Home Amines 55-86-7
55-86-7,MFCD00012517
Catalog No.:AA00336P

55-86-7 | Bis(2-chloroethyl)-N-methylamine hydrochloride

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00336P
Chemical Name:
Bis(2-chloroethyl)-N-methylamine hydrochloride
CAS Number:
55-86-7
Molecular Formula:
C5H12Cl3N
Molecular Weight:
192.5145
MDL Number:
MFCD00012517
SMILES:
ClCCN(CCCl)C.Cl
NSC Number:
762
UN Number:
2811
Properties
Properties
 
BP:
315.95°C (rough estimate)  
Form:
Solid  
MP:
108-111 °C(lit.)  
Refractive Index:
1.6300 (estimate)  
Solubility:
H2O: very soluble  
Stability:
Hygroscopic  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
43.7  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  

Literature

Title: Efficacy of anti-inflammatory, antibiotic and pleiotropic agents in reversing nitrogen mustard-induced injury in ex vivo cultured rabbit cornea.

Journal: Toxicology letters 20180901

Title: Formation and degradation of nitrogen mustard-induced MGMT-DNA crosslinking in 16HBE cells.

Journal: Toxicology 20170815

Title: Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170501

Title: Mustard vesicants alter expression of the endocannabinoid system in mouse skin.

Journal: Toxicology and applied pharmacology 20160715

Title: Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis.

Journal: American journal of respiratory cell and molecular biology 20160301

Title: Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.

Journal: Toxicology letters 20160226

Title: Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-Associated Protein 1 (Mrp1).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160101

Title: Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction.

Journal: Chemical research in toxicology 20151116

Title: Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20151101

Title: Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators.

Journal: Toxicology letters 20150615

Title: Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

Journal: Toxicology 20140605

Title: Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling.

Journal: Chemical research in toxicology 20140121

Title: Synthesis and analysis of activity of a potential anti-melanoma prodrug with a hydrazine linker.

Journal: European journal of medicinal chemistry 20140101

Title: Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.

Journal: Chemico-biological interactions 20131205

Title: The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard.

Journal: Toxicology and applied pharmacology 20131015

Title: Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.

Journal: Toxicology 20130915

Title: Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis.

Journal: Journal of biochemical and molecular toxicology 20130601

Title: Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor.

Journal: Toxicology and applied pharmacology 20121215

Title: Incidence, predictors and significance of severe toxicity in patients with human immunodeficiency virus-associated Hodgkin lymphoma.

Journal: Leukemia & lymphoma 20121201

Title: Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework.

Journal: Journal of enzyme inhibition and medicinal chemistry 20121001

Title: Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.

Journal: Toxicology and applied pharmacology 20121001

Title: Synthesis and antitumor activity of formononetin nitrogen mustard derivatives.

Journal: European journal of medicinal chemistry 20120801

Title: The mechanism of guanine alkylation by nitrogen mustards: a computational study.

Journal: The Journal of organic chemistry 20120720

Title: Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity.

Journal: The Journal of surgical research 20120601

Title: Increased expression of VDAC1 sensitizes carcinoma cells to apoptosis induced by DNA cross-linking agents.

Journal: Biochemical pharmacology 20120501

Title: Persistent genomic instability in peripheral blood lymphocytes from Hodgkin lymphoma survivors.

Journal: Environmental and molecular mutagenesis 20120501

Title: Characterization and study of piperazinium salts, degradation products of nitrogen mustards by nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20120302

Title: Topical nitrogen mustard therapy in patients with Langerhans cell histiocytosis.

Journal: The British journal of dermatology 20120301

Title: Common stem: -mustine.

Journal: Prescrire international 20120301

Title: Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option.

Journal: International journal of radiation oncology, biology, physics 20120201

Title: DNA interstrand cross-linking agents and their chemotherapeutic potential.

Journal: Current medicinal chemistry 20120101

Title: New thymine-based derivative of nitrogen mustards.

Journal: Nucleosides, nucleotides & nucleic acids 20120101

Title: Mechlorethamine (NTG) effects on the erythrocytic and leukocytic blood parameters during experimentally induced pleuritis in rats.

Journal: Pharmacological reports : PR 20120101

Title: Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

Journal: Journal of the American Chemical Society 20111207

Title: Long-term follow-up analysis of HD9601 trial comparing ABVD versus Stanford V versus MOPP/EBV/CAD in patients with newly diagnosed advanced-stage Hodgkin's lymphoma: a study from the Intergruppo Italiano Linfomi.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111110

Title: Insight into hydrolytic reaction of N-acetylated L-histidylglycine dipeptide with novel mechlorethamine platinum(II) complex. NMR and DFT study of the hydrolytic reaction.

Journal: Dalton transactions (Cambridge, England : 2003) 20110928

Title: Array of Love-wave sensors based on quartz/Novolac to detect CWA simulants.

Journal: Talanta 20110915

Title: High-throughput sample preparation and simultaneous column regeneration liquid chromatography-tandem mass spectrometry method for determination of nitrogen mustard metabolites in human urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110815

Title: Mechlorethamine-induced DNA-protein cross-linking in human fibrosarcoma (HT1080) cells.

Journal: Journal of proteome research 20110603

Title: Determination of nitrogen mustard hydrolysis products in rat urine samples using GC-MS.

Journal: Journal of chromatographic science 20110501

Title: The Stanford University experience with conventional-dose, total skin electron-beam therapy in the treatment of generalized patch or plaque (T2) and tumor (T3) mycosis fungoides.

Journal: Archives of dermatology 20110501

Title: First use of intravenous chemotherapy cancer treatment: rectifying the record.

Journal: Journal of the American College of Surgeons 20110301

Title: Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries.

Journal: Biomaterials 20110201

Title: Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard.

Journal: Toxicology and applied pharmacology 20110101

Title: Estimation of the action of three different mechlorethamine doses on biochemical parameters during experimentally induced pleuritis in rats.

