Title: Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.
Journal: Eukaryotic cell 20130201
Title: 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity.
Journal: ACS chemical biology 20121019
Title: PEG and ABA trigger methyl jasmonate accumulation to induce the MEP pathway and increase tanshinone production in Salvia miltiorrhiza hairy roots.
Journal: Physiologia plantarum 20121001
Title: Map-based cloning of zb7 encoding an IPP and DMAPP synthase in the MEP pathway of maize.
Journal: Molecular plant 20120901
Title: Development of petri net-based dynamic model for improved production of farnesyl pyrophosphate by integrating mevalonate and methylerythritol phosphate pathways in yeast.
Journal: Applied biochemistry and biotechnology 20120701
Title: Molecular cloning and functional characterization of Catharanthus roseus hydroxymethylbutenyl 4-diphosphate synthase gene promoter from the methyl erythritol phosphate pathway.
Journal: Molecular biology reports 20120501
Title: Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex.
Journal: Journal of experimental botany 20120301
Title: Structural studies on Mycobacterium tuberculosis DXR in complex with the antibiotic FR-900098.
Journal: Acta crystallographica. Section D, Biological crystallography 20120201
Title: Metabolic profiles and cDNA-AFLP analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib.
Journal: PloS one 20120101
Title: Functional expression of an orchid fragrance gene in Lactococcus lactis.
Journal: International journal of molecular sciences 20120101
Title: Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed.
Journal: PloS one 20120101
Title: Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways.
Journal: Journal of natural products 20111227
Title: Intraerythrocytic stages of Plasmodium falciparum biosynthesize vitamin E.
Journal: FEBS letters 20111215
Title: Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20111115
Title: Functional effect of grapevine 1-deoxy-D-xylulose 5-phosphate synthase substitution K284N on Muscat flavour formation.
Journal: Journal of experimental botany 20111101
Title: Role of reactive oxygen species and proline cycle in anthraquinone accumulation in Rubia tinctorum cell suspension cultures subjected to methyl jasmonate elicitation.
Journal: Plant physiology and biochemistry : PPB 20110701
Title: Induction of a longer term component of isoprene release in darkened aspen leaves: origin and regulation under different environmental conditions.
Journal: Plant physiology 20110601
Title: Structural and functional studies of mycobacterial IspD enzymes.
Journal: Acta crystallographica. Section D, Biological crystallography 20110501
Title: Structure of the E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase (GcpE) from Thermus thermophilus.
Journal: FEBS letters 20110204
Title: The methylerythritol phosphate (MEP) pathway for isoprenoid biosynthesis as a target for the development of new drugs against tuberculosis.
Journal: Current medicinal chemistry 20110101
Title: Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation.
Journal: PloS one 20110101
Title: Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata).
Journal: BMC genomics 20110101
Title: Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system.
Journal: Microbial cell factories 20110101
Title: [Investigation on traditional medicines of Guarany Indio and studies on diterpenes from Scoparia dulcis].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Title: Genetic variation of γ-tocopherol methyltransferase gene contributes to elevated α-tocopherol content in soybean seeds.
Journal: BMC plant biology 20110101
Title: Evidence of isoprenoid precursor toxicity in Bacillus subtilis.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: Supply of precursors for carotenoid biosynthesis in plants.
Journal: Archives of biochemistry and biophysics 20101201
Title: A single-molecule force spectroscopy nanosensor for the identification of new antibiotics and antimalarials.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101101
Title: Biosynthesis of the iridoid glucoside, lamalbid, in Lamium barbatum.
Journal: Phytochemistry 20101001
Title: The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae.
Journal: The Journal of antibiotics 20101001
Title: Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli.
Journal: Science (New York, N.Y.) 20101001
Title: Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03.
Journal: Plant physiology 20100701
Title: Homology modeling of Mycobacterium tuberculosis 2C-methyl-D-erythritol-4-phosphate cytidylyltransferase, the third enzyme in the MEP pathway for isoprenoid biosynthesis.
Journal: Journal of molecular modeling 20100601
Title: Analysis of 1-deoxy-D-xylulose 5-phosphate synthase activity in Grey poplar leaves using isotope ratio mass spectrometry.
Journal: Phytochemistry 20100601
Title: Virus-based microRNA expression for gene functional analysis in plants.
