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601-75-2,MFCD00002668
Catalog No.:AA003382

601-75-2 | Ethylmalonic acid

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1g
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in stock  
$6.00   $4.00
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5g
97%
in stock  
$12.00   $8.00
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10g
97%
in stock  
$21.00   $15.00
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25g
97%
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$50.00   $35.00
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100g
95%
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$143.00   $100.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003382
Chemical Name:
Ethylmalonic acid
CAS Number:
601-75-2
Molecular Formula:
C5H8O4
Molecular Weight:
132.1146
MDL Number:
MFCD00002668
SMILES:
CCC(C(=O)O)C(=O)O
NSC Number:
96615
Properties
Properties
 
BP:
199 °C  
Form:
Solid  
MP:
112-114 °C(lit.)  
Refractive Index:
1.4016 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
115  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
0.4  

Upstream Synthesis Route

[1]JournaloftheChemicalSociety,1948,p.631

[2]CanadianJournalofChemistry,1986,vol.64,p.1714-1720

[1]Patent:US6780887,2004,B1,

[1]OrganicPreparationsandProceduresInternational,2005,vol.37,#2,p.184-188

[2]BioorganicandMedicinalChemistry,2003,vol.11,#22,p.4685-4691

[3]RecueildesTravauxChimiquesdesPays-Bas,1897,vol.16,p.357

[4]DiePraxisdesorganischenChemikers,12.Aufl.<Leipzig1914>,S.177,

[5]JournalfuerPraktischeChemie(Leipzig),1905,vol.<2>72,p.554

[6]ChemischeBerichte,1905,vol.38,p.2096

[7]Chemistry-AEuropeanJournal,2011,vol.17,#30,p.8363-8370

[8]JournaloftheAmericanChemicalSociety,2015,vol.137,#51,p.15992-15995

[9]OrganicLetters,2016,vol.18,#3,p.348-351

[1]JustusLiebigsAnnalenderChemie,1876,vol.182,p.328

[2]ChemischeBerichte,1869,vol.2,p.720

[3]JustusLiebigsAnnalenderChemie,1873,vol.165,p.95

[4]JustusLiebigsAnnalenderChemie,1874,vol.171,p.243

[5]JustusLiebigsAnnalenderChemie,1876,vol.182,p.328

[6]ChemischeBerichte,1869,vol.2,p.720

[7]JustusLiebigsAnnalenderChemie,1873,vol.165,p.95

[8]JustusLiebigsAnnalenderChemie,1874,vol.171,p.243

[1]JournaloftheChemicalSociety,1923,vol.123,p.1623

Downstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1958,vol.80,p.4949,4952

[1]JournaloftheAmericanChemicalSociety,1958,vol.80,p.4949,4952

[1]JournaloftheAmericanChemicalSociety,1958,vol.80,p.4949,4952

[1]ChemischeBerichte,1905,vol.38,p.2733

90-46-0    601-75-2   
2-xanthen-9-yl-butyricacid 

[1]JournaloftheChemicalSociety,1956,p.812

Literature

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Title: Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.

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Journal: PloS one 20100101

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Journal: Nature medicine 20090201

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Journal: Molecular genetics and metabolism 20081201

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Journal: Acta crystallographica. Section E, Structure reports online 20080801

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Journal: Nederlands tijdschrift voor geneeskunde 20080726

Title: Severe infantile hypotonia with ethylmalonic aciduria: case report.

Journal: Journal of child neurology 20080601

Title: Acquired multiple Acyl-CoA dehydrogenase deficiency in 10 horses with atypical myopathy.

Journal: Neuromuscular disorders : NMD 20080501

Title: (E)-2-(2-Fluoro-benzyl-idene)butanoic acid.

Journal: Acta crystallographica. Section E, Structure reports online 20080401

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Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20071201

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Journal: Molecular genetics and metabolism 20070801

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Journal: Neuropediatrics 20070401

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Journal: Journal of medical genetics 20060401

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Journal: Clinical biochemistry 20060301

Title: Inhibition of the electron transport chain and creatine kinase activity by ethylmalonic acid in human skeletal muscle.

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SDS
Tags:601-75-2 Molecular Formula|601-75-2 MDL|601-75-2 SMILES|601-75-2 Ethylmalonic acid