Home Other Heterocycles 2103-64-2
2103-64-2,MFCD00150626
Catalog No.:AA002KLZ

2103-64-2 | 3',4',5',6'-Tetrahydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one

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1g
>85.0%(HPLC)
in stock  
$51.00   $36.00
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25g
>85.0%(HPLC)
in stock  
$435.00   $304.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002KLZ
Chemical Name:
3',4',5',6'-Tetrahydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
CAS Number:
2103-64-2
Molecular Formula:
C20H12O7
Molecular Weight:
364.3051
MDL Number:
MFCD00150626
SMILES:
O=C1OC2(c3c1cccc3)c1ccc(c(c1Oc1c2ccc(c1O)O)O)O
Properties
Properties
 
BP:
687.4°C at 760 mmHg  
Form:
Solid  
MP:
>300℃  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
579  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
XLogP3:
2.7  

Literature

Title: Pharmacological profile of phosphatidylinositol 3-kinases and related phosphatidylinositols mediating endothelin(A) receptor-operated native TRPC channels in rabbit coronary artery myocytes.

Journal: British journal of pharmacology 20120801

Title: Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition.

Journal: International journal of oncology 20120701

Title: G-protein βγ subunits in vasorelaxing and anti-endothelinergic effects of calcitonin gene-related peptide.

Journal: British journal of pharmacology 20120501

Title: Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.

Journal: American journal of respiratory cell and molecular biology 20111201

Title: Direct-reversible binding of small molecules to G protein βγ subunits.

Journal: Biochimica et biophysica acta 20110901

Title: Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110105

Title: Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure.

Journal: Circulation research 20100820

Title: Single DNA molecule stretching measures the activity of chemicals that target the HIV-1 nucleocapsid protein.

Journal: Analytical biochemistry 20061115

Title: Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity.

Journal: Biochemical and biophysical research communications 20020906

Title: Specificity in structure-based drug design: identification of a novel, selective inhibitor of Pneumocystis carinii dihydrofolate reductase.

Journal: Proteins 19970901

Title: Sanz G, et al. Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30;10(1):541.

Title: Lillie RD, et al. Hematoxylin substitutes: gallein as a biological stain. Stain Technol. 1974 Nov;49(6):339-46.

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Tags:2103-64-2 Molecular Formula|2103-64-2 MDL|2103-64-2 SMILES|2103-64-2 3',4',5',6'-Tetrahydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one |Heterocyclic_Building_Blocks