Title: Axonal protection achieved by blockade of sodium/calcium exchange in a new model of ischemia in vivo.
Journal: Neuropharmacology 20120901
Title: TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts.
Journal: Cell calcium 20120801
Title: Reverse-mode NCX current in mouse airway smooth muscle: Na(+) and voltage dependence, contributions to Ca(2+) influx and contraction, and altered expression in a model of allergen-induced hyperresponsiveness.
Journal: Acta physiologica (Oxford, England) 20120601
Title: Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ET(B) receptor-mediated pathway in beating rabbit atria.
Journal: Life sciences 20120522
Title: Effects of low glucose on carotid body chemoreceptor cell activity studied in cultures of intact organs and in dissociated cells.
Journal: American journal of physiology. Cell physiology 20120415
Title: High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943.
Journal: British journal of pharmacology 20120401
Title: Vasopressin and oxytocin excite MCH neurons, but not other lateral hypothalamic GABA neurons.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120401
Title: Calcium dependence of damage to mouse motor nerve terminals following oxygen/glucose deprivation.
Journal: Experimental neurology 20120301
Title: Molecular and functional characterization of the human platelet Na(+) /Ca(2+) exchangers.
Journal: British journal of pharmacology 20120201
Title: PPADS, a P2X receptor antagonist, as a novel inhibitor of the reverse mode of the Na⁺/Ca²⁺ exchanger in guinea pig airway smooth muscle.
Journal: European journal of pharmacology 20120115
Title: Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons.
Journal: PloS one 20120101
Title: Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.
Journal: Life sciences 20110704
Title: The protective effect of mitochondrial ATP-sensitive K+ channel opener, nicorandil, combined with Na+/Ca2+ exchange blocker KB-R7943 on myocardial ischemia-reperfusion injury in rat.
Journal: Cell biochemistry and biophysics 20110701
Title: Mitochondrial and cytosolic calcium in rat hearts under high-K(+) cardioplegia and pyruvate: mechano-energetic performance.
Journal: Canadian journal of physiology and pharmacology 20110701
Title: Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells.
Journal: American journal of physiology. Cell physiology 20110601
Title: Mechanistic distinction between activation and inhibition of (Na(+)+K(+))-ATPase-mediated Ca2+ influx in cardiomyocytes.
Journal: Biochemical and biophysical research communications 20110311
Title: A role for orexin in central vestibular motor control.
Journal: Neuron 20110224
Title: KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I.
Journal: British journal of pharmacology 20110101
Title: Inhibition of spontaneous activity of rabbit atrioventricular node cells by KB-R7943 and inhibitors of sarcoplasmic reticulum Ca(2+) ATPase.
Journal: Cell calcium 20110101
Title: Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells.
Journal: Journal of pharmacological sciences 20110101
Title: Sodium-calcium exchange in intracellular calcium handling of human airway smooth muscle.
Journal: PloS one 20110101
Title: Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats.
Journal: Brain research 20101217
Title: Ca2+ paradox injury mediated through TRPC channels in mouse ventricular myocytes.
Journal: British journal of pharmacology 20101201
Title: Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells.
Journal: American journal of physiology. Cell physiology 20101201
Title: KB-R7943 inhibits Na+-dependent Mg2+ efflux in rat ventricular myocytes.
Journal: The journal of physiological sciences : JPS 20101101
Title: Kisspeptin directly excites anorexigenic proopiomelanocortin neurons but inhibits orexigenic neuropeptide Y cells by an indirect synaptic mechanism.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
Title: Cardiac basal metabolism: energetic cost of calcium withdrawal in the adult rat heart.
Journal: Acta physiologica (Oxford, England) 20100701
Title: Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.
Journal: Diabetes 20100701
Title: Effects of sarcolemmal Ca(2+) entry, ryanodine function, and kinase inhibitors on a rabbit model of heart failure.
Journal: International heart journal 20100701
Title: Electrophysiological characterization of store-operated and agonist-induced Ca2+ entry pathways in endothelial cells.
Journal: Pflugers Archiv : European journal of physiology 20100601
Title: The 1.3 isoform of Na+-Ca 2+ exchanger expressed in guinea pig tracheal smooth muscle is less sensitive to KB-R7943.
Journal: Journal of physiology and biochemistry 20100601
Title: Postconditioning in mouse hearts is inhibited by blocking the reverse mode of the sodium-calcium exchanger.
Journal: Interactive cardiovascular and thoracic surgery 20100501
Title: Inhibition of sodium-calcium exchange by KB-R7943: Dodecylamine and sphingosine in transfected Chinese hamster ovary cells.
