[1]CanadianJournalofChemistry,1989,vol.67,p.2128-2135
[2]CanadianJournalofChemistry,1989,vol.67,p.2128-2135
[1]Rice,AllisonM.;Faig,Allison;Wolff,DavidE.;King,S.Bruce[BioorganicandMedicinalChemistryLetters,2021,vol.48]
[1]Rice,AllisonM.;Faig,Allison;Wolff,DavidE.;King,S.Bruce[BioorganicandMedicinalChemistryLetters,2021,vol.48]
Title: Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages.
Journal: Chemico-biological interactions 20171101
Title: Pharmacokinetics and Tissue Distribution of Benznidazole after Oral Administration in Mice.
Journal: Antimicrobial agents and chemotherapy 20170401
Title: Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.
Journal: Toxicology and applied pharmacology 20170115
Title: Systematic Review and Meta-analysis of the Pharmacokinetics of Benznidazole in the Treatment of Chagas Disease.
Journal: Antimicrobial agents and chemotherapy 20161201
Title: The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).
Journal: Toxicology and applied pharmacology 20160801
Title: Tolerance of benznidazole in a United States Chagas Disease clinic.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20150415
Title: Hepatotoxicity in mice of a novel anti-parasite drug candidate hydroxymethylnitrofurazone: a comparison with Benznidazole.
Journal: PLoS neglected tropical diseases 20141001
Title: Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi.
Journal: Environmental and molecular mutagenesis 20140501
Title: Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents.
Journal: European journal of medicinal chemistry 20131101
Title: Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives.
Journal: Journal of medicinal chemistry 20130926
Title: Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives.
Journal: Journal of medicinal chemistry 20130711
Title: Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines.
Journal: Journal of medicinal chemistry 20130227
Title: Nuclease activity and ultrastructural effects of new sulfonamides with anti-leishmanial and trypanocidal activities.
Journal: Parasitology international 20121201
Title: Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice.
Journal: Bioorganic & medicinal chemistry 20121101
Title: Decreased intensity of inflammation in benznidazole-treated mice inoculated with Trypanosoma cruzi I stocks from Mexico and persistence of circulating parasites.
Journal: The American journal of tropical medicine and hygiene 20121003
Title: Copper(II)-fluoroquinolone complexes with anti-Trypanosoma cruzi activity and DNA binding ability.
Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20121001
Title: Liver transplantation using Chagas-infected donors in uninfected recipients: a single-center experience without prophylactic therapy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20121001
Title: Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.
Journal: Brain, behavior, and immunity 20121001
Title: Seronegative conversion after incomplete benznidazole treatment in chronic Chagas disease.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20121001
Title: 2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.
Journal: Bioorganic & medicinal chemistry letters 20121001
Title: In vitro and in vivo studies of the trypanocidal activity of four terpenoid derivatives against Trypanosoma cruzi.
Journal: The American journal of tropical medicine and hygiene 20120905
Title: Benznidazole shortage makes chagas disease a neglected tropical disease in developed countries: data from Spain.
Journal: The American journal of tropical medicine and hygiene 20120905
Title: Taiwaniaquinoid and abietane quinone derivatives with trypanocidal activity against T. cruzi and Leishmania spp.
Journal: Parasitology international 20120901
Title: Antiparasitical chemotherapy in Chagas' disease cardiomyopathy: current evidence.
Journal: Tropical medicine & international health : TM & IH 20120901
Title: Synthesis and biological evaluation of some novel 1-indanone thiazolylhydrazone derivatives as anti-Trypanosoma cruzi agents.
Journal: European journal of medicinal chemistry 20120901
Title: Apis mellifera venom induces different cell death pathways in Trypanosoma cruzi.
Journal: Parasitology 20120901
Title: New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
Journal: Bioorganic & medicinal chemistry 20120815
Title: Skin lesions, malaise, and heart failure in a renal transplant recipient.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20120801
Title: Cardiomyopathy prognosis after benznidazole treatment in chronic canine Chagas' disease.
Journal: The Journal of antimicrobial chemotherapy 20120801
Title: Chagas disease in the immunosuppressed host.
Journal: Current opinion in infectious diseases 20120801
Title: Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents.
Journal: European journal of medicinal chemistry 20120801
Title: Posttherapeutic cure criteria in Chagas' disease: conventional serology followed by supplementary serological, parasitological, and molecular tests.
Journal: Clinical and vaccine immunology : CVI 20120801
Title: Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population.
Journal: The Journal of infectious diseases 20120715
Title: [A clinical and epidemiological study of the Trypanosoma cruzi infected population in the north metropolitan area of Barcelona].
Journal: Revista clinica espanola 20120701
Title: Reactivation of Chagas' disease: cutaneous manifestations in two immunosuppressed patients.
Journal: International journal of dermatology 20120701
Title: Novel 3-nitro-1H-1,2,4-triazole-based amides and sulfonamides as potential antitrypanosomal agents.
Journal: Journal of medicinal chemistry 20120614
Title: On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
Journal: European journal of medicinal chemistry 20120601
Title: American trypanosomiasis (Chagas disease).
Journal: Infectious disease clinics of North America 20120601
Title: The level of ascorbate peroxidase is enhanced in benznidazole-resistant populations of Trypanosoma cruzi and its expression is modulated by stress generated by hydrogen peroxide.
Journal: Memorias do Instituto Oswaldo Cruz 20120601
Title: Antiprotozoal sesquiterpene pyridine alkaloids from Maytenus ilicifolia.
Journal: Journal of natural products 20120525
Title: In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: their action on acute and chronic phases of Chagas disease.
Journal: Journal of medicinal chemistry 20120510
Title: Analogues of fenarimol are potent inhibitors of Trypanosoma cruzi and are efficacious in a murine model of Chagas disease.
Journal: Journal of medicinal chemistry 20120510
Title: Safety of benznidazole use in the treatment of chronic Chagas' disease.
Journal: The Journal of antimicrobial chemotherapy 20120501
Title: In vitro activity of N-benzenesulfonylbenzotriazole on Trypanosoma cruzi epimastigote and trypomastigote forms.
Journal: Experimental parasitology 20120501
Title: Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.
Journal: PLoS neglected tropical diseases 20120501
Title: Chagas disease: 'the new HIV/AIDS of the Americas'.
Journal: PLoS neglected tropical diseases 20120501
Title: Genetic characterization of Trypanosoma cruzi DTUs in wild Triatoma infestans from Bolivia: predominance of TcI.
Journal: PLoS neglected tropical diseases 20120501
Title: Identification of benzoylisoquinolines as potential anti-Chagas agents.
Journal: Bioorganic & medicinal chemistry 20120415
Title: Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania.
Journal: Journal of medicinal chemistry 20120412
Title: In vitro and in vivo trypanocidal activity of some benzimidazole derivatives against two strains of Trypanosoma cruzi.
Journal: Acta tropica 20120401
Title: CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy.
Journal: PLoS pathogens 20120401
Title: Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease.
Journal: PLoS neglected tropical diseases 20120401
Title: First century of Chagas' disease: an overview on novel approaches to nifurtimox and benzonidazole delivery systems.
Journal: Journal of pharmaceutical sciences 20120301
Title: Supply chain problems for Chagas disease treatment.
Journal: The Lancet. Infectious diseases 20120301
Title: Nifurtimox chemotherapy: collateral effects in treated Trypanosoma cruzi infected patients.
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20120301
Title: [The effect of the essential oil from Aloysia triphylla britton (lemon verbena) on Trypanosoma cruzi in mice].
Journal: Revista peruana de medicina experimental y salud publica 20120301
Title: Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers.
Journal: Bioorganic & medicinal chemistry 20120215
Title: Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles.
Journal: European journal of medicinal chemistry 20120201
Title: Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae).
Journal: Parasitology research 20120101
Title: Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase.
Journal: Bioorganic & medicinal chemistry 20120101
Title: Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors.
Journal: PLoS pathogens 20120101
Title: Proteomic analysis of Trypanosoma cruzi epimastigotes subjected to heat shock.
Journal: Journal of biomedicine & biotechnology 20120101
Title: In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infection.
