Home Amines 30544-47-9
30544-47-9,MFCD00242806
Catalog No.:AA0030FM

30544-47-9 | 2-(2-hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate

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25mg
98%
in stock  
$113.00   $79.00
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50mg
≥98%
in stock  
$128.00   $89.00
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100mg
≥98%
in stock  
$202.00   $141.00
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250mg
≥98%
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$378.00   $264.00
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500mg
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$688.00   $481.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0030FM
Chemical Name:
2-(2-hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate
CAS Number:
30544-47-9
Molecular Formula:
C18H18F3NO4
Molecular Weight:
369.3350
MDL Number:
MFCD00242806
SMILES:
OCCOCCOC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F
Properties
Computed Properties
 
Complexity:
433  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  
XLogP3:
4.7  

Downstream Synthesis Route

[1]Boltze;Kreisfeld[Arzneimittel-Forschung/DrugResearch,1977,vol.27,#6b,p.1300-1312]

[1]Boltze;Kreisfeld[Arzneimittel-Forschung/DrugResearch,1977,vol.27,#6b,p.1300-1312]

628-89-7   
Potassium;2-(3-trifluoromethyl-phenylamino)-benzoate 
  30544-47-9 

[1]Boltze;Kreisfeld[Arzneimittel-Forschung/DrugResearch,1977,vol.27,#6b,p.1300-1312]

Potassium;2-(3-trifluoromethyl-phenylamino)-benzoate 
  30544-47-9 

[1]Boltze;Kreisfeld[Arzneimittel-Forschung/DrugResearch,1977,vol.27,#6b,p.1300-1312]

Literature

Title: Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant.

Journal: Environmental science and pollution research international 20120601

Title: A European multicentre photopatch test study.

Journal: The British journal of dermatology 20120501

Title: Action spectrum for etofenamate photoallergic contact dermatitis.

Journal: Contact dermatitis 20110801

Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

Journal: Healthcare informatics research 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Etofenamate associated with Lyell syndrome: a case report.

Journal: Clinical toxicology (Philadelphia, Pa.) 20100601

Title: Pharmacokinetic profile of an intradeltoid diclofenac injection in obese Indian volunteers.

Journal: Journal of pain research 20100101

Title: Influence of preemptive analgesia on pulmonary function and complications for laparoscopic cholecystectomy.

Journal: Digestive diseases and sciences 20091201

Title: Anti-inflammatory effects of locally applied enzyme-loaded ultradeformable vesicles on an acute cutaneous model.

Journal: Journal of microencapsulation 20091101

Title: Allergic and photoallergic contact dermartitis from etofenamate: study of 14 cases.

Journal: Contact dermatitis 20090801

Title: Efficacy of epicutaneous Diractin (ketoprofen in Transfersome gel) for the treatment of pain related to eccentric muscle contractions.

Journal: Drug design, development and therapy 20090101

Title: Allergic contact dermatitis to etofenamate. Cross-reaction to other nonsteroidal anti-inflammatory drugs.

Journal: Contact dermatitis 20080201

Title: Topical etofenamate to facilitate venipuncture.

Journal: Pediatric emergency care 20071001

Title: [Results and assessment of photopatch testing in Spain: towards a new standard set of photoallergens].

Journal: Actas dermo-sifiliograficas 20070301

Title: [Etofenamate and the analgesic effect in the management of acute pain from spine in the emergency room].

Journal: Acta ortopedica mexicana 20070101

Title: [Comparative clinical multicenter study to evaluate analgesic effectiveness of intramuscular etofenamate and diclofenac in patients with post-surgical pain].

Journal: Cirugia y cirujanos 20040101

Title: Allergic contact dermatitis from etofenamate without cross-sensitization to other anthranilic acid derivatives.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Intramuscular Etofenamate versus Diclofenac in the Relief of Renal Colic : A Randomised, Single-Blind, Comparative Study.

Journal: Clinical drug investigation 20030101

Title: Combined contact and photocontact allergic dermatitis to etofenamate in flogoprofen gel.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20011201

Title: Comparative study of etofenamate and fentanyl for outpatient extracorporeal shockwave lithotripsy.

Journal: Scandinavian journal of urology and nephrology 20011201

Title: Etofenamate levels in human serum and synovial fluid following iontophoresis.

Journal: Arzneimittel-Forschung 20010101

Title: Effects of some pharmacological agents on the survival of unipedicled venous flaps: an experimental study.

Journal: Microsurgery 20010101

Title: Bender T, Bariska J, Rojkovich B, Bálint G. Etofenamate levels in human serum and synovial fluid following iontophoresis. Arzneimittelforschung. 2001;51(6):489-92.

Title: Fraga A, de Almeida M, Moreira-da-Silva V et al. Intramuscular Etofenamate versus Diclofenac in the Relief of Renal Colic : A Randomised, Single-Blind, Comparative Study. Clin Drug Investig. 2003;23(11):701-6.

Title: Joana Marto, et al. Topical gels of etofenamate: in vitro and in vivo evaluation. Pharm Dev Technol. 2015;20(6):710-5.

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Tags:30544-47-9 Molecular Formula|30544-47-9 MDL|30544-47-9 SMILES|30544-47-9 2-(2-hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate