Home Nitro Compounds 70-25-7
70-25-7,MFCD00007034
Catalog No.:AA0032Q4

70-25-7 | 1-Methyl-3-nitro-1-nitrosoguanidine

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1g
95%
in stock  
$375.00   $263.00
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5g
95%
in stock  
$1,490.00   $1,043.00
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25g
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$6,495.00   $4,547.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0032Q4
Chemical Name:
1-Methyl-3-nitro-1-nitrosoguanidine
CAS Number:
70-25-7
Molecular Formula:
C2H5N5O3
Molecular Weight:
147.0928
MDL Number:
MFCD00007034
SMILES:
O=NN(C(=N)N[N+](=O)[O-])C
NSC Number:
9369
UN Number:
1325
Properties
Properties
 
Form:
Liquid  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
161  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
0.1  

Literature

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Journal: Toxicology 20150504

Title: Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150201

Title: miR-21 regulates N-methyl-N-nitro-N'-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2.

Journal: Toxicology letters 20140804

Title: The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140701

Title: Improvement of multiple stress tolerance in yeast strain by sequential mutagenesis for enhanced bioethanol production.

Journal: Journal of bioscience and bioengineering 20121201

Title: Novel method for screening Saccharomyces cerevisiae mutants with increased sulfur-containing compounds: color-based selection of ade1 or ade2 mutants.

Journal: Journal of bioscience and bioengineering 20121201

Title: A comparative study of the anticlastogenic effects of chlorophyllin on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or 7,12-dimethylbenz (α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo.

Journal: Toxicology letters 20121115

Title: Screening and characteristics of a butanol-tolerant strain and butanol production from enzymatic hydrolysate of NaOH-pretreated corn stover.

Journal: World journal of microbiology & biotechnology 20121001

Title: O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation.

Journal: Integrative biology : quantitative biosciences from nano to macro 20121001

Title: AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.

Journal: Cell death & disease 20120901

Title: Protective properties of five newly synthesized cyclic compounds against sodium azide and N-methyl-N'-nitro-N-nitrosoguanidine genotoxicity.

Journal: Toxicology and industrial health 20120801

Title: Rebamipide induces dendritic cell recruitment to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-exposed rat gastric mucosa based on IL-1β upregulation.

Journal: Biochemical and biophysical research communications 20120720

Title: Protective effect of ellagic acid (EA) on micronucleus formation induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in mammalian cells, in in vitro assays and in vivo.

Journal: Mutation research 20120704

Title: Antigenotoxic properties of two newly synthesized β-aminoketones against N-methyl-N'-nitro-N-nitrosoguanidine and 9-aminoacridine-induced mutagenesis.

Journal: Journal of biochemical and molecular toxicology 20120701

Title: Gene-TEQ--a standardized comparative assessment of effects in the comet assay using genotoxicity equivalents.

Journal: Journal of environmental monitoring : JEM 20120501

Title: A new insect cell line from pupal ovary of Spodoptera exigua established by stimulation with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Journal: In vitro cellular & developmental biology. Animal 20120501

Title: Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: The Journal of biological chemistry 20120413

Title: Usefulness of combined in vivo skin comet assay and in vivo skin micronucleus test.

Journal: Mutation research 20120318

Title: Genome-wide analysis of mutagenesis bias and context sensitivity of N-methyl-N'-nitro-N-nitrosoguanidine (NTG).

Journal: Mutation research 20120301

Title: Food borne yeasts as DNA-bioprotective agents against model genotoxins.

Journal: International journal of food microbiology 20120215

Title: Modulatory effect of phytoglycoprotein (38 kDa) on cyclin D1/CDK4 in BNL CL.2 cells induced by N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120201

Title: Promotion of hepatocarcinogenesis by perfluoroalkyl acids in rainbow trout.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101

Title: Detection of N-(hexanoyl)lysine in the tropomyosin 1 protein in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric cancer cells.

Journal: Journal of clinical biochemistry and nutrition 20120101

Title: A 40-50kDa Glycoprotein Associated with Mucus is Identified as α-1-Acid Glycoprotein in Carcinoma of the Stomach.

Journal: Journal of Cancer 20120101

Title: Xylem sap collection and extraction methodologies to determine in vivo concentrations of ABA and its bound forms by gas chromatography-mass spectrometry (GC-MS).

Journal: Plant methods 20120101

Title: Functional interaction between human papillomavirus type 16 E6 and E7 oncoproteins and cigarette smoke components in lung epithelial cells.

Journal: PloS one 20120101

Title: Isolation of mutants and construction of intersexual heterokaryons of Blakeslea trispora.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: The synergistic effect of chemical carcinogens enhances Epstein-Barr virus reactivation and tumor progression of nasopharyngeal carcinoma cells.

Journal: PloS one 20120101

Title: Use of the in vivo skin comet assay to evaluate the DNA-damaging potential of chemicals applied to the skin.

Journal: Mutation research 20111224

Title: ICAM-1 and AMPK regulate cell detachment and apoptosis by N-methyl-N'-nitro-N-nitrosoguanidine, a widely spread environmental chemical, in human hormone-refractory prostate cancers.

Journal: Toxicology and applied pharmacology 20111215

Title: Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis.

Journal: Molecular pharmacology 20111201

Title: Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse.

Journal: Environmental and molecular mutagenesis 20111201

Title: In vitro mutagen binding and antimutagenic activity of human Lactobacillus rhamnosus 231.

Journal: Anaerobe 20111001

Title: Antimutagenic effect of Phellinus rimosus (Berk) Pilat against chemical induced mutations of histidine dependent Salmonella typhimurium strains.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111001

Title: Sex-associated difference in estrogen receptor β expression in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancers in rats.

Journal: Comparative medicine 20111001

Title: Validation of a genotoxicity test based on p53R2 gene expression in human lymphoblastoid cells.

Journal: Mutation research 20110918

Title: The Escherichia coli alkylation response protein AidB is a redox partner of flavodoxin and binds RNA and acyl carrier protein.

Journal: Archives of biochemistry and biophysics 20110915

Title: Quantitative and subcellular localization analysis of the nuclear isoform dUTP pyrophosphatase in alkylating agent-induced cell responses.

Journal: Toxicology 20110905

Title: Enhanced L-phenylalanine production by recombinant Escherichia coli BR-42 (pAP-B03) resistant to bacteriophage BP-1 via a two-stage feeding approach.

Journal: Journal of industrial microbiology & biotechnology 20110901

Title: An alkyltransferase-like protein from Thermus thermophilus HB8 affects the regulation of gene expression in alkylation response.

Journal: Journal of biochemistry 20110901

Title: N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) triggers MSH2 and Cdt2 protein-dependent degradation of the cell cycle and mismatch repair (MMR) inhibitor protein p21Waf1/Cip1.

Journal: The Journal of biological chemistry 20110826

Title: In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer.

Journal: Biochemical and biophysical research communications 20110812

Title: Involvement of mismatch repair proteins in adaptive responses induced by N-methyl-N'-nitro-N-nitrosoguanidine against γ-induced genotoxicity in human cells.

Journal: Mutation research 20110801

Title: Synergistic cytotoxicity of N-methyl-N'-nitro-N-nitrosoguanidine and absence of poly(ADP-ribose) glycohydrolase involves chromatin decondensation.

Journal: International journal of oncology 20110701

Title: α4 is highly expressed in carcinogen-transformed human cells and primary human cancers.

Journal: Oncogene 20110630

Title: The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage.

Journal: DNA repair 20110610

Title: Myenteric denervation downregulates galectin-1 and -3 expression in gastric carcinogenesis.

Journal: Digestive diseases and sciences 20110601

Title: Chemopreventive effect of epigallocatechin-3-gallate (EGCG) and folic acid on the N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal cancer in rat model.

Journal: Journal of digestive diseases 20110601

Title: Cyclin D1/cdk4, estrogen receptors α and β, in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric carcinogenesis: immunohistochemical study.

Journal: The Journal of toxicological sciences 20110601

Title: Application of the DNA adductome approach to assess the DNA-damaging capability of in vitro micronucleus test-positive compounds.

Journal: Mutation research 20110318

Title: Mutations that probe the cooperative assembly of O⁶-alkylguanine-DNA alkyltransferase complexes.