Journal: Cell calcium 20100501
Title: Na+-Ca2+ exchanger contributes to Ca2+ extrusion in ATP-stimulated endothelium of intact rat aorta.
Journal: Biochemical and biophysical research communications 20100423
Title: Calcium transport and homeostasis in gill cells of a freshwater crab Dilocarcinus pagei.
Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301
Title: KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion.
Journal: Biochemical and biophysical research communications 20100219
Title: Neuroprotective effect of KB-R7943 against glutamate excitotoxicity is related to mild mitochondrial depolarization.
Journal: Neurochemical research 20100201
Title: Different mechanisms of Ca2+ regulation that influence synaptic transmission: comparison between crayfish and Drosophila neuromuscular junctions.
Journal: Synapse (New York, N.Y.) 20091201
Title: Involvement of Na+/Ca2+ exchanger in migration and contraction of rat cultured tendon fibroblasts.
Journal: The Journal of physiology 20091115
Title: Reactive oxygen species directly modify sodium-calcium exchanger activity in a splice variant-dependent manner.
Journal: Journal of molecular and cellular cardiology 20091101
Title: Digoxin and ouabain induce P-glycoprotein by activating calmodulin kinase II and hypoxia-inducible factor-1alpha in human colon cancer cells.
Journal: Toxicology and applied pharmacology 20091101
Title: Pharmacological modifications of the stretch-induced effects on ventricular fibrillation in perfused rabbit hearts.
Journal: American journal of physiology. Heart and circulatory physiology 20091101
Title: Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1.
Journal: The Journal of biological chemistry 20091002
Title: Hypoxia-induced cytosolic calcium decrease is mediated primarily by the forward mode of Na(+)/Ca(2+) exchanger in smooth muscle cells of fetal ductus arteriosus.
Journal: Pediatric cardiology 20091001
Title: The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels.
Journal: Molecular pharmacology 20090901
Title: Dofetilide enhances the contractility of rat ventricular myocytes via augmentation of Na+-Ca 2+ exchange.
Journal: Cardiovascular drugs and therapy 20090601
Title: Contribution of Na+/Ca2+ exchange current to the formation of delayed afterdepolarizations in intact rat ventricular muscle.
Journal: Journal of cardiovascular pharmacology 20090601
Title: A key role for dense granule secretion in potentiation of the Ca2+ signal arising from store-operated calcium entry in human platelets.
Journal: Cell calcium 20090501
Title: The Na+/Ca2+ exchanger inhibitor, KB-R7943, blocks a nonselective cation channel implicated in chemosensory transduction.
Journal: Journal of neurophysiology 20090301
Title: Cardiac myocyte excitation by ultrashort high-field pulses.
Journal: Biophysical journal 20090218
Title: Mitochondrial regulation of sarcoplasmic reticulum Ca2+ content in vascular smooth muscle cells.
Journal: Circulation research 20090102
Title: Potential therapeutic effects of Na+/Ca2+ exchanger inhibition in cardiac diseases.
Journal: Current medicinal chemistry 20090101
Title: New insights in the contribution of voltage-gated Na(v) channels to rat aorta contraction.
Journal: PloS one 20090101
Title: Role of TRP channels and NCX in mediating hypoxia-induced [Ca(2+)](i) elevation in PC12 cells.
Journal: Respiratory physiology & neurobiology 20081231
Title: Intracellular Na(+) modulates large conductance Ca(2+)-activated K (+) currents in human umbilical vein endothelial cells.
Journal: Pflugers Archiv : European journal of physiology 20081001
Title: High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+).
Journal: European journal of applied physiology 20081001
Title: Na+/Ca2+ exchanger inhibitor ameliorates impaired endothelium-dependent Na+ relaxation induced by high glucose in rat aorta.
Journal: Clinical and experimental pharmacology & physiology 20081001
Title: [Effects of Astragalus membranaceus on atrial dynamics and ANP secretion].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001
Title: Endothelial nitric oxide attenuates Na+/Ca2+ exchanger-mediated vasoconstriction in rat aorta.
Journal: British journal of pharmacology 20080701
Title: Attenuation of maitotoxin-induced cytotoxicity in rat aortic smooth muscle cells by inhibitors of Na+/Ca2+ exchange, and calpain activation.
Journal: Toxicon : official journal of the International Society on Toxinology 20080615
Title: The ins and outs of calcium in heart failure.