Journal: Pharmacological reports : PR 20110101

Title: HPLC-UV, MALDI-TOF-MS and ESI-MS/MS analysis of the mechlorethamine DNA crosslink at a cytosine-cytosine mismatch pair.

Journal: PloS one 20110101

Title: Nitrogen mustard hydrochloride.

Journal: Report on carcinogens : carcinogen profiles 20110101

Title: Alkylating antitumor drug mechlorethamine conceals a structured PrP domain and inhibits in vitro prion amplification.

Journal: Journal of toxicology and environmental health. Part A 20110101

Title: The effect of Nitrogen Mustard on the enzymatic antioxidant defense of rat brain tissue and the therapeutic value of proanthocyanidin.

Journal: Turkish neurosurgery 20110101

Title: The effect of sulfur mustard and nitrogen mustard on corneal collagen degradation induced by the enzyme collagenase.

Journal: Cutaneous and ocular toxicology 20101201

Title: Accelerated aging of intervertebral discs in a mouse model of progeria.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20101201

Title: Comparison between L-CHOP and an L-CHOP protocol with interposed treatments of CCNU and MOPP (L-CHOP-CCNU-MOPP) for lymphoma in dogs.

Journal: Veterinary and comparative oncology 20101201

Title: Treatment of 2,453 acne vulgaris patients aged 12-17 years with the fixed-dose adapalene-benzoyl peroxide combination topical gel: efficacy and safety.

Journal: Journal of drugs in dermatology : JDD 20101101

Title: Specific nail alterations in cutaneous T-cell lymphoma: successful treatment with topical mechlorethamine.

Journal: Archives of dermatology 20101101

Title: Nitrogen and sulphur mustard induced histopathological observations in mouse visceral organs.

Journal: Journal of environmental biology 20101101

Title: Hodgkin's lymphoma: Richter's transformation of chronic lymphocytic leukemia involving the liver.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010

Title: Mutagenesis of nucleophilic residues near the orthosteric binding pocket of M1 and M2 muscarinic receptors: effect on the binding of nitrogen mustard analogs of acetylcholine and McN-A-343.

Journal: Molecular pharmacology 20101001

Title: Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease.

Journal: Journal of pediatric hematology/oncology 20101001

Title: Doxycycline hydrogels as a potential therapy for ocular vesicant injury.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20101001

Title: Cardiopulmonary toxicity of different chemoradiotherapy combined regimens for Hodgkin's disease.

Journal: Anticancer research 20101001

Title: Comparative toxic effect of nitrogen mustards (HN-1, HN-2, and HN-3) and sulfur mustard on hematological and biochemical variables and their protection by DRDE-07 and its analogues.

Journal: International journal of toxicology 20100701

Title: Innovative therapy of cutaneous T-cell lymphoma: beyond psoralen and ultraviolet light and nitrogen mustard.

Journal: Dermatologic clinics 20100701

Title: The influence of chromatin structure on DNA damage induced by nitrogen mustard and cisplatin analogues.

Journal: Chemical biology & drug design 20100601

Title: Kin3 protein, a NIMA-related kinase of Saccharomyces cerevisiae, is involved in DNA adduct damage response.

Journal: Cell cycle (Georgetown, Tex.) 20100601

Title: Lipomatosis: an unusual side-effect of cytotoxic chemotherapy?

Journal: Acta dermato-venereologica 20100501

Title: Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard.

Journal: Journal of chromatography. A 20100423

Title: Aziridinium ion ring formation from nitrogen mustards: mechanistic insights from ab initio dynamics.

Journal: The journal of physical chemistry. A 20100408

Title: Comparative study of two mechlorethamine, vincristine, procarbazine, and prednisone derived chemotherapeutic protocols for the management of pediatric Hodgkin lymphoma (HL): single-center 5-year experience.

Journal: Leukemia & lymphoma 20100401

Title: The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkin's lymphoma.

Journal: European journal of haematology 20100301

Title: Immune thrombocytopenic purpura at the diagnosis of Hodgkin disease.

Journal: Acta clinica Belgica 20100101

Title: Hypopigmented macules and patches on the extremities of a teenager.

Journal: Pediatric dermatology 20100101

Title: Long-term follow-up of survival in Hodgkin's lymphoma.

Journal: The New England journal of medicine 20091210

Title: Pragmatic classification of superficial neoplastic colorectal lesions.

Journal: Gastrointestinal endoscopy 20091201

Title: Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy.

Journal: International journal of radiation oncology, biology, physics 20091201

Title: Cutaneous T-cell lymphoma: a review of current therapies and the future therapeutic implications of chemokine biology.

Journal: Journal of drugs in dermatology : JDD 20091201

Title: The effect of nitrogen mustard on the rat brain and the therapeutic value of proanthocyanidin.

Journal: Turkish neurosurgery 20091001

Title: Radiation therapy compared with chemotherapy for consolidation of chemotherapy-induced remission of advanced Hodgkin lymphoma: a study by the Eastern Co-operative Oncology Group (E1476) with >20 years follow-up.

Journal: Leukemia & lymphoma 20091001

Title: Topical chlormethine hydrochloride causing bullous reaction.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090901

Title: DRDE-07 and its analogues as promising cytoprotectants to nitrogen mustard (HN-2)--an alkylating anticancer and chemical warfare agent.

Journal: Toxicology letters 20090810

Title: Synthesis and cytotoxic activity of novel amidine analogues of bis(2-chloroethyl)amine.

Journal: Archiv der Pharmazie 20090801

Title: [Nasopharyngeal carcinoma in sub-Saharan Africa: a tribute to Mr. Peter Clifford].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090801

Title: Comparison between hybrid MOPPABV and ABVD chemotherapy protocols for Hodgkin's lymphoma in public hospitals of the largest South American city: a retrospective 14-year study.

Journal: Annals of hematology 20090701

Title: Acute promyelocytic leukemia after Stanford V plus radiotherapy for advanced Hodgkin lymphoma.

Journal: Leukemia & lymphoma 20090701

Title: Development of spray deposition/MALDI-TOFMS and its application to the rapid screening of hydrolysis products derived from nitrogen mustards.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090701

Title: Bone mineral density, growth, and thyroid function in long-term survivors of pediatric Hodgkin's lymphoma treated with chemotherapy only.

Journal: The Journal of clinical endocrinology and metabolism 20090601

Title: DNA repair modulates the vulnerability of the developing brain to alkylating agents.

Journal: DNA repair 20090301

Title: Mechlorethamine, procarbazine and prednisone for the treatment of resistant lymphoma in dogs.

Journal: Veterinary and comparative oncology 20090301

Title: A clinically relevant in vitro model for evaluating the effects of aerosolized vesicants.

Journal: Toxicology letters 20090225

Title: Generation of DNA interstrand cross-links by post-synthetic reductive amination.

Journal: Organic letters 20090205

Title: The Stanford V regimen is effective in patients with good risk Hodgkin lymphoma but radiotherapy is a necessary component.

Journal: British journal of haematology 20090201

Title: Cardiopulmonary response to exercise in patients with different degrees of lung toxicity after radio-chemotherapy for Hodgkin's disease.

Journal: Anticancer research 20090201

Title: [Concomitant pulmonary Langerhans cell histiocytosis and malignant lymphoma: report of two cases].

Journal: Journal de radiologie 20090101

Title: Efficacy of combination chemotherapy for treatment of gastrointestinal lymphoma in dogs.

Journal: Journal of veterinary internal medicine 20090101

Title: Influence of cyclophosphamide and its metabolic products on the activity of peritoneal macrophages in mice.

Journal: Pharmacological reports : PR 20090101

Title: Asparaginase and MOPP treatment of dogs with lymphoma.

Journal: Journal of veterinary internal medicine 20090101

Title: [Multivariate analysis of risk of cardiac complications in Hodgkin's lymphoma].

Journal: Voprosy onkologii 20090101

Title: Standard therapy of advanced Hodgkin lymphoma.

Journal: Hematology. American Society of Hematology. Education Program 20090101

Title: Breast cancer after treatment of Hodgkin's lymphoma: general review.

Journal: International journal of radiation oncology, biology, physics 20081201

Title: Vanishing bile duct syndrome and Hodgkin disease: a case series and review of the literature.

Journal: Journal of pediatric hematology/oncology 20081201

Title: Comparison of toxicity of selected mustard agents by percutaneous and subcutaneous routes.

Journal: Indian journal of experimental biology 20081201

Title: Prognostic factors in children with Hodgkin disease.

Journal: Pediatric blood & cancer 20081101

Title: Clinicopathologic features and treatment outcomes in Woringer-Kolopp disease.

Journal: Journal of the American Academy of Dermatology 20081001

Title: Stability of the nitrogen mustard mechlorethamine in novel formulations for dermatological use.

Journal: International journal of pharmaceutics 20081001

Title: Treatment of Hodgkin lymphoma: the past, present, and future.

Journal: Nature clinical practice. Oncology 20080901

Title: [Autologous hematopoietic stem cell transplantation followed by oral bexarotene in a patient with advanced mycosis fungoides].

Journal: Actas dermo-sifiliograficas 20080901

Title: Ovarian function preservation in patients under chemotherapy treatment.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080901

Title: [Combined-modality therapy for 150 cases of early-stage Hodgkin's lymphoma].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080801

Title: Paraspinal synovial sarcoma as an unusual postradiation complication in pediatric abdominal neuroblastoma.

Journal: Journal of pediatric hematology/oncology 20080701

Title: Single-molecule detection of nitrogen mustards by covalent reaction within a protein nanopore.

Journal: Journal of the American Chemical Society 20080528

Title: Modifications and insights into a method for the analysis of the nitrogen mustard mechlorethamine by high-performance liquid chromatography.

Journal: Analytica chimica acta 20080526

Title: Results of treatment of 112 cases of primary CNS lymphoma.

Journal: Japanese journal of clinical oncology 20080501

Title: [Phyllanthus urinaria extract promotes N-cadherin expression in nitrogen mustard-disrupted testicular tissues in vivo].

Journal: Zhonghua nan ke xue = National journal of andrology 20080501

Title: A 4-month-old boy with diaper dermatitis. Langerhans cell histiocytosis.

Journal: Pediatric annals 20080401

Title: Systemic chemotherapy for cancer: from weapon to treatment.

Journal: The Lancet. Oncology 20080301

Title: Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease.

Journal: The New England journal of medicine 20080214

Title: Treatment-related risk factors for premature menopause following Hodgkin lymphoma.

Journal: Blood 20080101

Title: Development of a liquid chromatography-multiple reaction monitoring procedure for concurrent verification of exposure to different forms of mustard agents.

Journal: Journal of analytical toxicology 20080101

Title: Mycosis fungoides in a lung transplant recipient with advanced ciclosporin nephropathy: management with mechlorethamine and subsequent renal transplantation.

Journal: Dermatology (Basel, Switzerland) 20080101

Title: [Features of clinical course of combination chemotherapy for liver involvement in Hodgkin's disease].

Journal: Voprosy onkologii 20080101

Title: Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells.

Journal: Cutaneous and ocular toxicology 20080101

Title: The new analogues of nitrogen mustard with one, two or three 2-chloroethylamino fragments. Reactions with nucleophiles.

Journal: Acta poloniae pharmaceutica 20080101

Title: [Use of risk-adapted programs of treatment of Hodgkin's disease in children and adolescents].

Journal: Voprosy onkologii 20080101

Title: Inhibin B is superior to FSH as a serum marker for spermatogenesis in men treated for Hodgkin's lymphoma with chemotherapy during childhood.

Journal: Human reproduction (Oxford, England) 20071201

Title: [Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20071201

Title: [Chlormethine (Caryolysine), carmustine (Bicnu)].

Journal: Annales de dermatologie et de venereologie 20071201

Title: Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease.

Journal: The New England journal of medicine 20071108

Title: Tissue injury by hot fluid containing nitrogen mustard.

Journal: Burns : journal of the International Society for Burn Injuries 20071101

Title: Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin's lymphoma during childhood.

Journal: The Journal of clinical endocrinology and metabolism 20071001

Title: Treatment planning and delivery of involved field radiotherapy in advanced Hodgkin's disease: results from a questionnaire-based audit for the UK Stanford V regimen vs ABVD clinical trial quality assurance programme (ISRCTN 64141244).

Journal: The British journal of radiology 20071001

Title: Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard.

Journal: Toxicology letters 20070910

Title: Impact of positive positron emission tomography on prediction of freedom from progression after Stanford V chemotherapy in Hodgkin's disease.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901

Title: Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats.

Journal: Research in veterinary science 20070801

Title: Will BEACOPP be the standard for high risk Hodgkin lymphoma patients in advanced stages?

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070801

Title: Mycosis fungoides.

Journal: Dermatology nursing 20070801

Title: Salvage therapy and late neurotoxicity in patients with recurrent primary CNS lymphoma treated with a modified ProMACE-MOPP hybrid regimen.

Journal: Leukemia & lymphoma 20070601

Title: Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance.

Journal: Cancer research 20070501

Title: Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity.

Journal: Toxicology and industrial health 20070501

Title: [Our experiences in treating patients with Hodgkin disease in the last decade].

Journal: Orvosi hetilap 20070415

Title: Bifunctional alkylating agent-induced p53 and nonclassical nuclear factor kappaB responses and cell death are altered by caffeic acid phenethyl ester: a potential role for antioxidant/electrophilic response-element signaling.

Journal: The Journal of pharmacology and experimental therapeutics 20070401

Title: Ovarian function after cancer treatment in young women affected by Hodgkin disease (HD).

Journal: Hematology (Amsterdam, Netherlands) 20070401

Title: Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.

Journal: Cancer science 20070301

Title: Hodgkin lymphoma among patients infected with HIV in post-HAART era.

Journal: Clinical lymphoma & myeloma 20070301

Title: Chemosensitivity of primary human fibroblasts with defective unhooking of DNA interstrand cross-links.

Journal: Experimental cell research 20070215

Title: Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma.

Journal: International journal of clinical oncology 20070201

Title: Systemic monotherapy vs combination therapy for CTCL: rationale and future strategies.

Journal: Oncology (Williston Park, N.Y.) 20070201

Title: Molecular mechanism of nitrogen mustard induced leukocyte(s) chemotaxis.

Journal: Medical hypotheses 20070101

Title: Involved-field radiotherapy for patients in partial remission after chemotherapy for advanced Hodgkin's lymphoma.

Journal: International journal of radiation oncology, biology, physics 20070101

Title: Cytoskeleton vimentin disruption of mouse sertoli cells injured by nitrogen mustard in vitro.

Journal: Journal of andrology 20070101

Title: Topical nitrogen mustard for the treatment of granulomatous slack skin.

Journal: American journal of clinical dermatology 20070101

Title: Survival improvement of young patients, aged 16-23, with Hodgkin lymphoma (HL) during the last three decades.

Journal: Anticancer research 20070101

Title: [Evolution in 18F-FDG-PET of a case of Hodgkin disease, nodular sclerosis variety, after treatment and autotrasplant].

Journal: Revista espanola de medicina nuclear 20070101

Title: Ocular effects of exposure to industrial chemicals: clinical management and proteomic approaches to damage assessment.

Journal: Cutaneous and ocular toxicology 20070101

Title: Down-regulation of HER-2 expression in human breast cancer cell HBC-4 and ZR75-1 by nitrogen-mustard-N-oxide.

Journal: The Kobe journal of medical sciences 20070101

Title: Alkylation activity and molecular properties of two antineoplastic agents that utilise indometacin and a conjugate of aspirin with 2-aminonicotinic acid to transport nitrogen mustard groups.

Journal: Drugs in R&D 20070101

Title: Survival and late effects in children with Hodgkin's lymphoma treated with MOPP/ABV and low-dose, extended-field irradiation.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061220

Title: Eruptive cherry angiomas associated with vitiligo: provoked by topical nitrogen mustard?

Journal: The Journal of dermatology 20061201

Title: Treatment of cutaneous T-cell lymphoma/mycosis fungoides.

Journal: Dermatology nursing 20061201

Title: Drosophila homologs of FANCD2 and FANCL function in DNA repair.

Journal: DNA repair 20061108

Title: Rational design, synthesis and in vitro evaluation of three new alkylating steroidal esters.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20061101

Title: Genotoxicants target distinct molecular networks in neonatal neurons.

Journal: Environmental health perspectives 20061101

Title: Sequential multidrug chemotherapy (CHOP-VA-MB) in patients with high-grade non-Hodgkin's lymphoma--a 20-year follow-up.

Journal: Annals of hematology 20061001

Title: Long-term results of autologous stem cell transplantation for primary refractory or relapsed Hodgkin's lymphoma.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20061001

Title: Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20060901

Title: [Feasibility study of application of international prognostic score on prediction of prognosis for advanced Hodgkin's lymphoma].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20060801

Title: Determination of nitrogen mustard hydrolysis products, ethanolamines by gas chromatography-mass spectrometry after tert-butyldimethylsilyl derivatization.

Journal: Journal of chromatography. A 20060728

Title: Combined-modality therapy for clinical stage I or II Hodgkin's lymphoma: long-term results of the European Organisation for Research and Treatment of Cancer H7 randomized controlled trials.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060701

Title: Long-term results and competing risk analysis of the H89 trial in patients with advanced-stage Hodgkin lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte (GELA).

Journal: Blood 20060615

Title: Topical mechlorethamine and clobetasol in multifocal primary cutaneous marginal zone-B cell lymphoma.

Journal: The British journal of dermatology 20060601

Title: Hodgkin's lymphoma in adolescents.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601

Title: POG 8625: a randomized trial comparing chemotherapy with chemoradiotherapy for children and adolescents with Stages I, IIA, IIIA1 Hodgkin Disease: a report from the Children's Oncology Group.