Journal: Biochemistry 20110315

Title: Antimutagenicity mechanisms of the Rhoeo discolor ethanolic extract.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110301

Title: Role of alkyltransferase-like (ATL) protein in repair of methylated DNA lesions in Thermus thermophilus.

Journal: Mutagenesis 20110301

Title: Astaxanthin biosynthesis is enhanced by high carotenogenic gene expression and decrease of fatty acids and ergosterol in a Phaffia rhodozyma mutant strain.

Journal: FEMS yeast research 20110301

Title: Improvement of fungal cellulase production by mutation and optimization of solid state fermentation.

Journal: Mycobiology 20110301

Title: Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG.

Journal: Investigational new drugs 20110201

Title: Deoxycytidine production by metabolically engineered Corynebacterium ammoniagenes.

Journal: Journal of microbiology (Seoul, Korea) 20110201

Title: Production of cellulases and xylanases under catabolic repression conditions from mutant PR-22 of Cellulomonas flavigena.

Journal: Journal of industrial microbiology & biotechnology 20110101

Title: DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer.

Journal: PloS one 20110101

Title: Cooperative nuclear localization sequences lend a novel role to the N-terminal region of MSH6.

Journal: PloS one 20110101

Title: Strain improvement for enhanced production of cellulase in Trichoderma viride.

Journal: Prikladnaia biokhimiia i mikrobiologiia 20110101

Title: The role of human papillomavirus in the pathogenesis of head & neck squamous cell carcinoma: an overview.

Journal: Infectious agents and cancer 20110101

Title: Latexin expression is downregulated in human gastric carcinomas and exhibits tumor suppressor potential.

Journal: BMC cancer 20110101

Title: Lycopene enhances antioxidant enzyme activities and immunity function in N-methyl-N'-nitro-N-nitrosoguanidine-enduced gastric cancer rats.

Journal: International journal of molecular sciences 20110101

Title: Loss of DNA mismatch repair imparts a selective advantage in planarian adult stem cells.

Journal: PloS one 20110101

Title: N-Nitrosamines (15 listings): N-Methyl-N'-Nitro-N-Nitrosoguanidine.

Journal: Report on carcinogens : carcinogen profiles 20110101

Title: Light and moderate doses of ethanol in chemical carcinogenesis of the colon in rats.

Journal: Nutrition and cancer 20110101

Title: Enhanced incorporation of 3-hydroxy-4-methylvalerate unit into biosynthetic polyhydroxyalkanoate using leucine as a precursor.

Journal: AMB Express 20110101

Title: Cumulative number of cell divisions as a meaningful timescale for adaptive laboratory evolution of Escherichia coli.

Journal: PloS one 20110101

Title: Enhancement of lutein production in Chlorella sorokiniana (Chorophyta) by improvement of culture conditions and random mutagenesis.

Journal: Marine drugs 20110101

Title: Protective effect of Lactobacillus rhamnosus 231 against N-Methyl-N'-nitro-N-nitrosoguanidine in animal model.

Journal: Gut microbes 20110101

Title: Cloning and functional analysis of the GSH1/MET1 gene complementing cysteine and glutathione auxotrophy of the methylotrophic yeast Hansenula polymorpha.

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

Title: Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.

Journal: The Journal of biological chemistry 20101224

Title: N-methyl-N'-nitro-N-nitrosoguanidine induces and cooperates with 12-O-tetradecanoylphorbol-1,3-acetate/sodium butyrate to enhance Epstein-Barr virus reactivation and genome instability in nasopharyngeal carcinoma cells.

Journal: Chemico-biological interactions 20101205

Title: Overexpression of CD151 as an adverse marker for intrahepatic cholangiocarcinoma patients.

Journal: Cancer 20101201

Title: Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.

Journal: Molecular pharmacology 20101101

Title: Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells.

Journal: Biochemical pharmacology 20101001

Title: Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

Journal: Journal of molecular biology 20100910

Title: Intestinal metaplasia -the effect of Acid on the gastric mucosa and gastric carcinogenesis-.

Journal: Journal of toxicologic pathology 20100901

Title: Enhanced DNA accessibility and increased DNA damage induced by the absence of poly(ADP-ribose) hydrolysis.

Journal: Biochemistry 20100831

Title: Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities.

Journal: The Journal of antibiotics 20100801

Title: Effects of DCA on Cell Cycle Proteins in Colonocytes.

Journal: Journal of the Korean Society of Coloproctology 20100801

Title: The role of PARP activation in glutamate-induced necroptosis in HT-22 cells.

Journal: Brain research 20100709

Title: Mutagenic and antimutagenic effects of hexane extract of some Astragalus species grown in the eastern Anatolia region of Turkey.

Journal: Phytotherapy research : PTR 20100701

Title: Radical mechanisms in nitrosamine- and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100701

Title: Enhanced tumorigenesis of forestomach tumors induced by N-Methyl-N'-nitro-N-nitrosoguanidine in rats with hypoinsulinemic diabetes.

Journal: Cancer science 20100701

Title: PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

Journal: Cancer research 20100701

Title: Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG.

Journal: Life sciences 20100619

Title: Enhanced l-phenylalanine biosynthesis by co-expression of pheA(fbr) and aroF(wt).

Journal: Bioresource technology 20100601

Title: Reduction of fatty acid flux results in enhancement of astaxanthin synthesis in a mutant strain of Phaffia rhodozyma.

Journal: Journal of industrial microbiology & biotechnology 20100601

Title: Early lesions induced in rat colon epithelium by N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Tissue & cell 20100601

Title: Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells.

Journal: Nutrition research and practice 20100601

Title: Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1.

Journal: DNA repair 20100504

Title: Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.

Journal: Life sciences 20100424

Title: Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition.

Journal: The Journal of biological chemistry 20100423

Title: RAD51D protects against MLH1-dependent cytotoxic responses to O(6)-methylguanine.

Journal: DNA repair 20100404

Title: Occurrence of anticancer activity of prednisolone via adrenalectomy and inhibition of adrenaline in rats.

Journal: International journal of cancer 20100401

Title: Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.

Journal: The Journal of biological chemistry 20100312

Title: Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.

Journal: Glia 20100301

Title: Comparison of gene expression profiles in BALB/c 3T3 transformed foci exposed to tumor promoting agents.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100301

Title: Vincristine attenuates N-methyl-N'-nitro-N-nitrosoguanidine-induced poly-(ADP) ribose polymerase activity in cardiomyocytes.

Journal: Journal of cardiovascular pharmacology 20100301

Title: Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.

Journal: The Journal of biological chemistry 20100219

Title: Antimutagenic effects of ethanolic extracts from selected Palestinian medicinal plants.

Journal: Journal of ethnopharmacology 20100203

Title: An in vitro micronucleus assay with size-classified micronucleus counting to discriminate aneugens from clastogens.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201

Title: Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles.

Journal: Cell cycle (Georgetown, Tex.) 20100101

Title: Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR).

Journal: PloS one 20100101

Title: Genomic features defining exonic variants that modulate splicing.

Journal: Genome biology 20100101

Title: Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Decreased transcription-coupled nucleotide excision repair capacity is associated with increased p53- and MLH1-independent apoptosis in response to cisplatin.

Journal: BMC cancer 20100101

Title: Isolation of an Escherichia coli K4 kfoC mutant over-producing capsular chondroitin.

Journal: Microbial cell factories 20100101

Title: Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia.

Journal: BMC gastroenterology 20100101

Title: Effects of myenteric denervation on extracellular matrix fibers and mast cell distribution in normal stomach and gastric lesions.

Journal: Cancer cell international 20100101

Title: Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism.

Journal: BMC biochemistry 20100101

Title: Genetic composition of laboratory stocks of the self-fertilizing fish Kryptolebias marmoratus: a valuable resource for experimental research.

Journal: PloS one 20100101

Title: Anti-mutagenic and anti-carcinogenic potential of the carotenoid meso-zeaxanthin.

Journal: Asian Pacific journal of cancer prevention : APJCP 20100101

Title: Response of human DNA polymerase ι promoter to N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Environmental toxicology and pharmacology 20100101

Title: Understanding the differences between genome sequences of Escherichia coli B strains REL606 and BL21(DE3) and comparison of the E. coli B and K-12 genomes.

Journal: Journal of molecular biology 20091211

Title: The aryl hydrocarbon receptor nuclear translocator (Arnt) is required for tumor initiation by benzo[a]pyrene.

