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22978-25-2,MFCD01215270
Catalog No.:AA002LOM

22978-25-2 | 2-chloro-5-nitro-N-phenylbenzamide

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5mg
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10mg
98%
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1g
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$41.00   $29.00
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5g
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25g
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100g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002LOM
Chemical Name:
2-chloro-5-nitro-N-phenylbenzamide
CAS Number:
22978-25-2
Molecular Formula:
C13H9ClN2O3
Molecular Weight:
276.6752
MDL Number:
MFCD01215270
SMILES:
Clc1ccc(cc1C(=O)Nc1ccccc1)[N+](=O)[O-]
Properties
Properties
 
BP:
360.9±32.0°C at 760 mmHg  
Form:
Solid  
MP:
171-175 °C(lit.)  
Solubility:
DMSO: 26 mg/mL, soluble  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
339  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
3.3  

Literature

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Title: Bisphenol A and its derivatives decrease expression of chemerin, which reverses its stimulatory action in ovarian cancer cells.

Journal: Toxicology letters 20180701

Title: Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR-γ and subsequent expression of HGF in colons.

Journal: Toxicology and applied pharmacology 20180315

Title: ONTD induces growth arrest and apoptosis of human hepatoma Bel-7402 cells though a peroxisome proliferator-activated receptor γ-dependent pathway.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: From the Cover: l-Carnitine via PPARγ- and Sirt1-Dependent Mechanisms Attenuates Epithelial-Mesenchymal Transition and Renal Fibrosis Caused by Perfluorooctanesulfonate.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20171201

Title: Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma.

Journal: Toxicology and applied pharmacology 20170901

Title: Mono-2-ethylhexyl phthalate inhibits human extravillous trophoblast invasion via the PPARγ pathway.

Journal: Toxicology and applied pharmacology 20170715

Title: 6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ.

Journal: Oncotarget 20170627

Title: CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170401

Title: Bisphenol A and its derivatives tetrabromobisphenol A and tetrachlorobisphenol A induce apelin expression and secretion in ovarian cancer cells through a peroxisome proliferator-activated receptor gamma-dependent mechanism.

Journal: Toxicology letters 20170305

Title: Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ.

Journal: Toxicology and applied pharmacology 20170201

Title: Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma.

Journal: Frontiers in pharmacology 20170101

Title: PPAR-γ activation attenuates deltamethrin-induced apoptosis by regulating cytosolic PINK1 and inhibiting mitochondrial dysfunction.

Journal: Toxicology letters 20161017

Title: Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro.

Journal: Environmental science & technology 20161004

Title: Bisphenol S- and bisphenol A-induced adipogenesis of murine preadipocytes occurs through direct peroxisome proliferator-activated receptor gamma activation.

Journal: International journal of obesity (2005) 20161001

Title: Chrysin, a PPAR-γ agonist improves myocardial injury in diabetic rats through inhibiting AGE-RAGE mediated oxidative stress and inflammation.

Journal: Chemico-biological interactions 20160425

Title: Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.

Journal: Oncotarget 20160301

Title: Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis.

Journal: Scientific reports 20160101

Title: Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury From SO2 Inhalation via PPARγ Pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20151001

Title: Peroxisome proliferator-activated receptor γ controls ingestive behavior, agouti-related protein, and neuropeptide Y mRNA in the arcuate hypothalamus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20150318

Title: Involvement of PPARγ in emodin-induced HK-2 cell apoptosis.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150201

Title: Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.

Journal: International journal of molecular sciences 20150101

Title: Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer's Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation.

Journal: CNS & neurological disorders drug targets 20150101

Title: Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells.

Journal: PloS one 20150101

Title: Hesperidin blunts streptozotocin-isoproternol induced myocardial toxicity in rats by altering of PPAR-γ receptor.

Journal: Chemico-biological interactions 20140805

Title: Rosiglitazone inhibits chlorpyrifos-induced apoptosis via modulation of the oxidative stress and inflammatory response in SH-SY5Y cells.

Journal: Toxicology and applied pharmacology 20140715

Title: Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.

Journal: Antioxidants & redox signaling 20140520

Title: Long term intake of 0.1% ethanol decreases serum adiponectin by suppressing PPARγ expression via p38 MAPK pathway.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301

Title: Hydroxysafflor yellow A of Carthamus tinctorius attenuates lung injury of aged rats exposed to gasoline engine exhaust by down-regulating platelet activation.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20140215

Title: Chrysin and luteolin alleviate vascular complications associated with insulin resistance mainly through PPAR-γ activation.

Journal: The American journal of Chinese medicine 20140101

Title: Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20131201

Title: Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors.

Journal: European journal of pharmacology 20131115

Title: Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib.

Journal: Journal of lipid research 20131101

Title: A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia.

Journal: Toxicology and applied pharmacology 20131101

Title: Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo.

Journal: Toxicology and applied pharmacology 20130515

Title: Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine.

Journal: European journal of pharmacology 20130105

Title: Effects of parabens on adipocyte differentiation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130101

Title: COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.

Journal: Molecular cancer therapeutics 20130101

Title: Induction of the fatty acid 2-hydroxylase (FA2H) gene by Δ(9)-tetrahydrocannabinol in human breast cancer cells.

Journal: The Journal of toxicological sciences 20130101

Title: Sodium dodecyl sulfate and sodium dodecyl benzenesulfonate are ligands for peroxisome proliferator-activated receptor γ.

Journal: The Journal of toxicological sciences 20130101

Title: Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

Journal: The Journal of biological chemistry 20121102

Title: Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects.

Journal: European journal of pharmacology 20121005

Title: Nanoparticle-mediated delivery of pioglitazone enhances therapeutic neovascularization in a murine model of hindlimb ischemia.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20121001

Title: Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening.

Journal: The Journal of biological chemistry 20120921

Title: Activation of PPARγ by restores mast cell numbers and reactivity in alloxan-diabetic rats by reducing the systemic glucocorticoid levels.

Journal: European journal of pharmacology 20120915

Title: 15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells.