Journal: Plant physiology 20100601
Title: Disruption of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) gene results in albino, dwarf and defects in trichome initiation and stomata closure in Arabidopsis.
Journal: Cell research 20100601
Title: Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of deoxyxylulose phosphate reductoisomerase.
Journal: The Journal of organic chemistry 20100521
Title: Sponge-derived Streptomyces producing isoprenoids via the mevalonate pathway.
Journal: Journal of natural products 20100226
Title: The mitochondrial PPR protein LOVASTATIN INSENSITIVE 1 plays regulatory roles in cytosolic and plastidial isoprenoid biosynthesis through RNA editing.
Journal: The Plant journal : for cell and molecular biology 20100201
Title: Plant isoprenoid biosynthesis via the MEP pathway: in vivo IPP/DMAPP ratio produced by (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures.
Journal: FEBS letters 20100104
Title: Essential oil biosynthesis and regulation in the genus Cymbopogon.
Journal: Natural product communications 20100101
Title: A candidate gene association study on muscat flavor in grapevine (Vitis vinifera L.).
Journal: BMC plant biology 20100101
Title: Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.
Journal: Chemistry & biology 20091224
Title: Molecular characterization of the Oncidium orchid HDR gene encoding 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, the last step of the methylerythritol phosphate pathway.
Journal: Plant cell reports 20091001
Title: Isoprenoid biosynthesis via the MEP pathway: in vivo Mössbauer spectroscopy identifies a [4Fe-4S]2+ center with unusual coordination sphere in the LytB protein.
Journal: Journal of the American Chemical Society 20090923
Title: Identification and characterization of class 1 DXS gene encoding 1-deoxy-D-xylulose-5-phosphate synthase, the first committed enzyme of the MEP pathway from soybean.
Journal: Molecular biology reports 20090501
Title: Regulation of resin acid synthesis in Pinus densiflora by differential transcription of genes encoding multiple 1-deoxy-D-xylulose 5-phosphate synthase and 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase genes.
Journal: Tree physiology 20090501
Title: Complete blockage of the mevalonate pathway results in male gametophyte lethality.
Journal: Journal of experimental botany 20090501
Title: The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico.
Journal: Marine drugs 20090301
Title: Divergent regulation of terpenoid metabolism in the trichomes of wild and cultivated tomato species.
Journal: Plant physiology 20090101
Title: Accumulation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate in illuminated plant leaves at supraoptimal temperatures reveals a bottleneck of the prokaryotic methylerythritol 4-phosphate pathway of isoprenoid biosynthesis.
Journal: Plant, cell & environment 20090101
Title: A plastidial pathway for protein isoprenylation in tobacco cells.
Journal: The Plant cell 20090101
Title: The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells.
Journal: The Plant cell 20090101
Title: Unravelling the regulatory mechanisms that modulate the MEP pathway in higher plants.
Journal: Journal of experimental botany 20090101
Title: [2-(14)C-Methylerythritol 2,4-cyclodiphosphate incorporation into bacterial and plant isoprenoids].
Journal: Prikladnaia biokhimiia i mikrobiologiia 20090101
Title: Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).
Journal: PloS one 20090101
Title: Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway.
Journal: Journal of the American Chemical Society 20081224
Title: The plastidial MEP pathway: unified nomenclature and resources.
Journal: Trends in plant science 20081201
Title: Evolutionary diversification of plant shikimate kinase gene duplicates.
Journal: PLoS genetics 20081201
Title: Cloning and characterization of the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway genes of a natural-rubber producing plant, Hevea brasiliensis.
Journal: Bioscience, biotechnology, and biochemistry 20081101
Title: Identification and functional analysis of light-responsive unique genes and gene family members in rice.
Journal: PLoS genetics 20080801
Title: Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants.
Journal: The Journal of biological chemistry 20080725
Title: Contribution of hydroxymethylbutenyl diphosphate synthase to carotenoid biosynthesis in bacteria and plants.
Journal: Biochemical and biophysical research communications 20080704
Title: A cryptic algal group unveiled: a plastid biosynthesis pathway in the oyster parasite Perkinsus marinus.
Journal: Molecular biology and evolution 20080601
Title: Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
Journal: Chemistry & biodiversity 20080401
Title: Effects of feeding Spodoptera littoralis on lima bean leaves: IV. Diurnal and nocturnal damage differentially initiate plant volatile emission.
