26289-39-4,MFCD01863384
Catalog No.:AA002SJ7

26289-39-4 | Glycine, L-γ-glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl-

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1mg
≥98%
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5mg
≥98%
in stock  
$309.00   $216.00
- +
100mg
95%
in stock  
$383.00   $268.00
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1g
95%
in stock  
$1,424.00   $997.00
- +
5g
95%
in stock  
$4,235.00   $2,964.00
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10g
95%
in stock  
$6,780.00 $4,746.00
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA002SJ7
Chemical Name:
Glycine, L-γ-glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl-
CAS Number:
26289-39-4
Molecular Formula:
C16H19N5O10S
Molecular Weight:
473.4146
MDL Number:
MFCD01863384
SMILES:
O=C(N[C@H](C(=O)NCC(=O)O)CSc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])CC[C@@H](C(=O)O)N
Properties
Computed Properties
 
Complexity:
740  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
11  
XLogP3:
-2.9  

Literature

Title: Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120701

Title: Application of human placental villous tissue explants to study ABC transporter mediated efflux of 2,4-dinitrophenyl-S-glutathione.

Journal: Current pharmaceutical biotechnology 20110501

Title: Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.

Journal: The FEBS journal 20110101

Title: Modulated function of tissue efflux transporters under hyperbilirubinemia in rats.

Journal: European journal of pharmacology 20100625

Title: Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats.

Journal: Die Pharmazie 20100501

Title: Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.

Journal: European journal of pharmacology 20091125

Title: Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro.

Journal: International journal of pharmaceutics 20091103

Title: Effect of ursodeoxycholic acid treatment on the expression and function of multidrug resistance-associated protein 2 in rat intestine.

Journal: Journal of pharmaceutical sciences 20090801

Title: Physiological and pharmacological significance of glutathione-conjugate transport.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews 20090801

Title: Aged garlic extract stimulates p-glycoprotein and multidrug resistance associated protein 2 mediated effluxes.

Journal: Biological & pharmaceutical bulletin 20090401

Title: Association mechanism of S-dinitrophenyl glutathione with two glutathione peroxidase mimics: 2, 2 cent-ditelluro- and 2, 2 cent-diseleno-bridged b-cyclodextrins.

Journal: Molecules (Basel, Switzerland) 20090225

Title: Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates.

Journal: International journal of oncology 20090101

Title: Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments.

Journal: Molecular pharmaceutics 20090101

Title: Simultaneous determination of 1-chloro-2,4-dinitrobenzene, 2,4-dinitrophenyl-S-glutathione and its metabolites for human placental disposition studies by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101

Title: Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells.

Journal: The Journal of pharmacy and pharmacology 20070401

Title: Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.

Journal: European journal of pharmacology 20060928

Title: Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.

Journal: Epilepsy research 20060901

Title: Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060801

Title: Increased glutathione conjugate transport: a possible compensatory protection mechanism against oxidative stress in obesity?

Journal: International journal of obesity (2005) 20060101

Title: Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

Journal: The FEBS journal 20050901

Title: Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes.

Journal: Biochemical pharmacology 20050815

Title: Modulation of intestinal transport of 2,4-dinitrophenyl-S-glutathione, a multidrug resistance-associated protein 2 substrate, by bilirubin treatment in rats.

Journal: The Journal of pharmacy and pharmacology 20050501

Title: Treatment of hyperbilirubinemia in Eisai hyperbilirubinemic rat by transfecting human MRP2/ABCC2 gene.

Journal: Pharmaceutical research 20050401

Title: Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050301

Title: Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.

Journal: Biochemical pharmacology 20050201

Title: Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein.

Journal: Biochemical pharmacology 20040815

Title: Biliary secretory function in rats chronically intoxicated with aluminum.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501

Title: Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.

Journal: Biochemical pharmacology 20040415

Title: Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

Journal: The international journal of biochemistry & cell biology 20040201

Title: Do multidrug resistance-associated protein-1 and -2 play any role in the elimination of estradiol-17 beta-glucuronide and 2,4-dinitrophenyl-S-glutathione across the blood-cerebrospinal fluid barrier?

