Home Other Building Blocks 26441-05-4
26441-05-4,MFCD09836267
Catalog No.:AA002T5H

26441-05-4 | Prosta-5,13-dien-1-oic acid, 11-hydroxy-9,15-dioxo-, (5Z,11α,13E)-

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1mg
≥98%
in stock  
$173.00   $121.00
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5mg
≥98%
in stock  
$722.00   $505.00
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10mg
≥98%
in stock  
$1,263.00   $884.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002T5H
Chemical Name:
Prosta-5,13-dien-1-oic acid, 11-hydroxy-9,15-dioxo-, (5Z,11α,13E)-
CAS Number:
26441-05-4
Molecular Formula:
C20H30O5
Molecular Weight:
350.4492
MDL Number:
MFCD09836267
SMILES:
CCCCCC(=O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O
Properties
Computed Properties
 
Complexity:
506  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  
XLogP3:
2.7  

Literature

Title: Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis.

Journal: Chemico-biological interactions 20150605

Title: 15-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy ω-3 fatty acids.

Journal: The Journal of biological chemistry 20150227

Title: Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase.

Journal: The Journal of biological chemistry 20130830

Title: A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules.

Journal: The Journal of biological chemistry 20100716

Title: Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.

Journal: Nature medicine 20100301

Title: Lipids control mucus production in cystic fibrosis.

Journal: Nature medicine 20100301

Title: Chinese hamster monomeric carbonyl reductases of the short-chain dehydrogenase/reductase superfamily.

Journal: Chemico-biological interactions 20090316

Title: Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.

Journal: Structure (London, England : 1993) 20081112

Title: Evidence for oxylipin synthesis and induction of a new polyunsaturated fatty acid hydroxylase activity in Chondrus crispus in response to methyljasmonate.

Journal: Biochimica et biophysica acta 20070501

Title: Structural insights into human serum albumin-mediated prostaglandin catalysis.

Journal: Protein science : a publication of the Protein Society 20020301

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Tags:26441-05-4 Molecular Formula|26441-05-4 MDL|26441-05-4 SMILES|26441-05-4 Prosta-5,13-dien-1-oic acid, 11-hydroxy-9,15-dioxo-, (5Z,11α,13E)-