Journal: Journal of pediatric hematology/oncology 20060601

Title: New mustard-linked 2-aryl-bis-benzimidazoles with anti-proliferative activity.

Journal: Organic & biomolecular chemistry 20060407

Title: [Clinical analysis of reactive thymic hyperplasia following chemotherapy for childhood malignant lymphoma].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20060401

Title: [Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060301

Title: MOPPEBVCAD chemotherapy with limited and conditioned radiotherapy in advanced Hodgkin's lymphoma: 10-year results, late toxicity, and second tumors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060115

Title: Screening of nitrogen mustards and their degradation products in water and decontamination solution by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20060113

Title: Bullous reaction to topical methchlorethamine in mycosis fungoides.

Journal: Journal of drugs in dermatology : JDD 20060101

Title: Effect of nitrogen mustard, a vesicant agent, on lymphocyte energy metabolism.

Journal: Clinical chemistry and laboratory medicine 20060101

Title: [Ten-year outcomes of lymphogranulomatosis treatment according to the protocol MOPP-ABVD+radiotherapy].

Journal: Terapevticheskii arkhiv 20060101

Title: Mycosis fungoides with tinea pseudoimbricata owing to Trichophyton rubrum infection.

Journal: Journal of cutaneous medicine and surgery 20060101

Title: ABVD versus modified stanford V versus MOPPEBVCAD with optional and limited radiotherapy in intermediate- and advanced-stage Hodgkin's lymphoma: final results of a multicenter randomized trial by the Intergruppo Italiano Linfomi.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051220

Title: Long-term follow-up of salvage radiotherapy in Hodgkin's lymphoma after chemotherapy failure.

Journal: International journal of radiation oncology, biology, physics 20051201

Title: Benign pleural schwannoma secondary to radiotherapy for Hodgkin disease.

Journal: American journal of clinical oncology 20051201

Title: New treatment options have changed the survival of patients with follicular lymphoma.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051120

Title: Quality control of involved-field radiotherapy in patients with advanced Hodgkin's lymphoma (EORTC 20884).

Journal: International journal of radiation oncology, biology, physics 20051115

Title: Design and synthesis of a DNA-crosslinking azinomycin analogue.

Journal: Organic & biomolecular chemistry 20051007

Title: S100P is selectively upregulated in tumor cell lines challenged with DNA cross-linking agents.

Journal: Leukemia research 20051001

Title: Analysis of the nitrogen mustard mechlorethamine in topical pharmaceutical preparations by high-performance liquid chromatography.

Journal: Journal of chromatography. A 20050902

Title: Gemcitabine-induced radiation recall dermatitis in a patient with resistant Hodgkin lymphoma.

Journal: American journal of hematology 20050901

Title: Treatment of early-stage mycosis fungoides with twice-weekly applications of mechlorethamine and topical corticosteroids: a prospective study.

Journal: Archives of dermatology 20050901

Title: Late non-neoplastic events in patients with aggressive non-Hodgkin's lymphoma in four randomized European Organisation for Research and Treatment of Cancer trials.

Journal: Clinical lymphoma & myeloma 20050901

Title: [Observation on the 78th meeting of the Japanese Society for Hansen's Disease].

Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20050901

Title: [Local treatments of cutaneous T-cell lymphomas].

Journal: Annales de dermatologie et de venereologie 20050901

Title: Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.

Journal: Annals of hematology 20050701

Title: Aquatic toxicity of nitrogen mustard to Ceriodaphina dubia, Daphnia magna, and Pimephales promelas.

Journal: Ecotoxicology and environmental safety 20050601

Title: Secondary transitional cell carcinoma and nitrogen mustard treatment.

Journal: Urology 20050601

Title: On-matrix derivatisation-extraction of precursors of nitrogen- and sulfur-mustards for verification of chemical weapons convention.

Journal: Journal of chromatography. A 20050527

Title: Overexpression of GSTA2 protects against cell cycle arrest and apoptosis induced by the DNA inter-strand crosslinking nitrogen mustard, mechlorethamine.

Journal: Journal of cellular biochemistry 20050515

Title: Cytokinetics and mechanism of action of AKO4: a novel nitrogen mustard targeted to bcr-abl.

Journal: Leukemia research 20050501

Title: Treatment of ocular tissues exposed to nitrogen mustard: beneficial effect of zinc desferrioxamine combined with steroids.

Journal: Investigative ophthalmology & visual science 20050501

Title: Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease.

Journal: Cancer genetics and cytogenetics 20050501

Title: Survival in Hodgkin's disease patients--report of 25 years of experience at the Milan Cancer Institute.

Journal: European journal of cancer (Oxford, England : 1990) 20050501

Title: Nitrogen mustard- and half-mustard-induced damage in Escherichia coli requires different DNA repair pathways.

Journal: Mutation research 20050404

Title: Footprinting the 'essential regulatory region' of the retinoblastoma gene promoter in intact human cells.

Journal: The international journal of biochemistry & cell biology 20050301

Title: Perspectives of the management of childhood lymphoma: experience at Tygerberg Hospital, Western Cape, South Africa.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201

Title: [Primary treatment of advanced Hodgkin's disease].

Journal: Orvosi hetilap 20050130

Title: A chick model for the mechanisms of mustard gas neurobehavioral teratogenicity.

Journal: Neurotoxicology and teratology 20050101

Title: Evaluation of protective ointments used against dermal effects of nitrogen mustard, a vesicant warfare agent.

Journal: Military medicine 20050101

Title: Targeting and regulation of the HER-2/neu oncogene promoter with bis-peptide nucleic acids.

Journal: Oligonucleotides 20050101

Title: Gas chromatography-mass spectrometry analysis of trifluoroacetyl derivatives of precursors of nitrogen and sulfur mustards for verification of chemical weapons convention.

Journal: Journal of chromatography. A 20041203

Title: Milia in regressing plaques of mycosis fungoides: provoked by topical nitrogen mustard or not?