Journal: The Journal of pharmacology and experimental therapeutics 20120901

Title: A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4.

Journal: Toxicology and applied pharmacology 20120901

Title: Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.

Journal: Investigative ophthalmology & visual science 20120831

Title: Activation of adipogenesis by lipocalin-type prostaglandin D synthase-generated Δ¹²-PGJ₂ acting through PPARγ-dependent and independent pathways.

Journal: Gene 20120815

Title: The endocrine disruptor diethylstilbestrol induces adipocyte differentiation and promotes obesity in mice.

Journal: Toxicology and applied pharmacology 20120815

Title: Possible involvement of PPAR-gamma receptor and nitric oxide pathway in the anticonvulsant effect of acute pioglitazone on pentylenetetrazole-induced seizures in mice.

Journal: Epilepsy research 20120801

Title: 15-Deoxy-Δ(12,14)-prostaglandin J(2) attenuates the biological activities of monocyte/macrophage cell lines.

Journal: European journal of cell biology 20120801

Title: Different roles of PPAR-γ activity on physiological and pathological alteration after myocardial ischemia.

Journal: Journal of cardiovascular pharmacology 20120801

Title: Estrogen improves vascular function via peroxisome-proliferator-activated-receptor-γ.

Journal: Journal of molecular and cellular cardiology 20120801

Title: Pioglitazone, a PPAR-γ activator, attenuates the severity of cerulein-induced acute pancreatitis by modulating early growth response-1 transcription factor.

Journal: Translational research : the journal of laboratory and clinical medicine 20120801

Title: Cardioprotection from oxidative stress in the newborn heart by activation of PPARγ is mediated by catalase.

Journal: Free radical biology & medicine 20120715

Title: Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.

Journal: European journal of pharmacology 20120615

Title: Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease.

Journal: Experimental neurology 20120601

Title: Hyperbaric oxygen preconditioning protects cortical neurons against oxygen-glucose deprivation injury: role of peroxisome proliferator-activated receptor-gamma.

Journal: Brain research 20120503

Title: Monascus-fermented metabolite monascin suppresses inflammation via PPAR-γ regulation and JNK inactivation in THP-1 monocytes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Title: Peroxisome proliferator-activated receptor-γ activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20120501

Title: Effects of bacterial and presystemic nitroreductase metabolism of 2-chloro-5-nitro-N-phenylbenzamide on its mutagenicity and bioavailability.

Journal: Chemico-biological interactions 20120415

Title: PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney.

Journal: Biogerontology 20120401

Title: Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma.

Journal: Acta neuropathologica 20120401

Title: Eicosapentaenoic acid disrupts the balance between Tregs and IL-17+ T cells through PPARγ nuclear receptor activation and protects cardiac allografts.

Journal: The Journal of surgical research 20120301

Title: Peroxisome proliferating activating receptor gamma-independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinediones.

Journal: Fertility and sterility 20120301

Title: Drug-targeted inhibition of peroxisome proliferator-activated receptor-gamma enhances the chemopreventive effect of anti-estrogen therapy.

Journal: Oncotarget 20120301

Title: PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.

Journal: The Journal of allergy and clinical immunology 20120201

Title: Telmisartan exerts renoprotective actions via peroxisome proliferator-activated receptor-γ/hepatocyte growth factor pathway independent of angiotensin II type 1 receptor blockade.

Journal: Hypertension (Dallas, Tex. : 1979) 20120201

Title: Angiogenic response of advanced glycation end products (AGEs) involves PPARgamma.

Journal: Indian journal of biochemistry & biophysics 20120201

Title: Cell death is induced by ciglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, independently of PPARγ in human glioma cells.

Journal: Biochemical and biophysical research communications 20120106

Title: Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPARγ-LXRα-ABCA1 pathway.

Journal: The Journal of nutritional biochemistry 20120101

Title: Inhibition of lymphoma cell proliferation by peroxisomal proliferator-activated receptor-γ ligands via Wnt signaling pathway.

Journal: Cell biochemistry and biophysics 20120101

Title: Synthesis and evaluation of 18F-labeled PPARγ antagonists.

Journal: Nuclear medicine and biology 20120101

Title: Biochanin A ameliorates the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by a PPARγ-dependent pathway.

Journal: Molecular medicine reports 20120101

Title: The influence of peroxisome proliferator-activated receptor γ(1) during differentiation of mouse embryonic stem cells to neural cells.

Journal: Differentiation; research in biological diversity 20120101

Title: Berberine ameliorates COX-2 expression in rat small intestinal mucosa partially through PPARγ pathway during acute endotoxemia.

Journal: International immunopharmacology 20120101

Title: Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

Journal: PloS one 20120101

Title: Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease.

Journal: Journal of neuroinflammation 20120101

Title: Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.

Journal: PloS one 20120101

Title: Mycophenolic acid induces ATP-binding cassette transporter A1 (ABCA1) expression through the PPARγ-LXRα-ABCA1 pathway.

Journal: Biochemical and biophysical research communications 20111104

Title: Troglitazone-activated PPARγ inhibits LPS-induced lung alveolar type II epithelial cells injuries via TNF-α.

Journal: Molecular biology reports 20111101

Title: Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism.

Journal: Journal of hepatology 20111101

Title: Bezafibrate restores the inhibition of FSH-induced follicular development and steroidogenesis by tumor necrosis factor-alpha through peroxisome proliferator-activated receptor-gamma pathway in an in vitro mouse preantral follicle culture.

Journal: Biology of reproduction 20111101

Title: Preventive action of curcumin in experimental acute pancreatitis in mouse.

Journal: The Indian journal of medical research 20111101

Title: Antidepressant-like effect of pioglitazone in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.

Journal: Behavioural brain research 20111031

Title: Activation of Trim17 by PPARγ is involved in di(2-ethylhexyl) phthalate (DEHP)-induced apoptosis on Neuro-2a cells.

