Title: Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential.
Journal: The international journal of neuropsychopharmacology20150401
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal20130415
Title: Proteinase-activated receptor 2 (PAR(2)) in cholangiocarcinoma (CCA) cells: effects on signaling and cellular level.
Journal: Histochemistry and cell biology20121201
Title: Curcumin produces antidepressant effects via activating MAPK/ERK-dependent brain-derived neurotrophic factor expression in the amygdala of mice.
Journal: Behavioural brain research20121101
Title: Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase.
Journal: The Journal of pharmacology and experimental therapeutics20120901
Title: Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.
Journal: Journal of neurochemistry20120501
Title: The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.
Journal: Breast cancer research and treatment20120101
Title: Mitogen-activated protein kinase in the amygdala plays a critical role in lithium chloride-induced taste aversion learning.
Journal: Neurobiology of learning and memory20120101
Title: MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis.
Journal: Stem cells (Dayton, Ohio)20111201
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology20111101
Title: The MEK inhibitor SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion: a behavioral and immunohistochemical study.
Journal: Psychopharmacology20110701
Title: Naloxone-precipitated morphine withdrawal evokes phosphorylation of heat shock protein 27 in rat heart through extracellular signal-regulated kinase.
Journal: Journal of molecular and cellular cardiology20110701
Title: Inhibition of extracellular signal-regulated kinase (ERK) activity with SL327 does not prevent acquisition, expression, and extinction of ethanol-seeking behavior in mice.
Journal: Behavioural brain research20110301
Title: Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20101215
Title: Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
Journal: Stem cells (Dayton, Ohio)20101101
Title: Oral supplementation with Leu-Ile, a hydrophobic dipeptide, prevents the impairment of memory induced by amyloid beta in mice via restraining the hyperphosphorylation of extracellular signal-regulated kinase.
Journal: Behavioural brain research20100711
Title: Intrastriatal inhibition of extracellular signal-regulated kinases impaired the consolidation phase of motor skill learning.
Journal: Neurobiology of learning and memory20100701
Title: 5-HT1A receptors mediate detrimental effects of cocaine on long-term potentiation and expression of polysialylated neural cell adhesion molecule protein in rat dentate gyrus.
Journal: Neuroscience20100310
Title: Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures.
Journal: Journal of neurochemistry20100301
Title: Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.
Journal: Toxicology and applied pharmacology20100215
Title: Identification of plasticity-associated genes regulated by Pavlovian fear conditioning in the lateral amygdala.
Journal: Journal of neurochemistry20100201
Title: The time course of unconditioned morphine-induced psychomotor sensitization mirrors the phosphorylation of FADD and MEK/ERK in rat striatum: role of PEA-15 as a FADD-ERK binding partner in striatal plasticity.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20100101
Title: ERK1/2 activation in reactive astrocytes of mice with pilocarpine-induced status epilepticus.
Journal: Neurological research20091201
Title: Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment.
Journal: Journal of neuroscience research20091201
Title: Synergistic interactions of dopamine D1 and glutamate NMDA receptors in rat hippocampus and prefrontal cortex: involvement of ERK1/2 signaling.
Journal: Neuroscience20091110
Title: Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20091101
Title: Extracellular signal-regulated kinase activation is required for consolidation and reconsolidation of memory at an early stage of ontogenesis.
Journal: The European journal of neuroscience20091101
Title: Extracellular signal-regulated kinase activation in the amygdala mediates elevated plus maze behavior during opioid withdrawal.
Journal: Behavioural pharmacology20091001
Title: Cross-talk between protein kinase A and mitogen-activated protein kinases signalling in the adaptive changes observed during morphine withdrawal in the heart.
Journal: The Journal of pharmacology and experimental therapeutics20090901
Title: Increased operant responding for ethanol in male C57BL/6J mice: specific regulation by the ERK1/2, but not JNK, MAP kinase pathway.
Journal: Psychopharmacology20090501
Title: Effects of the MEK inhibitor, SL-327, on rewarding, motor- and cellular-activating effects of D-amphetamine and SKF-82958, and their augmentation by food restriction in rat.
Journal: Psychopharmacology20090101
Title: ERK signalling pathway is not involved in PSA-NCAM-dependent alterations of hippocampal plasticity evoked by CB1 receptor activation.
Journal: Pharmacological reports : PR20090101
Title: IL-6 mediated alterations on immobile behavior of rats in the forced swim test via ERK1/2 activation in specific brain regions.
Journal: Behavioural brain research20081121
Title: Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization.