Journal: PloS one 20120101
Title: Dynamics of Lymphocyte Populations during Trypanosoma cruzi Infection: From Thymocyte Depletion to Differential Cell Expansion/Contraction in Peripheral Lymphoid Organs.
Journal: Journal of tropical medicine 20120101
Title: The treatment of glioblastoma multiforme through activation of microglia and TRAIL induced by rAAV2-mediated IL-12 in a syngeneic rat model.
Journal: Journal of biomedical science 20120101
Title: Therapy of chagas disease: implications for levels of prevention.
Journal: Journal of tropical medicine 20120101
Title: Advanced megaesophagus (Group III) secondary to vector-borne Chagas disease in a 20-month-old infant.
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20120101
Title: Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease.
Journal: PloS one 20120101
Title: Leishmanicidal activity of nine novel flavonoids from Delphinium staphisagria.
Journal: TheScientificWorldJournal 20120101
Title: Molecular characterization of the hexose transporter gene in benznidazole resistant and susceptible populations of Trypanosoma cruzi.
Journal: Parasites & vectors 20120101
Title: Pyrogallol red oxidation induced by superoxide radicals: application to evaluate redox cycling of nitro compounds.
Journal: Analytical biochemistry 20111215
Title: Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents.
Journal: Bioorganic & medicinal chemistry 20111215
Title: Novel 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines as anti-chagasic agents.
Journal: Journal of medicinal chemistry 20111208
Title: Evaluation of thiosemicarbazones and semicarbazones as potential agents anti-Trypanosoma cruzi.
Journal: Experimental parasitology 20111201
Title: Knockout of the dhfr-ts gene in Trypanosoma cruzi generates attenuated parasites able to confer protection against a virulent challenge.
Journal: PLoS neglected tropical diseases 20111201
Title: Parasitic infections in HIV infected individuals: diagnostic & therapeutic challenges.
Journal: The Indian journal of medical research 20111201
Title: Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).
Journal: Bioorganic & medicinal chemistry letters 20111101
Title: Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazole as potential antibacterial, anti-Trypanosoma cruzi and antifungal agents.
Journal: Bioorganic & medicinal chemistry 20111101
Title: In vitro antiprotozoal activity of extracts of five Turkish Lamiaceae species.
Journal: Natural product communications 20111101
Title: Update in treatment of Chagas disease.
Journal: Current opinion in infectious diseases 20111001
Title: Hypercoagulability biomarkers in Trypanosoma cruzi -infected patients.
Journal: Thrombosis and haemostasis 20111001
Title: Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Congenital Chagas disease: recommendations for diagnosis, treatment and control of newborns, siblings and pregnant women.
Journal: PLoS neglected tropical diseases 20111001
Title: Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum.
Journal: Journal of natural products 20110923
Title: The current screening programme for congenital transmission of Chagas disease in Catalonia, Spain.
Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20110922
Title: [Human immunodeficiency virus and Chagas disease coinfection treated successfully with benznidazole and a raltegravir-based antiretroviral regimen: a case report].
Journal: Medicina clinica 20110910
Title: Synthesis, trypanocidal activity and molecular modeling studies of 2-alkylaminomethylquinoline derivatives.
Journal: European journal of medicinal chemistry 20110901
Title: The Trypanosoma cruzi protease cruzain mediates immune evasion.
Journal: PLoS pathogens 20110901
Title: Impact of aetiological treatment on conventional and multiplex serology in chronic Chagas disease.
Journal: PLoS neglected tropical diseases 20110901
Title: Retracing micro-epidemics of Chagas disease using epicenter regression.
Journal: PLoS computational biology 20110901
Title: Side effects of benznidazole treatment in a cohort of patients with Chagas disease in non-endemic country.
Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20110901
Title: Chronic phase of Chagas disease: why should it be treated? A comprehensive review.
Journal: Memorias do Instituto Oswaldo Cruz 20110901
Title: Trypanosoma cruzi: evaluation of (-)-cubebin derivatives activity in the messenger RNAs processing.
Journal: Parasitology research 20110801
Title: Immunomodulatory and anti-fibrotic effects of ganglioside therapy on the cardiac chronic form of experimental Trypanosoma cruzi infection.
Journal: International immunopharmacology 20110801
Title: Benznidazole microcrystal preparation by solvent change precipitation and in vivo evaluation in the treatment of Chagas disease.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801
Title: The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing.
Journal: PLoS neglected tropical diseases 20110801
Title: Real-time PCR in HIV/Trypanosoma cruzi coinfection with and without Chagas disease reactivation: association with HIV viral load and CD4 level.
Journal: PLoS neglected tropical diseases 20110801
Title: Activity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screening.
Journal: PLoS neglected tropical diseases 20110801
Title: The use of IgG antibodies in conventional and non-conventional immunodiagnostic tests for early prognosis after treatment of Chagas disease.
Journal: Journal of immunological methods 20110729
Title: Chagas disease in Latin American migrants: a Spanish challenge.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20110701
Title: Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues.
Journal: European journal of medicinal chemistry 20110701
Title: Antitrypanosomal therapy for chronic Chagas' disease.
Journal: The New England journal of medicine 20110630
Title: In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi.
Journal: The Journal of antimicrobial chemotherapy 20110601
Title: The use of solid dispersion systems in hydrophilic carriers to increase benzonidazole solubility.
Journal: Journal of pharmaceutical sciences 20110601
Title: In vitro and in vivo antiparasital activity against Trypanosoma cruzi of three novel 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one-based complexes.
Journal: Journal of inorganic biochemistry 20110601
Title: Neuronal changes caused by Trypanosoma cruzi: an experimental model.
Journal: Anais da Academia Brasileira de Ciencias 20110601
Title: Parasitic loads in tissues of mice infected with Trypanosoma cruzi and treated with AmBisome.
Journal: PLoS neglected tropical diseases 20110601
Title: I Latin American Guidelines for the diagnosis and treatment of Chagas' heart disease: executive summary.
Journal: Arquivos brasileiros de cardiologia 20110601
Title: Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity.
Journal: Bioorganic & medicinal chemistry letters 20110515
Title: Target validation: linking target and chemical properties to desired product profile.
Journal: Current topics in medicinal chemistry 20110501
Title: Mining a cathepsin inhibitor library for new antiparasitic drug leads.
Journal: PLoS neglected tropical diseases 20110501
Title: Current status of Chagas disease chemotherapy.
Journal: Expert review of anti-infective therapy 20110501
Title: Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp.
Journal: Journal of natural products 20110425
Title: In vitro and in vivo trypanocidal activity of flavonoids from Delphinium staphisagria against Chagas disease.
Journal: Journal of natural products 20110425
Title: Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.
Journal: The Journal of biological chemistry 20110415
Title: Humoral immune response against P2β from Trypanosoma cruzi in persons with chronic Chagas disease: its relationship with treatment against parasites and myocardial damage.
Journal: The American journal of tropical medicine and hygiene 20110405
Title: Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain.
Journal: PLoS neglected tropical diseases 20110401
Title: Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6.
Journal: Molecular and biochemical parasitology 20110301
Title: Benznidazole treatment attenuates liver NF-κB activity and MAPK in a cecal ligation and puncture model of sepsis.
Journal: Molecular immunology 20110301
Title: Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi.
Journal: PLoS neglected tropical diseases 20110301
Title: In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.
Journal: Journal of medicinal chemistry 20110224
Title: Zanthoxylum chiloperone leaves extract: first sustainable Chagas disease treatment.
Journal: Journal of ethnopharmacology 20110216
Title: A Latin American man with palpitations, dizziness, episodes of nonsustained ventricular tachycardia, and an apical aneurysm.
Journal: PLoS neglected tropical diseases 20110201
Title: Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion.
Journal: PLoS neglected tropical diseases 20110201
Title: [Update on the treatment of Chagas' disease].
Journal: Revista medica de Chile 20110201
Title: Brazilian Green Propolis: Effects In Vitro and In Vivo on Trypanosoma cruzi.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: A high-performance liquid chromatographic method for benznidazole quantitation in plasma of patients with Chagas disease.
Journal: Clinical chemistry and laboratory medicine 20110101
Title: Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease.
Journal: Current medicinal chemistry 20110101
Title: Structure of the inhibitor complex of old yellow enzyme from Trypanosoma cruzi.
