Home Amines 1779-81-3
1779-81-3,MFCD00005313
Catalog No.:AA0025IZ

1779-81-3 | 2-Amino-2-thiazoline

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1g
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5g
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25g
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100g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0025IZ
Chemical Name:
2-Amino-2-thiazoline
CAS Number:
1779-81-3
Molecular Formula:
C3H6N2S
Molecular Weight:
102.1581
MDL Number:
MFCD00005313
SMILES:
NC1=NCCS1
Properties
Computed Properties
 
Complexity:
78.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
-0.2  

Downstream Synthesis Route

[1]Chang,Lei;Duy,DoLe;Mébarek,Saida;Popowycz,Florence;Pellet-Rostaing,Stéphane;Lemaire,Marc;Buchet,René[BioorganicandMedicinalChemistryLetters,2011,vol.21,#8,p.2297-2301]

[2]Raeymaekers,A.H.M.etal.[JournalofMedicinalChemistry,1966,vol.9,p.545-551]

[1]JournalofMedicinalChemistry,1966,vol.9,p.545-551

[1]Arzneimittel-Forschung/DrugResearch,1974,vol.24,p.1785-1786

[1]JournalofMedicinalChemistry,1966,vol.9,p.545-551

[1]JournalofMedicinalChemistry,1977,vol.20,p.563-566

Literature

Title: Design and synthesis of 2-iminothiazolidin-4-one moiety-containing compounds as potent antiproliferative agents.

Journal: Archiv der Pharmazie 20120501

Title: Synthesis of novel isatin-thiazoline and isatin-benzimidazole conjugates as anti-breast cancer agents.

Journal: Archives of pharmacal research 20111001

Title: New synthetic thrombin inhibitors: molecular design and experimental verification.

Journal: PloS one 20110101

Title: Copper and its complexes in medicine: a biochemical approach.

Journal: Molecular biology international 20110101

Title: A selective and convenient method for the synthesis of 2-phenylaminothiazolines.

Journal: Organic letters 20101203

Title: Exploration of novel 2-alkylimino-1,3-thiazolines: T-type calcium channel inhibitory activity.

Journal: Journal of combinatorial chemistry 20100712

Title: Development of amino-oxazoline and amino-thiazoline organic catalysts for the ring-opening polymerisation of lactide.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100525

Title: The hunt for natural skin whitening agents.

Journal: International journal of molecular sciences 20091201

Title: Characterization and DNA-interaction studies of 1,1-dicyano-2,2-ethylene dithiolate Ni(II) mixed-ligand complexes with 2-amino-5-methyl thiazole, 2-amino-2-thiazoline and imidazole. Crystal structure of [Ni(i-MNT)(2a-5mt)(2)].

Journal: Bioorganic & medicinal chemistry 20090815

Title: 4-Fluoro-N-[3-(2-fluoro-phen-yl)-4-methyl-2,3-dihydro-2-thienyl-idene]benzamide.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: Two asymmetric syntheses of AMG 221, an inhibitor of 11beta-hydroxysteroid dehydrogenase type 1.

Journal: The Journal of organic chemistry 20090515

Title: Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A.

Journal: PloS one 20090101

Title: Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.

Journal: Bioorganic & medicinal chemistry 20080601

Title: (Z)-N-[3-(2-Methoxy-phen-yl)-4-phenyl-2,3-dihydro-thia-zol-2-yl-idene]-2-methyl-benzamide.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: (Z)-N-[3-(2-Methoxy-phen-yl)-4-phenyl-2,3-dihydro-thia-zol-2-yl-idene]-4-methyl-benzamide.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Bis(2-amino-2-thiazolinium) tetra-mu-formato-kappa8O:O'-bis[(formato-kappaO)copper(II)].

Journal: Acta crystallographica. Section C, Crystal structure communications 20070501

Title: A new 2-imino-1,3-thiazoline derivative, KHG22394, inhibits melanin synthesis in mouse B16 melanoma cells.

Journal: Biological & pharmaceutical bulletin 20070101

Title: It is 'thiazolidene-2-imine' and not imidazole-2-thione as the reaction product of 1-benzoyl-3-phenylthiourea with Br(2)/enolizable ketone.

Journal: Organic letters 20061109

Title: Synthesis, structural characterization and influence on the phagocytic activity of human neutrophils of thiazoline and thiazine derivative ligands and their zinc(II) complexes.

Journal: Journal of inorganic biochemistry 20061101

Title: Intra- and inter-molecular phosphoryl migration in phosphinothiazolines; precursors to polynuclear complexes and bimetallic coordination polymers.

Journal: Chemical communications (Cambridge, England) 20060807

Title: Evaluation of anti-inflammatory and antioxidant activities of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline.

Journal: Bioorganic & medicinal chemistry letters 20060415

Title: Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.

Journal: Bioorganic & medicinal chemistry 20060315

Title: Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds.

Journal: Veterinary parasitology 20051125

Title: In vivo anticancer, anti-inflammatory, and toxicity studies of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline. Crystal structure of [Cu(dien)(Br)(2a-2tzn)](Br)(H(2)O).

Journal: Journal of inorganic biochemistry 20051101

Title: Novel 2-aminothiazonaphthalimides as visible light activatable photonucleases: effects of intercalation, heterocyclic-fused area and side chains.

Journal: Bioorganic & medicinal chemistry letters 20050401

Title: Solid-phase synthesis of fungitoxic 2-imino-1,3-thiazolines.

Journal: Journal of combinatorial chemistry 20050101

Title: Novel rhodium-catalyzed reaction of thiazolidine derivatives with carbodiimides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20041119

Title: 2-Amino-2-thiazoline and its 1:1 organic salt with 2-naphthoxyacetic acid.

Journal: Acta crystallographica. Section C, Crystal structure communications 20040901

Title: 4,5-dialkylsubstituted 2-imino-1,3-thiazolidine derivatives as potent inducible nitric oxide synthase inhibitors.

Journal: Bioorganic & medicinal chemistry 20040801

Title: Synthesis and characterization of a new cobalt(II) complex with 2-(2-pyridyl)imino-N-(2-thiazolin-2-yl)thiazolidine (PyTT).

Journal: Bioinorganic chemistry and applications 20040101

Title: [2-Amino-2-thiazoline derivatives--a novel chemotype possessing muscarinomimetic effect].

Journal: Biomeditsinskaia khimiia 20030101

Title: Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors.

Journal: Journal of medicinal chemistry 20020620

Title: Chemistry of stable iminopropadienones, RN=C=C=C=O.

Journal: The Journal of organic chemistry 20020419

Title: Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.

Journal: Journal of inorganic biochemistry 20020101

Title: N-acetil-l-cysteine and 2-amino-2-thiiazoline N-acetyl-l-cysteinate as a possible cancer chemopreventive agents in murine models.

Journal: Acta biologica Hungarica 20020101

Title: [Study of the antiradical and radioprotective properties of S-containing compounds using the complex of in vitro test-systems].

Journal: Radiatsionnaia biologiia, radioecologiia 20020101

Title: Radioprotective effects of 2-iminothiazolidine derivatives against lethal doses of gamma radiation in mice.

Journal: Journal of radiation research 20011201

Title: Potentiation by aminoethylisothiourea of the extra-cellular Ca(2+) component of norepinephrine-induced contraction in rat femoral arteries.

Journal: Biochemical pharmacology 20010101

Title: Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas.

Journal: The Journal of biological chemistry 19941028

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