Journal: The Journal of comparative neurology20081110
Title: Regulation of extracellular signal-regulated kinases (ERKs) by naloxone-induced morphine withdrawal in the brain stress system.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20081001
Title: The PKs PKA and ERK 1/2 are involved in phosphorylation of TH at Serine 40 and 31 during morphine withdrawal in rat hearts.
Journal: British journal of pharmacology20080901
Title: Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20080827
Title: Involvement of extracellular signal-regulated protein kinase in acute cocaine-induced c-fos in nucleus accumbens.
Journal: Neuroscience letters20080620
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America20071218
Title: Extracellular signal-regulated kinase (ERK) inhibition does not prevent the development or expression of tolerance to and dependence on morphine in the mouse.
Journal: Pharmacology, biochemistry, and behavior20071101
Title: Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation.
Journal: Journal of neurochemistry20071001
Title: Extracellular signal-regulated kinase 1/2 involvement in the enhancement of contextual fear conditioning by nicotine.
Journal: Behavioral neuroscience20071001
Title: Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070926
Title: Cellular mechanisms underlying the anxiolytic effect of low doses of peripheral Delta9-tetrahydrocannabinol in rats.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20070901
Title: Activation of the ERK signalling pathway contributes to the adaptive changes in rat hearts during naloxone-induced morphine withdrawal.
Journal: British journal of pharmacology20070701
Title: Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070627
Title: The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala.
Journal: Biological psychiatry20070501
Title: A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment.
Journal: Biological psychiatry20070301
Title: Rnd family genes are differentially regulated by 3,4-methylenedioxymethamphetamine and cocaine acute treatment in mice brain.
Journal: Brain research20070223
Title: A role for ERK2 in reconsolidation of fear memories in mice.
Journal: Neurobiology of learning and memory20060901
Title: Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation.
Journal: Neuropharmacology20060401
Title: Inhibition of ERK pathway or protein synthesis during reexposure to drugs of abuse erases previously learned place preference.
Journal: Proceedings of the National Academy of Sciences of the United States of America20060221
Title: Regulation of cocaine-induced activator protein 1 transcription factors by the extracellular signal-regulated kinase pathway.
Journal: Neuroscience20060101
Title: Extracellular signal-regulated mitogen-activated protein kinase inhibitors decrease amphetamine-induced behavior and neuropeptide gene expression in the striatum.
Journal: Neuroscience20060101
Title: Role of the ERK pathway in psychostimulant-induced locomotor sensitization.
Journal: BMC neuroscience20060101
Title: Parsing molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20051207
Title: Extracellular signal-regulated kinases (ERKs) modulate cocaine-induced gene expression in the mouse amygdala.
Journal: The European journal of neuroscience20050801
Title: Odorant-induced activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in the olfactory bulb promotes survival of newly formed granule cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050601
Title: Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects.
Journal: Journal of neurochemistry20050501
Title: ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation.
Journal: The Journal of biological chemistry20050211
Title: Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor stimulation in rats.
Journal: Neuroscience20050101
Title: Inhibition of mitogen-activated protein kinase-extracellular signal-regulated kinase disrupts latent inhibition of cued fear conditioning in C57BL/6 mice.
Journal: Behavioral neuroscience20041201
Title: Amphetamine-evoked gene expression in striatopallidal neurons: regulation by corticostriatal afferents and the ERK/MAPK signaling cascade.
Journal: Journal of neurochemistry20041001
Title: Sustained extracellular signal-regulated kinase 1/2 phosphorylation in neonate 6-hydroxydopamine-lesioned rats after repeated D1-dopamine receptor agonist administration: implications for NMDA receptor involvement.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20040630
Title: Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20040331
Title: The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030813
Title: Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum.
Journal: Journal of neurochemistry20030701
Title: Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030315
Title: Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis.
Journal: The Journal of pharmacology and experimental therapeutics20030101
Title: A role for ERK MAP kinase in physiologic temporal integration in hippocampal area CA1.
Journal: Learning & memory (Cold Spring Harbor, N.Y.)20030101
Title: Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms.
Journal: The Journal of pharmacology and experimental therapeutics20020801
Title: The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures.
Journal: Journal of neurochemistry20020701
Title: Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo.
Journal: Journal of neurochemistry20020301
Title: Differential regulation of IL-1beta and TNF-alpha RNA expression by MEK1 inhibitor after focal cerebral ischemia in mice.
Journal: Biochemical and biophysical research communications20010907
Title: Delta 9-tetrahydrocannabinol-induced MAPK/ERK and Elk-1 activation in vivo depends on dopaminergic transmission.
Journal: The European journal of neuroscience20010701
Title: Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Journal: Blood20010401
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