Journal: Journal of synchrotron radiation 20110101
Title: Adverse events after the use of benznidazole in infants and children with Chagas disease.
Journal: Pediatrics 20110101
Title: [Clinical and radiological evaluation of the esophagus and colon in the acute phase of Chagas disease with Report of three cases of spontaneous remission of esophageal group I aperistalsis].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20110101
Title: [Chagas disease in Mexico. Report of two acute cases].
Journal: Gaceta medica de Mexico 20110101
Title: Mitochondrial dysfunction in Trypanosoma cruzi: the role of Serratia marcescens prodigiosin in the alternative treatment of Chagas disease.
Journal: Parasites & vectors 20110101
Title: Nutritional Status Driving Infection by Trypanosoma cruzi: Lessons from Experimental Animals.
Journal: Journal of tropical medicine 20110101
Title: Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives.
Journal: Current topics in medicinal chemistry 20110101
Title: Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection.
Journal: PloS one 20110101
Title: Screening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies.
Journal: The open medicinal chemistry journal 20110101
Title: The Involvement of Glutamate Metabolism in the Resistance to Thermal, Nutritional, and Oxidative Stress in Trypanosoma cruzi.
Journal: Enzyme research 20110101
Title: Antiprotozoal activities of organic extracts from French marine seaweeds.
Journal: Marine drugs 20110101
Title: Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies.
Journal: PloS one 20110101
Title: Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers.
Journal: BMC infectious diseases 20110101
Title: Combined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivo.
Journal: PloS one 20110101
Title: Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benzonidazole in Trypanosoma cruzi.
Journal: Parasites & vectors 20110101
Title: The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi.
Journal: Journal of parasitology research 20110101
Title: Heme-induced ROS in Trypanosoma cruzi activates CaMKII-like that triggers epimastigote proliferation. One helpful effect of ROS.
Journal: PloS one 20110101
Title: 3-Hydroxy kynurenine treatment controls T. cruzi replication and the inflammatory pathology preventing the clinical symptoms of chronic Chagas disease.
Journal: PloS one 20110101
Title: Benzonidazole therapy modulates interferon-γ and M2 muscarinic receptor autoantibody responses in Trypanosoma cruzi-infected children.
Journal: PloS one 20110101
Title: Glucose-6-phosphate dehydrogenase of trypanosomatids: characterization, target validation, and drug discovery.
Journal: Molecular biology international 20110101
Title: Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.
Journal: Molecular biology international 20110101
Title: Co-infection Trypanosoma cruzi/HIV: systematic review (1980-2010).
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20110101
Title: Synergistic effects of parthenolide and benznidazole on Trypanosoma cruzi.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20101215
Title: Heart rate variability in chronic Chagas patients before and after treatment with benznidazole.
Journal: Autonomic neuroscience : basic & clinical 20101208
Title: Effects of dehydroepiandrosterone-sulfate (DHEA-S) and benznidazole treatments during acute infection of two different Trypanosoma cruzi strains.
Journal: Immunobiology 20101201
Title: Canova medication modifies parasitological parameters in mice infected with Trypanosoma cruzi.
Journal: Experimental parasitology 20101201
Title: High antitrypanosomal activity of plant-derived sulphur-containing amides.
Journal: International journal of antimicrobial agents 20101201
Title: Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity.
Journal: European journal of medicinal chemistry 20101201
Title: [Chagas' disease as a cause of cerebral mass in a patient with lymphoblastic leukemia in remission].
Journal: Archivos argentinos de pediatria 20101201
Title: The potential economic value of a Trypanosoma cruzi (Chagas disease) vaccine in Latin America.
Journal: PLoS neglected tropical diseases 20101201
Title: Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis.
Journal: Biochemical pharmacology 20101115
Title: Tolerance and safety of nifurtimox in patients with chronic chagas disease.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101115
Title: Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Journal: Bioorganic & medicinal chemistry 20101115
Title: Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.
Journal: Bioorganic & medicinal chemistry 20101115
Title: Antioxidant therapy attenuates oxidative insult caused by benzonidazole in chronic Chagas' heart disease.
Journal: International journal of cardiology 20101105
Title: QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids.
Journal: European journal of medicinal chemistry 20101101
Title: 2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.
Journal: Bioorganic & medicinal chemistry 20101101
Title: Trypanosoma cruzi benznidazole susceptibility in vitro does not predict the therapeutic outcome of human Chagas disease.
Journal: Memorias do Instituto Oswaldo Cruz 20101101
Title: The anticancer drug tamoxifen is active against Trypanosoma cruzi in vitro but ineffective in the treatment of the acute phase of Chagas disease in mice.
Journal: Memorias do Instituto Oswaldo Cruz 20101101
Title: Chagas cardiomyopathy manifestations and Trypanosoma cruzi genotypes circulating in chronic Chagasic patients.
Journal: PLoS neglected tropical diseases 20101101
Title: Metabolization of nifurtimox and benznidazole in cellular fractions of rat mammary tissue.
Journal: Human & experimental toxicology 20101001
Title: Trypanosoma cruzi: biological characterization of a isolate from an endemic area and its susceptibility to conventional drugs.
Journal: Experimental parasitology 20101001
Title: Croton cajucara crude extract and isolated terpenes: activity on Trypanosoma cruzi.
Journal: Parasitology research 20101001
Title: Antitrypanosomal agents: treatment or threat?
Journal: Lancet (London, England) 20100904
Title: Synthesis and preliminary bioactivity assays of 3,4-dichloro-5-(omega-hydroxyalkylamino)-2(5H)-furanones.
Journal: European journal of medicinal chemistry 20100901
Title: Benznidazole blocks NF-kappaB activation but not AP-1 through inhibition of IKK.
Journal: Molecular immunology 20100901
Title: Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas.
Journal: Bioorganic & medicinal chemistry 20100901
Title: A preformulation study of a new medicine for Chagas disease treatment: physicochemical characterization, thermal stability, and compatibility of benznidazole.
Journal: AAPS PharmSciTech 20100901
Title: In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.
Journal: PLoS neglected tropical diseases 20100901
Title: Congenital infections with Trypanosoma cruzi or Toxoplasma gondii are associated with decreased serum concentrations of interferon-γ and interleukin-18 but increased concentrations of interleukin-10.
Journal: Annals of tropical medicine and parasitology 20100901
Title: Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi.
Journal: PLoS pathogens 20100901
Title: Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium.
Journal: Journal of natural products 20100827
Title: Reduction of parasitism tissue by treatment of mice chronically infected with Trypanosoma cruzi with lignano lactones.
Journal: Parasitology research 20100801
Title: Usefulness of PCR for monitoring benznidazole response in patients with chronic Chagas' disease: a prospective study in a non-disease-endemic country.
Journal: The Journal of antimicrobial chemotherapy 20100801
Title: Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease.
Journal: Redox report : communications in free radical research 20100801
Title: Chagas disease: changes in knowledge and management.
Journal: The Lancet. Infectious diseases 20100801
Title: A comparative study of posaconazole and benznidazole in the prevention of heart damage and promotion of trypanocidal immune response in a murine model of Chagas disease.
Journal: International journal of antimicrobial agents 20100701
Title: In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds.
Journal: PLoS neglected tropical diseases 20100701
Title: Chagas disease: pushing through the pipeline.
Journal: Nature 20100624
Title: Mode of action of nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: is oxidative stress involved?
Journal: Biochemical pharmacology 20100615
Title: Naftifine-analogues as anti-Trypanosoma cruzi agents.
Journal: European journal of medicinal chemistry 20100601
Title: Acute Chagas' disease in postrenal transplant and treatment with benzonidazole.
Journal: Annals of diagnostic pathology 20100601
Title: Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats.
Journal: Journal of the American College of Cardiology 20100601
Title: Clinical outcomes of thirteen patients with acute chagas disease acquired through oral transmission from two urban outbreaks in northeastern Brazil.
Journal: PLoS neglected tropical diseases 20100601
Title: The centennial of the discovery of Chagas disease: facing the current challenges.
Journal: PLoS neglected tropical diseases 20100601
Title: Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity.