Journal: Toxicology letters 20111030

Title: Early atheroma-derived agonists of peroxisome proliferator-activated receptor-γ trigger intramedial angiogenesis in a smooth muscle cell-dependent manner.

Journal: Circulation research 20111014

Title: The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes.

Journal: The Journal of steroid biochemistry and molecular biology 20111001

Title: Activation of peroxisome proliferators-activated receptor δ (PPARδ) promotes blastocyst hatching in mice.

Journal: Molecular human reproduction 20111001

Title: Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia.

Journal: Fitoterapia 20111001

Title: Peroxisome proliferator-activated receptor γ (PPARγ) plays a critical role in the development of TGFβ resistance of H460 cell.

Journal: Cellular signalling 20111001

Title: PPARgamma-independent increase in glucose uptake and adiponectin abundance in fat cells.

Journal: Endocrinology 20111001

Title: Trans-10, cis-12 conjugated linoleic acid and the PPAR-γ agonist rosiglitazone attenuate lipopolysaccharide-induced TNF-α production by bovine immune cells.

Journal: Domestic animal endocrinology 20111001

Title: [Effects of rosiglitazone on peroxisome proliferator activated receptor-γ pathway in patients with chronic obstructive pulmonary disease].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20111001

Title: 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma.

Journal: Journal of cellular biochemistry 20110901

Title: Relaxin causes selective outward remodeling of brain parenchymal arterioles via activation of peroxisome proliferator-activated receptor-γ.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110901

Title: Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice.

Journal: American journal of physiology. Heart and circulatory physiology 20110901

Title: Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.

Journal: Biochemical pharmacology 20110901

Title: Omega-3 fatty acids attenuate constitutive and insulin-induced CD36 expression through a suppression of PPAR α/γ activity in microvascular endothelial cells.

Journal: Thrombosis and haemostasis 20110901

Title: Selenium levels affect the IL-4-induced expression of alternative activation markers in murine macrophages.

Journal: The Journal of nutrition 20110901

Title: Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.

Journal: Nature medicine 20110828

Title: Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ.

Journal: British journal of pharmacology 20110801

Title: Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.

Journal: Environmental health perspectives 20110801

Title: Rosiglitazone protects neuroblastoma cells against advanced glycation end products-induced injury.

Journal: Acta pharmacologica Sinica 20110801

Title: Troglitazone induced apoptosis via PPARγ activated POX-induced ROS formation in HT29 cells.

Journal: Biomedical and environmental sciences : BES 20110801

Title: Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells.

Journal: Circulation 20110712

Title: Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity.

Journal: Biochemical and biophysical research communications 20110708

Title: 15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways.

Journal: Biochemical and biophysical research communications 20110708

Title: Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20110701

Title: Plasma rich in quercetin metabolites induces G2/M arrest by upregulating PPAR-γ expression in human A549 lung cancer cells.

Journal: Planta medica 20110701

Title: Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression.

Journal: Analytical biochemistry 20110701

Title: Peroxisome proliferator-activated receptor γ-induced T cell apoptosis reduces survival during polymicrobial sepsis.

Journal: American journal of respiratory and critical care medicine 20110701

Title: Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.

Journal: Biochimica et biophysica acta 20110701

Title: [Peroxisome proliferator activated receptor gamma activation and overexpression prevent hepatocellular apoptosis of nutritional fibrotic steatohepatitis in mice].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20110701

Title: Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPARγ-independent mechanism.

Journal: Cancer biology & therapy 20110615

Title: Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells.

Journal: Experimental cell research 20110610

Title: Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles.

Journal: The European respiratory journal 20110601

Title: Double antioxidant activities of rosiglitazone against high glucose-induced oxidative stress in hepatocyte.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110601

Title: Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels.

Journal: Molecular pharmacology 20110601

Title: Importance of inverse correlation between ALDH3A1 and PPARγ in tumor cells and tissue regeneration.

Journal: Chemico-biological interactions 20110530

Title: Electrophilic fatty acids regulate matrix metalloproteinase activity and expression.

Journal: The Journal of biological chemistry 20110506

Title: Rubus suavissimus S. Lee extract increases early adipogenesis in 3T3-L1 preadipocytes.

Journal: Journal of natural medicines 20110401

Title: Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.

Journal: Cardiovascular research 20110401

Title: Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking.

Journal: Biological psychiatry 20110401

Title: Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.

Journal: The Journal of clinical investigation 20110401

Title: Peroxisome proliferator-activated receptor-gamma agonist induces regulatory T cells in a murine model of allergic rhinitis.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20110401

Title: HO-1 Induced by Cilostazol Protects Against TNF-α-associated Cytotoxicity via a PPAR-γ-dependent Pathway in Human Endothelial Cells.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20110401

Title: Role of different types of potassium channels and peroxisome proliferator-activated receptors γ in the antidepressant-like activity of bis selenide in the mouse tail suspension test.

Journal: Neuroscience letters 20110303

Title: The short chain fatty acid sodium butyrate regulates the induction of CD1a in developing dendritic cells.

Journal: Immunobiology 20110301

Title: Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice.

Journal: Scandinavian journal of gastroenterology 20110301

Title: Peroxisome-proliferator-activated receptor γ mediates the second window of anaesthetic-induced preconditioning.

Journal: Experimental physiology 20110301

Title: Phospholipidosis induced by PPARγ signaling in human bronchial epithelial (BEAS-2B) cells exposed to amiodarone.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110301

Title: IL-33 is expressed in human osteoblasts, but has no direct effect on bone remodeling.

Journal: Cytokine 20110301

Title: [PPARγ up-regulates TGFβ/smad signal pathway repressor c-Ski].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20110225

Title: Effect of Ganoderma lucidum extract on adipocyte differentiation and adiponectin gene expression in the murine pre-adipocyte cell line, 3T3-L1.

Journal: Phytotherapy research : PTR 20110201

Title: Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells.

Journal: Prostaglandins & other lipid mediators 20110201

Title: Inhibitory effect of rosiglitazone on the acid-induced intracellular generation of hydrogen peroxide in cultured feline esophageal epithelial cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110201

Title: Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells.