Journal: Carcinogenesis 20091101

Title: MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Experimental cell research 20091101

Title: Interventional effect of Ginkgo biloba extract on the progression of gastric precancerous lesions in rats.

Journal: Journal of digestive diseases 20091101

Title: Increased riboflavin production from activated bleaching earth by a mutant strain of Ashbya gossypii.

Journal: Journal of bioscience and bioengineering 20091001

Title: C/EBPalpha expression is partially regulated by C/EBPbeta in response to DNA damage and C/EBPalpha-deficient fibroblasts display an impaired G1 checkpoint.

Journal: Oncogene 20090910

Title: Prolonged cell cycle response of HeLa cells to low-level alkylation exposure.

Journal: Cancer research 20090801

Title: AIF: not just an apoptosis-inducing factor.

Journal: Annals of the New York Academy of Sciences 20090801

Title: Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos).

Journal: Journal of neurochemistry 20090701

Title: Differential nuclear proteomes in response to N-methyl-N'-nitro-N-nitrosoguanidine exposure.

Journal: Journal of proteome research 20090601

Title: Genes responsible for dextran-dependent aggregation of Streptococcus sobrinus strain 6715.

Journal: Oral microbiology and immunology 20090601

Title: Isolation, characterization and long term preservation of mutant strains of Xanthophyllomyces dendrorhous.

Journal: Journal of basic microbiology 20090401

Title: Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090401

Title: Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage.

Journal: DNA repair 20090301

Title: Strain improvement of Acremonium cellulolyticus for cellulase production by mutation.

Journal: Journal of bioscience and bioengineering 20090301

Title: Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.

Journal: DNA repair 20090101

Title: Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Journal: BMC medical genomics 20090101

Title: Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients.

Journal: Journal of translational medicine 20090101

Title: Controversies surrounding human papilloma virus infection, head & neck vs oral cancer, implications for prophylaxis and treatment.

Journal: Head & neck oncology 20090101

Title: New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells.

Journal: BMC cancer 20090101

Title: Altered gene expression and miRNA expression associated with cancerous IEC-6 cell transformed by MNNG.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.

Journal: PloS one 20090101

Title: Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans.

Journal: PloS one 20090101

Title: Custom design and analysis of high-density oligonucleotide bacterial tiling microarrays.

Journal: PloS one 20090101

Title: Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation.

Journal: PloS one 20090101

Title: Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

Journal: PloS one 20090101

Title: Protective effects of garlic and silymarin on NDEA-induced rats hepatotoxicity.

Journal: International journal of biological sciences 20090101

Title: Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines.

Journal: PloS one 20090101

Title: Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B(12)-deficient rats.

Journal: Nutrition research and practice 20090101

Title: A color discriminating broad range cell staining technology for early detection of cell transformation.

Journal: Journal of carcinogenesis 20090101

Title: Endoscopic observation of N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rat using a newly-developed flexible endoscope.

Journal: Asian Pacific journal of cancer prevention : APJCP 20090101

Title: Kinetics of gamma-H2AX focus formation upon treatment of cells with UV light and alkylating agents.

Journal: Environmental and molecular mutagenesis 20081201

Title: Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death.

Journal: British journal of pharmacology 20081201

Title: Increased antimutagenic and anticlastogenic effects of doenjang (Korean fermented soybean paste) prepared with bamboo salt.

Journal: Journal of medicinal food 20081201

Title: Technical modification of the Balb/c 3T3 cell transformation assay: the use of serum-reduced medium to optimise the practicability of the protocol.

Journal: Alternatives to laboratory animals : ATLA 20081201

Title: Detection of micronucleated cells and gene expression changes in glandular stomach of mice treated with stomach-targeted carcinogens.

Journal: Mutation research 20081117

Title: Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression.

Journal: Oncology reports 20081101

Title: Association between fecal bile acids and colorectal cancer: a meta-analysis of observational studies.

Journal: Yonsei medical journal 20081031

Title: Modulatory effect of naringenin on N-methyl-N'-nitro-N-nitrosoguanidine- and saturated sodium chloride-induced gastric carcinogenesis in male Wistar rats.

Journal: Clinical and experimental pharmacology & physiology 20081001

Title: Combinatorial chemopreventive effect of Azadirachta indica and Ocimum sanctum on oxidant-antioxidant status, cell proliferation, apoptosis and angiogenesis in a rat forestomach carcinogenesis model.

Journal: Singapore medical journal 20081001

Title: Identification of early responsive genes in human amnion epithelial FL cells induced by N-methyl-N'-nitro-N-nitrosoguanidine using oligonucleotide microarray and quantitative real-time RT-PCR approaches.

Journal: Mutation research 20080926

Title: Histone H2AX is a critical factor for cellular protection against DNA alkylating agents.

Journal: Oncogene 20080925

Title: Nystatin interferes with the effects of N-methyl-N'-nitro-N-nitrosoguanidine on sphingolipid metabolism in human FL cells.

Journal: Lipids 20080901

Title: Antioxidative and antimutagenic activities of 70% ethanol extract from masou salmon (Oncorhynchus masou).

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080901

Title: Functional characteristics of Lactobacillus spp. from traditional Maasai fermented milk products in Kenya.

Journal: International journal of food microbiology 20080815

Title: DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.

Journal: The Journal of biological chemistry 20080801

Title: Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.

Journal: The Journal of biological chemistry 20080801

Title: Interplay of DNA repair pathways controls methylation damage toxicity in Saccharomyces cerevisiae.

Journal: Genetics 20080801

Title: Effects of Radix notoginseng extracts drug-containing serum on expressions of bcl-2, Bax and p21WAF1 proteins in MNNG transformed GES-1 cells.

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080801

Title: Raw milk traditional Italian ewe cheeses as a source of Lactobacillus casei strains with acid-bile resistance and antigenotoxic properties.

Journal: International journal of food microbiology 20080731

Title: Proteomic analysis of different temporal expression patterns induced by N-methyl-N'-nitro-N-nitrosoguanidine treatment.

Journal: Journal of proteome research 20080701

Title: [Preventive effects of 4 Se-enriched plants on rat stomach cancer induced by MNNG--3. Se accumulation and distribution in rats of different selenium resources for prevention of stomach cancer].

Journal: Wei sheng yan jiu = Journal of hygiene research 20080701

Title: [JWA regulates N-methyl-N'-nitro-N-nitrosoguanidine induced malignant transformation in human bronchial epithelial cells].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20080701

Title: [Establishment of Mongolian gerbil model of long-term Helicobacter pylori infection].

Journal: Zhonghua yi xue za zhi 20080610

Title: Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage.

Journal: Cancer biology & therapy 20080601

Title: Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment.

Journal: DNA repair 20080601

Title: Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma.

Journal: Experimental and molecular pathology 20080601

Title: Antimutagenic activity of a novel ascorbic derivative, disodium isostearyl 2-O-L-ascorbyl phosphate.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080601

Title: Suppressive effect of poly-gamma-glutamate on SOS response of Salmonella typhimurium induced by chemical mutagens.

Journal: Journal of bioscience and bioengineering 20080601

Title: In vitro effects of fluor-hydroxyapatite, fluorapatite and hydroxyapatite on colony formation, DNA damage and mutagenicity.

Journal: Mutation research 20080430

Title: BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations.

Journal: Cancer research 20080415

Title: Signaling of DNA damage is not sufficient to induce p53 response: (re)activation of wt p53 protein strongly depends on cellular context.

Journal: Journal of cellular biochemistry 20080401

Title: Mismatch repair in Trypanosoma brucei: heterologous expression of MSH2 from Trypanosoma cruzi provides new insights into the response to oxidative damage.

Journal: Gene 20080331

Title: A novel yeast-based tool to detect mutagenic and recombinogenic effects simultaneously.

Journal: Mutation research 20080329

Title: Differential expression of genes associated with cell proliferation and apoptosis induced by okadaic acid during the transformation process of BALB/c 3T3 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080201

Title: Genetic analysis of the Neurospora crassa RAD14 homolog mus-43 and the RAD10 homolog mus-44 reveals that they belong to the mus-38 pathway of two nucleotide excision repair systems.

Journal: Genes & genetic systems 20080201

Title: Characterization of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain.

Journal: Mutation research 20080108

Title: Evidence for in vitro anti-genotoxicity of cheese non-starter lactobacilli.

Journal: Antonie van Leeuwenhoek 20080101

Title: DNA mismatch repair-induced double-strand breaks.