Journal: Circulation research 20080606
Title: An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20080501
Title: Cerebral microvascular nNOS responds to lowered oxygen tension through a bumetanide-sensitive cotransporter and sodium-calcium exchanger.
Journal: American journal of physiology. Heart and circulatory physiology 20080501
Title: Ranolazine inhibits an oxidative stress-induced increase in myocyte sodium and calcium loading during simulated-demand ischemia.
Journal: Journal of cardiovascular pharmacology 20080501
Title: The Na(+)/Ca(2+) exchanger inhibitor KB-R7943 activates large-conductance Ca(2+)-activated K(+) channels in endothelial and vascular smooth muscle cells.
Journal: European journal of pharmacology 20080317
Title: [Role of sodium-calcium exchanger in the myocardial protection against ischemia-reperfusion injury].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080301
Title: Differential effects of the sodium calcium exchange inhibitor, KB-R7943, on ischemia and reperfusion injury in isolated guinea pig ventricular myocytes.
Journal: European journal of pharmacology 20080202
Title: Angiotensin II-stimulated Ca2+ entry mechanisms in afferent arterioles: role of transient receptor potential canonical channels and reverse Na+/Ca2+ exchange.
Journal: American journal of physiology. Renal physiology 20080101
Title: Cell culture alters Ca2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells.
Journal: American journal of physiology. Cell physiology 20080101
Title: A key role for reverse Na+/Ca2+ exchange influenced by the actin cytoskeleton in store-operated Ca2+ entry in human platelets: evidence against the de novo conformational coupling hypothesis.
Journal: Cell calcium 20071201
Title: SR Ca2+ refilling upon depletion and SR Ca2+ uptake rates during development in rabbit ventricular myocytes.
Journal: American journal of physiology. Cell physiology 20071201
Title: Characterization of SN-6, a novel Na+/Ca2+ exchange inhibitor in guinea pig cardiac ventricular myocytes.
Journal: European journal of pharmacology 20071114
Title: The participation of the Na+-Ca2+ exchanger in primary cardiac myofibroblast migration, contraction, and proliferation.
Journal: Journal of cellular physiology 20071101
Title: Carbachol exhibited positive inotropic effect on rat ventricular myocytes via M₂ muscarinic receptors.
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20071025
Title: Diastolic Ca2+ overload caused by Na+/Ca2+ exchanger during the first minutes of reperfusion results in continued myocardial stunning.
Journal: European journal of pharmacology 20071015
Title: The Na+/Ca2+ exchange inhibitor KB-R7943 potently blocks TRPC channels.
Journal: Biochemical and biophysical research communications 20070914
Title: Changes in calcium dynamics following the reversal of the sodium-calcium exchanger have a key role in AMPA receptor-mediated neurodegeneration via calpain activation in hippocampal neurons.
Journal: Cell death and differentiation 20070901
Title: Characterization of noradrenaline-induced increases in intracellular Ca2+ levels in Chinese hamster ovary cells stably expressing human alpha1A-adrenoceptor.
Journal: Journal of pharmacological sciences 20070901
Title: Store-refilling involves both L-type calcium channels and reverse-mode sodium-calcium exchange in airway smooth muscle.
Journal: The European respiratory journal 20070801
Title: Preservation of mitochondrial function may contribute to cardioprotective effects of Na+/Ca2+ exchanger inhibitors in ischaemic/reperfused rat hearts.
Journal: British journal of pharmacology 20070801
Title: Functional coupling between the Na+/Ca2+ exchanger and nonselective cation channels during histamine stimulation in guinea pig tracheal smooth muscle.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070701
Title: The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter.
Journal: British journal of pharmacology 20070701
Title: Na+/Ca2+ exchange and regulation of cytoplasmic concentration of calcium in rat cerebellar neurons treated with glutamate.
Journal: Biochemistry. Biokhimiia 20070701
Title: Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle.
Journal: American journal of respiratory cell and molecular biology 20070501
Title: Role of reverse mode Na+/Ca2+ exchanger in the cardioprotection of metabolic inhibition preconditioning in rat ventricular myocytes.
Journal: European journal of pharmacology 20070430
Title: Involvement of Na+-Ca2+ exchanger on metabotropic glutamate receptor 1-mediated [Ca2+]i transients in rat cerebellar Purkinje neurons.
Journal: Neuroscience 20070425
Title: [Na+/Ca2+ exchanger (NCX1) and cardiovascular disease].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070401
Title: CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury.
Journal: Cardiovascular research 20070301
Title: The role of Na+/Ca2+ exchanger in endothelin-1-aggravated hypoxia/reoxygenation-induced injury in renal epithelial cells.