Journal: British journal of pharmacology 20100501
Title: Nitric oxide donor trans-[RuCl([15]aneN)NO] as a possible therapeutic approach for Chagas' disease.
Journal: British journal of pharmacology 20100501
Title: New method for quantification of Trypanosoma cruzi in animal's tissue in the chronic phase of experimental Chagas' disease.
Journal: Parasitology research 20100501
Title: The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
Journal: Bioorganic & medicinal chemistry 20100501
Title: New drugs for neglected infectious diseases: Chagas' disease.
Journal: British journal of pharmacology 20100501
Title: Computational identification of uncharacterized cruzain binding sites.
Journal: PLoS neglected tropical diseases 20100501
Title: 'Manifesto' for advancing the control and elimination of neglected tropical diseases.
Journal: PLoS neglected tropical diseases 20100501
Title: Chagas disease.
Journal: Lancet (London, England) 20100417
Title: Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines.
Journal: Bioorganic & medicinal chemistry 20100415
Title: Successful treatment with posaconazole of a patient with chronic Chagas disease and systemic lupus erythematosus.
Journal: The American journal of tropical medicine and hygiene 20100401
Title: Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.
Journal: PLoS neglected tropical diseases 20100401
Title: Nanotechnological approaches against Chagas disease.
Journal: Advanced drug delivery reviews 20100318
Title: Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi.
Journal: Bioorganic & medicinal chemistry letters 20100315
Title: In vitro and in vivo experimental models for drug screening and development for Chagas disease.
Journal: Memorias do Instituto Oswaldo Cruz 20100301
Title: Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole.
Journal: Experimental parasitology 20100201
Title: Trypanosoma cruzi: Immunological predictors of benznidazole efficacy during experimental infection.
Journal: Experimental parasitology 20100201
Title: Benznidazole alters the pattern of Cyclophosphamide-induced reactivation in experimental Trypanosoma cruzi-dependent lineage infection.
Journal: Acta tropica 20100201
Title: Prevalence, clinical staging and risk for blood-borne transmission of Chagas disease among Latin American migrants in Geneva, Switzerland.
Journal: PLoS neglected tropical diseases 20100201
Title: [Emergence of Chagas' disease in Europe: description of the first cases observed in Latin American immigrants in mainland France].
Journal: Medecine tropicale : revue du Corps de sante colonial 20100201
Title: Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches.
Journal: Acta tropica 20100101
Title: Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines.
Journal: Bioorganic & medicinal chemistry 20100101
Title: Antibody drop in newborns congenitally infected by Trypanosoma cruzi treated with benznidazole.
Journal: Tropical medicine & international health : TM & IH 20100101
Title: Chagas disease: progress and new perspectives.
Journal: Current medicinal chemistry 20100101
Title: Inhibitory activity of marine sponge-derived natural products against parasitic protozoa.
Journal: Marine drugs 20100101
Title: Trypanosomatid parasites causing neglected diseases.
Journal: Current medicinal chemistry 20100101
Title: [Adverse reactions in Chagas disease patients treated with benznidazole, in the State of Ceará].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20100101
Title: Development of and access to products for neglected diseases.
Journal: PloS one 20100101
Title: Bromopyrrole alkaloids as lead compounds against protozoan parasites.
Journal: Marine drugs 20100101
Title: Current and emerging therapeutic options for the treatment of chronic chagasic cardiomyopathy.
Journal: Vascular health and risk management 20100101
Title: Current and developing therapeutic agents in the treatment of Chagas disease.
Journal: Drug design, development and therapy 20100101
Title: Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment.
Journal: BMC genomics 20100101
Title: Chagas disease: Present status of pathogenic mechanisms and chemotherapy.
Journal: Biological research 20100101
Title: A comparative analysis of the Libyan national essential medicines list and the WHO model list of essential medicines.
Journal: The Libyan journal of medicine 20100101
Title: New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and mechanism of action studies.
Journal: Bioorganic & medicinal chemistry 20091215
Title: Use of benznidazole to treat chronic Chagas' disease: a systematic review with a meta-analysis.
Journal: The Journal of antimicrobial chemotherapy 20091201
Title: Anti-trypanosomatid benzofuroxans and deoxygenated analogues: synthesis using polymer-supported triphenylphosphine, biological evaluation and mechanism of action studies.
Journal: European journal of medicinal chemistry 20091201
Title: Changes in Trypanosoma cruzi-specific immune responses after treatment: surrogate markers of treatment efficacy.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20091201
Title: Recognizing and meeting the challenge of Chagas disease in the USA.
Journal: Expert review of anti-infective therapy 20091201
Title: Maternal infection with Trypanosoma cruzi and congenital Chagas disease induce a trend to a type 1 polarization of infant immune responses to vaccines.
Journal: PLoS neglected tropical diseases 20091201
Title: [Chagas disease and immunodeficiency: HIV infection and transplantation].
Journal: Bulletin de la Societe de pathologie exotique (1990) 20091201
Title: Clinical and laboratory status of patients with chronic Chagas disease living in a vector-controlled area in Minas Gerais, Brazil, before and nine years after aetiological treatment.
Journal: Memorias do Instituto Oswaldo Cruz 20091201
Title: Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles.
Journal: Journal of medicinal chemistry 20091112
Title: Second generation of 2H-benzimidazole 1,3-dioxide derivatives as anti-trypanosomatid agents: synthesis, biological evaluation, and mode of action studies.
Journal: European journal of medicinal chemistry 20091101
Title: 5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene.
Journal: Bioorganic & medicinal chemistry 20091101
Title: Treatment and seroconversion in a cohort of children suffering from recent chronic Chagas infection in Yoro, Honduras.
Journal: Memorias do Instituto Oswaldo Cruz 20091101
Title: Trypanosoma cruzi: parasite antigens sequestered in heart interstitial dendritic cells are related to persisting myocarditis in benznidazole-treated mice.
Journal: Memorias do Instituto Oswaldo Cruz 20091101
Title: Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.
Journal: Bioorganic & medicinal chemistry 20091015
Title: Antiprotozoal and cytotoxic studies on some isocordoin derivatives.
Journal: Planta medica 20091001
Title: Trypanosoma cruzi: Different methods of data analysis to evaluate the genetics-biology relationship.
Journal: Experimental parasitology 20091001
Title: Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents.
Journal: Bioorganic & medicinal chemistry 20090915
Title: Molecular diagnosis and treatment monitoring of congenital transmission of Trypanosoma cruzi to twins of a triplet delivery.
Journal: Diagnostic microbiology and infectious disease 20090901
Title: Aetiological treatment with itraconazole or ketoconazole in individuals with Trypanosoma cruzi/HIV co-infection.
Journal: Annals of tropical medicine and parasitology 20090901
Title: Profile of central and effector memory T cells in the progression of chronic human chagas disease.
Journal: PLoS neglected tropical diseases 20090901
Title: In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole.
Journal: Biomedica : revista del Instituto Nacional de Salud 20090901
Title: [Chagas disease].
Journal: La Revue de medecine interne 20090801
Title: Advancing drug innovation for neglected diseases-criteria for lead progression.
Journal: PLoS neglected tropical diseases 20090801
Title: Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships.
Journal: Bioorganic & medicinal chemistry 20090715
Title: Synthesis and in vitro trichomonicidal, giardicidal and amebicidal activity of N-acetamide(sulfonamide)-2-methyl-4-nitro-1H-imidazoles.
Journal: European journal of medicinal chemistry 20090701
Title: Characterization of a gene encoding alcohol dehydrogenase in benznidazole-susceptible and -resistant populations of Trypanosoma cruzi.
Journal: Acta tropica 20090701
Title: Differential regional immune response in Chagas disease.
Journal: PLoS neglected tropical diseases 20090701
Title: Feasibility, drug safety, and effectiveness of etiological treatment programs for Chagas disease in Honduras, Guatemala, and Bolivia: 10-year experience of Médecins Sans Frontières.
Journal: PLoS neglected tropical diseases 20090701
Title: New, improved treatments for Chagas disease: from the R&D pipeline to the patients.
Journal: PLoS neglected tropical diseases 20090701
Title: Present situation and new strategies for Chagas disease chemotherapy: a proposal.