Journal: International journal of dermatology 20041201

Title: Hypermutability in a Drosophila model for multiple endocrine neoplasia type 1.

Journal: Human molecular genetics 20041015

Title: Flanking sequences modulate diepoxide and mustard cross-linking efficiencies at the 5'-GNC site.

Journal: Chemical research in toxicology 20040801

Title: Treatment of pediatric Hodgkin disease avoiding radiotherapy: excellent outcome with the Rotterdam-HD-84-protocol.

Journal: Pediatric blood & cancer 20040701

Title: Combination chemotherapy plus low-dose involved-field radiotherapy for early clinical stage Hodgkin's lymphoma.

Journal: International journal of radiation oncology, biology, physics 20040701

Title: Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.

Journal: Chemical research in toxicology 20040701

Title: Efficacy of a modified Stanford V regimen in patients with advanced Hodgkin's lymphoma.

Journal: Haematologica 20040601

Title: Genomic and phylogenetic footprinting at the epsilon-globin silencer region in intact human cells.

Journal: Biochimica et biophysica acta 20040525

Title: Chloroalkyl piperazine and nitrogen mustard porphyrins: synthesis and anticancer activity.

Journal: Bioorganic & medicinal chemistry 20040501

Title: A large-scale screen for mutagen-sensitive loci in Drosophila.

Journal: Genetics 20040501

Title: Dual purpose: some cancer therapies used to treat autoimmune diseases.

Journal: Journal of the National Cancer Institute 20040421

Title: Decreasing the number of MOPP courses reduces gonadal damage in survivors of childhood Hodgkin disease.

Journal: Pediatric blood & cancer 20040301

Title: Pediatric Hodgkin's disease.

Journal: The Journal of the Kentucky Medical Association 20040301

Title: Sticky DNA formation in vivo alters the plasmid dimer/monomer ratio.

Journal: The Journal of biological chemistry 20040220

Title: Comparison of MOPP versus ABVD as salvage therapy in patients who relapse after radiation therapy alone for Hodgkin's disease.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040201

Title: Therapeutic options in patients with lymphoma and severe liver dysfunction.

Journal: Mayo Clinic proceedings 20040201

Title: What is the treatment of choice for advanced-stage Hodgkin's lymphoma: ABVD, Stanford V, or BEACOPP?

Journal: Current hematology reports 20040101

Title: Secondary axillary node carcinoma following treatment of Hodgkin's disease.

Journal: The breast journal 20040101

Title: Quantitation of biomarkers of exposure to nitrogen mustards in urine from rats dosed with nitrogen mustards and from an unexposed human population.

Journal: Journal of analytical toxicology 20040101

Title: Stanford V regimen plus consolidative radiotherapy is an effective therapeutic program for bulky or advanced-stage Hodgkin's disease.

Journal: Acta haematologica 20040101

Title: [Over 30-year experience of Polish Pediatric Leukemia/Lymphoma Study Group for treatment of Hodgkin's disease in children and adolescents: improvement curability and decrease of serious complications].

Journal: Przeglad lekarski 20040101

Title: Nitrogen mustard hydrochloride.

Journal: Report on carcinogens : carcinogen profiles 20040101

Title: Impact of chest wall and lung invasion on outcome of stage I-II Hodgkin's lymphoma after combined modality therapy.

Journal: International journal of radiation oncology, biology, physics 20031201

Title: Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation.

Journal: Bone marrow transplantation 20031201

Title: The treatment of adults with medulloblastoma: a prospective study.

Journal: International journal of radiation oncology, biology, physics 20031101

Title: [Second malignancies following Hodgkin's disease treatment in Tunisia. Retrospective study of 26 cases observed at the institute Salah-Azaïz].

Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20031001

Title: Old wine in new bottles: reviving old therapies for alopecia areata using rodent models.

Journal: The journal of investigative dermatology. Symposium proceedings 20031001

Title: [Hematologic tumors].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20031001

Title: Radiotherapy for advanced Hodgkin's disease.

Journal: The New England journal of medicine 20030918

Title: Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study.

Journal: Journal of the American Academy of Dermatology 20030801

Title: The protective and therapeutic effects of zinc chloride and desferrioxamine on skin exposed to nitrogen mustard.

Journal: Military medicine 20030801

Title: Radiation therapy in the treatment of Hodgkin's disease--do you see what I see?

Journal: Journal of the National Cancer Institute 20030702

Title: Analysis of treatment results in advanced Hodgkin's disease: the case for adjuvant radiotherapy.

Journal: International journal of radiation oncology, biology, physics 20030701

Title: Injury induced by chemical warfare agents: characterization and treatment of ocular tissues exposed to nitrogen mustard.

Journal: Investigative ophthalmology & visual science 20030701

Title: Revascularization for acute coronary occlusion in a young woman following radiation.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20030701

Title: High-dose therapy and autologous stem-cell transplantation versus conventional therapy for patients with advanced Hodgkin's lymphoma responding to front-line therapy.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615

Title: Involved-field radiotherapy for advanced Hodgkin's lymphoma.

Journal: The New England journal of medicine 20030612

Title: [Hodgkin's disease manifesting as paraneoplastic limbic encephalitis].

Journal: La Revue de medecine interne 20030401

Title: Differential diagnosis of Fanconi anemia by nitrogen mustard and diepoxybutane.

Journal: Annals of hematology 20030401

Title: Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study.

Journal: Blood 20030301

Title: Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes.

Journal: The Journal of investigative dermatology 20030301

Title: Advanced Hodgkin's disease: ABVD is better, yet is not good enough!

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030215

Title: Randomized comparison of ABVD and MOPP/ABV hybrid for the treatment of advanced Hodgkin's disease: report of an intergroup trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030215

Title: Topical nitrogen mustard in the management of mycosis fungoides: update of the Stanford experience.

Journal: Archives of dermatology 20030201

Title: Quantitative determination of the hydrolysis products of nitrogen mustards in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Journal of analytical toxicology 20030101

Title: Synthesis and in vivo biodisposition of [14C]-quaternary ammonium-melphalan conjugate, a potential cartilage-targeted alkylating drug.