Journal: Annals of the New York Academy of Sciences 20070301
Title: The reverse mode of the Na(+)/Ca(2+) exchanger provides a source of Ca(2+) for store refilling following agonist-induced Ca(2+) mobilization.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070201
Title: Propofol modulates Na+-Ca2+ exchange activity via activation of protein kinase C in diabetic cardiomyocytes.
Journal: Anesthesiology 20070201
Title: Calcium regulation in individual peripheral sensory nerve terminals of the rat.
Journal: The Journal of physiology 20070115
Title: Effects of purified endogenous inhibitor of the Na+/Ca2+ exchanger on ouabain-induced arrhythmias in the atria and ventricle strips of guinea pig.
Journal: European journal of pharmacology 20061228
Title: 5-Hydroxytryptamine contributes significantly to a reflex pathway by which the duodenal mucosa protects itself from gastric acid injury.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201
Title: The influence of sodium-calcium exchange inhibitors on rabbit lens ion balance and transparency.
Journal: Experimental eye research 20061101
Title: Single alpha-domain constructs of the Na+/Ca2+ exchanger, NCLX, oligomerize to form a functional exchanger.
Journal: Biochemistry 20061003
Title: Na+/Ca2+ exchanger modulates the flagellar wave pattern for the regulation of motility activation and chemotaxis in the ascidian spermatozoa.
Journal: Cell motility and the cytoskeleton 20061001
Title: Muscarine activates the sodium-calcium exchanger via M receptors in basal forebrain neurons.
Journal: The European journal of neuroscience 20061001
Title: Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus.
Journal: Circulation 20060926
Title: Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle.
Journal: American journal of physiology. Heart and circulatory physiology 20060901
Title: Loading rat heart myocytes with Mg2+ using low-[Na+] solutions.
Journal: The Journal of physiology 20060901
Title: Anesthetic preconditioning enhances Ca2+ handling and mechanical and metabolic function elicited by Na+-Ca2+ exchange inhibition in isolated hearts.
Journal: Anesthesiology 20060901
Title: Inhibition by SEA0400, a selective inhibitor of Na+/Ca2+ exchanger, of Na+ -dependent Ca2+ uptake and catecholamine release in bovine adrenal chromaffin cells.
Journal: Journal of pharmacological sciences 20060901
Title: Quantitative fluorescence measurement of cardiac Na+/Ca2+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells.
Journal: Journal of pharmacological sciences 20060801
Title: Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger.
Journal: Circulation 20060704
Title: Effects of a Na+/Ca2+ exchanger inhibitor on pulmonary vein electrical activity and ouabain-induced arrhythmogenicity.
Journal: Cardiovascular research 20060601
Title: High potassium concentrations protect inner and outer hair cells in the newborn rat culture from ischemia-induced damage.
Journal: Hearing research 20060501
Title: Fundamental importance of Na+-Ca2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node.
Journal: The Journal of physiology 20060315
Title: Effects of caffeine, verapamil, lithium, and KB-R7943 on mechanics and energetics of rat myocardial bigeminies.
Journal: American journal of physiology. Heart and circulatory physiology 20060201
Title: Sodium-dependent recovery of ionised magnesium concentration following magnesium load in rat heart myocytes.
Journal: Pflugers Archiv : European journal of physiology 20060201
Title: Role of the Na+/Ca2+ exchanger in calcium homeostasis and human sperm motility regulation.
Journal: Cell motility and the cytoskeleton 20060201
Title: Involvement of Na+/Ca2+ exchanger in catecholamine-induced increase in intracellular calcium in cardiomyocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20060101
Title: [Na+/Ca2+ exchanger(NCX1) and salt-sensitive hypertension].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060101
Title: Sodium calcium exchange as a target for antiarrhythmic therapy.
Journal: Handbook of experimental pharmacology 20060101
Title: Stretch-dependent modulation of [Na+]i, [Ca2+]i, and pHi in rabbit myocardium--a mechanism for the slow force response.
Journal: Cardiovascular research 20051201
Title: The inhibitory effect of ouabain on the response of slowly adapting pulmonary stretch receptors to hyperinflation in the rabbit.
Journal: Life sciences 20051119
Title: Na+-K+ pump activation inhibits endothelium-dependent relaxation by activating the forward mode of Na+/Ca2+ exchanger in mouse aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20051101
Title: Transport of extracellular l-arginine via cationic amino acid transporter is required during in vivo endothelial nitric oxide production.
