Home Amines 2756-85-6
2756-85-6,MFCD00001487
Catalog No.:AA002TZP

2756-85-6 | 1-Aminocyclohexanecarboxylic acid

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1g
98%
in stock  
$29.00   $20.00
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5g
95%
in stock  
$36.00   $25.00
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25g
≥ 98% (Titration)
in stock  
$93.00   $65.00
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100g
≥ 98% (Titration)
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$221.00   $155.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002TZP
Chemical Name:
1-Aminocyclohexanecarboxylic acid
CAS Number:
2756-85-6
Molecular Formula:
C7H13NO2
Molecular Weight:
143.1836
MDL Number:
MFCD00001487
SMILES:
OC(=O)C1(N)CCCCC1
NSC Number:
9059
Properties
Properties
 
BP:
272.3±23.0°C at 760 mmHg  
Form:
Solid  
MP:
>300 °C(lit.)  
Refractive Index:
1.4150 (estimate)  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
139  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-1.9  

Literature

Title: Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).

Journal: Biochimica et biophysica acta 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex.

Journal: Journal of medicinal chemistry 20090827

Title: Redetermination of 1-carboxy-cyclo-hexan-1-aminium chloride.

Journal: Acta crystallographica. Section E, Structure reports online 20090201

Title: Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine.

Journal: Journal of medicinal chemistry 20081023

Title: cis-3-(tert-Butoxy-carbonyl-amino)cyclo-hexa-necarboxylic acid.

Journal: Acta crystallographica. Section E, Structure reports online 20080901

Title: Application of 1-aminocyclohexane carboxylic acid to protein nanostructure computer design.

Journal: Journal of chemical information and modeling 20080201

Title: An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.

Journal: PloS one 20070101

Title: New bradykinin analogues substituted in positions 7 and 8 with sterically restricted 1-aminocyclopentane-1-carboxylic acid.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20061201

Title: Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles.

Journal: Bioorganic & medicinal chemistry letters 20061015

Title: Raman and surface-enhanced Raman spectroscopy investigation of vasopressin analogues containing 1-aminocyclohexane-1-carboxylic acid residue.

Journal: Biopolymers 20061005

Title: New bradykinin analogues modified in the C-terminal part with sterically restricted 1-aminocyclohexane-1-carboxylic acid.

Journal: Journal of medicinal chemistry 20051215

Title: Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.

Journal: Journal of medicinal chemistry 20051201

Title: The influence of 1-aminocyclopentane-1-carboxylic acid at position 2 or 3 of AVP and its analogues on their pharmacological properties.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20050901

Title: Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.

Journal: Journal of medicinal chemistry 20050210

Title: Bioactive N-terminal undecapeptides derived from parathyroid hormone: the role of alpha-helicity.

Journal: The journal of peptide research : official journal of the American Peptide Society 20050101

Title: Highly potent 1-aminocyclohexane-1-carboxylic acid substituted V2 agonists of arginine vasopressin.

Journal: Journal of medicinal chemistry 20041118

Title: Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties.

Journal: The journal of peptide research : official journal of the American Peptide Society 20030801

Title: The structure of an endomorphin analogue incorporating 1-aminocyclohexane-1-carboxlylic acid for proline is similar to the beta-turn of Leu-enkephalin.

Journal: Biochemical and biophysical research communications 20020913

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Nitroxyl peptides as catalysts of enantioselective oxidations.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20020104

Title: Amphipathic control of the 3(10)-/alpha-helix equilibrium in synthetic peptides.

Journal: The journal of peptide research : official journal of the American Peptide Society 20010801

Title: Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques.

Journal: Analytical biochemistry 20010101

Title: Crystal-state conformation of Calpha,alpha-dialkylated peptides containing chiral beta-homo-residues.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20010101

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Tags:2756-85-6 Molecular Formula|2756-85-6 MDL|2756-85-6 SMILES|2756-85-6 1-Aminocyclohexanecarboxylic acid