Journal: Bioconjugate chemistry 20030101

Title: Topical nitrogen mustard ointment with occlusion for Langerhans' cell histiocytosis of the scalp.

Journal: The Journal of dermatological treatment 20030101

Title: Impaired healing of nitrogen mustard wounds in CXCR2 null mice.

Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20030101

Title: Cutaneous granulomas as the first manifestation of Hodgkin's disease.

Journal: European journal of dermatology : EJD 20030101

Title: An elevated serum beta-2-microglobulin level is an adverse prognostic factor for overall survival in patients with early-stage Hodgkin disease.

Journal: Cancer 20021215

Title: Pathways of reductive fragmentation of heterocyclic nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine.

Journal: Radiation research 20021201

Title: Serum levels of soluble CD30 improve International Prognostic Score in predicting the outcome of advanced Hodgkin's lymphoma.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021201

Title: Postpneumonectomy-like syndrome after chemoradiation therapy for lymphoma.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021201

Title: [Psoriasis of the scalp].

Journal: Annales de dermatologie et de venereologie 20021201

Title: Evaluation of a 1-h exposure time to mechlorethamine in patients undergoing topical treatment.

Journal: The British journal of dermatology 20021101

Title: Long-term results of conventional-dose salvage chemotherapy in patients with refractory and relapsed Hodgkin's disease (Croatian experience).

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021001

Title: Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection.

Journal: Blood 20020915

Title: The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient mice.

Journal: Oncogene 20020829

Title: Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation.

Journal: British journal of haematology 20020701

Title: Pulmonary toxicity secondary to procarbazine.

Journal: American journal of clinical oncology 20020401

Title: European Organization for Research and Treatment of Cancer and Groupe d'Etude des Lymphomes de l'Adulte very favorable and favorable, lymphocyte-predominant Hodgkin disease.

Journal: Cancer 20020315

Title: Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin.

Journal: Archives of toxicology 20020301

Title: Topical treatment with povidone iodine reduces nitrogen mustard-induced skin collagenolytic activity.

Journal: Archives of toxicology 20020301

Title: Subdiaphragmatic Hodgkin's disease: the University of Florida experience.

Journal: International journal of radiation oncology, biology, physics 20020101

Title: Sulfur mustard-stimulated protease: a target for antivesicant drugs.

Journal: Journal of applied toxicology : JAT 20020101

Title: Treatment of cutaneous T cell lymphoma: current status and future directions.

Journal: American journal of clinical dermatology 20020101

Title: ABVD versus stanford V versus MEC in unfavourable Hodgkin's lymphoma: results of a randomised trial.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020101

Title: From poison gas to wonder drug.

Journal: American heritage of invention & technology 20020101

Title: [Cured from Hodgkin's disease].

Journal: Bulletin du cancer 20020101

Title: MOPP chemotherapy for treatment of resistant lymphoma in dogs: a retrospective study of 117 cases (1989-2000).

Journal: Journal of veterinary internal medicine 20020101

Title: Radiotherapy alone for lymphocyte-predominant Hodgkin's disease.

Journal: Cancer journal (Sudbury, Mass.) 20020101

Title: [Z-form of intraphage DNA].

Journal: Molekuliarnaia genetika, mikrobiologiia i virusologiia 20020101

Title: Nitrogen mustard hydrochloride.

Journal: Report on carcinogens : carcinogen profiles 20020101

Title: Chromatin structure at the 3'-boundary of the human beta-globin locus control region hypersensitive site-2.

Journal: The international journal of biochemistry & cell biology 20011201

Title: The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange.

Journal: Carcinogenesis 20011201

Title: Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.

Journal: Clinical lymphoma 20011201

Title: Adult lymphoblastic lymphoma in Taiwan: an analysis of treatment results of 26 patients.

Journal: Annals of hematology 20011101

Title: ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of Hodgkin's disease.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010901

Title: Advanced Hodgkin disease with large mediastinal involvement can be treated with eight cycles of chemotherapy alone after a major response to six cycles of chemotherapy: a study of 82 patients from the Groupes d'Etudes des Lymphomes de l'Adulte H89 trial.

Journal: Cancer 20010801

Title: Induction of apoptosis by estramustine phosphate mediated by phosphorylation of bcl-2.

Journal: Journal of neuro-oncology 20010801

Title: Follicular mycosis fungoides: a case report and review of the literature.

Journal: Journal of cutaneous pathology 20010701

Title: Genetic damage by bifunctional agents in repair-active pre-meiotic stages of Drosophila males.

Journal: Mutation research 20010701

Title: The serum levels of eosinophil cationic protein (ECP) are related to the infiltration of eosinophils in the tumours of patients with Hodgkin's disease.

Journal: Leukemia & lymphoma 20010701

Title: Prophylactic efficacy of amifostine and its analogues against sulphur mustard toxicity.

Journal: Toxicology 20010621

Title: Chlorophyllin protects cells from the cytostatic and cytotoxic effects of quinacrine mustard but not of nitrogen mustard.

Journal: International journal of oncology 20010401

Title: The risk of second malignant tumors and its consequences for the overall survival of Hodgkin's disease patients and for the choice of their treatment at presentation: analysis of a series of 1524 cases consecutively treated at the Florence University Hospital.

Journal: International journal of radiation oncology, biology, physics 20010401

Title: [The chemotherapeutic treatment of advanced Hodgkin's disease].

Journal: Harefuah 20010401

Title: Lung cancer after Hodgkin's disease: a nested case-control study of the relation to treatment.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010315

Title: Inhibition by leukocyte depletion of neointima formation after balloon angioplasty in a rabbit model of restenosis.

Journal: Cardiovascular research 20010301

Title: Chlorambucil drug resistance in chronic lymphocytic leukemia: the emerging role of DNA repair.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010301

Title: DNA interstrand crosslink formation by mechlorethamine at a cytosine-cytosine mismatch pair: kinetics and sequence dependence.

