Home Deuterated Building Blocks 3040-44-6
3040-44-6,MFCD00006512
Catalog No.:AA002ZY4

3040-44-6 | 1-(2-Hydroxyethyl)piperidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10g
98%
in stock  
$9.00   $6.00
- +
25g
98%
in stock  
$15.00   $10.00
- +
500g
98%
in stock  
$83.00   $58.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002ZY4
Chemical Name:
1-(2-Hydroxyethyl)piperidine
CAS Number:
3040-44-6
Molecular Formula:
C7H15NO
Molecular Weight:
129.2001
MDL Number:
MFCD00006512
SMILES:
OCCN1CCCCC1
NSC Number:
3460
Properties
Properties
 
BP:
200.5°C at 760 mmHg  
Form:
Liquid  
MP:
16 °C  
Refractive Index:
n20/D 1.4804(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
69.3  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1  

Upstream Synthesis Route

[1]OrganicLetters,2013,vol.15,#12,p.2930-2933

[1]CollectionofCzechoslovakChemicalCommunications,1989,vol.54,#7,p.1846-1853

[1]Patent:CN105884699,2016,A,.Locationinpatent:Paragraph0048;0049

[2]Patent:US2006/223855,2006,A1,.Locationinpatent:Page/Pagecolumn160-161

[3]JournalofPolymerScience,PartA:PolymerChemistry,2014,vol.52,#5,p.671-679

[1]ChemicalCommunications,2016,vol.52,#61,p.9526-9529

[2]JournaloftheIndianChemicalSociety,1987,vol.64,#5,p.316-318

[3]AustralianJournalofChemistry,2007,vol.60,#4,p.236-242

Downstream Synthesis Route

[1]CurrentPatentAssignee:EVOTECAG-WO2009/121812,2009,A1Locationinpatent:Page/Pagecolumn71

[2]Daoud;Ibrahim;Saeed[JournaloftheIndianChemicalSociety,1989,vol.66,#5,p.316-318]

[3]CurrentPatentAssignee:BARRYUNIVERSITY;BARRYUNIV-WO2014/14698,2014,A2Locationinpatent:Paragraph0064;0074

[4]Boulos,JohnF.;Jakubik,Jan;Boulos,JohnM.;Randakova,Alena;Momirov,Jelena[ChemicalBiologyandDrugDesign,2018,vol.91,#1,p.93-104]

[5]Leonard;Simet[JournaloftheAmericanChemicalSociety,1955,vol.77,p.2855,2857]

[6]CurrentPatentAssignee:BEIJINGADAMADLEBIOTECHNOLOGYLIABILITY-CN108707139,2018,ALocationinpatent:Paragraph0514;0515;0516;0517

[7]CurrentPatentAssignee:SICHUANUNIVERSITY-CN112851599,2021,ALocationinpatent:Paragraph0097-0100

[8]CurrentPatentAssignee:SICHUANUNIVERSITY-CN112939896,2021,ALocationinpatent:Paragraph0080-0083

3040-44-6    1202-25-1   
4-dimethylamino-benzoicacid-(2-piperidino-ethylester) 

[1]Patent:DE172568,

[1]Locationinpatent:experimentalpartGamzaeva;Mamedova,P.Sh.;Allakhverdieva;Velieva,G.Kh.;Akhundova;Allakhverdiev[RussianJournalofAppliedChemistry,2009,vol.82,#9,p.1577-1581]

[2]CurrentPatentAssignee:HETERODRUGSLIMITED-WO2018/29604,2018,A1Locationinpatent:Page/Pagecolumn63;64

[3]Knorr;Hoerlein;Roth[ChemischeBerichte,1905,vol.38,p.3138]

[4]Gilman;Woods[JournaloftheAmericanChemicalSociety,1945,vol.67,p.1843]Dupreetal.[JournaloftheChemicalSociety,1949,p.500,505]Bany[ActaPoloniaePharmaceutica,1955,vol.12,p.223,229][Chem.Abstr.,1956,p.12042]CurrentPatentAssignee:SYMRISEAG-DE881655,1949,C[DRP/DRBPOrg.Chem.][DRP/DRBPOrg.Chem.]Kuriharaetal.[TohokuYakkaDaigakuKiyo,1955,#2,p.42,44][Chem.Abstr.,1956,p.10688]Pratesi[Annalidichimicafarmaceutica,1938(Dez.)63,66]