Journal: Plant physiology 20080301
Title: The dioxanone approach to (2S,3R)-2-C-methylerythritol 4-phosphate and 2,4-cyclodiphosphate, and various MEP analogues.
Journal: The Journal of organic chemistry 20071221
Title: Biosynthesis of isoprenoids: characterization of a functionally active recombinant 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) from Mycobacterium tuberculosis H37Rv.
Journal: Journal of biochemistry and molecular biology 20071130
Title: Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae).
Journal: Phytochemistry 20070801
Title: Isoprenoid biosynthesis authenticates the classification of the green alga Mesostigma viride as an ancient streptophyte.
Journal: Gene 20070701
Title: Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum.
Journal: Memorias do Instituto Oswaldo Cruz 20070601
Title: Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells.
Journal: International immunology 20070501
Title: A portfolio of plasmids for identification and analysis of carotenoid pathway enzymes: Adonis aestivalis as a case study.
Journal: Photosynthesis research 20070501
Title: Apocarotenoid biosynthesis in arbuscular mycorrhizal roots: contributions from methylerythritol phosphate pathway isogenes and tools for its manipulation.
Journal: Phytochemistry 20070101
Title: Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme.
Journal: Current pharmaceutical design 20070101
Title: The relationship between the methyl-erythritol phosphate pathway leading to emission of volatile isoprenoids and abscisic acid content in leaves.
Journal: Plant physiology 20060801
Title: Cloning and functional characterization of 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (GbMECT) gene from Ginkgo biloba.
Journal: Phytochemistry 20060701
Title: Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis.
Journal: Chemical & pharmaceutical bulletin 20060501
Title: Absence of substrate channeling between active sites in the Agrobacterium tumefaciens IspDF and IspE enzymes of the methyl erythritol phosphate pathway.
Journal: Biochemistry 20060321
Title: Molecular cloning and expression profile analysis of Ginkgo biloba DXS gene encoding 1-deoxy-D-xylulose 5-phosphate synthase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.
Journal: Planta medica 20060301
Title: A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1-deoxy-D-xylulose 5-phosphate synthase.
Journal: FEBS letters 20060206
Title: Cloning and expression of IspDF from Mesorhizobium loti. Characterization of a bifunctional protein that catalyzes non-consecutive steps in the methylerythritol phosphate pathway.
Journal: Biochimica et biophysica acta 20060101
Title: The Arabidopsis csb3 mutant reveals a regulatory link between salicylic acid-mediated disease resistance and the methyl-erythritol 4-phosphate pathway.
Journal: The Plant journal : for cell and molecular biology 20051001
Title: fldA is an essential gene required in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis.
Journal: FEBS letters 20050704
Title: Mechanistic studies with 2-C-methyl-D-erythritol 4-phosphate synthase from Escherichia coli.
Journal: Biochemistry 20050614
Title: Synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphoric acid analogues as alternate substrates for methylerythritol phosphate synthase.
Journal: The Journal of organic chemistry 20050318
Title: Evolution of the isoprene biosynthetic pathway in kudzu.
Journal: Plant physiology 20050201
Title: Pools of 14C-malic acid as a substrate for pyruvate production for the DOXP/MEP pathway of biosynthesis of carotenoids in chloroplasts.
Journal: Doklady. Biochemistry and biophysics 20050101
Title: The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum.
Journal: The Journal of biological chemistry 20041210
Title: Are iridoids in leaf beetle larvae synthesized de novo or derived from plant precursors? A methodological approach.
Journal: Isotopes in environmental and health studies 20040901
Title: Biosynthetic pathway for the C45 polyprenol, solanesol, in tobacco.
Journal: Bioscience, biotechnology, and biochemistry 20040901
Title: Rapid regulation of the methylerythritol 4-phosphate pathway during isoprene synthesis.
Journal: Plant physiology 20040801
Title: [Cloning and analysis of cDNA encoding key enzyme gene (dxr) of the non-MVA pathway in Taxus chinensis cells].
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040701
Title: Synthesis of (3R,4S)-3,4,5-trihydroxy-4-methylpentylphosphonic acid as a potential inhibitor of the nonmevalonate pathway.