Journal: Journal of pharmaceutical sciences 20040101

Title: Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts.

Journal: Biochemical and biophysical research communications 20031024

Title: cGMP and glutathione-conjugate transport in human erythrocytes.

Journal: European journal of biochemistry 20030901

Title: Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells.

Journal: Investigative ophthalmology & visual science 20030801

Title: Expression of rat hepatic multidrug resistance-associated proteins and organic anion transporters in pregnancy.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020901

Title: Altered localization and activity of canalicular Mrp2 in estradiol-17beta-D-glucuronide-induced cholestasis.

Journal: Hepatology (Baltimore, Md.) 20020601

Title: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

Journal: Journal of the American Society of Nephrology : JASN 20020301

Title: Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells.

Journal: European journal of biochemistry 20011201

Title: Energy-dependent export of the 13-oxooctadecadienoic acid-glutathione conjugate from HT-29 cells and plasma membrane vesicles.

Journal: Biochimica et biophysica acta 20010829

Title: Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT).

Journal: The Journal of biological chemistry 20010615

Title: Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2.

Journal: Molecular pharmacology 20010501

Title: Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.

Journal: Hepatology (Baltimore, Md.) 20010501

Title: Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT).

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010501

Title: Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences.

Journal: Biochemistry 20010403

Title: Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-dianninopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-homoglutamic acid, in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010401

Title: Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter.

Journal: Molecular pharmacology 19991201

Title: Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Journal: The Journal of clinical investigation 19980401

Title: Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver.

Journal: The Journal of biological chemistry 19980116

Title: Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).

Journal: The Journal of pharmacology and experimental therapeutics 19970301

Title: Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver.

Journal: The Journal of clinical investigation 19930601

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Related Products of 26289-39-4
Tags:26289-39-4 Molecular Formula|26289-39-4 MDL|26289-39-4 SMILES|26289-39-4 Glycine, L-γ-glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl-
Catalog No.: AA002SJ7
26289-39-4,MFCD01863384
26289-39-4 | Glycine, L-γ-glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl-
Pack Size: 1mg
Purity: ≥98%
in stock
$70.00 $49.00
Pack Size: 5mg
Purity: ≥98%
in stock
$309.00 $216.00
Pack Size: 100mg
Purity: 95%
in stock
$383.00 $268.00
Pack Size: 1g
Purity: 95%
in stock
$1,424.00 $997.00
Pack Size: 5g
Purity: 95%
in stock
$4,235.00 $2,964.00
Pack Size: 10g
Purity: 95%
in stock
$6,780.00 $4,746.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA002SJ7
Chemical Name: Glycine, L-γ-glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl-
CAS Number: 26289-39-4
Molecular Formula: C16H19N5O10S
Molecular Weight: 473.4146
MDL Number: MFCD01863384
SMILES: O=C(N[C@H](C(=O)NCC(=O)O)CSc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])CC[C@@H](C(=O)O)N
Properties
Complexity: 740  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 32  
Hydrogen Bond Acceptor Count: 12  
Hydrogen Bond Donor Count: 5  
Rotatable Bond Count: 11  
XLogP3: -2.9  
Literature fold

Title: Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Journal: Drug metabolism and disposition: the biological fate of chemicals20120701

Title: Application of human placental villous tissue explants to study ABC transporter mediated efflux of 2,4-dinitrophenyl-S-glutathione.

Journal: Current pharmaceutical biotechnology20110501

Title: Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.

Journal: The FEBS journal20110101

Title: Modulated function of tissue efflux transporters under hyperbilirubinemia in rats.

Journal: European journal of pharmacology20100625

Title: Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats.

Journal: Die Pharmazie20100501

Title: Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.

Journal: European journal of pharmacology20091125

Title: Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro.

Journal: International journal of pharmaceutics20091103

Title: Effect of ursodeoxycholic acid treatment on the expression and function of multidrug resistance-associated protein 2 in rat intestine.

