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23696-28-8,MFCD00210341
Catalog No.:AA002O3U

23696-28-8 | Olaquindox

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25mg
99%(HPLC)
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$48.00   $34.00
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100mg
99%(HPLC)
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$112.00   $78.00
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250mg
≥98%
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$270.00   $189.00
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500mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002O3U
Chemical Name:
Olaquindox
CAS Number:
23696-28-8
Molecular Formula:
C12H13N3O4
Molecular Weight:
263.2493
MDL Number:
MFCD00210341
SMILES:
OCCNC(=O)c1c(C)[n+]([O-])c2c([n+]1[O-])cccc2
NSC Number:
634933
Properties
Computed Properties
 
Complexity:
421  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-0.2  

Literature

Title: Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171001

Title: High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells.

Journal: Toxicology 20160203

Title: Reactive oxygen species-dependent JNK downregulated olaquindox-induced autophagy in HepG2 cells.

Journal: Journal of applied toxicology : JAT 20150701

Title: Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901

Title: Determination of Carbadox and metabolites of Carbadox and Olaquindox in muscle tissue using high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120115

Title: Development of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.

Journal: PloS one 20120101

Title: Molecularly imprinted solid-phase extraction combined with high-performance liquid chromatography for analysis of trace olaquindox residues in chick feeds.

Journal: Journal of the science of food and agriculture 20111001

Title: Olaquindox induces apoptosis through the mitochondrial pathway in HepG2 cells.

Journal: Toxicology 20110729

Title: Metabolism of olaquindox in rat and identification of metabolites in urine and feces using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20110415

Title: Determination of marker residue of Olaquindox in fish tissue by ultra performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of separation science 20110201

Title: Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats.

Journal: Regulatory toxicology and pharmacology : RTP 20101201

Title: The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken.

Journal: Toxicology letters 20100519

Title: ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro.

Journal: Chemico-biological interactions 20100514

Title: Olaquindox-induced genotoxicity and oxidative DNA damage in human hepatoma G2 (HepG2) cells.

Journal: Mutation research 20090531

Title: A determinative and confirmatory method for residues of the metabolites of carbadox and olaquindox in porcine tissues.

Journal: Analytica chimica acta 20090401

Title: Risk assessment of ciprofloxacin, flavomycin, olaquindox and colistin sulfate based on microbiological impact on human gut biota.

Journal: Regulatory toxicology and pharmacology : RTP 20090401

Title: Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090201

Title: Matrix solid-phase dispersion extraction of carbadox and olaquindox in feed followed by hydrophilic interaction ultra-high-pressure liquid chromatographic analysis.

Journal: Journal of chromatography. A 20081031

Title: A highly sensitive and specific polyclonal antibody-based enzyme-linked immunosorbent assay for detection of antibiotic olaquindox in animal feed samples.

Journal: Analytical and bioanalytical chemistry 20080801

Title: Metabolism of olaquindox in rat liver microsomes: structural elucidation of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20080401

Title: Validation of an analytical method for the determination of carbadox and olaquindox in feedstuff by liquid chromatography coupled to UV and/or diode array detection.

Journal: Food additives and contaminants 20071101

Title: Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria.

Journal: The Journal of antimicrobial chemotherapy 20070701

Title: Disabling work-related persistent photosensitivity following photoallergic contact dermatitis from chlorpromazine and olaquindox in a pig breeder.

Journal: Annals of agricultural and environmental medicine : AAEM 20070101

Title: Molecular mechanism of mutagenesis induced by olaquindox using a shuttle vector pSP189/mammalian cell system.

Journal: Mutation research 20060725

Title: Sorption of tylosin onto swine manure.

Journal: Chemosphere 20050701

Title: [Toxicological study of three veterinary drugs on Eisenia foetida].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20050601

Title: Confirmation of carbadox and olaquindox metabolites in porcine liver using liquid chromatography-electrospray, tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: Confirmatory method for the analysis of carbadox and olaquindox in porcine feedingstuffs using LC-electrospray MS-MS.

Journal: Food additives and contaminants 20050201

Title: The prevalence of the OqxAB multidrug efflux pump amongst olaquindox-resistant Escherichia coli in pigs.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20050101

Title: The effect of antimicrobial growth promoter withdrawal on the health of weaned pigs in Finland.

Journal: Preventive veterinary medicine 20041215

Title: Effects of the antibacterial agents tiamulin, olanquindox and metronidazole and the anthelmintic ivermectin on the soil invertebrate species Folsomia fimetaria (Collembola) and Enchytraeus crypticus (Enchytraeidae).

Journal: Chemosphere 20030101

Title: Discriminative stimulus properties in rats of the novel antipsychotic quetiapine.

Journal: Experimental and clinical psychopharmacology 20021101

Title: Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure.

Journal: Chemosphere 20020701

Title: High-performance liquid chromatographic determination of carbadox, olaquindox, furazolidone, nitrofurazone, and nitrovin in feed.

Journal: Journal of food protection 20010801

Title: Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil--manure slurries.

Journal: Ecotoxicology and environmental safety 20010301

Title: Ding MX, et al. Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunityof piglets orally inoculated with Escherichia coli. J Anim Physiol Anim Nutr (Berl). 2006 Jun;90(5-6):238-43.

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