Journal: Memorias do Instituto Oswaldo Cruz 20090701
Title: Ergosterol biosynthesis and drug development for Chagas disease.
Journal: Memorias do Instituto Oswaldo Cruz 20090701
Title: The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease.
Journal: Memorias do Instituto Oswaldo Cruz 20090701
Title: Novel cytostatic activity of the trypanocidal drug Benznidazole.
Journal: International immunopharmacology 20090601
Title: Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase.
Journal: Bioorganic & medicinal chemistry letters 20090601
Title: Chagas disease: the forgotten American neuroinfection.
Journal: The Lancet. Neurology 20090601
Title: In vitro trypanocidal activity of phenolic derivatives from Peperomia obtusifolia.
Journal: Planta medica 20090501
Title: Reduction of parasite levels in blood improves pregnancy outcome during experimental Trypanosoma cruzi infection.
Journal: Parasitology 20090501
Title: Trypanosoma cruzi: antiproliferative effect of indole phytoalexins on intracellular amastigotes in vitro.
Journal: Experimental parasitology 20090501
Title: New perspectives of infections in cardiovascular disease.
Journal: Current cardiology reviews 20090501
Title: Comparative study of the trypanocidal activity of the methyl 1-nitrophenyl-1,2,3,4-9H-tetrahydro-beta-carboline-3-carboxylate derivatives and benznidazole using theoretical calculations and cyclic voltammetry.
Journal: European journal of medicinal chemistry 20090401
Title: 2,3-diphenyl-1,4-naphthoquinone: a potential chemotherapeutic agent against Trypanosoma cruzi.
Journal: The Journal of parasitology 20090401
Title: Molecular modeling studies and in vitro bioactivity evaluation of a set of novel 5-nitro-heterocyclic derivatives as anti-T. cruzi agents.
Journal: Bioorganic & medicinal chemistry 20090401
Title: A systematic review of studies on heart transplantation for patients with end-stage Chagas' heart disease.
Journal: Journal of cardiac failure 20090401
Title: Congenital transmission of Chagas disease in Latin American immigrants in Switzerland.
Journal: Emerging infectious diseases 20090401
Title: Chagasic cardiomyopathy in immigrants from Latin America to Spain.
Journal: Emerging infectious diseases 20090401
Title: Accurate real-time PCR strategy for monitoring bloodstream parasitic loads in chagas disease patients.
Journal: PLoS neglected tropical diseases 20090401
Title: In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles.
Journal: European journal of medicinal chemistry 20090301
Title: Molecular characterization of cytosolic and mitochondrial tryparedoxin peroxidase in Trypanosoma cruzi populations susceptible and resistant to benznidazole.
Journal: Parasitology research 20090301
Title: Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities.
Journal: Expert review of anti-infective therapy 20090301
Title: Influence of Ecto-nucleoside triphosphate diphosphohydrolase activity on Trypanosoma cruzi infectivity and virulence.
Journal: PLoS neglected tropical diseases 20090301
Title: Development of novel formulations for Chagas' disease: Optimization of benznidazole chitosan microparticles based on artificial neural networks.
Journal: International journal of pharmaceutics 20090209
Title: Synthesis, in vitro antitrypanosomal and antibacterial activity of phenoxy, phenylthio or benzyloxy substituted quinolones.
Journal: Bioorganic & medicinal chemistry letters 20090201
Title: Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.
Journal: PLoS neglected tropical diseases 20090201
Title: Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening.
Journal: PLoS neglected tropical diseases 20090201
Title: Antiparasitic activity of biochanin A, an isolated isoflavone from fruits of Cassia fistula (Leguminosae).
Journal: Parasitology research 20090101
Title: Trypanosoma cruzi: Genetic diversity influences the profile of immunoglobulins during experimental infection.
Journal: Experimental parasitology 20090101
Title: Absence of CD4+ T lymphocytes, CD8+ T lymphocytes, or B lymphocytes has different effects on the efficacy of posaconazole and benznidazole in treatment of experimental acute Trypanosoma cruzi infection.
Journal: Antimicrobial agents and chemotherapy 20090101
Title: Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
Title: Trypanosoma cruzi targets for new chemotherapeutic approaches.
Journal: Expert opinion on therapeutic targets 20090101
Title: Pediatric clinical pharmacology studies in Chagas disease: focus on Argentina.
Journal: Paediatric drugs 20090101
Title: Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi.
Journal: PloS one 20090101
Title: Urban outbreak of acute Chagas disease in Amazon region of Brazil: four-year follow-up after treatment with benznidazole.
Journal: Revista panamericana de salud publica = Pan American journal of public health 20090101
Title: Copper (II) complexes of [1,2,4]triazolo [1,5-a]pyrimidine derivatives as potential anti-parasitic agents.
Journal: Drug metabolism letters 20090101
Title: GPIomics: global analysis of glycosylphosphatidylinositol-anchored molecules of Trypanosoma cruzi.
Journal: Molecular systems biology 20090101
Title: Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi.
Journal: BMC microbiology 20090101
Title: Proteomic and network analysis characterize stage-specific metabolism in Trypanosoma cruzi.
Journal: BMC systems biology 20090101
Title: [Fatal evolution of Chagas'disease/Aids co-infection: diagnostic difficulties between myocarditis reactivation and chronic chagasic myocardiopathy].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20090101
Title: Experimental evaluation of insecticidal paints against Triatoma infestans (Hemiptera: Reduviidae), under natural climatic conditions.
Journal: Parasites & vectors 20090101
Title: Accidental infection by Trypanosoma cruzi follow-up by the polymerase chain reaction: case report.
Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20090101
Title: Etiological treatment of young women infected with Trypanosoma cruzi, and prevention of congenital transmission.
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20090101
Title: Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.
Journal: Journal of parasitology research 20090101
Title: Trypanosoma cruzi: effect of benznidazole therapy combined with the iron chelator desferrioxamine in infected mice.
Journal: Experimental parasitology 20081201
Title: Trypanosoma cruzi: Induction of benznidazole resistance in vivo and its modulation by in vitro culturing and mice infection.
Journal: Experimental parasitology 20081201
Title: Reactivation of Chagas disease with central nervous system involvement in HIV-infected patients in Argentina, 1992-2007.
Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20081101
Title: Beneficial effects of benznidazole during an infectious-based situation of systemic inflammatory response: cecal ligation and puncture.
Journal: The American journal of tropical medicine and hygiene 20081101
Title: Anti-T. cruzi agents: our experience in the evaluation of more than five hundred compounds.
Journal: Mini reviews in medicinal chemistry 20081101
Title: In vivo studies of 5-arylethenylbenzofuroxans in acute murine models of Chagas' disease.
Journal: European journal of medicinal chemistry 20081001
Title: Chagas disease and the US blood supply.
Journal: Current opinion in infectious diseases 20081001
Title: Benznidazole and Chagas disease: can an old drug be the answer to an old problem?
Journal: Expert opinion on investigational drugs 20081001
Title: High throughput selection of effective serodiagnostics for Trypanosoma cruzi infection.
Journal: PLoS neglected tropical diseases 20081001
Title: [Part VI. Antiparasitic treatment for Chagas disease].
Journal: Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20081001
Title: Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: in silico, in vitro and in vivo activity studies.
Journal: European journal of medicinal chemistry 20080901
Title: Usefulness of the polymerase chain reaction for monitoring cure of mice infected with different Trypanosoma cruzi clonal genotypes following treatment with benznidazole.
Journal: Experimental parasitology 20080901
Title: Furoxan-, alkylnitrate-derivatives and related compounds as anti-trypanosomatid agents: mechanism of action studies.
Journal: Bioorganic & medicinal chemistry 20080901
Title: Benzoic acid derivatives from Piper species and their antiparasitic activity.
Journal: Journal of natural products 20080901
Title: Brazilian propolis: correlation between chemical composition and antimicrobial activity.
Journal: Evidence-based complementary and alternative medicine : eCAM 20080901
Title: Benznidazole biotransformation in rat heart microsomal fraction without observable ultrastructural alterations: comparison to Nifurtimox-induced cardiac effects.
