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2114-02-5,MFCD00014472
Catalog No.:AA002L9D

2114-02-5 | Amidinothiourea

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10g
98%
in stock  
$6.00   $4.00
- +
25g
98%
in stock  
$8.00   $6.00
- +
100g
98%
in stock  
$22.00   $15.00
- +
500g
98%
in stock  
$74.00   $52.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002L9D
Chemical Name:
Amidinothiourea
CAS Number:
2114-02-5
Molecular Formula:
C2H6N4S
Molecular Weight:
118.1608
MDL Number:
MFCD00014472
SMILES:
NN=CNC(=S)N
NSC Number:
55743
Properties
Properties
 
BP:
310.5°C at 760 mmHg  
Form:
Solid  
MP:
171-173 °C(lit.)  
Refractive Index:
1.5605 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
102  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
3  
XLogP3:
-1.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:NATIONALHEALTHRESEARCHINSTITUTES-US2004/157883,2004,A1Locationinpatent:Page13

[2]Beyer,H.;Hantschel,H.[ChemischeBerichte,1962,vol.95,p.893-901]

[1]Stolpovskaya;Kruzhilin;Zorina;Shikhaliev,Kh.S.;Ledeneva;Kosheleva;Vandyshev,D.Yu.[RussianJournalofOrganicChemistry,2019,vol.55,#9,p.1322-1328][Zh.Org.Khim.,2019,vol.55,#9,p.1406-1414,9]

[2]CurrentPatentAssignee:NATIONALHEALTHRESEARCHINSTITUTES-US2004/157883,2004,A1Locationinpatent:Page12;13;

[3]Locationinpatent:experimentalpartLi,Wen-Tai;Hwang,Der-Ren;Song,Jen-Shin;Chen,Ching-Ping;Chen,Tung-Wei;Lin,Chi-Hung;Chuu,Jiunn-Jye;Lien,Tzu-Wen;Hsu,Tsu-An;Huang,Chen-Lung;Tseng,Huan-Yi;Lin,Chu-Chung;Lin,Heng-Liang;Chang,Chung-Ming;Chao,Yu-Sheng;Chen,Chiung-Tong[InvestigationalNewDrugs,2012,vol.30,#1,p.164-175]

[4]Beyer,H.;Hantschel,H.[ChemischeBerichte,1962,vol.95,p.893-901]

[1]Shikhaliev;Kryl'skaya;Potapov[RussianChemicalBulletin,2006,vol.55,#6,p.1089-1090]

[2]Kempson,James;Pitts,WilliamJ.;Barbosa,Joseph;Guo,Junqing;Omotoso,Omonike;Watson,Andrew;Stebbins,Karen;Starling,GaryC.;Dodd,JohnH.;Barrish,JoelC.;Felix,Raymond;Fischer,Karl[BioorganicandMedicinalChemistryLetters,2005,vol.15,#7,p.1829-1833]

[3]Locationinpatent:schemeortableGuo,Junqing;Watson,Andrew;Kempson,James;Carlsen,Marianne;Barbosa,Joseph;Stebbins,Karen;Lee,Deborah;Dodd,John;Nadler,StevenG.;McKinnon,Murray;Barrish,Joel;Pitts,WilliamJ.[BioorganicandMedicinalChemistryLetters,2009,vol.19,#7,p.1935-1938]

[4]Stolpovskaya;Kruzhilin;Zorina;Shikhaliev,Kh.S.;Ledeneva;Kosheleva;Vandyshev,D.Yu.[RussianJournalofOrganicChemistry,2019,vol.55,#9,p.1322-1328][Zh.Org.Khim.,2019,vol.55,#9,p.1406-1414,9]

[5]Beyer,H.;Hantschel,H.[ChemischeBerichte,1962,vol.95,p.893-901]

2114-02-5    21742-00-7   
(4-trifluoromethylphenyl)methylamidinoisothioureahydrochloride 

[1]JournalofMedicinalChemistry,2006,vol.49,p.6977-6986

[1]CurrentPatentAssignee:VYOMETHERAPEUTICSLIMITED-WO2017/17631,2017,A2Locationinpatent:Paragraph00349

[2]CurrentPatentAssignee:ASTRAZENECAPLC;OTSUKAHOLDINGSCOLTD-WO2007/120096,2007,A1Locationinpatent:Page/Pagecolumn50-51

Literature

Title: Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants.

Journal: Bulletin of experimental biology and medicine 20120701

Title: Microwave-assisted Heterocyclic Dicarboxylic Acids as Potential Antifungal and Antibacterial Drugs.

Journal: Indian journal of pharmaceutical sciences 20110101

Title: Electronic structure and reactivity of guanylthiourea: a quantum chemical study.

Journal: Journal of computational chemistry 20100430

Title: Supramolecular motifs in the first structures of organic carboxylate salts of 1-(diaminomethylene)thiourea (HATU).

Journal: Acta crystallographica. Section C, Crystal structure communications 20090801

Title: Products of the interaction of (1-diaminomethylene)thiourea with hydrofluoric acid.

Journal: Acta crystallographica. Section C, Crystal structure communications 20090501

Title: Products of the oxidation of 1-(diaminomethylene)thiourea with hydrogen peroxide.

Journal: Acta crystallographica. Section C, Crystal structure communications 20081101

Title: Hydrogen-bonded networks in crystals of 1-(diaminomethylene)thiouron-1-ium perchlorate, hydrogen sulfate, dihydrogen phosphate and dihydrogen arsenate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20080601

Title: 1-(Diaminomethylene)thiourea: a tautomer of 2-imino-4-thiobiuret.

Journal: Acta crystallographica. Section C, Crystal structure communications 20080301

Title: [Neurophysiological analysis of the effects of antihypoxic versus psychotropic agents].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20020101

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