Journal: American journal of physiology. Heart and circulatory physiology 20051001
Title: Involvement of Na+-Ca2+ exchanger in intracellular Ca2+ increase and neuronal injury induced by polychlorinated biphenyls in human neuroblastoma SH-SY5Y cells.
Journal: The Journal of pharmacology and experimental therapeutics 20051001
Title: Electrophysiological and molecular identification of voltage-gated sodium channels in murine vascular myocytes.
Journal: The Journal of physiology 20051001
Title: Probing the endogenous Ca2+ buffers at the presynaptic terminals of the crayfish neuromuscular junction.
Journal: Journal of neurophysiology 20050701
Title: Inhibition of the reverse mode of the Na+/Ca2+ exchange by KB-R7943 augments arrhythmogenicity in the canine heart during rapid heart rates.
Journal: Journal of electrocardiology 20050701
Title: Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050701
Title: Mechanism-based modeling of reduced inotropic responsiveness to digoxin in endotoxemic rat hearts.
Journal: European journal of pharmacology 20050502
Title: Therapeutic potential of novel Na+-Ca2+ exchange inhibitors in attenuating ischemia-reperfusion injury.
Journal: The Canadian journal of cardiology 20050501
Title: Na+/Ca2+ exchanger activity modulates connective tissue growth factor mRNA expression in transforming growth factor beta1- and Des-Arg10-kallidin-stimulated myofibroblasts.
Journal: The Journal of biological chemistry 20050415
Title: Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes.
Journal: American journal of physiology. Heart and circulatory physiology 20050401
Title: Role of phosphorylation of Thr(17) residue of phospholamban in mechanical recovery during hypercapnic acidosis.
Journal: Cardiovascular research 20050401
Title: Na(+)/Ca(2+) exchange regulates Ca(2+)-dependent duodenal mucosal ion transport and HCO(3)(-) secretion in mice.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050301
Title: Protection of ischemic rat spinal cord white matter: Dual action of KB-R7943 on Na+/Ca2+ exchange and L-type Ca2+ channels.
Journal: Neuropharmacology 20050301
Title: Sodium channels are required during in vivo sodium chloride hyperosmolarity to stimulate increase in intestinal endothelial nitric oxide production.
Journal: American journal of physiology. Heart and circulatory physiology 20050101
Title: Fowl (Gallus domesticus) sperm motility depends upon mitochondrial calcium cycling driven by extracellular sodium.
Journal: Biology of reproduction 20050101
Title: Effects of Na+-Ca2+ exchanger activity on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolone-propionate-induced Ca2+ influx in cerebellar Purkinje neurons.
Journal: Neuroscience 20050101
Title: Cardioprotective effects of KB-R7943, a novel inhibitor of Na+/Ca2+ exchanger, on stunned myocardium in anesthetized dogs.
Journal: Journal of anesthesia 20050101
Title: The role of Ca2+ transport across the plasma membrane for cell migration.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101
Title: Functional differences of Na+/Ca2+ exchanger expression in Ca2+ transport system of smooth muscle of guinea pig stomach.
Journal: Canadian journal of physiology and pharmacology 20050101
Title: Cross-talk between native plasmalemmal Na+/Ca2+ exchanger and inositol 1,4,5-trisphosphate-sensitive ca2+ internal store in Xenopus oocytes.
Journal: The Journal of biological chemistry 20041210
Title: Endothelin-1 aggravates hypoxia/reoxygenation-induced injury in renal epithelial cells through the activation of a Na+/Ca2+ exchanger.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Systems analysis of digoxin kinetics and inotropic response in the rat heart: effects of calcium and KB-R7943.
Journal: American journal of physiology. Heart and circulatory physiology 20041001
Title: Presynaptic alpha2-receptors regulate reverse Na+/Ca2+-exchange and transmitter release in Na+-loaded peripheral sympathetic nerves.
Journal: Neurochemistry international 20041001
Title: Participation of Na/Ca-exchanger and sarcoplasmic reticulum in the high [K]-protection against ischaemia-reperfusion dysfunction in rat hearts.
Journal: Acta physiologica Scandinavica 20041001
Title: High activity of K+-dependent plasmalemmal Na+/Ca2+ exchangers in hippocampal CA1 neurons.
Journal: Neuroreport 20040915
Title: Sodium-calcium exchanger contributes to membrane hyperpolarization of intact endothelial cells from rat aorta during acetylcholine stimulation.
Journal: British journal of pharmacology 20040901
Title: A sea urchin egg jelly peptide induces a cGMP-mediated decrease in sperm intracellular Ca(2+) before its increase.
