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209216-23-9,MFCD00907887
Catalog No.:AA002K0D

209216-23-9 | Entecavir hydrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
5mg
98%
in stock  
$14.00   $10.00
- +
10mg
98%
in stock  
$17.00   $12.00
- +
50mg
98%
in stock  
$23.00   $16.00
- +
250mg
95%
in stock  
$80.00   $56.00
- +
1g
95%
in stock  
$191.00   $134.00
- +
5g
95%
in stock  
$762.00   $534.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002K0D
Chemical Name:
Entecavir hydrate
CAS Number:
209216-23-9
Molecular Formula:
C12H17N5O4
Molecular Weight:
295.2945
MDL Number:
MFCD00907887
SMILES:
OC[C@@H]1[C@@H](O)C[C@@H](C1=C)n1cnc2c1nc(N)[nH]c2=O.O
Properties
Computed Properties
 
Complexity:
480  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
2  

Downstream Synthesis Route

[1]Ho,MyoungJin;Lee,DaeRo;Im,SungHyun;Yoon,JeongA.;Shin,ChangYong;Kim,HyunJung;Jang,SunWoo;Choi,YoungWook;Han,YoungTaek;Kang,MyungJoo[InternationalJournalofPharmaceutics,2018,vol.543,#1-2,p.52-59]

[1]Ho,MyoungJin;Lee,DaeRo;Im,SungHyun;Yoon,JeongA.;Shin,ChangYong;Kim,HyunJung;Jang,SunWoo;Choi,YoungWook;Han,YoungTaek;Kang,MyungJoo[InternationalJournalofPharmaceutics,2018,vol.543,#1-2,p.52-59]

[1]Ho,MyoungJin;Lee,DaeRo;Im,SungHyun;Yoon,JeongA.;Shin,ChangYong;Kim,HyunJung;Jang,SunWoo;Choi,YoungWook;Han,YoungTaek;Kang,MyungJoo[InternationalJournalofPharmaceutics,2018,vol.543,#1-2,p.52-59]

[1]CurrentPatentAssignee:CHINESEACADEMYOFSCIENCES;ShanghaiInstituteofMateriaMedica(in:CAS)-CN112574269,2021,A

Literature

Title: Innaimo SF, et al. Identification of?BMS-200475?as a potent and selective inhibitor of hepatitis B virus. Antimicrob Agents Chemother. 1997 Jul;41(7):1444-8.

Title: Rivkin A, et al. A review of entecavir in the treatment of chronic hepatitis B infection. Curr Med Res Opin.?2005 Nov;21(11):1845-56.

Title: Genovesi EV, et al. Efficacy of the carbocyclic 2'-deoxyguanosine nucleoside?BMS-200475?in the woodchuck model of hepatitis B virus infection. Antimicrob Agents Chemother.?1998 Dec;42(12):3209-17.

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SDS
Tags:209216-23-9 Molecular Formula|209216-23-9 MDL|209216-23-9 SMILES|209216-23-9 Entecavir hydrate