Home Amines 302963-94-6
302963-94-6,MFCD01631191
Catalog No.:AA002ZGU

302963-94-6 | N-Boc-amino-4-methylthiazole-5-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$16.00   $11.00
- +
1g
95%
in stock  
$33.00   $23.00
- +
5g
95%
in stock  
$159.00   $111.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002ZGU
Chemical Name:
N-Boc-amino-4-methylthiazole-5-carboxylic acid
CAS Number:
302963-94-6
Molecular Formula:
C10H14N2O4S
Molecular Weight:
258.2942
MDL Number:
MFCD01631191
SMILES:
O=C(OC(C)(C)C)Nc1nc(c(s1)C(=O)O)C
Properties
Properties
 
Form:
Solid  
Storage:
2-8℃;Keep in dry area;  

Computed Properties
 
Complexity:
316  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
2.1  

Downstream Synthesis Route

[1]Das,Jagabandhu;Chen,Ping;Norris,Derek;Padmanabha,Ramesh;Lin,James;Moquin,RobertV.;Shen,Zhongqi;Cook,LyndaS.;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;McIntyre,KimW.;Shuster,DavidJ.;Gillooly,KathleenM.;Behnia,Kamelia;Schieven,GaryL.;Wityak,John;Barrish,JoelC.[JournalofMedicinalChemistry,2006,vol.49,#23,p.6819-6832]

[2]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-US2004/54186,2004,A1Locationinpatent:Page20

[3]Rajan,Remya;Schepmann,Dirk;Schreiber,JulianA.;Seebohm,Guiscard;Wünsch,Bernhard[EuropeanJournalofMedicinalChemistry,2021,vol.209]

[4]Nguyen,DoanH.;Szewczyk,JasonW.;Baird,EldonE.;Dervan,PeterB.[BioorganicandMedicinalChemistry,2001,vol.9,#1,p.7-17]

[5]Wityak,John;Das,Jagabandhu;Moquin,RobertV.;Shen,Zhongqi;Lin,James;Chen,Ping;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;Schieven,GaryL.;Kanner,StevenB.;Barrish,JoelC.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#22,p.4007-4010]

[6]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-WO2007/48771,2007,A1Locationinpatent:Page/Pagecolumn52

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-US2004/54186,2004,A1Locationinpatent:Page20

[2]Wityak,John;Das,Jagabandhu;Moquin,RobertV.;Shen,Zhongqi;Lin,James;Chen,Ping;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;Schieven,GaryL.;Kanner,StevenB.;Barrish,JoelC.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#22,p.4007-4010]

[3]Das,Jagabandhu;Chen,Ping;Norris,Derek;Padmanabha,Ramesh;Lin,James;Moquin,RobertV.;Shen,Zhongqi;Cook,LyndaS.;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;McIntyre,KimW.;Shuster,DavidJ.;Gillooly,KathleenM.;Behnia,Kamelia;Schieven,GaryL.;Wityak,John;Barrish,JoelC.[JournalofMedicinalChemistry,2006,vol.49,#23,p.6819-6832]

[1]Das,Jagabandhu;Chen,Ping;Norris,Derek;Padmanabha,Ramesh;Lin,James;Moquin,RobertV.;Shen,Zhongqi;Cook,LyndaS.;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;McIntyre,KimW.;Shuster,DavidJ.;Gillooly,KathleenM.;Behnia,Kamelia;Schieven,GaryL.;Wityak,John;Barrish,JoelC.[JournalofMedicinalChemistry,2006,vol.49,#23,p.6819-6832]

[2]Wityak,John;Das,Jagabandhu;Moquin,RobertV.;Shen,Zhongqi;Lin,James;Chen,Ping;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;Schieven,GaryL.;Kanner,StevenB.;Barrish,JoelC.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#22,p.4007-4010]

[3]Nguyen,DoanH.;Szewczyk,JasonW.;Baird,EldonE.;Dervan,PeterB.[BioorganicandMedicinalChemistry,2001,vol.9,#1,p.7-17]

[4]Rajan,Remya;Schepmann,Dirk;Schreiber,JulianA.;Seebohm,Guiscard;Wünsch,Bernhard[EuropeanJournalofMedicinalChemistry,2021,vol.209]

[1]Das,Jagabandhu;Chen,Ping;Norris,Derek;Padmanabha,Ramesh;Lin,James;Moquin,RobertV.;Shen,Zhongqi;Cook,LyndaS.;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;McIntyre,KimW.;Shuster,DavidJ.;Gillooly,KathleenM.;Behnia,Kamelia;Schieven,GaryL.;Wityak,John;Barrish,JoelC.[JournalofMedicinalChemistry,2006,vol.49,#23,p.6819-6832]

[2]Wityak,John;Das,Jagabandhu;Moquin,RobertV.;Shen,Zhongqi;Lin,James;Chen,Ping;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;Schieven,GaryL.;Kanner,StevenB.;Barrish,JoelC.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#22,p.4007-4010]

[3]Nguyen,DoanH.;Szewczyk,JasonW.;Baird,EldonE.;Dervan,PeterB.[BioorganicandMedicinalChemistry,2001,vol.9,#1,p.7-17]

[1]Das,Jagabandhu;Chen,Ping;Norris,Derek;Padmanabha,Ramesh;Lin,James;Moquin,RobertV.;Shen,Zhongqi;Cook,LyndaS.;Doweyko,ArthurM.;Pitt,Sidney;Pang,Suhong;Shen,DingRen;Fang,Qiong;DeFex,HenryF.;McIntyre,KimW.;Shuster,DavidJ.;Gillooly,KathleenM.;Behnia,Kamelia;Schieven,GaryL.;Wityak,John;Barrish,JoelC.[JournalofMedicinalChemistry,2006,vol.49,#23,p.6819-6832]

Literature
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Tags:302963-94-6 Molecular Formula|302963-94-6 MDL|302963-94-6 SMILES|302963-94-6 N-Boc-amino-4-methylthiazole-5-carboxylic acid