Journal: Developmental biology 20040815
Title: Is modulation of sodium-calcium exchange a therapeutic option in heart failure?
Journal: Circulation research 20040806
Title: Effects of sodium-calcium exchange inhibitors, KB-R7943 and SEA0400, on aconitine-induced arrhythmias in guinea pigs in vivo, in vitro, and in computer simulation studies.
Journal: The Journal of pharmacology and experimental therapeutics 20040701
Title: Differential contribution of plasmalemmal Na/Ca exchange isoforms to sodium-dependent calcium influx and NMDA excitotoxicity in depolarized neurons.
Journal: Journal of neurochemistry 20040701
Title: Na+/Ca2+ exchange inhibitors: potential drugs to mitigate the severity of ischemic injury.
Journal: Molecular pharmacology 20040701
Title: Counteracting effects of NADPH oxidase and the Na+/Ca2+ exchanger on membrane repolarisation and store-operated uptake of Ca2+ by chemoattractant-activated human neutrophils.
Journal: Biochemical pharmacology 20040615
Title: The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease.
Journal: Expert opinion on investigational drugs 20040601
Title: Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.
Journal: The Journal of biological chemistry 20040402
Title: Calcium dynamics and vasomotion in rat mesenteric arteries.
Journal: Journal of cardiovascular pharmacology 20040401
Title: Development and application of Na+/Ca2+ exchange inhibitors.
Journal: Molecular and cellular biochemistry 20040401
Title: Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400.
Journal: The Journal of biological chemistry 20040227
Title: KB-R7943 reveals possible involvement of Na(+)-Ca2+ exchanger in elevation of intracellular Ca2+ in rat carotid arterial myocytes.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20040201
Title: [Effect of inhibitors of sodium-calcium exchangers on acetylcholine-induced hyperpolarization of endothelial cells in rat aorta].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101
Title: Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.
Journal: Neuroscience 20040101
Title: Aspartate release from rat hippocampal synaptosomes.
Journal: Neuroscience 20040101
Title: Physiological role of the sodium-calcium exchanger in tracheal smooth muscle of guinea pig.
Journal: Journal of muscle research and cell motility 20040101
Title: A low dose of angiotensin II increases inotropism through activation of reverse Na(+)/Ca(2+) exchange by endothelin release.
Journal: Cardiovascular research 20031201
Title: Ca2+-dependent modulation of intracellular Mg2+ concentration with amiloride and KB-R7943 in pig carotid artery.
Journal: The Journal of biological chemistry 20031128
Title: Influence of Na+-independent Cl--HCO3- exchange on the slow force response to myocardial stretch.
Journal: Circulation research 20031128
Title: Influence of lidocaine on ouabain-induced inotropic response in rat atria.
Journal: Biochemical pharmacology 20031101
Title: A novel and selective Na+/Ca2+ exchange inhibitor, SEA0400, improves ischemia/reperfusion-induced renal injury.
Journal: European journal of pharmacology 20031008
Title: Resting membrane potential regulates Na(+)-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes.
Journal: The Journal of physiology 20030801
Title: Na(+)-Ca2+ exchange function underlying contraction frequency inotropy in the cat myocardium.
Journal: The Journal of physiology 20030801
Title: Does enhanced expression of the Na+-Ca2+ exchanger increase myocardial vulnerability to ischemia/reperfusion injury in rabbit hearts?
Journal: Molecular and cellular biochemistry 20030601
Title: Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.
Journal: European journal of pharmacology 20030319
Title: Differing cardioprotective efficacy of the Na+/Ca2+ exchanger inhibitors SEA0400 and KB-R7943.
Journal: American journal of physiology. Heart and circulatory physiology 20030301
Title: Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
Journal: European journal of pharmacology 20030214
Title: Attenuation of ischemia/reperfusion-induced renal injury in mice deficient in Na+/Ca2+ exchanger.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia-reperfusion injuries.
Journal: European journal of pharmacology 20030101
Title: Importance of Ca2+ influx by Na+/Ca2+ exchange under normal and sodium-loaded conditions in mammalian ventricles.
Journal: Molecular and cellular biochemistry 20030101
Title: Pharmacology of KB-R7943: a Na+-Ca2+ exchange inhibitor.
Journal: Cardiovascular drug reviews 20030101
Title: Quantitative analysis of hyperosmotic and hypothermic blood-brain barrier opening.