Journal: DNA repair 20080101

Title: Neoplastic transformation and induction of H+,K+ -adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line.

Journal: In vitro cellular & developmental biology. Animal 20080101

Title: Preventive effect of fermented brown rice and rice bran on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.

Journal: Oncology reports 20080101

Title: Keratinase production and keratin degradation by a mutant strain of Bacillus subtilis.

Journal: Journal of Zhejiang University. Science. B 20080101

Title: Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron.

Journal: BMC gastroenterology 20080101

Title: Extract of radix curcumae prevents gastric cancer in rats.

Journal: Digestion 20080101

Title: [Preventive effects of 4 Se-enriched plants on rat stomach cancer induced by MNNG 2. Safety of different selenium resources for prevention of stomach cancer].

Journal: Wei sheng yan jiu = Journal of hygiene research 20080101

Title: Suppression of mutagens-induced SOS response by phytoncide solution using Salmonella typhimurium TA1535/pSK1002 umu test.

Journal: Journal of oleo science 20080101

Title: The Hypocrea jecorina (Trichoderma reesei) hypercellulolytic mutant RUT C30 lacks a 85 kb (29 gene-encoding) region of the wild-type genome.

Journal: BMC genomics 20080101

Title: Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.

Journal: PloS one 20080101

Title: Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB.

Journal: Journal of ovarian research 20080101

Title: Evaluation of comparative and combined antimutagenic potential of vitamin C and vitamin E using histidine mutant Salmonella typhimurium strains.

Journal: Indian journal of clinical biochemistry : IJCB 20080101

Title: Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.

Journal: European journal of pharmacology 20071114

Title: Mercuric dichloride induces DNA damage in human salivary gland tissue cells and lymphocytes.

Journal: Archives of toxicology 20071101

Title: Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas.

Journal: Therapeutics and clinical risk management 20071001

Title: N-methyl-N'-nitro-N-nitrosoguanidine activates multiple cell death mechanisms in human fibroblasts.

Journal: DNA and cell biology 20070901

Title: Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair.

Journal: Cell death and differentiation 20070801

Title: DNA damage induces alternative lengthening of telomeres (ALT) associated promyelocytic leukemia bodies that preferentially associate with linear telomeric DNA.

Journal: Cancer research 20070801

Title: Animal models of stomach carcinogenesis.

Journal: Toxicologic pathology 20070801

Title: Exposure to the tobacco smoke constituent 4-aminobiphenyl induces chromosomal instability in human cancer cells.

Journal: Cancer research 20070801

Title: The cda GenoTox assay: a new and sensitive method for detection of environmental genotoxins, including nitroarenes and aromatic amines.

Journal: Mutation research 20070728

Title: Combined treatment with green tea catechins and sodium nitrite selectively promotes rat forestomach carcinogenesis after initiation with N-methyl-N'- nitro-N-nitrosoguanidine.

Journal: Cancer science 20070701

Title: Proliferation, angiogenesis and apoptosis-associated proteins are molecular targets for chemoprevention of MNNG-induced gastric carcinogenesis by ethanolic Ocimum sanctum leaf extract.

Journal: Singapore medical journal 20070701

Title: Effects of aqueous extracts of medicinal plants on MNNG-treated rat hepatocytes in primary cultures.

Journal: Journal of ethnopharmacology 20070530

Title: Chemical carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine, is a specific activator of oncogenic Ras.

Journal: Cell cycle (Georgetown, Tex.) 20070515

Title: Modulatory effects of black tea polyphenols on oxidant-antioxidant profile and expression of proliferation, apoptosis, and angiogenesis-associated proteins in the rat forestomach carcinogenesis model.

Journal: Journal of gastroenterology 20070501

Title: Heat shock does not induce gammaH2AX foci formation but protects cells from N-methyl-N'-nitro-N-nitrosoguanidine-induced genotoxicity.

Journal: Mutation research 20070420

Title: Methylation profiles of CpG island loci in major types of human cancers.

Journal: Journal of Korean medical science 20070401

Title: [Chemopreventive effect of oxymatrine on N-methyl-N'-nitro-N-nitrosoguanidine induced gastrointestinal cancer: experiment with rats].

Journal: Zhonghua yi xue za zhi 20070327

Title: Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.

Journal: Experimental cell research 20070310

Title: The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair.

Journal: Biological & pharmaceutical bulletin 20070301

Title: Esophageal thermal injury by hot adlay tea.

Journal: The Korean journal of internal medicine 20070301

Title: Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults.

Journal: Biochemical pharmacology 20070215

Title: Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.

Journal: Oncogene 20070111

Title: Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents.

Journal: Cancer research 20070101

Title: Effects of eradication of Helicobacter pylori on gastric carcinogenesis in experimental models.

Journal: Journal of gastroenterology 20070101

Title: Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.

Journal: International journal of toxicology 20070101

Title: Genome position and gene amplification.

Journal: Genome biology 20070101

Title: Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer.

Journal: BMC evolutionary biology 20070101

Title: [Microbioluminescent study of the general toxicity and mutagenicity of pollutants].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20070101

Title: [Induction of the SOS response in Escherichia coli cells under osmotic stress and in the presence of N-methyl-N'-nitro-N-nitrosoguanidine].

Journal: Mikrobiologiia 20070101

Title: Four-week short chain fructo-oligosaccharides ingestion leads to increasing fecal bifidobacteria and cholesterol excretion in healthy elderly volunteers.

Journal: Nutrition journal 20070101

Title: Discussion on the use of taxanes for treatment of breast cancers in BRCA1 mutations carriers.

Journal: Hereditary cancer in clinical practice 20070101

Title: Modulatory effects of black tea polyphenols on rat forestomach carcinogenesis.

Journal: Toxicology mechanisms and methods 20070101

Title: Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay.

Journal: Mutation research 20061201

Title: Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks.

Journal: Chemical research in toxicology 20061201

Title: Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair.

Journal: The Journal of biological chemistry 20061103

Title: DBA/2 mouse skin is unresponsive to dermal tumor promotion by cigarette smoke condensate.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20061101

Title: In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens.

Journal: Mutation research 20061010

Title: Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on hepatic damage caused by benzo[a]pyrene.

Journal: Journal of ethnopharmacology 20060919

Title: A comparative study of using comet assay and gammaH2AX foci formation in the detection of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060901

Title: Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.

Journal: European journal of medical research 20060830

Title: Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide.

Journal: Cancer letters 20060808

Title: [Screening of a low alcohol dehydrogenase activity mutant of rhizopus oryzae and the regulation of Zn2+ and Mg2+].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20060801

Title: Comparative evaluation of the alkaline comet assay with the micronucleus test for genotoxicity monitoring using aquatic organisms.

Journal: Ecotoxicology and environmental safety 20060701

Title: Involvement of the drug efflux protein TolC in mutagenicity induced by MNNG or Trp-P-2.

Journal: Mutation research 20060616

Title: Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death.

Journal: The Biochemical journal 20060615

Title: Effects of co-exposure to extremely low frequency (50 Hz) magnetic fields and xenobiotics determined in vitro by the alkaline comet assay.

Journal: The Science of the total environment 20060515

Title: dUTP Pyrophosphatase, its appearance in extracellular compartment may serve as a potential biomarker for N-methyl-N'-nitro-N-nitrosoguanidine exposure in mammalian cells.

Journal: Proteomics 20060501

Title: Sister chromatid exchange and micronuclei in human peripheral blood lymphocytes treated with thyroxine in vitro.

Journal: Mutation research 20060430

Title: Induced endoplasmic reticulum (ER) stress and binding of over-expressed ER specific chaperone GRP78/BiP with dimerized epidermal growth factor receptor in mammalian cells exposed to low concentration of N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Mutation research 20060411

Title: [The role of JWA in N-methyl-N'-nitro-N-nitrosoguanidine induced human bronchial epithelial cell apoptosis].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060401

Title: Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation.

Journal: The Journal of biological chemistry 20060331

Title: Cytotoxic and genotoxic effects of resin monomers in human salivary gland tissue and lymphocytes as assessed by the single cell microgel electrophoresis (Comet) assay.

Journal: Biomaterials 20060301

Title: Proteomic analysis of beryllium-induced genotoxicity in an Escherichia coli mutant model system.

Journal: Proteomics 20060301

Title: Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine: possible contribution of nitric oxide-associated oxidative DNA damage.

Journal: Cancer science 20060301

Title: Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.