Journal: Journal of pharmaceutical sciences20090801

Title: Physiological and pharmacological significance of glutathione-conjugate transport.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews20090801

Title: Aged garlic extract stimulates p-glycoprotein and multidrug resistance associated protein 2 mediated effluxes.

Journal: Biological & pharmaceutical bulletin20090401

Title: Association mechanism of S-dinitrophenyl glutathione with two glutathione peroxidase mimics: 2, 2 cent-ditelluro- and 2, 2 cent-diseleno-bridged b-cyclodextrins.

Journal: Molecules (Basel, Switzerland)20090225

Title: Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates.

Journal: International journal of oncology20090101

Title: Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments.

Journal: Molecular pharmaceutics20090101

Title: Simultaneous determination of 1-chloro-2,4-dinitrobenzene, 2,4-dinitrophenyl-S-glutathione and its metabolites for human placental disposition studies by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20071101

Title: Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells.

Journal: The Journal of pharmacy and pharmacology20070401

Title: Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.

Journal: European journal of pharmacology20060928

Title: Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.

Journal: Epilepsy research20060901

Title: Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060801

Title: Increased glutathione conjugate transport: a possible compensatory protection mechanism against oxidative stress in obesity?

Journal: International journal of obesity (2005)20060101

Title: Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

Journal: The FEBS journal20050901

Title: Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes.

Journal: Biochemical pharmacology20050815

Title: Modulation of intestinal transport of 2,4-dinitrophenyl-S-glutathione, a multidrug resistance-associated protein 2 substrate, by bilirubin treatment in rats.

Journal: The Journal of pharmacy and pharmacology20050501

Title: Treatment of hyperbilirubinemia in Eisai hyperbilirubinemic rat by transfecting human MRP2/ABCC2 gene.

Journal: Pharmaceutical research20050401

Title: Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20050301

Title: Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.

Journal: Biochemical pharmacology20050201

Title: Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein.

Journal: Biochemical pharmacology20040815

Title: Biliary secretory function in rats chronically intoxicated with aluminum.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20040501

Title: Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.

Journal: Biochemical pharmacology20040415

Title: Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

Journal: The international journal of biochemistry & cell biology20040201

Title: Do multidrug resistance-associated protein-1 and -2 play any role in the elimination of estradiol-17 beta-glucuronide and 2,4-dinitrophenyl-S-glutathione across the blood-cerebrospinal fluid barrier?

Journal: Journal of pharmaceutical sciences20040101

Title: Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts.

Journal: Biochemical and biophysical research communications20031024

Title: cGMP and glutathione-conjugate transport in human erythrocytes.

Journal: European journal of biochemistry20030901

Title: Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells.

Journal: Investigative ophthalmology & visual science20030801

Title: Expression of rat hepatic multidrug resistance-associated proteins and organic anion transporters in pregnancy.

Journal: American journal of physiology. Gastrointestinal and liver physiology20020901

Title: Altered localization and activity of canalicular Mrp2 in estradiol-17beta-D-glucuronide-induced cholestasis.

Journal: Hepatology (Baltimore, Md.)20020601

Title: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

Journal: Journal of the American Society of Nephrology : JASN20020301

Title: Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells.

Journal: European journal of biochemistry20011201

Title: Energy-dependent export of the 13-oxooctadecadienoic acid-glutathione conjugate from HT-29 cells and plasma membrane vesicles.

Journal: Biochimica et biophysica acta20010829

Title: Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT).

Journal: The Journal of biological chemistry20010615

Title: Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2.

Journal: Molecular pharmacology20010501

Title: Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.

Journal: Hepatology (Baltimore, Md.)20010501

Title: Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT).

Journal: Hypertension research : official journal of the Japanese Society of Hypertension20010501

Title: Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences.

Journal: Biochemistry20010403

Title: Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-dianninopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-homoglutamic acid, in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals20010401

Title: Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter.

Journal: Molecular pharmacology19991201

Title: Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Journal: The Journal of clinical investigation19980401

Title: Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver.

Journal: The Journal of biological chemistry19980116

Title: Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).

Journal: The Journal of pharmacology and experimental therapeutics19970301

Title: Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver.

Journal: The Journal of clinical investigation19930601

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