Journal: Cancer letters 20110128

Title: [Effects of soluble epoxide hydrolase inhibitors on lipid metabolism and secretive functions of adipocytes].

Journal: Zhonghua yi xue za zhi 20110111

Title: Role of PPARγ in the salutary effects of 17β-estradiol on Kupffer cell cytokine production following trauma-hemorrhage.

Journal: Journal of cellular physiology 20110101

Title: Duration and magnitude of extracellular signal-regulated protein kinase phosphorylation determine adipogenesis or osteogenesis in human bone marrow-derived stem cells.

Journal: Yonsei medical journal 20110101

Title: Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo.

Journal: Experimental biology and medicine (Maywood, N.J.) 20110101

Title: Inhibitory effects of rosiglitazone on lipopolysaccharide-induced inflammation in a murine model and HK-2 cells.

Journal: American journal of nephrology 20110101

Title: Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery.

Journal: Pharmacology 20110101

Title: Telmisartan prevents VCAM-1 induction and monocytic cell adhesion to endothelium exposed to non-uniform shear stress and TNF-α.

Journal: Clinical hemorheology and microcirculation 20110101

Title: Atherogenic ω-6 Lipids Modulate PPAR- EGR-1 Crosstalk in Vascular Cells.

Journal: PPAR research 20110101

Title: Novel Danshen methoxybenzo[b]furan derivative antagonizing adipogenic differentiation and production of inflammatory adipokines.

Journal: Chemico-biological interactions 20101205

Title: hCG-induced down-regulation of PPARγ and liver X receptors promotes periovulatory progesterone synthesis by macaque granulosa cells.

Journal: Endocrinology 20101201

Title: N,N-Bis-(8-hydroxyquinoline-5-yl methyl)-benzyl substituted amines (HQNBA): peroxisome proliferator-activated receptor (PPAR-γ) agonists with neuroprotective properties.

Journal: Bioorganic & medicinal chemistry letters 20101201

Title: Regulation of liver fatty acid binding protein expression by clofibrate in hepatoma cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20101201

Title: Oleanolic acid reduces markers of differentiation in 3T3-L1 adipocytes.

Journal: Nutrition research (New York, N.Y.) 20101201

Title: Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.

Journal: Glia 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: PPAR activation has dichotomous control on the expression levels of cytosolic and secretory phospholipase A2 in astrocytes; inhibition in naïve, untreated cells and enhancement in LPS-stimulated cells.

Journal: Journal of neurochemistry 20101001

Title: Telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia.

Journal: Brain research 20100924

Title: Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARgamma activation.

Journal: Experimental dermatology 20100901

Title: White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-{gamma} and 15-lipoxygenases.

Journal: Cancer prevention research (Philadelphia, Pa.) 20100901

Title: Evidence of the involvement of K+ channels and PPARgamma receptors in the antidepressant-like activity of diphenyl diselenide in mice.

Journal: The Journal of pharmacy and pharmacology 20100901

Title: Nifedipine activates PPARgamma and exerts antioxidative action through Cu/ZnSOD independent of blood-pressure lowering in SHRSP.

Journal: Journal of atherosclerosis and thrombosis 20100831

Title: Rosiglitazone inhibits monocyte/macrophage adhesion through de novo adiponectin production in human monocytes.

Journal: Journal of cellular biochemistry 20100815

Title: Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury.

Journal: Cardiovascular research 20100801

Title: Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice.

Journal: Journal of hypertension 20100801

Title: Role of PPAR gamma/nitric oxide synthase signaling in the cyclosporine-induced attenuation of endothelium-dependent renovascular vasodilation.

Journal: Journal of cardiovascular pharmacology 20100801

Title: Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-gamma activation in mice with chronic cerebral hypoperfusion.

Journal: Stroke 20100801

Title: Nifedipine inhibits advanced glycation end products (AGEs) and their receptor (RAGE) interaction-mediated proximal tubular cell injury via peroxisome proliferator-activated receptor-gamma activation.

Journal: Biochemical and biophysical research communications 20100723

Title: 8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.

Journal: World journal of gastroenterology 20100721

Title: Mycobacterium tuberculosis activates human macrophage peroxisome proliferator-activated receptor gamma linking mannose receptor recognition to regulation of immune responses.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20100715

Title: 15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells.

Journal: Shock (Augusta, Ga.) 20100701

Title: Peroxisome proliferator-activated receptor gamma activation inhibits progesterone-stimulated human MUC1 expression.

Journal: Molecular endocrinology (Baltimore, Md.) 20100701

Title: Peroxisome proliferator-activated receptor gamma promotes neuroprotection by modulating cyclin D1 expression after focal cerebral ischemia.

Journal: Canadian journal of physiology and pharmacology 20100701

Title: Thiazolidinediones inhibit TNF-alpha-mediated osteoclast differentiation of RAW264.7 macrophages and mouse bone marrow cells through downregulation of NFATc1.

Journal: Shock (Augusta, Ga.) 20100601

Title: PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.

Journal: Cardiovascular research 20100501

Title: Thiazolidinediones as potent inducers of hepatocyte growth factor.

Journal: Hepatology (Baltimore, Md.) 20100501

Title: Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation.

Journal: International journal of molecular medicine 20100501

Title: Peroxisome proliferator-activated receptor-gamma (PPARgamma) modulates hypothalamic Trh regulation in vivo.

Journal: Molecular and cellular endocrinology 20100412

Title: 15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state.

Journal: Molecular pharmacology 20100401

Title: Peroxisome proliferator-activated receptor gamma agonist rosiglitazone attenuates oxyhemoglobin-induced Toll-like receptor 4 expression in vascular smooth muscle cells.

Journal: Brain research 20100331

Title: Selective effects of PPARgamma agonists and antagonists on human pre-adipocyte differentiation.

Journal: Diabetes, obesity & metabolism 20100301

Title: The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells.