Journal: Memorias do Instituto Oswaldo Cruz 20080901
Title: Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
Journal: European journal of medicinal chemistry 20080801
Title: Pyrimido[1,2-a]quinoxaline 6-oxide and phenazine 5,10-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi.
Journal: European journal of medicinal chemistry 20080801
Title: Complexation of the anti-Trypanosoma cruzi drug benznidazole improves solubility and efficacy.
Journal: Journal of medicinal chemistry 20080724
Title: New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle.
Journal: Bioorganic & medicinal chemistry 20080715
Title: Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions.
Journal: Parasitology research 20080701
Title: Multiple NADPH-cytochrome P450 reductases from Trypanosoma cruzi suggested role on drug resistance.
Journal: Molecular and biochemical parasitology 20080701
Title: Differential gene expression in Trypanosoma cruzi populations susceptible and resistant to benznidazole.
Journal: Acta tropica 20080701
Title: Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT).
Journal: American heart journal 20080701
Title: Persistence of PCR-positive tissue in benznidazole-treated mice with negative blood parasitological and serological tests in dual infections with Trypanosoma cruzi stocks from different genotypes.
Journal: The Journal of antimicrobial chemotherapy 20080601
Title: Proteomic analysis of Trypanosoma cruzi resistance to Benznidazole.
Journal: Journal of proteome research 20080601
Title: 4-nitroacetophenone-derived thiosemicarbazones and their copper(II) complexes with significant in vitro anti-trypanosomal activity.
Journal: European journal of medicinal chemistry 20080501
Title: Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.
Journal: Bioorganic & medicinal chemistry 20080501
Title: Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease.
Journal: Nature medicine 20080501
Title: Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity.
Journal: Bioorganic & medicinal chemistry letters 20080401
Title: Chagas disease, France.
Journal: Emerging infectious diseases 20080401
Title: Changes of RAPD profile of Trypanosoma cruzi II with Canova and Benznidazole.
Journal: Homeopathy : the journal of the Faculty of Homeopathy 20080401
Title: Acute chagasic myocardiopathy after orthotopic liver transplantation with donor and recipient serologically negative for Trypanosoma cruzi: a case report.
Journal: Transplantation proceedings 20080401
Title: Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings.
Journal: Journal of medicinal chemistry 20080327
Title: Trypanosoma cruzi: acute and long-term infection in the vertebrate host can modify the response to benznidazole.
Journal: Experimental parasitology 20080301
Title: Natural chromenes and chromene derivatives as potential anti-trypanosomal agents.
Journal: Biological & pharmaceutical bulletin 20080301
Title: Voltammetric Behavior of o-Nitrophenol and Damage to DNA.
Journal: International journal of molecular sciences 20080301
Title: Benznidazole.
Journal: Acta crystallographica. Section E, Structure reports online 20080301
Title: Severe invalidating pain syndrome associated with benznidazole therapy for Chagas' disease.
Journal: Clinical rheumatology 20080201
Title: Etiological treatment during early chronic indeterminate Chagas disease incites an activated status on innate and adaptive immunity associated with a type 1-modulated cytokine pattern.
Journal: Microbes and infection 20080201
Title: Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
Journal: Bioorganic & medicinal chemistry 20080115
Title: Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids.
Journal: European journal of medicinal chemistry 20080101
Title: Trypanosoma cruzi: characterisation of the gene encoding tyrosine aminotransferase in benznidazole-resistant and susceptible populations.
Journal: Experimental parasitology 20080101
Title: Leishmanicidal and trypanocidal activities of 2-aminocyclohexanol and 1,2-cyclohexanediamine derivatives.
Journal: Bioorganic & medicinal chemistry letters 20080101
Title: Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections.
Journal: Advances in experimental medicine and biology 20080101
Title: Trypanosomiasis vector control in Africa and Latin America.
Journal: Parasites & vectors 20080101
Title: Trypanosoma cruzi alkaline 2-DE: Optimization and application to comparative proteome analysis of flagellate life stages.
Journal: Proteome science 20080101
Title: In vitro activity of compounds isolated from Piper crassinervium against Trypanosoma cruzi.
Journal: Natural product research 20080101
Title: Silencing cytokeratin 18 gene inhibits intracellular replication of Trypanosoma cruzi in HeLa cells but not binding and invasion of trypanosomes.
Journal: BMC cell biology 20080101
Title: Synthesis and in vitro evaluation of leishmanicidal and trypanocidal activities of N-quinolin-8-yl-arylsulfonamides.
Journal: Bioorganic & medicinal chemistry 20071215
Title: Targeted screening strategies to detect Trypanosoma cruzi infection in children.
Journal: PLoS neglected tropical diseases 20071201
Title: Combining residual insecticide spraying campaigns with targeted detection and specific chemotherapy for Trypanosoma cruzi infection in children.
Journal: PLoS neglected tropical diseases 20071201
Title: The challenges of Chagas Disease-- grim outlook or glimmer of hope.
Journal: PLoS medicine 20071201
Title: In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives.
Journal: Journal of medicinal chemistry 20071129
Title: Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives.
Journal: Journal of medicinal chemistry 20071115
Title: Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli.
Journal: Bioorganic & medicinal chemistry 20071101
Title: An overview of Chagas disease treatment.
Journal: Memorias do Instituto Oswaldo Cruz 20071030
Title: Allopurinol is effective to modify the evolution of Trypanosoma cruzi infection in mice.
Journal: Parasitology research 20071001
Title: Early nifurtimox-induced biochemical and ultrastructural alterations in rat heart.
Journal: Human & experimental toxicology 20071001
Title: Synthesis, Cruzain docking, and in vitro studies of aryl-4-oxothiazolylhydrazones against Trypanosoma cruzi.
Journal: ChemMedChem 20070901
Title: Synthesis and in vitro protozoocidal activity of diazabicyclic benzotropolone derivatives.
Journal: Bioorganic & medicinal chemistry letters 20070801
Title: Chagas disease: clinical overview and implications for nursing.
Journal: Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20070801
Title: DNA damage and nitric oxide synthesis in experimentally infected Balb/c mice with Trypanosoma cruzi.
Journal: Experimental parasitology 20070701
Title: Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy.
Journal: International journal of antimicrobial agents 20070601
Title: Usefulness of PCR strategies for early diagnosis of Chagas' disease reactivation and treatment follow-up in heart transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601
Title: Chagas' disease reactivation with skin symptoms in a patient with kidney transplant.
Journal: International journal of dermatology 20070601
Title: Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070401
Title: The Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole.
Journal: Antimicrobial agents and chemotherapy 20070401
Title: Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and structure-activity relationships.
Journal: Bioorganic & medicinal chemistry 20070401
Title: In vitro and in vivo trypanocidal activity of the ethyl esters of N-allyl and N-propyl oxamates using different Trypanosoma cruzi strains.
Journal: Journal of enzyme inhibition and medicinal chemistry 20070401
Title: In vitro and in vivo activity of lignan lactones derivatives against Trypanosoma cruzi.
Journal: Parasitology research 20070301
Title: Liver transplantation from deceased donors serologically positive for Chagas disease.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
Title: 1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi.
Journal: Bioorganic & medicinal chemistry 20070301
Title: [Chest pain and peripheral eosinophilia].
Journal: Revista clinica espanola 20070201
Title: Effects of canthin-6-one alkaloids from Zanthoxylum chiloperone on Trypanosoma cruzi-infected mice.
Journal: Journal of ethnopharmacology 20070119
Title: Synthesis and trypanocidal activity of ent-kaurane glycosides.
Journal: Bioorganic & medicinal chemistry 20070101
Title: Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series.
Journal: Bioorganic & medicinal chemistry 20070101
Title: Manifestations of Chagas disease (American trypanosomiasis) in patients with HIV/AIDS.
Journal: Annals of tropical medicine and parasitology 20070101
Title: Trypanocide treatment among adults with chronic Chagas disease living in Santa Fe city (Argentina), over a mean follow-up of 21 years: parasitological, serological and clinical evolution.
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20070101
Title: Novel potential drug against T. cruzi and its interaction with surfactant micelles.
Journal: Pharmaceutical development and technology 20070101
Title: Chagas disease: an impediment in achieving the Millennium Development Goals in Latin America.
