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2516-93-0,MFCD00067044
Catalog No.:AA002QMC

2516-93-0 | 2-Butoxyacetic acid

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1g
98%
in stock  
$37.00   $26.00
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5g
98%
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$95.00   $67.00
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10g
98%
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$162.00   $113.00
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25g
98%
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$339.00   $238.00
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100g
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$1,007.00   $705.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002QMC
Chemical Name:
2-Butoxyacetic acid
CAS Number:
2516-93-0
Molecular Formula:
C6H12O3
Molecular Weight:
132.1577
MDL Number:
MFCD00067044
SMILES:
CCCCOCC(=O)O
NSC Number:
10980
Properties
Properties
 
BP:
239.5°C at 760 mmHg  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
80.4  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
0.9  

Literature

Title: Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment.

Journal: Occupational and environmental medicine 20120101

Title: Biological monitoring of low-level 2-butoxyethanol exposure in decal transfer workers in bicycle manufacturing factories.

Journal: Occupational and environmental medicine 20111001

Title: Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion.

Journal: Clinical toxicology (Philadelphia, Pa.) 20100701

Title: Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites.

Journal: Toxicology and applied pharmacology 20100601

Title: Determination of butoxyacetic acid (biomarker of ethylene glycol monobutyl ether exposure) in human urine candidate reference material.

Journal: Analytical and bioanalytical chemistry 20100501

Title: The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100101

Title: Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared with the in vivo potency of their parent compounds.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701

Title: Metabolism of butoxyethanol in excised human skin in vitro.

Journal: Toxicology letters 20080401

Title: Potential for metabolism locally in the skin of dermally absorbed compounds.

Journal: Human & experimental toxicology 20080401

Title: Metabolism and disposition of n-butyl glycidyl ether in F344 rats and B6C3F1 mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Priming dose of phenylhydrazine protects against hemolytic and lethal effects of 2-butoxyethanol.

Journal: Toxicology and applied pharmacology 20071115

Title: Development of a gas chromatographic test for the quantitation of the biomarker 2-butoxyacetic acid in urine samples.

Journal: Journal of chromatographic science 20070801

Title: Percutaneous absorption and metabolism of 2-butoxyethanol in human volunteers: a microdialysis study.

Journal: Toxicology letters 20070425

Title: Pyrazole and methylpyrazole for the treatment of 2-butoxyethanol poisoning.

Journal: Acta poloniae pharmaceutica 20070101

Title: Mechanisms of 2-butoxyethanol-induced hemangiosarcomas.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801

Title: Gas chromatography analysis of urinary alkoxyacetic acids as biomarkers of exposure to aliphatic alkyl ethers.

Journal: Journal of analytical toxicology 20060501

Title: Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanol.

Journal: Toxicology letters 20060410

Title: Comparison and evaluation of analysis procedures for the quantification of (2-methoxyethoxy)acetic acid in urine.

Journal: Analytical and bioanalytical chemistry 20050901

Title: INRS activities on risk assessment of glycol ethers.

Journal: Toxicology letters 20050328

Title: Butoxyacetic acid-induced hemolysis of rat red blood cells: effect of external osmolarity and cations.

Journal: Toxicology letters 20050328

Title: Effects of diethylene glycol butyl ether and butoxyethoxyacetic acid on rat and human erythrocytes.

Journal: Toxicology letters 20050328

Title: Mode of action of butoxyethanol-induced mouse liver hemangiosarcomas and hepatocellular carcinomas.

Journal: Toxicology letters 20050328

Title: Determination of age and gender differences in biochemical processes affecting the disposition of 2-butoxyethanol and its metabolites in mice and rats to improve PBPK modeling.

Journal: Toxicology letters 20050328

Title: A Test Procedure for the Determination of (2-Methoxyethoxy)acetic Acid in Urine from Jet Fuel-Exposed Mice.

Journal: Toxicology mechanisms and methods 20050101

Title: Percutaneous penetration and metabolism of 2-butoxyethanol.

Journal: Archives of toxicology 20041101

Title: Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers.

Journal: International archives of occupational and environmental health 20041101

Title: Determination of urinary metabolites of alkyl cellosolves by solid phase extraction and GC/FID.

Journal: Journal of occupational health 20040701

Title: In vivo metabolism and kinetics of ethylene glycol monobutyl ether and its metabolites, 2-butoxyacetaldehyde and 2-butoxyacetic acid, as measured in blood, liver and forestomach of mice.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040701

Title: Percutaneous absorption of neat and aqueous solutions of 2-butoxyethanol in volunteers.

Journal: International archives of occupational and environmental health 20040201

Title: Synthesis, characterization, and use of 2-[(2H(9))butoxy]acetic acid and 2-(3-methylbutoxy)acetic acid as an internal standard and an instrument performance surrogate, respectively, for the gas chromatographic-mass spectrometric determination of 2-butoxyacetic acid, a human metabolite of 2-butoxyethanol.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725

Title: Mode of action and pharmacokinetic studies of 2-butoxyethanol in the mouse with an emphasis on forestomach dosimetry.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030201

Title: A human exposure study to investigate biological monitoring methods for 2-butoxyethanol.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101

Title: The development of forestomach tumours in the mouse following exposure to 2-butoxyethanol by inhalation: studies on the mode of action and relevance to humans.

Journal: Toxicology 20021202

Title: In vitro sub-hemolytic effects of butoxyacetic acid on human and rat erythrocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020901

Title: Mechanisms of 2-butoxyethanol carcinogenicity: studies on Syrian Hamster Embryo (SHE) cell transformation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020701

Title: Effects of 2-butoxyethanol on hepatic oxidative damage.

Journal: Toxicology letters 20020105

Title: Suppression of the contact hypersensitivity response following topical exposure to 2-butoxyethanol in female BALB/c mice.

Journal: International journal of toxicology 20020101

Title: Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.

Journal: Toxicology and applied pharmacology 19850701

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