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19829-79-9,MFCD00671539
Catalog No.:AA002BC6

19829-79-9 | 8-Hydroxyquinoline-7-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$23.00   $16.00
- +
5g
98%
in stock  
$84.00   $59.00
- +
25g
>98.0%(GC)(T)
in stock  
$310.00   $217.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002BC6
Chemical Name:
8-Hydroxyquinoline-7-carboxylic acid
CAS Number:
19829-79-9
Molecular Formula:
C10H7NO3
Molecular Weight:
189.1675
MDL Number:
MFCD00671539
SMILES:
OC(=O)c1ccc2c(c1O)nccc2
Properties
Properties
 
BP:
354.2°C at 760 mmHg  
Form:
Solid  
MP:
>253°C (dec.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
231  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.9  

Downstream Synthesis Route

[1]Nycz,JacekE.;Malecki,GrzegorzJ.[JournalofMolecularStructure,2013,vol.1032,p.159-168]

[2]Baret;Beguin;Boukhalfa;Caris;Laulhere;Pierre;Serratrice[JournaloftheAmericanChemicalSociety,1995,vol.117,#38,p.9760-9761]

[3]Caris;Baret;Pierre;Serratrice[Tetrahedron,1996,vol.52,#13,p.4659-4672]

[1]CurrentPatentAssignee:PFIZERINC-US6211376,2001,B1

[2]CurrentPatentAssignee:ALMIRALLSA-WO2011/80264,2011,A1Locationinpatent:Page/Pagecolumn27

[3]CurrentPatentAssignee:ALMIRALLSA-EP2345643,2011,A1Locationinpatent:Page/Pagecolumn12

19619-22-8    19829-79-9   
N-(2,4-dicyanophenyl)-8-hydroxyquinoline-7-carboxamide 

[1]BioorganicandMedicinalChemistryLetters,2019,vol.29,p.2307-2315

63069-50-1    19829-79-9   
N-(4-cyano-2-fluorophenyl)-8-hydroxyquinoline-7-carboxamide 

[1]BioorganicandMedicinalChemistryLetters,2019,vol.29,p.2307-2315

[1]BioorganicandMedicinalChemistryLetters,2019,vol.29,p.2307-2315

Literature

Title: Identification of influenza endonuclease inhibitors using a novel fluorescence polarization assay.

Journal: ACS chemical biology 20120316

Title: A structural and theoretical study of the intermolecular interactions in 8-hydroxyquinolinium-7-carboxylate monohydrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20110701

Title: Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20061101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: THE IN VITRO EFFECT OF 8-HYDROXYQUINOLINE DERIVATIVES ON STRAINS OF MYCOBACTERIUM TUBERCULOSIS.

Journal: Biochemical pharmacology 19640201

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