Journal: International journal of cancer 20060201

Title: Proteomic profiling for cellular responses to different concentrations of N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Journal of proteome research 20060201

Title: Inhibitory effects of caraway (Carum carvi L. ) and its component on N-methyl-N'-nitro-N-nitrosoguanidine-induced mutagenicity.

Journal: The journal of medical investigation : JMI 20060201

Title: Strain improvement of Candida tropicalis for the production of xylitol: biochemical and physiological characterization of wild-type and mutant strain CT-OMV5.

Journal: Journal of microbiology (Seoul, Korea) 20060201

Title: Induction of gastric GIST in rat and establishment of GIST cell line.

Journal: Cancer letters 20060118

Title: Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest.

Journal: BMC cancer 20060101

Title: Is translational research compatible with preclinical publication strategies?

Journal: Radiation oncology (London, England) 20060101

Title: Chemopreventive effects of rofecoxib and folic acid on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

Journal: Chinese journal of digestive diseases 20060101

Title: Inhibition of N-Methyl N'-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis by Phyllanthus amarus extract.

Journal: Asian Pacific journal of cancer prevention : APJCP 20060101

Title: TILLING is an effective reverse genetics technique for Caenorhabditis elegans.

Journal: BMC genomics 20060101

Title: Imatinib (STI571) inhibits DNA repair in human leukemia oncogenic tyrosine kinase-expressing cells.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

Title: Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Ha-ras-transfected BALB/c 3T3 cells (Bhas 42 cells).

Journal: Mutation research 20051207

Title: Biochemical characterization of N-methyl N'-nitro-N-nitrosoguanidine-induced cadmium resistant mutants of Aspergillus niger.

Journal: Journal of biosciences 20051201

Title: Function of domains of human O6-alkylguanine-DNA alkyltransferase.

Journal: Biochemistry 20051122

Title: Role of O6-methylguanine-DNA methyltransferase and effect of O6-benzylguanine on the anti-tumor activity of cis-diaminedichloroplatinum(II) in oral cancer cell lines.

Journal: Oral oncology 20051101

Title: Genotoxicity of nicotine in mini-organ cultures of human upper aerodigestive tract epithelia.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051101

Title: Differential effects of cisplatin and MNNG on dna mutants of Escherichia coli.

Journal: Mutation research 20051015

Title: N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner.

Journal: Molecular pharmacology 20051001

Title: Antimutagenic and anti-oxidant activities of the non-steroidal anti-inflammatory drug celecoxib.

Journal: Clinical and experimental pharmacology & physiology 20051001

Title: The apoptosis inhibitory domain of FE65-like protein 1 regulates both apoptotic and caspase-independent programmed cell death mediated by tumor necrosis factor.

Journal: Biochemical and biophysical research communications 20050923

Title: Apaf-1 deficient mouse fibroblasts are resistant to MNNG and MMS-induced apoptotic death without attenuation of Bcl-2 decline.

Journal: Toxicology and applied pharmacology 20050901

Title: Homologous recombination rescues mismatch-repair-dependent cytotoxicity of S(N)1-type methylating agents in S. cerevisiae.

Journal: Current biology : CB 20050809

Title: Assay to measure CD59 mutations in CHO A(L) cells using flow cytometry.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20050801

Title: Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20050801

Title: A lipidomic study of the effects of N-methyl-N'-nitro-N-nitrosoguanidine on sphingomyelin metabolism.

Journal: Acta biochimica et biophysica Sinica 20050801

Title: [Cell proliferation inhibitive and apoptosis promoting effects of sanchi extract on GES-1 cell after being transformed by MNNG].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050801

Title: Comet assay with the fish cell line rainbow trout gonad-2 for in vitro genotoxicity testing of xenobiotics and surface waters.

Journal: Environmental toxicology and chemistry 20050801

Title: Screening of potential lactobacilli antigenotoxicity by microbial and mammalian cell-based tests.

Journal: International journal of food microbiology 20050625

Title: Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050601

Title: Induction of apoptosis and inhibition of cyclooxygenase-2 expression by N-methyl-N'-nitro-N-nitrosoguanidine in human leukemia cells.

Journal: Anti-cancer drugs 20050601

Title: Sphingolipids are involved in N-methyl-N'-nitro-N-nitrosoguanidine-induced epidermal growth factor receptor clustering.

Journal: Biochemical and biophysical research communications 20050506

Title: Application of a two-stage Syrian hamster embryo cell transformation assay to cigarette smoke particulate matter.

Journal: Mutation research 20050502

Title: Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.

Journal: Mutagenesis 20050501

Title: Degradation of human exonuclease 1b upon DNA synthesis inhibition.

Journal: Cancer research 20050501

Title: Identification of mutation sites on delta6 desaturase genes from Mortierella alpina 1S-4 mutants.

Journal: Bioscience, biotechnology, and biochemistry 20050501

Title: Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum.

Journal: The Journal of biological chemistry 20050429

Title: Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction.

Journal: The Journal of biological chemistry 20050429

Title: Attenuation of N-methyl-N'-nitro-N-nitrosoguanidine induced genotoxicity and oxidative stress by tomato and garlic combination.

Journal: Life sciences 20050325

Title: High doses of SN1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair.

Journal: Cell cycle (Georgetown, Tex.) 20050301

Title: N-methyl-N'-nitro-N-nitrosoguanidine interferes with the epidermal growth factor receptor-mediated signaling pathway.

Journal: Mutation research 20050301

Title: The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.

Journal: Thrombosis and haemostasis 20050301

Title: Modulation effect of tea polyphenol toward N-methyl-N'-nitro-N-nitrosoguanidine-induced precancerous gastric lesion in rats.

Journal: The Journal of nutritional biochemistry 20050301

Title: [Apoptosis-promoting effect of Panax notoginseng extracts on MNNG-transformed GES-1 cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20050301

Title: [Gene expression profiles in early stage of BALB/c 3T3 cells' transformation promoted with 12-O-tetradecanoylphorbol-13-acetate].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20050301

Title: Acrylamide and glycidamide: genotoxic effects in V79-cells and human blood.

Journal: Mutation research 20050207

Title: NAD+ as a metabolic link between DNA damage and cell death.

Journal: Journal of neuroscience research 20050101

Title: The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways.

Journal: Toxicology and applied pharmacology 20050101

Title: Polyamines modulate carcinogen-induced mutagenesis in vivo.

Journal: Environmental and molecular mutagenesis 20050101

Title: Novel mutation method for increased cellulase production.

Journal: Journal of applied microbiology 20050101

Title: Recognition and binding of mismatch repair proteins at an oncogenic hot spot.

Journal: BMC molecular biology 20050101

Title: Genotoxic effects of pentachlorophenol, lindane, transfluthrin, cyfluthrin, and natural pyrethrum on human mucosal cells of the inferior and middle nasal conchae.

Journal: American journal of rhinology 20050101

Title: Symbiotic effectiveness of a siderophore overproducing mutant of Mesorhizobium ciceri.

Journal: Polish journal of microbiology 20050101

Title: The distribution of SNPs in human gene regulatory regions.

Journal: BMC genomics 20050101

Title: Combination chemoprevention of experimental gastric carcinogenesis by s-allylcysteine and lycopene: modulatory effects on glutathione redox cycle antioxidants.

Journal: Journal of medicinal food 20050101

Title: Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20041221

Title: Role of mismatch-specific uracil-DNA glycosylase in repair of 3,N4-ethenocytosine in vivo.

Journal: DNA repair 20041202

Title: Dark lumen magnetic resonance colonography in a rodent polyp model: initial experience and demonstration of feasibility.

Journal: Investigative radiology 20041201

Title: N-methyl-N'-nitro-N-nitrosoguanidine sensitivity, mutator phenotype and sequence specificity of spontaneous mutagenesis in FEN-1-deficient cells.

Journal: Mutation research 20041122

Title: MNNG-induced mutations in the adult gill and hepatopancreas and in embryos of rpsL transgenic zebrafish.

Journal: Mutation research 20041122

Title: [Inhibiting effects of Panax notoginseng extracts on proliferation of GES-1 cells and MNNG-transformed GES-1 cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20041101

Title: Induction of apoptosis and G2/M arrest by N-methyl-N'-nitro-N-nitrosoguanidine in human prostate carcinoma cells.

Journal: Mutation research 20041010

Title: A protective role for matrix metalloproteinase-3 in squamous cell carcinoma.

