Name: Name:Acetamide, 2-[(2,3-dihydro-1H-inden-2-yl)amino]-, hydrochloride (1:1)
Brand: AABLOCKS
SKU: AA0028H1
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0028H1

Chemical Name: Acetamide, 2-[(2,3-dihydro-1H-inden-2-yl)amino]-, hydrochloride (1:1)

CAS Number: 202914-18-9

Molecular Formula: C11H15ClN2O

Molecular Weight: 226.7026

MDL Number: MFCD09840800

SMILES: NC(=O)CNC1Cc2c(C1)cccc2.Cl

Properties

Complexity: 203

Covalently-Bonded Unit Count: 2

Heavy Atom Count: 15

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 3

Rotatable Bond Count: 3

Literature fold

Title: Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain.

Journal: IDrugs : the investigational drugs journal20070901

Title: CHF3381, a N-methyl-D-aspartate receptor antagonist and monoamine oxidase-A inhibitor, attenuates secondary hyperalgesia in a human pain model.

Journal: The journal of pain : official journal of the American Pain Society20060801

Title: CHF3381, a novel antinociceptive agent, attenuates capsaicin-induced pain in rats.

Journal: European journal of pharmacology20050920

Title: Mechanistic pharmacokinetic and pharmacodynamic modeling of CHF3381 (2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide monohydrochloride), a novel N-methyl-D-aspartate antagonist and monoamine oxidase-A inhibitor in healthy subjects.

Journal: The Journal of pharmacology and experimental therapeutics20050501

Title: Steady-state pharmacokinetics and pharmacodynamics of CHF3381, a novel antineuropathic pain agent, in healthy subjects.

Journal: British journal of clinical pharmacology20050401

Title: CHF 3381.

Journal: Drugs in R&D20040101

Title: Antinociceptive activity of the N-methyl-D-aspartate receptor antagonist N-(2-Indanyl)-glycinamide hydrochloride (CHF3381) in experimental models of inflammatory and neuropathic pain.

Journal: The Journal of pharmacology and experimental therapeutics20030801

Title: Mechanisms of action of CHF3381 in the forebrain.

Journal: British journal of pharmacology20030801

Title: Safety, pharmacokinetics, and pharmacodynamics of CHF 3381, a novel N-methyl-D-aspartate antagonist, after single oral doses in healthy subjects.

Journal: Journal of clinical pharmacology20030801

Title: Neuroprotective activity of CHF3381, a putative N-methyl-D-aspartate receptor antagonist.

Journal: Neuroreport20021115

Title: Anticonvulsant preclinical profile of CHF 3381: dopaminergic and glutamatergic mechanisms.

Journal: Pharmacology, biochemistry, and behavior20010901

Title: Preclinical evaluation of CHF3381 as a novel antiepileptic agent.

Journal: Neuropharmacology20010601