[5]Gilman;Woods[JournaloftheAmericanChemicalSociety,1945,vol.67,p.1843]Dupreetal.[JournaloftheChemicalSociety,1949,p.500,505]Bany[ActaPoloniaePharmaceutica,1955,vol.12,p.223,229][Chem.Abstr.,1956,p.12042]CurrentPatentAssignee:SYMRISEAG-DE881655,1949,C[DRP/DRBPOrg.Chem.][DRP/DRBPOrg.Chem.]Kuriharaetal.[TohokuYakkaDaigakuKiyo,1955,#2,p.42,44][Chem.Abstr.,1956,p.10688]Pratesi[Annalidichimicafarmaceutica,1938(Dez.)63,66]

[6]Affini,Anna;Hagenow,Stefanie;Zivkovic,Aleksandra;Marco-Contelles,Jose;Stark,Holger[EuropeanJournalofMedicinalChemistry,2018,vol.148,p.487-497]

[7]CurrentPatentAssignee:PFIZERINC-WO2005/108359,2005,A1Locationinpatent:Page/Pagecolumn60

[1]CurrentPatentAssignee:CHINESEACADEMYOFSCIENCES-CN110357923,2019,ALocationinpatent:Paragraph0301-0303;0306

[2]Dubey,Abhishek;Khaskin,Eugene[ACSCatalysis,2016,vol.6,#6,p.3998-4002]

[3]Adkins;Pavlic[JournaloftheAmericanChemicalSociety,1947,vol.69,p.3039]Adkins;Billica[JournaloftheAmericanChemicalSociety,1948,vol.70,p.3121]

Literature

Title: Toward rational design of amine solutions for PCC applications: the kinetics of the reaction of CO2(aq) with cyclic and secondary amines in aqueous solution.

Journal: Environmental science & technology 20120703

Title: Cytotoxic activity and DNA-binding properties of xanthone derivatives.

Journal: Journal of fluorescence 20101101

Title: In vitro cytotoxicity of benzopyranone derivatives with basic side chain against human lung cell lines.

Journal: Anticancer research 20101101

Title: The enhancing effect of ion-pairing on the skin permeation of glipizide.

Journal: AAPS PharmSciTech 20090901

Title: [Study on UV-Vis absorption spectra and fluorescence emission spectra of sixteen tetra-substituted metallophthalocyanine complexes].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20090501

Title: Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity.

Journal: Bioorganic & medicinal chemistry letters 20090101

Title: Synthesis of an optically pure synthetic intermediate of aloperine from a yeast-reductive product.

Journal: Bioscience, biotechnology, and biochemistry 20050801

Title: Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands.

Journal: Journal of medicinal chemistry 20050127

Title: Studies toward labeling cytisine with [11C]phosgene: rapid synthesis of a delta-lactam involving a new chemoselective lithiation-annulation method.

Journal: The Journal of organic chemistry 20040528

Title: Stereospecific rearrangements during the synthesis of pyrrolidines and related heterocycles from cyclizations of amino alcohols with vinyl Sulfones.

Journal: The Journal of organic chemistry 20031128

Title: Synthesis of sparteine-like chiral diamines and evaluation in the enantioselective lithiation-substitution of N-(tert-butoxycarbonyl)pyrrolidine.

Journal: Organic & biomolecular chemistry 20031121

Title: N-hydroxyethyl-piperidine and -pyrrolidine homoazasugars: preparation and evaluation of glycosidase inhibitory activity.

Journal: Bioorganic & medicinal chemistry 20030731

Title: Indolizino[1,2-b]quinolines derived from A-D rings of camptothecin: synthesis and DNA interaction.

Journal: Journal of enzyme inhibition and medicinal chemistry 20030401

Title: Formaldehyde-induced DNA cross-link of indolizino[1,2-b]quinolines derived from the A-D rings of camptothecin.

Journal: Journal of medicinal chemistry 20021219

Title: Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20010101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:3040-44-6 Molecular Formula|3040-44-6 MDL|3040-44-6 SMILES|3040-44-6 1-(2-Hydroxyethyl)piperidine |Organic_Building_Blocks