Journal: Acta neurochirurgica. Supplement 20030101
Title: In depolarized and glucose-deprived neurons, Na+ influx reverses plasmalemmal K+-dependent and K+-independent Na+/Ca2+ exchangers and contributes to NMDA excitotoxicity.
Journal: Journal of neurochemistry 20021201
Title: Negative and positive inotropic effects of propofol via L-type calcium channels and the sodium-calcium exchanger in rat cardiac trabeculae.
Journal: Anesthesiology 20021101
Title: [Functional analysis of Na+/Ca2+ exchanger using novel drugs and genetically engineered mice].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101
Title: KB-R7943, a Na+/Ca2+ exchange inhibitor, does not suppress ischemia/reperfusion arrhythmias nor digitalis arrhythmias in dogs.
Journal: Japanese journal of pharmacology 20021101
Title: Electrophysiological studies of the cloned rat cardiac NCX1.1 in transfected HEK cells: a focus on the stoichiometry.
Journal: Annals of the New York Academy of Sciences 20021101
Title: Pharmacology of Na+/Ca2+ exchanger.
Journal: Annals of the New York Academy of Sciences 20021101
Title: Effect of KB-R7943 on oscillatory Na+/Ca2+ exchange current in guinea pig ventricular myocytes.
Journal: Annals of the New York Academy of Sciences 20021101
Title: Inhibition of the Drosophila Na+/Ca2) exchanger, CALX1.1, by KB-R7943.
Journal: Annals of the New York Academy of Sciences 20021101
Title: Modulation of exocytosis by the Na(+)/Ca(2+) exchanger of chromaffin cells.
Journal: Annals of the New York Academy of Sciences 20021001
Title: Kb-R7943 prevents acute, atrial fibrillation-induced shortening of atrial refractoriness in anesthetized dogs.
Journal: Circulation 20020910
Title: Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility.
Journal: Circulation research 20020906
Title: Effect of inhibition of Na(+)/Ca(2+) exchanger at the time of myocardial reperfusion on hypercontracture and cell death.
Journal: Cardiovascular research 20020901
Title: Lithium and KB-R7943 effects on mechanics and energetics of rat heart muscle.
Journal: Acta physiologica Scandinavica 20020901
Title: Developmental changes of Ca(2+) handling in mouse ventricular cells from early embryo to adulthood.
Journal: Life sciences 20020802
Title: Involvement of Na(+)/Ca(2+) exchanger in endothelial NO production and endothelium-dependent relaxation.
Journal: American journal of physiology. Heart and circulatory physiology 20020801
Title: Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors.
Journal: Circulation research 20020726
Title: Amiloride and KB-R7943 in outward Na+ /Ca2+ exchange current in guinea pig ventricular myocytes.
Journal: Journal of cardiovascular pharmacology 20020701
Title: Blockade of the Na+-Ca2+ exchanger is more efficient than blockade of the Na+-H+ exchanger for protection of the myocardium from lethal reperfusion injury.
Journal: Cardiovascular drugs and therapy 20020701
Title: Inhibition by KB-r7943 of the reverse mode of the Na+/Ca2+ exchanger reduces Ca2+ overload in ischemic-reperfused rat hearts.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20020401
Title: Instrumental role of Na+ in NMDA excitotoxicity in glucose-deprived and depolarized cerebellar granule cells.
Journal: Journal of neurochemistry 20020401
Title: Autocrine stimulation of cardiac Na(+)-Ca(2+) exchanger currents by endogenous endothelin released by angiotensin II.
Journal: Circulation research 20020308
Title: Synergistic effect of cold mannitol and Na(+)/Ca(2+) exchange blocker on blood-brain barrier opening.
Journal: Biochemical and biophysical research communications 20020301
Title: Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents.
Journal: British journal of pharmacology 20020301
Title: Time course and mechanisms of phosphorylation of phospholamban residues in ischemia-reperfused rat hearts. Dissociation of phospholamban phosphorylation pathways.
Journal: Journal of molecular and cellular cardiology 20020101
Title: Role of Na(+)-Ca(2+) exchanger after traumatic or hypoxic/ischemic injury to spinal cord white matter.
Journal: The spine journal : official journal of the North American Spine Society 20020101
Title: Roles for mitochondrial and reverse mode Na+/Ca2+ exchange and the plasmalemma Ca2+ ATPase in post-tetanic potentiation at crayfish neuromuscular junctions.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215
Title: Reperfusion arrhythmias: new insights into the role of the Na(+)/Ca(2+) exchanger.
