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30299-08-2,MFCD00865769
Catalog No.:AA002ZGX

30299-08-2 | Clinofibrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$6.00   $4.00
- +
5mg
97%
in stock  
$7.00   $5.00
- +
10mg
97%
in stock  
$9.00   $7.00
- +
50mg
97%
in stock  
$12.00   $8.00
- +
1g
97%
in stock  
$211.00   $148.00
- +
5g
97%
in stock  
$610.00   $427.00
- +
10g
97%
in stock  
$1,009.00   $706.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002ZGX
Chemical Name:
Clinofibrate
CAS Number:
30299-08-2
Molecular Formula:
C28H36O6
Molecular Weight:
468.5818
MDL Number:
MFCD00865769
SMILES:
CCC(C(=O)O)(Oc1ccc(cc1)C1(CCCCC1)c1ccc(cc1)OC(C(=O)O)(CC)C)C
Properties
Properties
 
BP:
613.8°C at 760 mmHg  
Form:
Solid  
MP:
143-145°C  
Refractive Index:
1.4482 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
633  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
Undefined Atom Stereocenter Count:
2  
XLogP3:
7.5  

Literature

Title: In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: 4,4'-(Cyclo-hexane-1,1-di-yl)diphenol methanol solvate.

Journal: Acta crystallographica. Section E, Structure reports online 20090201

Title: Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts.

Journal: Clinical and experimental pharmacology & physiology 20070901

Title: A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin.

Journal: The Tokai journal of experimental and clinical medicine 20050901

Title: [Usefulness of examination of the cholesterol versus triglyceride ratio for lipoprotein fractions in a patient with marked hyper-triglyceridemia].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20021001

Title: Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

Journal: Biochemical and biophysical research communications 20020111

Title: Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate.

Journal: Journal of pharmacobio-dynamics 19870301

Title: Okazaki M, et al. Effects of clinofibrate on plasma fibrinogen level in high fructose diet-induced hyperlipidemic rats. In Vivo. 1994 Nov-Dec;8(6):1057-61.

Title: Shirai K, et al. Effect of clinofibrate on lipid metabolism of aorta in atherosclerotic rats. Artery. 1983;12(3):145-55.

Title: Suzuki K, et al. Effects of S-8527 (1,1-bis4'-(1"-carboxy'1"-methylpropoxy)-phenyl)-cyclohexane), a new hypolipidemic compound, on triglyceride metablolism in rats. Biochem Pharmacol. 1975 Jun 15;24(11-12):1203-7.

Title: Suzuki K, et al. Hypolipidemic effect of a new aryloxy compound, S-8527, in experimental animals. Jpn J Pharmacol. 1974 Jun;24(3):407-14.

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SDS
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