Journal: Molecular carcinogenesis 20100301

Title: Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Journal: Journal of thrombosis and haemostasis : JTH 20100301

Title: Relaxin signaling activates peroxisome proliferator-activated receptor gamma.

Journal: Molecular and cellular endocrinology 20100205

Title: A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.

Journal: Molecular pharmacology 20100201

Title: Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema.

Journal: Neuropharmacology 20100201

Title: Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20100201

Title: Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells.

Journal: Journal of neuroimmunology 20100125

Title: A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

Title: 12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion.

Journal: Brain research 20100111

Title: The novel function of nesfatin-1: anti-hyperglycemia.

Journal: Biochemical and biophysical research communications 20100101

Title: PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia.

Journal: Brain research 20091211

Title: Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.

Journal: Atherosclerosis 20091201

Title: Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel.

Journal: Molecular pharmacology 20091201

Title: Berberine improves free-fatty-acid-induced insulin resistance in L6 myotubes through inhibiting peroxisome proliferator-activated receptor gamma and fatty acid transferase expressions.

Journal: Metabolism: clinical and experimental 20091201

Title: Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.

Journal: Physiological genomics 20091201

Title: Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism.

Journal: Endocrinology 20091201

Title: Eicosapentaenoic acid increases cytochrome P-450 2J2 gene expression and epoxyeicosatrienoic acid production via peroxisome proliferator-activated receptor γ in endothelial cells.

Journal: Journal of cardiology 20091201

Title: Selective prostacyclin receptor agonism augments glucocorticoid-induced gene expression in human bronchial epithelial cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115

Title: Role of peroxisome proliferator-activated receptor beta/delta in chicken adipogenesis.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20091101

Title: Peroxisome proliferator-activated receptor gamma activation alleviates postoperative ileus in mice by inhibition of Egr-1 expression and its downstream target genes.

Journal: The Journal of pharmacology and experimental therapeutics 20091101

Title: The PPAR-gamma agonist rosiglitazone facilitates Akt rephosphorylation and inhibits apoptosis in cardiomyocytes during hypoxia/reoxygenation.

Journal: Diabetes, obesity & metabolism 20091101

Title: Activation of peroxisome proliferator-activated receptor-gamma induces apoptosis on acute promyelocytic leukemia cells via downregulation of XIAP.

Journal: International journal of molecular medicine 20091101

Title: Differentiation of SWO-38 glioma cells induced by CDA-2 is mediated by peroxisome proliferator-activated receptor gamma.

Journal: Journal of neuro-oncology 20091001

Title: Salacia oblonga extract increases glucose transporter 4-mediated glucose uptake in L6 rat myotubes: role of mangiferin.

Journal: Clinical nutrition (Edinburgh, Scotland) 20091001

Title: Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

Journal: Molecular & cellular proteomics : MCP 20091001

Title: Cognitive deficit in amyloid-beta-injected mice was improved by pretreatment with a low dose of telmisartan partly because of peroxisome proliferator-activated receptor-gamma activation.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests.

Journal: Behavioural pharmacology 20091001

Title: Telmisartan inhibits cytokine-induced nuclear factor-kappaB activation independently of the peroxisome proliferator-activated receptor-gamma.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090901

Title: Crosstalk between peroxisome proliferator-activated receptor-gamma and angiotensin II in renal tubular epithelial cells in IgA nephropathy.

Journal: Clinical immunology (Orlando, Fla.) 20090801

Title: Nifedipine, a calcium channel blocker, inhibits advanced glycation end product (AGE)-elicited mesangial cell damage by suppressing AGE receptor (RAGE) expression via peroxisome proliferator-activated receptor-gamma activation.

Journal: Biochemical and biophysical research communications 20090724

Title: Antagonist of peroxisome proliferator-activated receptor gamma induces cerebellar amyloid-beta levels and motor dysfunction in APP/PS1 transgenic mice.

Journal: Biochemical and biophysical research communications 20090703

Title: Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail.

Journal: The Journal of nutritional biochemistry 20090701

Title: Rosiglitazone and PPAR-gamma overexpression protect mitochondrial membrane potential and prevent apoptosis by upregulating anti-apoptotic Bcl-2 family proteins.

Journal: Journal of cellular physiology 20090701

Title: Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells.

Journal: Journal of neuropathology and experimental neurology 20090701

Title: Time-dependent vascular actions of cannabidiol in the rat aorta.

Journal: European journal of pharmacology 20090610

Title: Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor.

Journal: American journal of physiology. Lung cellular and molecular physiology 20090601

Title: Repressive effect of the phytoestrogen genistein on estradiol-induced uterine leiomyoma cell proliferation.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090601

Title: Peroxisome-proliferator receptor gamma represses hepatic sex hormone-binding globulin expression.

Journal: Endocrinology 20090501

Title: A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT.

Journal: American journal of physiology. Cell physiology 20090501

Title: Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.

Journal: American journal of physiology. Heart and circulatory physiology 20090501

Title: Inhibition of tumor necrosis factor-alpha-induced interleukin-6 expression by telmisartan through cross-talk of peroxisome proliferator-activated receptor-gamma with nuclear factor kappaB and CCAAT/enhancer-binding protein-beta.

Journal: Hypertension (Dallas, Tex. : 1979) 20090501

Title: [Role of peroxisome proliferators-activated receptor-gamma in the chemical prevention therapy of sulindac for precancerous lesions of rats].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20090418

Title: Effects of benzbromarone and allopurinol on adiponectin in vivo and in vitro.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090401

Title: Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma.

Journal: Biochimie 20090401

Title: Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2.

Journal: Journal of neurochemistry 20090401

Title: Anti-inflammatory effect of peroxisome proliferator activated receptor gamma on human dental pulp cells.

Journal: Journal of endodontics 20090401

Title: Relaxin family peptide receptor 1 activation stimulates peroxisome proliferator-activated receptor gamma.

Journal: Annals of the New York Academy of Sciences 20090401

Title: Telmisartan increases the permeability of endothelial cells through zonula occludens-1.