Journal: Journal of molecular and cellular cardiology 20011201
Title: Very low dose of the Na(+)/Ca(2+) exchange inhibitor, KB-R7943, protects ischemic reperfused aged Fischer 344 rat hearts: considerable strain difference in the sensitivity to KB-R7943.
Journal: Cardiovascular research 20011201
Title: KB-R7943. Kanebo.
Journal: Current opinion in investigational drugs (London, England : 2000) 20011201
Title: Gender influences [Ca(2+)](i) during metabolic inhibition in myocytes overexpressing the Na(+)-Ca(2+) exchanger.
Journal: Circulation 20011023
Title: Inhibition of Na(+)/Ca(2+) exchange by KB-R7943, a novel selective antagonist, attenuates phosphoethanolamine and free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury.
Journal: Brain research 20011019
Title: On the source of Ca(2+) activating the tonic component of contraction of myocytes of guinea pig heart.
Journal: Cardiovascular research 20011001
Title: Reperfusion-induced Ins(1,4,5)P(3) generation and arrhythmogenesis require activation of the Na(+)/Ca(2+) exchanger.
Journal: Journal of molecular and cellular cardiology 20011001
Title: Inhibition of Na+/Ca2+ exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences.
Journal: American journal of physiology. Heart and circulatory physiology 20010901
Title: Cardiac sodium-calcium exchanger: a double-edged sword.
Journal: Cardiovascular research 20010801
Title: Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury.
Journal: Cardiovascular research 20010801
Title: Inhibition of Na+/Ca2+ exchange with KB-R7943 or bepridil diminished mineral deposition by osteoblasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010801
Title: Differential roles of the sodium-calcium exchanger in renin secretion and renal vascular resistance.
Journal: Pflugers Archiv : European journal of physiology 20010801
Title: SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.
Journal: The Journal of pharmacology and experimental therapeutics 20010701
Title: Sodium-calcium exchanger (NCX-1) and calcium modulation: NCX protein expression patterns and regulation of early heart development.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20010701
Title: The effects of the Na(+)/Ca(++) exchange blocker on osmotic blood-brain barrier disruption.
Journal: Brain research 20010511
Title: Inhibition of aggregation of rabbit and human platelets induced by adrenaline and 5-hydroxytryptamine by KB-R7943, a Na(+)/Ca(2+) exchange inhibitor.
Journal: British journal of pharmacology 20010401
Title: Structural domains influencing sensitivity to isothiourea derivative inhibitor KB-R7943 in cardiac Nna(+)/Ca(2+) exchanger.
Journal: Molecular pharmacology 20010301
Title: The sodium pump modulates the influence of I(Na) on [Ca2+]i transients in mouse ventricular myocytes.
Journal: Biophysical journal 20010301
Title: KB-R7943, a selective Na+/Ca2+ exchange inhibitor, protects against ischemic acute renal failure in mice by inhibiting renal endothelin-1 overproduction.
Journal: Journal of cardiovascular pharmacology 20010301
Title: Pre- or post-ischemic treatment with a novel Na+/Ca2+ exchange inhibitor, KB-R7943, shows renal protective effects in rats with ischemic acute renal failure.
Journal: The Journal of pharmacology and experimental therapeutics 20010201
Title: Functional role of sodium-calcium exchange in the regulation of renal vascular resistance.
Journal: American journal of physiology. Renal physiology 20010101
Title: Protein kinase C suppresses spontaneous, transient, outwards K+ currents through modulation of the Na/Ca exchanger in guinea-pig gastric myocytes.
Journal: Pflugers Archiv : European journal of physiology 20010101
Title: [The Na+/Ca2+ exchanger as responsible for myocardial stunning].
Journal: Medicina 20010101
Title: Na(+)-K(+)-ATPase inhibition and depolarization induce glutamate release via reverse Na(+)-dependent transport in spinal cord white matter.
Journal: Neuroscience 20010101
Title: [Effect of KB-R7943 on Na(+)-Ca2+ exchange current in guinea pig ventricular myocytes].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010101
Title: ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells.
Journal: American journal of physiology. Cell physiology 20000301
Title: Brustovetsky T, et al. KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I. Br J Pharmacol. 2011 Jan;162(1):255-70.
Title: Barrientos G, et al. The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate(KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Mol Pharmacol. 2009 Sep;76(3):560-8.
Title: Cheng H, et al. High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943. Br J Pharmacol. 2012 Apr;165(7):2260-73.
Title: Long Z, et al. The reverse-mode NCX1 activity inhibitor KB-R7943 promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux. Oncotarget. 2016;7(27):42059-70.