Journal: Cancer research 20041001

Title: In vivo detection of gastric cancer in rats by electron paramagnetic resonance imaging.

Journal: Cancer research 20040915

Title: Protective effect of tomato against N-methyl-N'-nitro-N-nitrosoguanidine-induced in vivo clastogenicity and oxidative stress.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20040901

Title: Characterization of Streptomyces scabies mutants deficient in melanin biosynthesis.

Journal: Canadian journal of microbiology 20040901

Title: Poly(ADP-ribose) glycohydrolase as a target for neuroprotective intervention: assessment of currently available pharmacological tools.

Journal: European journal of pharmacology 20040816

Title: Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.

Journal: Molecular cancer therapeutics 20040801

Title: Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction.

Journal: Biochimica et biophysica acta 20040723

Title: The use of mini-organ cultures of human upper aerodigestive tract epithelia in ecogenotoxicology.

Journal: Mutation research 20040711

Title: Depleted dopamine in gastric cancer tissues: dopamine treatment retards growth of gastric cancer by inhibiting angiogenesis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040701

Title: Response of REV3 promoter to N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Mutation research 20040604

Title: Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.

Journal: Genes & development 20040601

Title: Persistence of gene expression changes in stomach mucosae induced by short-term N-methyl-N'-nitro-N-nitrosoguanidine treatment and their presence in stomach cancers.

Journal: Mutation research 20040518

Title: Effect of duodenogastric reflux on N-methyl-N'-nitro-N-nitrosoguanidine-induced glandular stomach tumorigenesis in Helicobacter pylori-infected Mongolian gerbils.

Journal: Oncology reports 20040501

Title: Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition.

Journal: The Journal of biological chemistry 20040430

Title: Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.

Journal: The Journal of biological chemistry 20040402

Title: Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations.

Journal: DNA repair 20040401

Title: Protein phosphatase inhibitor-1 mRNA expression correlates with neoplastic transformation of epithelial liver cells and progression of hepatocellular carcinomas.

Journal: International journal of oncology 20040401

Title: An investigation of DNA excision repair capacity in human CD4+ T cell clones as a function of age in vitro.

Journal: Experimental gerontology 20040401

Title: Enhanced stimulation of chromosomal translocations by radiomimetic DNA damaging agents and camptothecin in Saccharomyces cerevisiae rad9 checkpoint mutants.

Journal: Mutation research 20040322

Title: Exposure of mouse skin to organic peroxides: subchronic effects related to carcinogenic potential.

Journal: Carcinogenesis 20040301

Title: Genotoxicity and cytotoxicity of dental materials in human lymphocytes as assessed by the single cell microgel electrophoresis (comet) assay.

Journal: Journal of dentistry 20040301

Title: The Neurospora crassa mus-19 gene is identical to the qde-3 gene, which encodes a RecQ homologue and is involved in recombination repair and postreplication repair.

Journal: Current genetics 20040201

Title: Chemoprevention of gastric cancer by celecoxib in rats.

Journal: Gut 20040201

Title: Cloning and sequencing of the ura3 and ura5 genes, and isolation and characterization of uracil auxotrophs of the fungus Mortierella alpina 1S-4.

Journal: Bioscience, biotechnology, and biochemistry 20040201

Title: Developing a genetic system in Deinococcus radiodurans for analyzing mutations.

Journal: Genetics 20040201

Title: Protective effects of ethanolic neem leaf extract on N-methyl-N'-nitro-N-nitrosoguanidine-induced genotoxicity and oxidative stress in mice.

Journal: Drug and chemical toxicology 20040201

Title: Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.

Journal: Oncogene 20040115

Title: Msh2 deficiency does not contribute to cisplatin resistance in mouse embryonic stem cells.

Journal: Oncogene 20040108

Title: Characterization of components of the mismatch repair machinery in Trypanosoma brucei.

Journal: Molecular microbiology 20040101

Title: N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA.

Journal: Molecular cancer 20040101

Title: Proteomic analysis of cellular responses to low concentration N-methyl-N'-nitro-N-nitrosoguanidine in human amnion FL cells.

Journal: Environmental and molecular mutagenesis 20040101

Title: Improvement of carotenoid-synthesizing yeast Rhodotorula rubra by chemical mutagenesis.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Title: Anti-stress activity of Propionibacterium freudenreichii : identification of a reactivative protein.

Journal: Antonie van Leeuwenhoek 20040101

Title: Protective effect of S-allylcysteine and lycopene in combination against N-methyl-N'-nitro-N-nitrosoguanidine-induced genotoxicity.

Journal: Polish journal of pharmacology 20040101

Title: Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.

Journal: Cytogenetic and genome research 20040101

Title: Prevention and repair of DNA damage by selected phytochemicals as measured by single cell gel electrophoresis.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101

Title: Effects of aqueous extracts of garlic (Allium sativum) and neem (Azadirachta indica) leaf on hepatic and blood oxidant-antioxidant status during experimental gastric carcinogenesis.

Journal: Journal of medicinal food 20040101

Title: Proteome analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasis-related proteins.

Journal: Journal of proteome research 20040101

Title: [Evaluation of genotoxic and/or co-genotoxic effects in cells exposed in vitro to extremely-low frequency electromagnetic fields].

Journal: Annali di igiene : medicina preventiva e di comunita 20040101

Title: The exceptionally high rate of spontaneous mutations in the polymerase delta proofreading exonuclease-deficient Saccharomyces cerevisiae strain starved for adenine.

Journal: BMC genetics 20040101

Title: Lignin-stimulated reduction of oxidative DNA lesions in testicular cells and lymphocytes of sprague-dawley rats in vitro and ex vivo.

Journal: Nutrition and cancer 20040101

Title: Differences in responses of plant hairy roots to chemical toxicity compared between primary and ramified roots.

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20040101

Title: Enhanced production of L-lactic acid by ammonia-tolerant mutant strain Rhizopus sp. MK-96-1196.

Journal: Journal of bioscience and bioengineering 20040101

Title: N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Report on carcinogens : carcinogen profiles 20040101

Title: Genotoxic effects of vanadium pentoxide on human peripheral lymphocytes and mucosal cells of the upper aerodigestive tract.

Journal: International journal of environmental health research 20031201

Title: beta-Catenin mutations and nuclear accumulation during progression of rat stomach adenocarcinomas.

Journal: Cancer science 20031201

Title: Mismatch repair-dependent transcriptome changes in human cells treated with the methylating agent N-methyl-n'-nitro-N-nitrosoguanidine.

Journal: Cancer research 20031201

Title: Differential expression of genes related to levels of mucosal cell proliferation among multiple rat strains by using oligonucleotide microarrays.

Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20031201

Title: MNNG induces dramatic DNA damage and non-apoptotic changes in cervical carcinoma HeLa cells.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Polyozellus multiplex, a Korean wild mushroom, as a potent chemopreventive agent against stomach cancer.

Journal: Life sciences 20031107

Title: Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related.

Journal: Mutation research 20031101

Title: Antimutagenic activity of phenylpropanoids from clove (Syzygium aromaticum).

Journal: Journal of agricultural and food chemistry 20031022

Title: Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.

Journal: European journal of medical research 20031022

Title: Antimutagenic activity of flavonoids from Chrysanthemum morifolium.

Journal: Bioscience, biotechnology, and biochemistry 20031001

Title: N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced in vivo clastogenicity: protective effects of aqueous neem leaf extract.

Journal: Die Pharmazie 20031001

Title: [Proteomic analysis of cellular responses to low concentration of N-methyl-N'-nitro-N-nitrosoguanidine in human amnion FL cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20031001

Title: [Cloning and bioinformatics of human REV3 gene promoter region and its response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20031001

Title: The mutational spectrum of the HPRT gene from human T cells in vivo shares a significant concordant set of hot spots with MNNG-treated human cells.

Journal: Cancer research 20030915

Title: NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes.

Journal: Biochemical and biophysical research communications 20030905

Title: Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030903

Title: Enhancement by interleukin-1 beta of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats: a possible mechanism for Helicobacter pylori-associated gastric carcinogenesis.

Journal: Cancer letters 20030820

Title: Non-apoptogenic killing of hela cervical carcinoma cells after short exposure to the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Journal: Journal of cellular biochemistry 20030815

Title: Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030801

Title: Activation of protein kinase A and clustering of cell surface receptors by N-methyl-N'-nitro-N-nitrosoguanidine are independent of genomic DNA damage.

