[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1
[1]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION;SENJUPHARMACEUTICALCO.,LTD.-EP1378247,2016,B1Locationinpatent:Paragraph0077
Title: Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats.
Journal: Current eye research 20111001
Title: Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries.
Journal: Japanese journal of ophthalmology 20110701
Title: Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells.
Journal: Molecular vision 20110101
Title: Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
Journal: Bioorganic & medicinal chemistry letters 20100601
Title: Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.
Journal: Journal of medicinal chemistry 20091112
Title: Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090601
Title: [Optic nerve regeneration in adult mammals].
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20080601
Title: A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.
Journal: Experimental neurology 20070501
Title: Hideki Tokushige, et al. Effects of Topical Administration of Y-39983, a Selective Rho-Associated Protein Kinase Inhibitor, on Ocular Tissues in Rabbits and Monkeys Invest. Ophthalmol. Vis. Sci. July 2007 vol. 48no. 7 3216-3222
Title: Tokushige H, et al. Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats. Curr Eye Res. 2011 Oct;36(10):964-70.
Title: Watabe H, et al. Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries.Jpn J Ophthalmol. 2011 Jul;55(4):411-7. Epub 2011 Jun 11.
