DAB).

Journal: Journal of neuro-oncology 20061201

Title: Synthesis, characterization and hybridization studies of new nucleo-gamma-peptides based on diaminobutyric acid.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20061201

Title: Base pair recognition of the stereochemically alpha-substituted gamma-turn of pyrrole/imidazole hairpin polyamides.

Journal: Journal of the American Chemical Society 20061122

Title: Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the halotolerant methanotroph Methylomicrobium alcaliphilum 20Z.

Journal: Biochemistry. Biokhimiia 20050801

Title: Phosphorylation-driven protein-protein interactions: a protein kinase sensing system.

Journal: Journal of the American Chemical Society 20050601

Title: Nature's protection racket.

Journal: Chemistry & biology 20050601

Title: Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway.

Journal: Chemistry & biology 20050601

Title: GABAergic modulation of motor-driven behaviors in juvenile Drosophila and evidence for a nonbehavioral role for GABA transport.

Journal: Journal of neurobiology 20041101

Title: A new class of foldamers based on cis-gamma-amino-L-proline.

Journal: Journal of the American Chemical Society 20040519

Title: Effective transfer of interleukin-12 gene to solid tumors using a novel gene delivery system, poly [D,L-2,4-diaminobutyric acid].

Journal: Cancer gene therapy 20040201

Title: Platinum complexes of diaminocarboxylic acids and their ethyl ester derivatives: the effect of the chelate ring size on antitumor activity and interactions with GMP and DNA.

Journal: Journal of inorganic biochemistry 20030901

Title: Unique antitumour effects of L-2,4 diaminobutyric acid on cultured hepatoma cells.

Journal: Anticancer research 20030101

Title: Diversity of grass-associated Microbacteriaceae isolated from the phyllosphere and litter layer after mulching the sward; polyphasic characterization of Subtercola pratensis sp. nov., Curtobacterium herbarum sp. nov. and Plantibacter flavus gen. nov., sp. nov.

Journal: International journal of systematic and evolutionary microbiology 20020901

Title: Conformational studies of cyclic enkephalin analogues with L- or D-proline in position 3.

Journal: Biopolymers 20020405

Title: Does extracellular calcium determine what pool of GABA is the target for alpha-latrotoxin?

Journal: Neurochemistry international 20020401

Title: Topography of the neurotensin (NT)(8-9) binding site of human NT receptor-1 probed with NT(8-13) analogs.

Journal: The journal of peptide research : official journal of the American Peptide Society 20020201

Title: Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.

Journal: Journal of molecular biology 20020111

Title: Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1.

Journal: British journal of pharmacology 20020101

Title: [Effect of synaptosomal cytosolic [3H]GABA pool depletion on secretory ability of alpha-latrotoxin].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101

Title: Novel spermine-amino acid conjugates and basic tripeptides enhance cleavage of the hairpin ribozyme at low magnesium ion concentration.

Journal: Bioorganic & medicinal chemistry letters 20011203

Title: Agreia bicolorata gen. nov., sp. nov., to accommodate actinobacteria isolated from narrow reed grass infected by the nematode Heteroanguina graminophila.

Journal: International journal of systematic and evolutionary microbiology 20011101

Title: Agromyces luteolus sp. nov., Agromyces rhizospherae sp. nov. and Agromyces bracchium sp. nov., from the mangrove rhizosphere.

Journal: International journal of systematic and evolutionary microbiology 20010701

Title: Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase.

Journal: Journal of enzyme inhibition 20010101

Title: Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.

Journal: General pharmacology 19990301

Title: Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.

Journal: Biochemical pharmacology 19931214

Title: Effects of some GABAergic agents on quinine-induced seizures in mice.

Journal: Experientia 19920715

Title: Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.

Journal: General pharmacology 19920301

Title: Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96(3):259-68.

Title: Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5(3-4):193-8.

Title: Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21(2):143-4.

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Tags:1758-80-1 Molecular Formula|1758-80-1 MDL|1758-80-1 SMILES|1758-80-1 Butanoic acid, 2,4-diamino-, (2S)-