Journal: Bioscience, biotechnology, and biochemistry 20040601
Title: CHLOROPLAST BIOGENESIS genes act cell and noncell autonomously in early chloroplast development.
Journal: Plant physiology 20040501
Title: Kinetic and chemical mechanism of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate isomeroreductase.
Journal: Biochemistry 20040413
Title: Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites.
Journal: The Plant journal : for cell and molecular biology 20040401
Title: Heterologous mevalonate production in Streptomyces lividans TK23.
Journal: Bioscience, biotechnology, and biochemistry 20040401
Title: The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes.
Journal: FEBS letters 20040312
Title: Synthesis of enantiopure 2-C-methyl-D-erythritol 4-phosphate and 2,4-cyclodiphosphate from D-arabitol.
Journal: Organic letters 20040108
Title: Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development.
Journal: The Plant cell 20040101
Title: The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs.
Journal: Current pharmaceutical design 20040101
Title: Isoprenoid biosynthesis via the MEP pathway. Synthesis of (3,4)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-D-xylulose 5-phosphate, the substrate of the 1-deoxy-D-xylulose 5-phosphate reducto-isomerase.
Journal: Organic & biomolecular chemistry 20031221
Title: A genetic basis for human gammadelta T-cell reactivity towards microbial pathogens.
Journal: Trends in immunology 20030801
Title: Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells.
Journal: The Journal of biological chemistry 20030718
Title: Microbial isoprenoid biosynthesis and human gammadelta T cell activation.
Journal: FEBS letters 20030605
Title: Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein.
Journal: FEBS letters 20030424
Title: High-performance liquid chromatography assay for 1-deoxy-D-xylulose 5-phosphate synthase activity using fluorescence detection.
Journal: Journal of chromatography. A 20030207
Title: Functional characterization of GcpE, an essential enzyme of the non-mevalonate pathway of isoprenoid biosynthesis.
Journal: FEBS letters 20021218
Title: LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis.
Journal: FEBS letters 20021218
Title: Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway.
Journal: Planta 20021201
Title: Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics.
Journal: Plant physiology 20021101
Title: Isoprenoid biosynthesis via the methylerythritol phosphate pathway. Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Journal: European journal of biochemistry 20020901
Title: Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.
Journal: Plant physiology 20020801
Title: Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol and 2-C-methyl-D-erythritol-4-phosphate.
Journal: The Journal of organic chemistry 20020726
Title: Accumulation of a potent gammadelta T-cell stimulator after deletion of the lytB gene in Escherichia coli.
Journal: Immunology 20020601
Title: Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: implications of a flexible loop movement upon substrate binding.
Journal: Journal of biochemistry 20020301
Title: Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
Journal: The Journal of biological chemistry 20020215
Title: E. coli MEP synthase: steady-state kinetic analysis and substrate binding.
Journal: Biochemistry 20020108
Title: Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway.
Journal: Phytochemistry 20020101
Title: Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coli.
Journal: FEBS letters 20011207
Title: Essential role of residue H49 for activity of Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase, the enzyme catalyzing the first step of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid Synthesis.
Journal: Biochemical and biophysical research communications 20011123
Title: Biosynthesis of terpenoids: efficient multistep biotransformation procedures affording isotope-labeled 2C-methyl-D-erythritol 4-phosphate using recombinant 2C-methyl-D-erythritol 4-phosphate synthase.
Journal: The Journal of organic chemistry 20011116
Title: Biosynthetic pathway of insect juvenile hormone III in cell suspension cultures of the sedge Cyperus iria.
Journal: Plant physiology 20011001
Title: Evidence for the biosynthesis of squalene via the methylerythritol phosphate pathway in a Streptomyces sp. obtained from a marine sediment.
Journal: The Journal of organic chemistry 20010907
Title: Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis.
Journal: Nature structural biology 20010701
Title: LytB, a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli.
Journal: FEBS letters 20010615
Title: Concise synthesis of (+)-2-C-methyl-D-erythritol-4-phosphate.
Journal: The Journal of organic chemistry 20010406
Title: Cutting edge: human gamma delta T cells are activated by intermediates of the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010315
Title: Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids.
Journal: Planta 20010201
Title: Identification of gcpE as a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis in Escherichia coli.
Journal: FEBS letters 20010119
Title: Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis.
Journal: The Biochemical journal 20010101
Title: Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway.
Journal: Acta biochimica Polonica 20010101