Journal: Biological & pharmaceutical bulletin 20090301

Title: Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.

Journal: World journal of gastroenterology 20090121

Title: Rosiglitazone inhibits alpha4 nicotinic acetylcholine receptor expression in human lung carcinoma cells through peroxisome proliferator-activated receptor gamma-independent signals.

Journal: Molecular cancer therapeutics 20090101

Title: Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.

Journal: Cardiovascular diabetology 20090101

Title: Niacin promotes cholesterol efflux through stimulation of the PPARgamma-LXRalpha-ABCA1 pathway in 3T3-L1 adipocytes.

Journal: Pharmacology 20090101

Title: Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.

Journal: PloS one 20090101

Title: Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms.

Journal: Brain research 20081209

Title: Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.

Journal: European journal of medicinal chemistry 20081201

Title: Cilostazol increases 3T3-L1 preadipocyte differentiation with improved glucose uptake associated with activation of peroxisome proliferator-activated receptor-gamma transcription.

Journal: Atherosclerosis 20081201

Title: Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway.

Journal: Chinese medical journal 20081120

Title: Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}.

Journal: Blood 20081115

Title: Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression.

Journal: Oncology reports 20081101

Title: Mechanisms underlying pioglitazone-mediated relaxation in isolated blood vessel.

Journal: Journal of pharmacological sciences 20081101

Title: Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury.

Journal: Journal of pharmacological sciences 20081101

Title: Telmisartan prevented cognitive decline partly due to PPAR-gamma activation.

Journal: Biochemical and biophysical research communications 20081024

Title: Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats.

Journal: Immunology 20081001

Title: Biomolecular characterization of human glioblastoma cells in primary cultures: differentiating and antiangiogenic effects of natural and synthetic PPARgamma agonists.

Journal: Journal of cellular physiology 20081001

Title: Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages.

Journal: Biochimica et biophysica acta 20081001

Title: Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2.

Journal: Cancer letters 20080918

Title: Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease.

Journal: The Journal of biological chemistry 20080912

Title: Repression of interferon-gamma expression in T cells by Prospero-related homeobox protein.

Journal: Cell research 20080901

Title: 6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications 20080829

Title: Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol.

Journal: Toxicology and applied pharmacology 20080815

Title: Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.

Journal: Cancer investigation 20080801

Title: Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: implication of ERK1/2 and PPARgamma receptors.

Journal: Experimental neurology 20080701

Title: [Effects of activated PPARgamma on the expression of PTEN gene in pancreatic cancer cells].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20080701

Title: [Effects of peroxisome proliferators-activated receptor-gamma on the function of the vital organs in rats with pancreatitis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080601

Title: Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway.

Journal: Endocrine 20080601

Title: CITED2 signals through peroxisome proliferator-activated receptor-gamma to regulate death of cortical neurons after DNA damage.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521

Title: Peroxisome proliferator activated receptor gamma is not necessary for the development of LPS-induced tolerance in macrophages.

Journal: Immunology 20080501

Title: Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid.

Journal: Rheumatology international 20080501

Title: Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma.

Journal: The Prostate 20080501

Title: Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator-activated receptor-gamma-modulating activity, on nitric oxide bioavailability and atherosclerotic change.

Journal: Journal of hypertension 20080501

Title: Effect of troglitazone on CYP1A1 induction.

Journal: Toxicology 20080418

Title: Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts.

Journal: British journal of pharmacology 20080401

Title: [Pioglitazone inhibits dendritic cell adhesion and transmigration through down-regulation of dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin].

Journal: Zhonghua yi xue za zhi 20080325

Title: Rosiglitazone stimulates the release and synthesis of insulin by enhancing GLUT-2, glucokinase and BETA2/NeuroD expression.

Journal: Biochemical and biophysical research communications 20080314

Title: Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.

Journal: Hypertension (Dallas, Tex. : 1979) 20080301

Title: PPARgamma-dependent and -independent effects of rosiglitazone on lipotoxic human pancreatic islets.

Journal: Biochemical and biophysical research communications 20080222

Title: The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells.

Journal: Journal of neuroscience research 20080215

Title: Pigment epithelium-derived factor induces THP-1 macrophage apoptosis and necrosis by the induction of the peroxisome proliferator-activated receptor gamma.

Journal: Molecular immunology 20080201

Title: 15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20080101

Title: Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3.

Journal: BMC cancer 20080101

Title: The PPARgamma agonist FMOC-L-leucine protects both mature and immature brain.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101

Title: Eicosapentaenoic acid inhibits interleukin-6 production in interleukin-1beta-stimulated C6 glioma cells through peroxisome proliferator-activated receptor-gamma.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101

Title: PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.

Journal: PPAR research 20080101

Title: Role of PPAR-gamma in the modulation of CD36 and FcgammaRII induced by LDL with low and high degrees of oxidation during the differentiation of the monocytic THP-1 cell line.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.

Journal: American journal of physiology. Endocrinology and metabolism 20071201

Title: Peroxisome proliferator-activated receptor gamma agonist action of 3-methyl-1,2-cyclopentanedione.

Journal: Biochimica et biophysica acta 20071201

Title: Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt.

Journal: Shock (Augusta, Ga.) 20071101

Title: Peroxisome proliferator-activated receptor-gamma is involved in the control of renin gene expression.

Journal: Hypertension (Dallas, Tex. : 1979) 20071101

Title: beta-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells.

Journal: European journal of cancer (Oxford, England : 1990) 20071101

Title: Comparison of vascular relaxation, lipolysis and glucose uptake by peroxisome proliferator-activated receptor-gamma activation in +db/+m and +db/+db mice.

Journal: European journal of pharmacology 20071015

Title: Differential ability of a thiazolidinedione PPARgamma agonist to attenuate cytokine secretion in primary microglia and macrophage-like cells.

Journal: Journal of neurochemistry 20071001

Title: A peroxisome proliferator-activated receptor gamma antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma.

Journal: Oncology reports 20071001

Title: Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells.