Journal: Mutation research 20030725

Title: Expression of survivin in human gastric carcinoma and gastric carcinoma model of rats.

Journal: World journal of gastroenterology 20030715

Title: Application of Euglena gracilis cells to comet assay: evaluation of DNA damage and repair.

Journal: Mutation research 20030708

Title: Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701

Title: Chemoprotective effects of ethanolic extract of neem leaf against MNNG-induced oxidative stress.

Journal: Die Pharmazie 20030701

Title: Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).

Journal: Toxicology 20030630

Title: [Morphological transformation of mouse NIH3T3 cells induced by nickel refining dusts in vitro].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20030601

Title: Response of human REV3 gene to gastric cancer inducing carcinogen N-methyl-N'-nitro-N-nitrosoguanidine and its role in mutagenesis.

Journal: World journal of gastroenterology 20030515

Title: Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1.

Journal: The EMBO journal 20030501

Title: Global expression analysis of N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas using oligonucleotide microarrays.

Journal: Carcinogenesis 20030501

Title: Suppression by iron chelator phenanthroline of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.

Journal: Cancer letters 20030227

Title: Myenteric denervation reduces the incidence of gastric tumors in rats.

Journal: Cancer letters 20030210

Title: p16 hypermethylation during gastric carcinogenesis of Wistar rats by N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Mutation research 20030205

Title: [Preservation of mucosal specimens before processing in the alkaline single cell microgel electrophoresis assay].

Journal: HNO 20030201

Title: Molecular and cellular influences of butylated hydroxyanisole on Chinese hamster V79 cells treated with N-methyl-N'-nitro-N-nitrosoguanidine: antimutagenicity of butylated hydroxyanisole.

Journal: Environmental and molecular mutagenesis 20030101

Title: The QDE-3 homologue RecQ-2 co-operates with QDE-3 in DNA repair in Neurospora crassa.

Journal: Current genetics 20030101

Title: Anticlastogenic, antigenotoxic and apoptotic activity of epigallocatechin gallate: a green tea polyphenol.

Journal: Mutation research 20030101

Title: Isolation and characterisation of phycobiliprotein rich mutant of cyanobacterium Synechocystis sp.

Journal: Acta biologica Hungarica 20030101

Title: Competition among Bradyrhizobium strains for nodulation of green gram (Vigna radiata): use of dark-nodule strain.

Journal: Folia microbiologica 20030101

Title: Altered expression of zinc finger proteins, ADAMs, and integrin-related proteins following treatment of cultured human cells with a low concentration of N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Environmental and molecular mutagenesis 20030101

Title: Selection of biochemical mutants of Aspergillus niger resistant to some abiotic stresses with increased inulinase production.

Journal: Journal of applied microbiology 20030101

Title: Ethanolic neem leaf extract protects against N-methyl -N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in Wistar rats.

Journal: Asian Pacific journal of cancer prevention : APJCP 20030101

Title: Genetic determination of ploidy level in Xanthophyllomyces dendrorhous.

Journal: Antonie van Leeuwenhoek 20030101

Title: Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis.

Journal: BMC cancer 20030101

Title: Abnormal expression of gastric mucin in human and rat aberrant crypt foci during colon carcinogenesis.

Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20030101

Title: Role of APC and DNA mismatch repair genes in the development of colorectal cancers.

Journal: Molecular cancer 20030101

Title: Effect of S-allylcysteine on oxidant-antioxidant status during N-methyl-N'-nitro-N-nitrosoguanidine and saturated sodium chloride-induced gastric carcinogenesis in Wistar rats.

Journal: Asia Pacific journal of clinical nutrition 20030101

Title: Reduction of genotoxic effects of the carcinogen N-methyl-N'-nitro-N-nitrosoguanidine by dietary lignin in mammalian cells cultured in vitro.

Journal: Nutrition and cancer 20030101

Title: Quinoprotein alcohol dehydrogenase is involved in catabolic acetate production, while NAD-dependent alcohol dehydrogenase in ethanol assimilation in Acetobacter pasteurianus SKU1108.

Journal: Journal of bioscience and bioengineering 20030101

Title: Chemoprotection against N-methyl-n'-nitro-N-nitrosoguanidine-induced oxidative stress by s-allylcysteine, a garlic constituent, in wistar rats.

Journal: Toxicology mechanisms and methods 20030101

Title: Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity.

Journal: Cancer letters 20021215

Title: Antiperoxidative effects of lycopene during N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis.

Journal: Fitoterapia 20021201

Title: Characterization of gene expression changes associated with MNNG, arsenic, or metal mixture treatment in human keratinocytes: application of cDNA microarray technology.

Journal: Environmental health perspectives 20021201

Title: ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation.

Journal: The Journal of biological chemistry 20021011

Title: Different genetic alterations in rat forestomach tumors induced by genotoxic and non-genotoxic carcinogens.

Journal: Carcinogenesis 20021001

Title: Serum trace elements status of rabbits supplemented with Nigella sativa, vitamins C and E, and selenium against damage by N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Biological trace element research 20021001

Title: Appearance of osteonectin-expressing fibroblastic cells in early rat stomach carcinogenesis and stomach tumors induced with N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Japanese journal of cancer research : Gann 20020901

Title: Effects of weaning by surrogate mothers (ACI) on tumor development in SD rats treated with methylnitrosourea (MNU) and/or N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Journal: Hiroshima journal of medical sciences 20020901

Title: Effects of N-methyl-N'-nitro-N-nitrosoguanidine on the human colorectal polyps consecutively maintained in SCID mice.

Journal: Cancer letters 20020828

Title: Cadmium affects genes involved in growth regulation during two-stage transformation of Balb/3T3 cells.

Journal: Toxicology 20020815

Title: Effects of vitamins C and E on cytotoxicity induced by N-nitroso compounds, N-nitrosomorpholine and N-methyl-N'-nitro-N-nitrosoguanidine in Caco-2 and V79 cell lines.

Journal: Cancer letters 20020808

Title: Pseudouridine, an antimutagenic substance in beer towards N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801

Title: Cytoprotective features of selenazofurin in hematopoietic cells.

Journal: International journal of clinical pharmacology and therapeutics 20020801

Title: Dendritic cell appearance and differentiation during early and late stages of rat stomach carcinogenesis.

Journal: Japanese journal of cancer research : Gann 20020801

Title: Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701

Title: Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53.

Journal: Chemical research in toxicology 20020601

Title: Profiling and selection of genes differentially expressed in the pylorus of rat strains with different proliferative responses and stomach cancer susceptibility.

Journal: Carcinogenesis 20020601

Title: Thiourea toxicity in mouse C3H/10T1/2 cells expressing human flavin-dependent monooxygenase 3.

Journal: Biochemical pharmacology 20020601

Title: Establishment of cisplatin-resistant variants of human neuroblastoma cell lines, TGW and GOTO, and their drug cross-resistance profiles.

Journal: Cancer chemotherapy and pharmacology 20020601

Title: Cytotoxic and antimutagenic stilbenes from seeds of Paeonia lactiflora.

Journal: Archives of pharmacal research 20020601

Title: Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana.

Journal: Archives of pharmacal research 20020601

Title: Antimutagenic effect of amino acids on the mutagenicity of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Journal: Bioscience, biotechnology, and biochemistry 20020601

Title: Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine.

Journal: Free radical research 20020601

Title: Promoting effects of combined antioxidant and sodium nitrite treatment on forestomach carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Cancer letters 20020408

Title: Polyetheretherketone--cytotoxicity and mutagenicity in vitro.

Journal: Biomaterials 20020401

Title: [Analysis of function of the 452 bp sequence proceeding the pgiB gene in Bacillus stearothermophilus].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20020401

Title: Low expression of cyclin D2 in G2/M-arrested and transformed proliferating Balb/3T3 cells.

Journal: The Journal of veterinary medical science 20020301

Title: Antimutagenicity of Murdannia loriformis in the Salmonella mutation assay and its inhibitory effects on azoxymethane-induced DNA methylation and aberrant crypt focus formation in male F344 rats.

Journal: The journal of medical investigation : JMI 20020201

Title: Prevention of N-methyl-N'-nitro-N-nitrosoguanidine and saturated sodium chloride-induced gastric carcinogenesis in Wistar rats by lycopene.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20020201

Title: Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens.

