Home Other Building Blocks 2295-35-4
2295-35-4,MFCD00049351
Catalog No.:AA002LKT

2295-35-4 | Pyrrolidine-2-thione

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$54.00   $38.00
- +
5g
98%
in stock  
$139.00   $97.00
- +
100g
95%
in stock  
$2,472.00   $1,731.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002LKT
Chemical Name:
Pyrrolidine-2-thione
CAS Number:
2295-35-4
Molecular Formula:
C4H7NS
Molecular Weight:
101.1701
MDL Number:
MFCD00049351
SMILES:
S=C1CCCN1
Properties
Properties
 
Form:
Solid  
MP:
110-112°C  
Storage:
Room Temperature;Light sensitive;Inert atmosphere;  

Computed Properties
 
Complexity:
69.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  

Downstream Synthesis Route

[1]BulletinoftheChemicalSocietyofJapan,1970,vol.43,p.453-455

[1]Padwa;Harring;Hertzog;Nadler[Synthesis,1994,#9,p.993-1004]

[2]Padwa,Albert;Kinder,FredericR.;Nadler,WilliamR.;Zhi,Lin[Heterocycles,1993,vol.35,#1,p.367-383]

[1]Shang,Jing;Thombare,VarshaJ.;Charron,CarlieL.;Wille,Uta;Hutton,CraigA.[Chemistry-AEuropeanJournal,2021,vol.27,#5,p.1620-1625]

[2]Locationinpatent:experimentalpartBergman,Jan;Pettersson,Birgitta;Hasimbegovic,Vedran;Svensson,PerH.[JournalofOrganicChemistry,2011,vol.76,#6,p.1546-1553]

[3]Robinson,RossS.;Dovey,MartinC.;Gravestock,David[EuropeanJournalofOrganicChemistry,2005,#3,p.505-511]

[4]Koduri,NagaDurgarao;Scott,Halee;Hileman,Bethany;Cox,JustinD.;Coffin,Michael;Glicksberg,Lindsay;Hussaini,SyedR.[OrganicLetters,2012,vol.14,#2,p.440-443]

[5]Zaorska,Ewelina;Hutsch,Tomasz;Gawryś-Kopczyńska,Marta;Ostaszewski,Ryszard;Ufnal,Marcin;Koszelewski,Dominik[BioorganicChemistry,2019,vol.88]

[6]Charette,AndreB.;Grenon,Michel[JournalofOrganicChemistry,2003,vol.68,#14,p.5792-5794]

[7]Locationinpatent:experimentalpartNeto,BrennoA.D.;Lapis,AlexandreA.M.;Bernd,AlinneB.;Russowsky,Dennis[Tetrahedron,2009,vol.65,#12,p.2484-2496]

[8]Brillon,Denis[SyntheticCommunications,1990,vol.20,#19,p.3085-3095]

[9]Locationinpatent:experimentalpartLagiakos,HelenRachel;Walker,Ashley;Aguilar,Marie-Isabel;Perlmutter,Patrick[TetrahedronLetters,2011,vol.52,#40,p.5131-5132]

[10]Curphey,ThomasJ.[JournalofOrganicChemistry,2002,vol.67,#18,p.6461-6473]

[11]Yokoyama,Masataka;Menjo,Yasuhiro;Ubukata,Makoto;Irie,Masakazu;Watanabe,Mikari;Togo,Hideo[BulletinoftheChemicalSocietyofJapan,1994,vol.67,#8,p.2219-2226]

[12]Lacroix,Simon;Rixhon,Vinciane;Marchand-Brynaert,Jacqueline[Synthesis,2006,#14,p.2327-2334]

[13]Zhang,Xiaoxiang;Teo,WanTeng;Sally;Chan,PhilipWaiHong[JournalofOrganicChemistry,2010,vol.75,#18,p.6290-6293]

[14]Padwa,Albert;Kinder,FredericR.;Nadler,WilliamR.;Zhi,Lin[Heterocycles,1993,vol.35,#1,p.367-383]

[15]Padwa;Harring;Hertzog;Nadler[Synthesis,1994,#9,p.993-1004]

[16]CurrentPatentAssignee:FUJIANAKEYLINKBIOTECHNOLOGY-US2019/375728,2019,A1Locationinpatent:Paragraph0178

[17]CurrentPatentAssignee:FUJIANAKEYLINKBIOTECHNOLOGY-EP3572412,2019,A1Locationinpatent:Paragraph0082-0083

[18]Peters,Rene;Althaus,Martin;Nagy,Anne-Laure[OrganicandBiomolecularChemistry,2006,vol.4,#3,p.498-509]

[19]Wipf,Peter;Jenny,Christjohannes;Heimgartner,Heinz[HelveticaChimicaActa,1987,vol.70,p.1001-1011]

[20]Sakoda,Masako;Usui,Kenji;Ishizuka,Kozo;Harada,Nobuyuki;Ono,Hiroshi;etal.[Phytochemistry,1993,vol.32,#6,p.1371-1374]

[21]Anbazhagan,Mariappan;Dixit,ArunN.;Rajappa,Srinivasachari[JournaloftheChemicalSociety.PerkintransactionsI,1997,#16,p.2421-2424]

[22]CurrentPatentAssignee:WUXIAPPTECCO.,LTD.-EP3719012,2020,A1Locationinpatent:Paragraph0170-0171

2295-35-4    1056477-06-5   
2-<(3,4-Dihydro-3H-pyrrol-2-yl)thio>-1-cyclohexanon 

[1]Tressl,Roland;Helak,Bernd;Spengler,Kurt;Schroeder,Andreas;Rewicki,Dieter[LiebigsAnnalenderChemie,1985,#10,p.2017-2027]

[1]Padwa,Albert;Kinder,FredericR.;Nadler,WilliamR.;Zhi,Lin[Heterocycles,1993,vol.35,#1,p.367-383]

Literature

Title: Synthesis and evaluation of novel modified γ-lactam prostanoids as EP4 subtype-selective agonists.

Journal: Bioorganic & medicinal chemistry 20120115

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