Journal: Cytokine 20070901

Title: Induction of apoptosis of human gastric carcinoma SGC-7901 cell line by 5, 7-dihydroxy-8-nitrochrysin in vitro.

Journal: World journal of gastroenterology 20070728

Title: Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology.

Journal: ACS chemical biology 20070720

Title: Synthesis, antimicrobial, and QSAR studies of substituted benzamides.

Journal: Bioorganic & medicinal chemistry 20070615

Title: Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Journal: European journal of pharmacology 20070601

Title: Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase.

Journal: Molecular pharmacology 20070601

Title: Peroxisome proliferator-activated receptor-gamma antagonists exhibit potent antiproliferative effects versus many hematopoietic and epithelial cancer cell lines.

Journal: Anti-cancer drugs 20070601

Title: IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.

Journal: European journal of immunology 20070601

Title: Does the inhibition of c-myc expression mediate the anti-tumor activity of PPAR's ligands in prostate cancer cell lines?

Journal: Archives of biochemistry and biophysics 20070601

Title: Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells.

Journal: Acta pharmacologica Sinica 20070601

Title: 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070515

Title: Role of mitogen-activated protein kinase (MAPK) in troglitazone-induced osteoblastic cell death.

Journal: Toxicology 20070505

Title: Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells.

Journal: Chinese medical journal 20070505

Title: Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells.

Journal: International journal of cardiology 20070502

Title: Peroxisome proliferator-activated receptor gamma activation relieves expression of behavioral sensitization to methamphetamine in mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501

Title: PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.

Journal: European journal of immunology 20070501

Title: Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation.

Journal: American journal of physiology. Renal physiology 20070401

Title: PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPARgamma-dependent pathway.

Journal: Cell research 20070401

Title: Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents.

Journal: Journal of neurochemistry 20070401

Title: Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor gamma.

Journal: World journal of gastroenterology 20070314

Title: Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats.

Journal: The Journal of pharmacology and experimental therapeutics 20070301

Title: Upregulation of tumor necrosis factor-alpha expression by trans10-cis12 conjugated linoleic acid enhances phagocytosis of RAW macrophages via a peroxisome proliferator-activated receptor gamma-dependent pathway.

Journal: Cytokine 20070301

Title: [Effect of peroxisome proliferators-activated receptor-gamma in the mechanisms of sulindac against large intestine carcinoma].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20070218

Title: Resveratrol inhibits macrophage expression of EMMPRIN by activating PPARgamma.

Journal: Vascular pharmacology 20070201

Title: 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways.

Journal: Molecular pharmacology 20070201

Title: PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells.

Journal: International journal of cancer 20070201

Title: Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070101

Title: In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070101

Title: Potential role for peroxisome proliferator-activated receptor gamma in regulating luteal lifespan in the rat.

Journal: Reproduction (Cambridge, England) 20070101

Title: Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-gamma activation.

Journal: The Journal of international medical research 20070101

Title: Conjugated linoleic acid enhances glutathione synthesis and attenuates pathological signs in MRL/MpJ-Fas(lpr) mice.

Journal: Journal of lipid research 20061101

Title: Ceramide induces apoptosis via a peroxisome proliferator-activated receptor gamma-dependent pathway.

Journal: Apoptosis : an international journal on programmed cell death 20061101

Title: Phorbol ester potentiates the growth inhibitory effects of troglitazone via up-regulation of PPARgamma in A549 cells.

Journal: Biochemical and biophysical research communications 20061020

Title: PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells.

Journal: The Journal of experimental medicine 20061002

Title: Telmisartan downregulates angiotensin II type 1 receptor through activation of peroxisome proliferator-activated receptor gamma.

Journal: Cardiovascular research 20061001

Title: Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide.

Journal: Nuclear medicine and biology 20061001

Title: Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells.

Journal: Toxicology and applied pharmacology 20060901

Title: Pioglitazone induces apoptosis of macrophages in human adipose tissue.

Journal: Journal of lipid research 20060901

Title: Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties.

Journal: Cancer science 20060901

Title: PPARgamma-regulated tight junction development during human urothelial cytodifferentiation.

Journal: Journal of cellular physiology 20060801

Title: Rosiglitazone ameliorates cisplatin-induced renal injury in mice.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801

Title: Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.

Journal: Protein science : a publication of the Protein Society 20060801

Title: Troglitazone acutely inhibits protein synthesis in endothelial cells via a novel mechanism involving protein phosphatase 2A-dependent p70 S6 kinase inhibition.

Journal: American journal of physiology. Cell physiology 20060801

Title: Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation.

Journal: Molecular pharmacology 20060701

Title: The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma.

Journal: Critical care medicine 20060701

Title: A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage.

Journal: Annals of surgery 20060701

Title: Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice.

Journal: The Journal of allergy and clinical immunology 20060701

Title: [Resveratrol inhibits expression of EMMPRIN from macrophages].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060701

Title: Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo.

Journal: Biochemical pharmacology 20060628

Title: Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation.

Journal: Endocrinology 20060601

Title: Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, prevents hyperoxia-induced neonatal rat lung injury in vivo.

Journal: Pediatric pulmonology 20060601

Title: PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression.

Journal: Acta pharmacologica Sinica 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Differential modulation of cell cycle, apoptosis and PPARgamma2 gene expression by PPARgamma agonists ciglitazone and 9-hydroxyoctadecadienoic acid in monocytic cells.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060501

Title: Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol.

Journal: The Journal of pharmacology and experimental therapeutics 20060401

Title: Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia.

Journal: Critical care medicine 20060401

Title: Effects of rosiglitazone and metformin on pancreatic beta cell gene expression.

Journal: Diabetologia 20060401

Title: Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.

Journal: Journal of neurochemistry 20060401

Title: Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells.

Journal: Development, growth & differentiation 20060401

Title: Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms.

Journal: The Journal of biological chemistry 20060127

Title: Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells.

Journal: The Journal of investigative dermatology 20060101

Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues.

Journal: Placenta 20060101

Title: Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma.