Journal: Mutation research 20020115

Title: Green fluorescent protein-based biosensor for detecting SOS-inducing activity of genotoxic compounds.

Journal: Journal of microbiological methods 20020101

Title: Vitamin C and quercetin modulate DNA-damaging effect of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20020101

Title: Development, characterization, and preliminary evaluation of a temperature-sensitive mutant of Ornithobacterium rhinotracheale for potential use as a live vaccine in turkeys.

Journal: Avian diseases 20020101

Title: Inhibition by long-term fermented miso of induction of gastric tumors by N-methyl-N'-nitro-N-nitrosoguanidine in CD (SD) rats.

Journal: Oncology reports 20020101

Title: The influence of pylorus-preserving partial gastrectomy on carcinogenesis of residual gastric mucosa in the rat.

Journal: Surgery today 20020101

Title: Duodenogastric reflux and gastric stump carcinoma.

Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20020101

Title: Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers.

Journal: BMC microbiology 20020101

Title: N-Methyl-N'-nitro-N-nitrosoguanidine.

Journal: Report on carcinogens : carcinogen profiles 20020101

Title: Lack of mutagenic and co-mutagenic effects of magnetic fields during magnetic resonance imaging.

Journal: Journal of magnetic resonance imaging : JMRI 20011201

Title: Spontaneous and MNNG-induced reversion of an EGFP construct in HeLa cells: an assay for observing mutations in living cells by fluorescent microscopy.

Journal: Human mutation 20011201

Title: Attenuation of catalase activity in the malignant phenotype plays a functional role in an in vitro model for tumor progression.

Journal: Cancer letters 20011128

Title: Repair of O(6)-methylguanine is not affected by thymine base pairing and the presence of MMR proteins.

Journal: Mutation research 20011101

Title: Contribution of apoptosis to responses in the comet assay.

Journal: Mutation research 20011018

Title: Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase in an amplification phase of tumor necrosis factor-induced apoptosis.

Journal: The Journal of biological chemistry 20011012

Title: Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20011009

Title: p53 Phosphorylation at serine 15 is required for transcriptional induction of the plasminogen activator inhibitor-1 (PAI-1) gene by the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: The Journal of biological chemistry 20010928

Title: Partial chemical/structural elucidation of anti-mutagenic compounds from corn.

Journal: Toxicology 20010925

Title: Quantification of changes in c-myc mRNA levels in normal human bronchial epithelial (NHBE) and lung adenocarcinoma (A549) cells following chemical treatment.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010901

Title: hMSH3 overexpression and cellular response to cytotoxic anticancer agents.

Journal: Carcinogenesis 20010801

Title: Suppression of chemical mutagen-induced SOS response by alkylphenols from clove (Syzygium aromaticum) in the Salmonella typhimurium TA1535/pSK1002 umu test.

Journal: Journal of agricultural and food chemistry 20010801

Title: Biological production of optically active muconolactones by Rhodococcus rhodochrous.

Journal: Applied microbiology and biotechnology 20010801

Title: [Role of hydrogen peroxide in promoting proliferation and transformation of rat liver oval cell line WB-F344].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20010801

Title: Attenuation by ambroxol of monochloramine-enhanced gastric carcinogenesis: a possible prevention against Helicobacter pylori-associated gastric carcinogenesis.

Journal: Cancer letters 20010726

Title: Low concentration N-methyl-N'-nitro-N-nitrosoguanidine activates DNA polymerase-beta expression via cyclic-AMP-protein kinase A-cAMP response element binding protein pathway.

Journal: Mutation research 20010701

Title: Cell cycle was disturbed in the MNNG-induced initiation stage during in vitro two-stage transformation of Balb/3T3 cells.

Journal: Toxicology 20010621

Title: Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner.

Journal: Oncogene 20010614

Title: Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20010601

Title: Sequential histopathological changes in vivo after suicide gene therapy of gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

Journal: Japanese journal of cancer research : Gann 20010601

Title: p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents.

Journal: The Journal of biological chemistry 20010525

Title: Anti-genotoxicity of trans-anethole and eugenol in mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010501

Title: Effect of mild whole body hyperthermia on cytotoxic action of N-methyl-N'-nitro-N-nitrosoguanidine in Swiss mice.

Journal: Toxicology letters 20010408

Title: Mutagen sensitivity of nasopharyngeal cancer patients.

Journal: Mutation research 20010405

Title: Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT.

Journal: International journal of cancer 20010401

Title: Cadmium-induced alterations of connexin expression in the promotion stage of in vitro two-stage transformation.

Journal: Toxicology 20010321

Title: Development and application of a sensitive and rapid immunoassay for the quantitation of N7-methyldeoxyguanosine in DNA samples.

Journal: Chemical research in toxicology 20010301

Title: Alkylating agent and chromatin structure determine sequence context-dependent formation of alkylpurines.

Journal: Journal of molecular biology 20010216

Title: [The role of Helicobacter pylori infection and effect of eradication in experimental animal models of gastric carcinogenesis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010201

Title: Isolation and characterization of the Enterobacter cloacae cheR mutant defective in phosphate taxis.

Journal: Bioscience, biotechnology, and biochemistry 20010201

Title: Topoisomerase I-mediated cytotoxicity of N-methyl-N'-nitro-N-nitrosoguanidine: trapping of topoisomerase I by the O6-methylguanine.

Journal: Cancer research 20010101

Title: Differences in carcinogenesis by the length of carcinogen exposure period in rat colon.

Journal: Digestive diseases and sciences 20010101

Title: [Extracellular protein of propionic acid bacteria inhibits induced mutation in strains of Salmonella typhimurium].

Journal: Mikrobiologiia 20010101

Title: Joint effects of citrus peel use and black tea intake on the risk of squamous cell carcinoma of the skin.

Journal: BMC dermatology 20010101

Title: [Characteristics of mutants of Streptomyces peucetius subsp. caesius ATCC 27952 resistant to anthracycline antibiotics].

Journal: Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20010101

Title: L-glutamate production by lysozyme-sensitive Corynebacterium glutamicum ltsA mutant strains.

Journal: BMC biotechnology 20010101

Title: Induction by bombesin of peritoneal metastasis of gastric cancers induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.

Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20010101

Title: Protection of N-methyl-N'-nitro-N-nitrosoguanidine-induced in vivo clastogenicity by aqueous garlic extract.

Journal: Asia Pacific journal of clinical nutrition 20010101

Title: Novel DNA repair alkyltransferase from Caenorhabditis elegans.

Journal: Environmental and molecular mutagenesis 20010101

Title: Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride in rats.

Journal: Anticancer research 20010101

Title: Isolation and analysis of lipase-overproducing mutants of Serratia marcescens.

Journal: Journal of bioscience and bioengineering 20010101

Title: Promoting effects of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone on rat glandular stomach carcinogenesis initiated with N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Cancer research 19990501

Title: A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage.

Journal: Carcinogenesis 19980601

Title: Strain differences in mouse skin tumorigenesis by the promotion of 12-o-tetradecanoylphorbol-13-acetate or benzoyl peroxide.

Journal: Oncology reports 19950501

Title: Effects of caffeine on glandular stomach carcinogenesis induced in rats by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19950101

Title: Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.

Journal: Cancer research 19920615

Title: Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.

Journal: Cancer research 19920101

Title: Induction of altered hepatocellular foci of hamster for a possible short-term assay for carcinogens.

Journal: Research communications in chemical pathology and pharmacology 19890301

Title: [Promoting effect of bile acids on gastric carcinogenesis induced by MNNG in rats].

Journal: Nihon Geka Gakkai zasshi 19890101

Title: Effects of sodium chloride, saccharin, phenobarbital and aspirin on gastric carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.

Journal: Gan 19840601

Title: Experimental models for gastric leiomyosarcoma. The effects of N-methyl-N'-nitro-N-nitrosoguanidine in combination with stress, aspirin, or sodium taurocholate.

Journal: Cancer 19840301

Title: Cocarcinogenic action of aspirin on gastric tumors induced by N-nitroso-N-methylnitroguanidine in rats.

Journal: Journal of the National Cancer Institute 19830601

Title: Slapikoff SA, et al. Comparison of toxicity and mutagenicity of methylnitrosourea, methylnitronitrosoguanidine and ICR-191 among human lymphoblast lines. Mutat Res. 1980 May;70(3):365-71.

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