Home Amines 30433-91-1
30433-91-1,MFCD00051495
Catalog No.:AA003018

30433-91-1 | Thiophene-2-ethylamine

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Purity
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Price(USD)
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5g
98%
in stock  
$6.00   $4.00
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25g
98%
in stock  
$16.00   $11.00
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100g
98%
in stock  
$62.00   $43.00
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500g
98%
in stock  
$220.00   $154.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Application
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003018
Chemical Name:
Thiophene-2-ethylamine
CAS Number:
30433-91-1
Molecular Formula:
C6H9NS
Molecular Weight:
127.2074
MDL Number:
MFCD00051495
SMILES:
NCCc1cccs1
Properties
Properties
 
BP:
199.7°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.551(lit.)  
Stability:
Air Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
65.5  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1  

Upstream Synthesis Route

[1]Patent:EP522956,1993,A2,

[1]IndianJournalofHeterocyclicChemistry,2010,vol.20,#2,p.197-198

[1]Patent:WO2012/1486,2012,A1,.Locationinpatent:Page/Pagecolumn18

[2]JournalofOrganicChemistry,2015,vol.80,#14,p.7019-7032

[3]Patent:EP1772455,2007,A2,.Locationinpatent:Page/Pagecolumn9

[4]JournalofOrganometallicChemistry,2009,vol.694,#13,p.2092-2095

[5]Patent:US2004/24011,2004,A1,.Locationinpatent:Page7

[6]SynthesisandReactivityinInorganic,Metal-OrganicandNano-MetalChemistry,2016,vol.46,#10,p.1552-1557

[1]Patent:WO2012/1486,2012,A1,

[1]OrganicandBiomolecularChemistry,2016,vol.14,#27,p.6398-6402

[2]Patent:WO2016/205534,2016,A1,

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartSaavedra,JaimeZ.;Resendez,Angel;Rovira,Alexander;Eagon,Scott;Haddenham,Dustin;Singaram,Bakthan[JournalofOrganicChemistry,2012,vol.77,#1,p.221-228]

[2]Abdel-Fattah,MohamedA.O.;Abadi,AshrafH.;Lehmann,Jochen;Schweikert,PeterM.;Enzensperger,Christoph[MedChemComm,2015,vol.6,#9,p.1679-1686]

[3]Frejd,Torbjoern;Klingstedt,Tomas[Synthesis,1987,#1,p.40-42]

[4]Blicke;Burckhalter[JournaloftheAmericanChemicalSociety,1942,vol.64,p.477,479]

[5]Herz;Tsai[JournaloftheAmericanChemicalSociety,1955,vol.77,p.3529,3531]Herz[JournaloftheAmericanChemicalSociety,1951,vol.73,p.351]Crowe;Nord[JournalofOrganicChemistry,1950,vol.15,p.81,87]

[6]Vecchietti;Clarke;Colle;Giardina;Petrone;Sbacchi[JournalofMedicinalChemistry,1991,vol.34,#8,p.2624-2633]

[7]Sehajpal,Pallvi;Kirar,Seema;Ghosh,Saptarshi;Banerjee,UttamChand[EnzymeandMicrobialTechnology,2018,vol.118,p.83-91]

[8]Weber,Stefan;Stöger,Berthold;Kirchner,Karl[OrganicLetters,2018,vol.20,#22,p.7212-7215]

[1]CurrentPatentAssignee:MEMORIALSLOAN-KETTERINGCANCERCENTER-WO2017/218874,2017,A1Locationinpatent:Paragraph00272

[2]CurrentPatentAssignee:INDUSTRIALTECHNOLOGYRESEARCHINSTITUTE-TWI526448,2016,BLocationinpatent:Paragraph0029

[3]CurrentPatentAssignee:INDUSTRIALTECHNOLOGYRESEARCHINSTITUTE-TWI594999,2017,BLocationinpatent:Paragraph0028

[4]Bremner,JohnB.;Browne,ElaineJ.;Davies,PeterE.[AustralianJournalofChemistry,1980,vol.33,#6,p.1335-1343]

[5]Herz[JournaloftheAmericanChemicalSociety,1951,vol.73,p.351]

[6]Locationinpatent:experimentalpartTamayo,NuriaA.;Bo,Yunxin;Gore,Vijay;Ma,Vu;Nishimura,Nobuko;Tang,Phi;Deng,Hong;Klionsky,Lana;Lehto,SonyaG.;Wang,Weiya;Youngblood,Brad;Chen,Jiyun;Correll,TiffanyL.;Bartberger,MichaelD.;Gavva,NarenderR.;Norman,MarkH.[JournalofMedicinalChemistry,2012,vol.55,#4,p.1593-1611]

2-(2-nitroethenyl)thiophene 
  30433-91-1 

[1]CurrentPatentAssignee:ShanghaiInstituteofMateriaMedica(in:CAS);CHINESEACADEMYOFSCIENCES-EP2848617,2015,A1Locationinpatent:Paragraph0055;0056

[2]CurrentPatentAssignee:ShanghaiInstituteofMateriaMedica(in:CAS);CHINESEACADEMYOFSCIENCES-US2015/141419,2015,A1Locationinpatent:Paragraph0115;0116

[3]CurrentPatentAssignee:CHINESEACADEMYOFSCIENCES;ShanghaiInstituteofMateriaMedica(in:CAS)-CN107303298,2017,ALocationinpatent:Paragraph0110;0111

[4]Meth-Cohn,Otto;Vij,RupRani;Smalley,RobertK.;Bass,RobertJ.[JournalofChemicalResearch,Miniprint,1989,#5,p.1001-1018]

[5]Gilsdorf;Nord[JournalofOrganicChemistry,1950,vol.15,p.807,810]

[6]Nguyen,Thuy;Gamage,ThomasF.;Decker,AnnM.;Finlay,DavidB.;Langston,TiffanyL.;Barrus,Daniel;Glass,Michelle;Harris,DanniL.;Zhang,Yanan[BioorganicandMedicinalChemistry,2021,vol.41]

[1]BioorganicandMedicinalChemistry,2000,vol.8,p.2277-2289

[1]CurrentPatentAssignee:CGENETECHSUZHOUCHINA-CN110204537,2019,ALocationinpatent:Paragraph0113-0114;0119-0120

[2]Malanga,Corrado;Mannucci,Serena;Lardicci,Luciano[JournalofChemicalResearch,Miniprint,2000,#6,p.701-715]

Literature
Application
2-Thiopheneethylamine, also known as 2-(thien-2-yl)ethylamine, is utilized to functionalize multiwall carbon nanotubes (MWCNT). Additionally, it serves as a reactant in the synthesis of pyrimidine derivatives by reacting with various isothiocyanatoketones and acylguanidines derivatives by reacting with aroyl S-methylisothiourea. This compound's versatility makes it valuable in materials science for modifying carbon nanotubes and in organic synthesis for accessing diverse heterocyclic compounds.
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Tags:30433-91-1 Molecular Formula|30433-91-1 MDL|30433-91-1 SMILES|30433-91-1 Thiophene-2-ethylamine |Organic_Building_Blocks