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182485-36-5,MFCD01074806
Catalog No.:AA0023U0

182485-36-5 | Tpmpa

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10mg
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50mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0023U0
Chemical Name:
Tpmpa
CAS Number:
182485-36-5
Molecular Formula:
C6H12NO2P
Molecular Weight:
161.1387
MDL Number:
MFCD01074806
SMILES:
CP(=O)(C1=CCNCC1)O
Properties
Computed Properties
 
Complexity:
200  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-3.5  

Literature

Title: Paired-pulse plasticity in the strength and latency of light-evoked lateral inhibition to retinal bipolar cell terminals.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120822

Title: Dopamine and serotonin modulate human GABAρ1 receptors expressed in Xenopus laevis oocytes.

Journal: ACS chemical neuroscience 20120215

Title: Nonlinear interactions between excitatory and inhibitory retinal synapses control visual output.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019

Title: Potentiating action of propofol at GABAA receptors of retinal bipolar cells.

Journal: Investigative ophthalmology & visual science 20110401

Title: GABA(A) ρ receptor mechanisms in the rat amygdala and its role in the modulation of fear and anxiety.

Journal: Psychopharmacology 20101201

Title: Postnatal switch from synaptic to extrasynaptic transmission between interneurons and NG2 cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100519

Title: Selective induction of astrocytic gliosis generates deficits in neuronal inhibition.

Journal: Nature neuroscience 20100501

Title: GABAC receptors are functionally expressed in the intermediate zone and regulate radial migration in the embryonic mouse neocortex.

Journal: Neuroscience 20100428

Title: GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113

Title: Antagonists of ionotropic gamma-aminobutyric acid receptors impair the NiCl2-mediated stimulation of the electroretinogram b-wave amplitude from the isolated superfused vertebrate retina.

Journal: Acta ophthalmologica 20091101

Title: Neuroligin-2 accelerates GABAergic synapse maturation in cerebellar granule cells.

Journal: Molecular and cellular neurosciences 20090901

Title: The GABAergic system in the retina of neonate and adult Octodon degus, studied by immunohistochemistry and electroretinography.

Journal: The Journal of comparative neurology 20090610

Title: The GABA(A) receptor-mediated inhibitory pathway increases the correlated activities in retinal ganglion cells.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20090425

Title: Molecular modeling of ligand-receptor interactions in GABA C receptor.

Journal: Journal of molecular graphics & modelling 20090401

Title: Participation of GABA-ergic system in epileptogenic activity induced by teicoplanin in mice.

Journal: Epilepsy research 20090401

Title: The involvement of GABA-C receptors in paired-pulse depression of inhibitory postsynaptic currents in rat hippocampal CA1 pyramidal neurons.

Journal: Experimental neurology 20090301

Title: Novel gamma-aminobutyric acid rho1 receptor antagonists; synthesis, pharmacological activity and structure-activity relationships.

Journal: Journal of medicinal chemistry 20080710

Title: Development of presynaptic inhibition onto retinal bipolar cell axon terminals is subclass-specific.

Journal: Journal of neurophysiology 20080701

Title: GABAC-receptor stimulation activates cAMP-dependent protein kinase via A-kinase anchoring protein 220.

Journal: Journal of pharmacological sciences 20080401

Title: Relative impact of residues at the intracellular and extracellular ends of the human GABAC rho1 receptor M2 domain on picrotoxinin activity.

Journal: European journal of pharmacology 20080202

Title: Inhibitory feedback shapes bipolar cell responses in the rabbit retina.

Journal: Journal of neurophysiology 20071201

Title: 5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists.

Journal: Journal of medicinal chemistry 20070823

Title: Phosphonic acid analogs of GABA through reductive dealkylation of phosphonic diesters with lithium trialkylborohydrides.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Functional evidence for GABA as modulator of the contractility of the longitudinal muscle in mouse duodenum: role of GABA(A) and GABA(C) receptors.

Journal: Neuropharmacology 20070601

Title: Involvement of chloride channel coupled GABA(C) receptors in the peripheral antinociceptive effect induced by GABA(C) receptor agonist cis-4-aminocrotonic acid.

Journal: Life sciences 20070313

Title: Baclofen, an agonist at peripheral GABAB receptors, induces antinociception via activation of TEA-sensitive potassium channels.

Journal: British journal of pharmacology 20061101

Title: The synaptic mechanism of direction selectivity in distal processes of starburst amacrine cells.

Journal: Neuron 20060921

Title: Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons.

Journal: Nature neuroscience 20060501

Title: Characterization of the glycinergic input to bipolar cells of the mouse retina.

Journal: The European journal of neuroscience 20060101

Title: Evidence for a functional role of GABA receptors in the rat mature hippocampus.

Journal: The European journal of neuroscience 20060101

Title: Analysis of macroscopic ionic currents mediated by GABArho1 receptors during lanthanide modulation predicts novel states controlling channel gating.

Journal: British journal of pharmacology 20051201

Title: Melatonin decreases calcium levels in retinotectal axons of Xenopus laevis by indirect activation of group III metabotropic glutamate receptors.

Journal: Brain research 20050816

Title: Synchronized retinal oscillations encode essential information for escape behavior in frogs.

Journal: Nature neuroscience 20050801

Title: Developmental changes of GABA synaptic transient in cerebellar granule cells.

Journal: Molecular pharmacology 20050401

Title: Pharmacology of GABAC receptors: responses to agonists and antagonists distinguish A- and B-subtypes of homomeric rho receptors expressed in Xenopus oocytes.

Journal: Neuroscience letters 20050307

Title: Opposing roles for GABAA and GABAC receptors in short-term memory formation in young chicks.

Journal: Neuroscience 20050101

Title: Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.

Journal: Neuron 20041028

Title: The spinal GABAergic system is a strong modulator of burst frequency in the lamprey locomotor network.

Journal: Journal of neurophysiology 20041001

Title: GABAC receptor agonist suppressed ammonia-induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated BAD level.

Journal: Journal of neurochemistry 20031101

Title: Timing of quantal release from the retinal bipolar terminal is regulated by a feedback circuit.

Journal: Neuron 20030410

Title: Temporal modulation of scotopic visual signals by A17 amacrine cells in mammalian retina in vivo.

Journal: Journal of neurophysiology 20030401

Title: Modulation of the components of the rat dark-adapted electroretinogram by the three subtypes of GABA receptors.

Journal: Visual neuroscience 20030101

Title: GABA(A) and GABA(C) receptor antagonists increase retinal cyclic GMP levels through nitric oxide synthase.

Journal: Visual neuroscience 20030101

Title: Gamma-aminobutyric acid-induced calcium signalling in rat superior collicular neurones.

Journal: Neuroscience letters 20021213

Title: Medicinal chemistry and molecular pharmacology of GABA(C) receptors.

Journal: Current topics in medicinal chemistry 20020801

Title: Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists.

Journal: Biophysical journal 20011101

Title: Modulation of excitatory synaptic transmission by GABA(C) receptor-mediated feedback in the mouse inner retina.

Journal: Journal of neurophysiology 20011101

Title: Pathway-specific targeting of GABA(A) receptor subtypes to somatic and dendritic synapses in the central amygdala.

Journal: Journal of neurophysiology 20010801

Title: Study of a GABAC receptor antagonist on sleep-waking behavior in rats.

Journal: Psychopharmacology 20010401

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