Journal: American journal of nephrology 20060101

Title: Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

Title: Environmental chemical tributyltin augments adipocyte differentiation.

Journal: Toxicology letters 20051215

Title: Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces pulmonary inflammatory response in a rat model of endotoxemia.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20051101

Title: Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment.

Journal: European journal of pharmacology 20051017

Title: 5-Oxo-ETE analogs and the proliferation of cancer cells.

Journal: Biochimica et biophysica acta 20051001

Title: Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, reduces acute lung injury in endotoxemic rats.

Journal: Critical care medicine 20051001

Title: Peroxisome proliferator-activated receptor-gamma ligands suppress fibronectin gene expression in human lung carcinoma cells: involvement of both CRE and Sp1.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050901

Title: Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.

Journal: Journal of neurochemistry 20050901

Title: Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050901

Title: Differential responses of PPARalpha, PPARdelta, and PPARgamma reporter cell lines to selective PPAR synthetic ligands.

Journal: Analytical biochemistry 20050901

Title: The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion.

Journal: Kidney international 20050801

Title: Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma.

Journal: Surgery 20050801

Title: Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation.

Journal: European journal of pharmacology 20050711

Title: Nanomolar and micromolar effects of 15-deoxy-delta 12,14-prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors gamma and delta and nuclear factor kappa B.

Journal: Molecular pharmacology 20050701

Title: Peroxisome proliferator-activated receptor-gamma agonists suppress adrenocortical tumor cell proliferation and induce differentiation.

Journal: The Journal of clinical endocrinology and metabolism 20050701

Title: Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation.

Journal: The Journal of biological chemistry 20050603

Title: PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050601

Title: Critical role of peroxisome proliferator-activated receptor gamma on anoikis and invasion of squamous cell carcinoma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050601

Title: Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.

Journal: Molecular and cellular endocrinology 20050512

Title: The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a peroxisome proliferator-activated receptor-gamma antagonist.

Journal: The Journal of pharmacology and experimental therapeutics 20050501

Title: HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo.

Journal: Circulation 20050322

Title: [Effect of peroxisome proliferation activated receptor-gamma on neuronal cell death induced by hypoxia and ischemia in rats in vitro and in vivo].

Journal: Zhonghua yi xue za zhi 20050316

Title: Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells.

Journal: Cancer research 20050315

Title: Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.

Journal: Arthritis and rheumatism 20050301

Title: Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.

Journal: Cancer research 20050201

Title: Pituitary resistin gene expression is upregulated in vitro and in vivo by dexamethasone but is unaffected by rosiglitazone.

Journal: Neuroendocrinology 20050101

Title: Upregulation of connexin 43 by retinoids but not by non-provitamin A carotenoids requires RARs.

Journal: Nutrition and cancer 20050101

Title: A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.

Journal: Analytical biochemistry 20041215

Title: Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins.

Journal: Endocrinology 20041201

Title: GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activation.

Journal: British journal of pharmacology 20041201

Title: Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201

Title: Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism.

Journal: Journal of lipid research 20041101

Title: Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.

Journal: Molecular pharmacology 20041101

Title: Overexpression of short heterodimer partner recovers impaired glucose-stimulated insulin secretion of pancreatic beta-cells overexpressing UCP2.

Journal: The Journal of endocrinology 20041001

Title: 15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria.

Journal: European journal of pharmacology 20040913

Title: Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040901

Title: Nonsteroidal anti-inflammatory drugs potentiate 1-methyl-4-phenylpyridinium (MPP+)-induced cell death by promoting the intracellular accumulation of MPP+ in PC12 cells.

Journal: The Journal of pharmacology and experimental therapeutics 20040801

Title: The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines.

Journal: International journal of oncology 20040801

Title: Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding protein in the regulation of adipogenesis.

Journal: The Journal of biological chemistry 20040604

Title: Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.

Journal: The Journal of biological chemistry 20040521

Title: Fatty acid-mediated inhibition of IL-12 production by murine macrophages is independent of PPARgamma.

Journal: The British journal of nutrition 20040501

Title: Cardiovascular drugs inhibit MMP-9 activity from human THP-1 macrophages.

Journal: DNA and cell biology 20040501

Title: Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme.

Journal: Journal of cell science 20040415

Title: Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin.

Journal: Critical care medicine 20040301

Title: Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.

Journal: The Journal of biological chemistry 20040220

Title: Endogenous ligands of PPAR-gamma reduce the liver injury in haemorrhagic shock.

Journal: European journal of pharmacology 20040220

Title: Transcriptional inactivation of STAT3 by PPARgamma suppresses IL-6-responsive multiple myeloma cells.

Journal: Immunity 20040201

Title: PPARgamma mediates NSAIDs-induced upregulation of TFF2 expression in gastric epithelial cells.

Journal: FEBS letters 20040130

Title: Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma.

Journal: The American journal of pathology 20040101

Title: Inhibition of cell proliferation by potential peroxisome proliferator-activated receptor (PPAR) gamma agonists and antagonists.

Journal: Anticancer research 20040101

Title: Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20031101

Title: Induction of apoptosis by mono(2-ethylhexyl)phthalate (MEHP) in U937 cells.

Journal: Toxicology letters 20031015

Title: PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes.

Journal: Hypertension (Dallas, Tex. : 1979) 20031001

Title: PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001

Title: PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes.

Journal: Journal of neuroscience research 20030515

Title: The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.

Journal: Cancer research 20030115

Title: Peroxisome proliferator-activated receptor-gamma in thyroid eye disease: contraindication for thiazolidinedione use?

Journal: The Journal of clinical endocrinology and metabolism 20030101

Title: Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells.

Journal: Cellular and molecular life sciences : CMLS 20030101

Title: Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

Journal: Biochemistry 20020528

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

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Tags:22978-25-2 Molecular Formula|22978-25-2 MDL|22978-25-2 SMILES|22978-25-2 2-chloro-5-nitro-N-phenylbenzamide |Organic_Building_Blocks