Journal: Archives of biochemistry and biophysics 20010215

Title: The influence of mechlorethamine on the activity of ecto-ATPase of rat lymphocytes.

Journal: Annales pharmaceutiques francaises 20010201

Title: Hypopigmented mycosis fungoides: a report of 7 cases and review of the literature.

Journal: Cutis 20010201

Title: Current treatment of Cutaneous T-Cell Lymphoma.

Journal: Dermatology online journal 20010201

Title: Persistent paraneoplastic neurologic syndrome after successful therapy of Hodgkin's disease.

Journal: European journal of haematology 20010101

Title: Hodgkin's disease: clinical presentation and treatment.

Journal: Cancer treatment and research 20010101

Title: Gingival overgrowth as the initial paraneoplastic manifestation of Hodgkin's lymphoma in a child. A case report.

Journal: Journal of periodontology 20010101

Title: Treatment of advanced stage Hodgkin's disease.

Journal: Oncology 20010101

Title: Treatment of VX2 carcinoma implanted in the liver with arterial and intraperitoneal administration of oily anticancer agents.

Journal: Cancer chemotherapy and pharmacology 20010101

Title: [Gene protective effect of the short-chain derivative of Vitamin E under the action of alkylating compounds].

Journal: TSitologiia i genetika 20010101

Title: [Successful chemotherapy of cancer. Remission of Hodgkin's disease. IV].

Journal: La Clinica terapeutica 20010101

Title: Coexpression of rat glutathione S-transferase A3 and human cytidine deaminase by a bicistronic retroviral vector confers in vitro resistance to nitrogen mustards and cytosine arabinoside in murine fibroblasts.

Journal: Cancer gene therapy 20000501

Title: Early nonsurgical removal of chemically injured tissue enhances wound healing in partial thickness burns.

Journal: Burns : journal of the International Society for Burn Injuries 19980301

Title: Histopathologic and immunohistochemical features in human skin after exposure to nitrogen and sulfur mustard.

Journal: The American Journal of dermatopathology 19980201

Title: Aortic dissection in a patient receiving chemotherapy for Hodgkin's disease--a case report.

Journal: Angiology 19971201

Title: N-acetylcysteine protects lymphocytes from nitrogen mustard-induced apoptosis.

Journal: Biochemical pharmacology 19960503

Title: Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers in vitro resistance to alkylating agents in human leukemia cells and in clonogenic mouse hematopoietic progenitor cells.

Journal: Human gene therapy 19960501

Title: Effect of some anticancer drugs and combined chemotherapy on renal toxicity.

Journal: Biological signals 19960101

Title: Genetic instability in patients with Hodgkin's disease undergoing chemotherapy.

Journal: The Journal of clinical investigation 19951201

Title: Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers alkylating drug resistance in NIH 3T3 mouse fibroblasts.

Journal: Cancer research 19940815

Title: Decrease in penbutolol protein binding as a consequence of treatment with some alkylating agents.

Journal: Cancer chemotherapy and pharmacology 19940101

Title: Late cardiac toxicity of doxorubicin, epirubicin, and mitoxantrone therapy for Hodgkin's disease in adults.

Journal: Leukemia & lymphoma 19931001

Title: Granulocyte colony stimulating factor (G-CSF) for mustard-induced bone marrow suppression.

Journal: Military medicine 19930701

Title: G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.

Journal: The Journal of biological chemistry 19930415

Title: Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies.

Journal: Blood reviews 19920901

Title: [Recurrent paralysis induced by vincristine during the treatment of Hodgkin's disease].

Journal: Presse medicale (Paris, France : 1983) 19891125

Title: [Secondary leukemia (AML) with TcR beta rearrangement].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 19890801

Title: Reversible mechlorethamine-associated hearing loss in a patient with Hodgkin's disease.

Journal: Cancer 19860315

Title: MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19850901

Title: BCVPP chemotherapy for advanced Hodgkin's disease: evidence for greater duration of complete remission, greater survival, and less toxicity than with a MOPP regimen. Results of the Eastern Cooperative Oncology Group study.

Journal: Annals of internal medicine 19841001

Title: Combination chemotherapy for advanced Hodgkin's disease after failure of MOPP: ABVD and B-CAVe.

Journal: Annals of internal medicine 19841001

Title: Immediate and delayed neurotoxicity after mechlorethamine preparation for bone marrow transplantation.

Journal: Annals of internal medicine 19820801

Title: Central nervous system disturbances after combined administration of procarbazine and mechlorethamine.

Journal: Cancer treatment reports 19771201

Title: Failure to induce tolerance to mechlorethamine hydrochloride.

Journal: Archives of dermatology 19771001

Title: [Increased hematological toxicity of antineoplastic drugs with simultaneous androgenotherapy (author's transl)].

Journal: La Nouvelle presse medicale 19770917

Title: Combination chemotherapy-radiotherapy for stage 3 Hodgkin's disease. An acute leukemia group B study.

Journal: Archives of internal medicine 19730301

Title: Combination chemotherapy of Hodgkin's disease in private practice.

Journal: JAMA 19720717

Title: Severe cerebral toxicity after intravenous nitrogen mustard therapy.

Journal: Cancer 19720201

Title: Hemorrhagic encephalopathy induced by cyclophosphamide (NSC-26271) in suckling rats.

Journal: Cancer chemotherapy reports 19700801

Title: Successful therapy of trimethadione nephrosis with prednisone and cyclophosphamide. Report of a case.

Journal: The Journal of pediatrics 19670801

Title: Cao Z, et al. Effect of brentuximab vedotin combined with chlormethine hydrochloride on the treatment of 6 patients with relapsed and refractory Hodgkin lymphoma. Zhonghua Xue Ye Xue Za Zhi. 2015 Jul 14;36(7):575-577.

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Tags:55-86-7 Molecular Formula|55-86-7 MDL|55-86-7 SMILES|55-86-7 Bis(2-chloroethyl)-N-methylamine hydrochloride |Organic_Building_Blocks