Journal: BMC international health and human rights 20070101
Title: Mexican Trypanosoma cruzi isolates: in vitro susceptibility of epimastigotes to anti-trypanosoma cruzi drugs and metacyclic forms to complement-mediated lysis.
Journal: Vector borne and zoonotic diseases (Larchmont, N.Y.) 20070101
Title: Mitochondrial bioenergetics after nine-day treatment regimen with benzonidazole in rats.
Journal: International journal of toxicology 20070101
Title: An insight on targets and patented drugs for chemotherapy of Chagas disease.
Journal: Recent patents on anti-infective drug discovery 20070101
Title: New prescriptions for neglected diseases.
Journal: Open medicine : a peer-reviewed, independent, open-access journal 20070101
Title: Electrocardiographic findings in acutely and chronically T. cruzi-infected mice treated by a phenyl-substituted analogue of furamidine DB569.
Journal: Drug target insights 20070101
Title: Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.
Journal: Drug target insights 20070101
Title: Trypanosoma cruzi: alteration in the lymphoid compartments following interruption of infection by early acute benznidazole therapy in mice.
Journal: Experimental parasitology 20061101
Title: Synthesis and trypanocidal activity of 1,4-bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol and 1,4-bis-(3,4-dimethoxyphenyl)-1,4-butanediol.
Journal: Bioorganic & medicinal chemistry 20061101
Title: Benznidazole treatment during early-indeterminate Chagas' disease shifted the cytokine expression by innate and adaptive immunity cells toward a type 1-modulated immune profile.
Journal: Scandinavian journal of immunology 20061101
Title: In vitro antiprotozoal activity of the lipophilic extracts of different parts of Turkish Pistacia vera L.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20061101
Title: Increased expression of iron-containing superoxide dismutase-A (TcFeSOD-A) enzyme in Trypanosoma cruzi population with in vitro-induced resistance to benznidazole.
Journal: Acta tropica 20061101
Title: Activity of neolignans isolated from Piper regnellii (MIQ.) C. DC. var. pallescens (C. DC.) YUNCK against Trypanosoma cruzi.
Journal: Biological & pharmaceutical bulletin 20061001
Title: Detection of parasitemia profiles by blood culture after treatment of human chronic Trypanosoma cruzi infection.
Journal: Parasitology research 20060901
Title: Noncommunicable diseases and injuries in Latin America and the Caribbean: time for action.
Journal: PLoS medicine 20060901
Title: Polymerase chain reaction detection and serologic follow-up after treatment with benznidazole in Bolivian children infected with a natural mixture of Trypanosoma cruzi I and II.
Journal: The American journal of tropical medicine and hygiene 20060901
Title: Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium.
Journal: Bioorganic & medicinal chemistry 20060815
Title: Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis).
Journal: Human & experimental toxicology 20060801
Title: Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of Trypanosoma cruzi dUTPase.
Journal: Bioorganic & medicinal chemistry letters 20060715
Title: Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes.
Journal: Parasitology research 20060701
Title: 2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents.
Journal: Journal of medicinal chemistry 20060601
Title: The thymus is a common target organ in infectious diseases.
Journal: PLoS pathogens 20060601
Title: Summaries for patients. Long-term outcomes of treating nonacute Chagas disease with benznidazole.
Journal: Annals of internal medicine 20060516
Title: Long-term cardiac outcomes of treating chronic Chagas disease with benznidazole versus no treatment: a nonrandomized trial.
Journal: Annals of internal medicine 20060516
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Chagas disease: hidden affliction and visible neglect.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060411
Title: Deletion of copies of the gene encoding old yellow enzyme (TcOYE), a NAD(P)H flavin oxidoreductase, associates with in vitro-induced benznidazole resistance in Trypanosoma cruzi.
Journal: Molecular and biochemical parasitology 20060401
Title: Treatment of experimental chronic chagas disease with trifluralin.
Journal: Basic & clinical pharmacology & toxicology 20060401
Title: Development of parenteral formulations and evaluation of the biological activity of the trypanocide drug benznidazole.
Journal: International journal of pharmaceutics 20060113
Title: Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N'-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides.
Journal: European journal of medicinal chemistry 20060101
Title: Diterpenoid alkaloid derivatives as potential chemotherapeutic agents in American trypanosomiasis.
Journal: Pharmacology 20060101
Title: [Recommendations for diagnosis, treatment and follow-up of the Trypanosoma cruzi: human immunodeficiency virus co-infection].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20060101
Title: Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral Chagas disease in a patient with AIDS.
Journal: The American journal of tropical medicine and hygiene 20051201
Title: Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate.
Journal: Journal of medicinal chemistry 20051117
Title: The need of a neonatal preparation for Chagas disease.
Journal: PLoS medicine 20051101
Title: Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection).
Journal: The Cochrane database of systematic reviews 20051019
Title: Trypanosoma cruzi: chemotherapeutic effects of clomipramine in mice infected with an isolate obtained from an endemic area.
Journal: Experimental parasitology 20051001
Title: Transmission of T. cruzi infection via liver transplantation to a nonreactive recipient for Chagas' disease.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050901
Title: [Mechanisms responsible for myocardial damage progression in chronic Chagas' disease].
Journal: Revista espanola de cardiologia 20050901
Title: [Clinical predictors of chronic chagasic myocarditis progression].
Journal: Revista espanola de cardiologia 20050901
Title: Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites.
Journal: Journal of medicinal chemistry 20050825
Title: Chagas disease in bone marrow transplantation: an approach to preemptive therapy.
Journal: Bone marrow transplantation 20050701
Title: Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound.
Journal: Journal of natural products 20050501
Title: ent-Dioncophylleine A and related dehydrogenated naphthylisoquinoline alkaloids, the first Asian dioncophyllaceae-type alkaloids, from the 'new'plant species Ancistrocladus benomensis.
Journal: Journal of natural products 20050501
Title: Benznidazole-induced genotoxicity in diploid cells of Aspergillus nidulans.
Journal: Memorias do Instituto Oswaldo Cruz 20050501
Title: Trypanocidal activity of N-isopropyl oxamate on cultured epimastigotes and murine trypanosomiasis using different Trypanosoma cruzi strains.
Journal: Journal of enzyme inhibition and medicinal chemistry 20050401
Title: Benznidazole vs benznidazole in multilamellar liposomes: how different they interact with blood components?
Journal: Memorias do Instituto Oswaldo Cruz 20050401
Title: A new pharmacological screening assay with Trypanosoma cruzi epimastigotes expressing beta-galactosidase.
Journal: Parasitology research 20050301
Title: Amino acid metabolic routes in Trypanosoma cruzi: possible therapeutic targets against Chagas' disease.
Journal: Current drug targets. Infectious disorders 20050301
Title: The trypanocidal effect of sesquiterpene lactones helenalin and mexicanin on cultured epimastigotes.
Journal: The Journal of parasitology 20050201
Title: Response to chemotherapy with benznidazole of clones isolated from the 21SF strain of Trypanosoma cruzi (biodeme Type II, Trypanosoma cruzi II).
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20050101
Title: [Treatment of Chagas disease with benznidazole and thioctic acid].
Journal: Medicina 20050101
Title: [Implementation and evaluation of a locally sustainable system of prenatal diagnosis to detect cases of congenital Chagas disease in endemic areas of Paraguay].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20050101
Title: Benznidazole, a drug used in Chagas' disease, ameliorates LPS-induced inflammatory response in mice.
Journal: Life sciences 20041224
Title: Ancistrobenomine a, the first naphthylisoquinoline oxygenated at Me-3, and related 5,1'-coupled alkaloids, from the 'new' plant species ancistrocladusbenomensis.
Journal: Journal of natural products 20041201
Title: Trypanosoma cruzi: inhibition of alpha-hydroxyacid dehydrogenase isozyme II by N-allyl and N-propyl oxamates and their effects on intact epimastigotes.
Journal: Memorias do Instituto Oswaldo Cruz 20041201
Title: Short report: benznidazole efficacy among Trypanosoma cruzi-infected adolescents after a six-year follow-up.
Journal: The American journal of tropical medicine and hygiene 20041101
Title: Intravenous liposomal benznidazole as trypanocidal agent: increasing drug delivery to liver is not enough.
