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24735-18-0,MFCD09953249
Catalog No.:AA002P78

24735-18-0 | Leonurine Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98% by HPLC
in stock  
$156.00   $109.00
- +
10mg
98% by HPLC
in stock  
$219.00   $153.00
- +
25mg
98% by HPLC
in stock  
$392.00   $274.00
- +
50mg
98% by HPLC
in stock  
$622.00   $435.00
- +
100mg
98% by HPLC
in stock  
$1,029.00   $720.00
- +
250mg
99%
in stock  
$2,266.00   $1,587.00
- +
500mg
98% by HPLC
in stock  
$3,179.00   $2,226.00
- +
1000mg
98% by HPLC
in stock  
$5,049.00   $3,534.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002P78
Chemical Name:
Leonurine Hydrochloride
CAS Number:
24735-18-0
Molecular Formula:
C14H22ClN3O5
Molecular Weight:
347.7946
MDL Number:
MFCD09953249
SMILES:
COc1cc(cc(c1O)OC)C(=O)OCCCCNC=NN.Cl
Properties
Computed Properties
 
Complexity:
360  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
9  

Downstream Synthesis Route
24735-18-0    2528-61-2   
C35H57N3O10 

[1]CurrentPatentAssignee:BEIJINGHELIZHONGYINGMEDICINETECH-CN108840808,2018,ALocationinpatent:Paragraph0047-0050

33758-34-8    24735-18-0   
C22H35N3O7 

[1]CurrentPatentAssignee:BEIJINGHELIZHONGYINGMEDICINETECH-CN108840808,2018,ALocationinpatent:Paragraph0071-0074

6092-54-2    24735-18-0   
C21H33N3O7 

[1]Patent:CN108840808,2018,A.Locationinpatent:Paragraph0079-0082

Literature

Title: Jiang T, et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. Cell Physiol Biochem. 2017;43(4):1703-1717.

Title: Zhang L, et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway. Biomed Pharmacother. 2018 Dec 7;110:571-581.

Title: Hu ZC, et al. Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. J Cell Physiol. 2018 Nov 11.

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SDS
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