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1839-18-5,MFCD00037925
Catalog No.:AA003369

1839-18-5 | 2-Chloroadenine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$7.00   $5.00
- +
5g
97%
in stock  
$16.00   $11.00
- +
10g
97%
in stock  
$31.00   $22.00
- +
25g
97%
in stock  
$75.00   $53.00
- +
100g
97%
in stock  
$298.00   $209.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003369
Chemical Name:
2-Chloroadenine
CAS Number:
1839-18-5
Molecular Formula:
C5H4ClN5
Molecular Weight:
169.5718
MDL Number:
MFCD00037925
SMILES:
Clc1nc(N)c2c(n1)nc[nH]2
NSC Number:
7362
Properties
Properties
 
BP:
315.2°C at 760 mmHg  
Form:
Solid  
MP:
>300°C(dec)  
Refractive Index:
1.6110 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
154  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
XLogP3:
0.4  

Literature

Title: Correlation of the time course of development and decay of tolerance to morphine with alterations in sodium pump protein isoform abundance.

Journal: Biochemical pharmacology 20100401

Title: Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: possible involvement of adenosinergic mechanism.

Journal: Epilepsy research 20080101

Title: [Synthesis of 2-chloro-2'-deoxyadenosine by microbiological transglycosylation using a recombinant Escherichia coli strain].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20080101

Title: New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile.

Journal: Purinergic signalling 20070901

Title: Age-related changes in ischemic tolerance in male and female mouse hearts.

Journal: Journal of molecular and cellular cardiology 20050201

Title: Application of population pharmacokinetics to cladribine.

Journal: BMC pharmacology 20050101

Title: Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides.

Journal: Nucleosides, nucleotides & nucleic acids 20050101

Title: Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates.

Journal: Biochemistry 20040928

Title: Cytotoxicity and pharmacokinetics of cladribine metabolite, 2-chloroadenine in patients with leukemia.

Journal: Cancer letters 20040716

Title: Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography; Identification of a novel metabolite of 2-chlorodeoxyadenosine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615

Title: Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids.

Journal: Nucleosides, nucleotides & nucleic acids 20031201

Title: Oligonucleotides incorporating 8-aza-7-deazapurines: synthesis and base pairing of nucleosides with nitrogen-8 as a glycosylation position.

Journal: Organic & biomolecular chemistry 20030607

Title: 3'-deoxyribofuranose derivatives of 1-deaza and 3-deaza-adenosine and their activity as adenosine deaminase inhibitors.

Journal: Nucleosides, nucleotides & nucleic acids 20010101

Title: Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.

Journal: Biochemical pharmacology 19951109

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