Journal: International journal of pharmaceutics 20040708
Title: Effects of specific treatment on parasitological and histopathological parameters in mice infected with different Trypanosoma cruzi clonal genotypes.
Journal: The Journal of antimicrobial chemotherapy 20040601
Title: Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives.
Journal: Farmaco (Societa chimica italiana : 1989) 20040601
Title: Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.
Journal: Journal of natural products 20040501
Title: Chagas seropositive donors in kidney transplantation.
Journal: Transplantation proceedings 20040501
Title: In vitro activity of Etanidazole against the protozoan parasite Trypanosoma cruzi.
Journal: Memorias do Instituto Oswaldo Cruz 20040301
Title: [Treatment of Chagas disease with benznidazole and thioctic acid].
Journal: Medicina 20040101
Title: Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
Journal: Biological research 20040101
Title: [Longitudinal study and specific chemotherapy in children with chronic Chagas' disease, residing in a low endemicity area of Argentina].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20040101
Title: Lack of correlation between in vitro susceptibility to Benznidazole and phylogenetic diversity of Trypanosoma cruzi, the agent of Chagas disease.
Journal: Experimental parasitology 20040101
Title: Benznidazole-induced ultrastructural and biochemical alterations in rat esophagus.
Journal: Toxicology 20030930
Title: Synthesis and evaluation of a series of 1,4-diarylbutadienes for anticoccidial activity.
Journal: Bioorganic & medicinal chemistry 20030901
Title: Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment.
Journal: Clinical and diagnostic laboratory immunology 20030901
Title: Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis.
Journal: Journal of natural products 20030901
Title: Liposomal benznidazole: a high-performance liquid chromatographic determination for biodistribution studies.
Journal: Journal of chromatographic science 20030901
Title: Trypanosoma cruzi: genetic group with peculiar biochemical and biological behavior.
Journal: Memorias do Instituto Oswaldo Cruz 20030701
Title: The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani.
Journal: Bioorganic & medicinal chemistry letters 20030616
Title: Synthesis and in vitro trypanocide activity of several polycyclic drimane-quinone derivatives.
Journal: Bioorganic & medicinal chemistry 20030612
Title: Nitroheterocyclic drugs with broad spectrum activity.
Journal: Parasitology research 20030601
Title: Inhibition of Trypanosoma cruzi alpha-hydroxyacid dehydrogenase-isozyme II by N-isopropyl oxamate and its effect on intact epimastigotes.
Journal: Journal of enzyme inhibition and medicinal chemistry 20030601
Title: Synthesis and biological evaluation of pyrazolylnaphthoquinones as new potential antiprotozoal and cytotoxic agents.
Journal: Chembiochem : a European journal of chemical biology 20030103
Title: [Anti-F2/3 antibodies as cure marker in children with congenital Trypanosoma cruzi infection].
Journal: Medicina 20030101
Title: Trypanosoma cruzi: susceptibility to chemotherapy with benznidazole of clones isolated from the highly resistant Colombian strain.
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20030101
Title: Treatment with benznidazole in association with immunosuppressive drugs in mice chronically infected with Trypanosoma cruzi: investigation into the possible development of neoplasias.
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20030101
Title: [Trypanosoma cruzi high parasitemia in patient with systemic lupus erythematosus].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20030101
Title: Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines.
Journal: European journal of medicinal chemistry 20030101
Title: Development and in vitro characterisation of a benznidazole liposomal formulation.
Journal: International journal of pharmaceutics 20021205
Title: Relationship between long-term resistance to Trypanosoma cruzi and latent infection, examined by antibody production and polymerase chain reaction in mice.
Journal: The Journal of parasitology 20021201
Title: Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain.
Journal: Memorias do Instituto Oswaldo Cruz 20021201
Title: Chemotherapy of Chagas' disease: status and new developments.
Journal: Current topics in medicinal chemistry 20021101
Title: Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.
Journal: Antimicrobial agents and chemotherapy 20021101
Title: The dog as model for chemotherapy of the Chagas' disease.
Journal: Acta tropica 20021001
Title: Experimental chemotherapy against Trypanosoma cruzi infection: essential role of endogenous interferon-gamma in mediating parasitologic cure.
Journal: The Journal of infectious diseases 20020915
Title: Cerebral trypanosomiasis and AIDS.
Journal: Arquivos de neuro-psiquiatria 20020901
Title: Ancistrocongolines A-D, new naphthylisoquinoline alkaloids from ancistrocladus congolensis.
Journal: Journal of natural products 20020801
Title: Voltammetric behavior of benznidazole at a DNA-electrochemical biosensor.
Journal: Journal of pharmaceutical and biomedical analysis 20020701
Title: Trypanosoma cruzi trypanothione reductase inhibitors: phenothiazines and related compounds modify experimental Chagas' disease evolution.
Journal: Current drug targets. Cardiovascular & haematological disorders 20020601
Title: The restoring effect of trifluralin and benznidazole on the abnormal fatty-acid pattern induced by Trypanosoma cruzi in the liver microsomes of infected mice.
Journal: Annals of tropical medicine and parasitology 20020401
Title: In vitro and in vivo assays of 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives against Trypanosoma cruzi.
Journal: Memorias do Instituto Oswaldo Cruz 20020301
Title: African trypanosomiasis in travelers returning to the United Kingdom.
Journal: Emerging infectious diseases 20020101
Title: Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection.
Journal: The Cochrane database of systematic reviews 20020101
Title: Long term evaluation of etiological treatment of chagas disease with benznidazole.
Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20020101
Title: A critical review on Chagas disease chemotherapy.
Journal: Memorias do Instituto Oswaldo Cruz 20020101
Title: TNF-alpha is expressed at sites of parasite and tissue destruction in the spleen of mice acutely infected with Trypanosoma cruzi.
Journal: International journal of experimental pathology 20011201
Title: Experimental treatment of chronic Trypanosoma cruzi infection in mice with 2-n-propylquinoline.
Journal: Phytotherapy research : PTR 20011101
Title: Anti-Trypanosoma activity of some natural stilbenoids and synthetic related heterocyclic compounds.
Journal: Bioorganic & medicinal chemistry letters 20011022
Title: Drug resistance in Trypanosoma cruzi is not associated with amplification or overexpression of P-glycoprotein (PGP) genes.
Journal: Molecular and biochemical parasitology 20011001
Title: Variation in susceptibility to benznidazole in isolates derived from Trypanosoma cruzi parental strains.
Journal: Memorias do Instituto Oswaldo Cruz 20011001
Title: Trypanocidal drug benznidazole impairs lipopolysaccharide induction of macrophage nitric oxide synthase gene transcription through inhibition of NF-kappaB activation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010915
Title: Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds.
Journal: Bioorganic & medicinal chemistry letters 20010723
Title: Treatment with benznidazole and its immunomodulating effects on Trypanosoma cruzi-infected rats.
Journal: Parasitology research 20010701
Title: Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design.
Journal: Journal of medicinal chemistry 20010621
Title: Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy.
Journal: Journal of medicinal chemistry 20010315
Title: A disubstituted NAD+ analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase.
Journal: Bioorganic & medicinal chemistry letters 20010122
Title: Biological characterization of Trypanosoma cruzi strains.
Journal: Memorias do Instituto Oswaldo Cruz 20010101
Title: New thiadiazine derivatives with activity against Trypanosoma cruzi amastigotes.
Journal: Folia parasitologica 20010101
Title: Time-dependent oxidative stress caused by benznidazole.
Journal: Redox report : communications in free radical research 20010101
Title: Trypanocidal activity of 4 isopropyl salicylaldehyde and 4-isopropyl salicylic acid on Trypanosoma cruzi.
Journal: Revista latinoamericana de microbiologia 20010101
Title: Treatment of experimental pneumocystosis: review of 7 years of experience and development of a new system for classifying antimicrobial drugs.
Journal: Antimicrobial agents and chemotherapy 19920901
Title: Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU.
Journal: British journal of cancer 19820801
Title: Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships.
Journal: International journal of radiation oncology, biology, physics 19820101
Title: Single-dose pharmacokinetics of the trypanosomicide benznidazole in man.
Journal: Arzneimittel-Forschung 19790101
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