Home Nitro Compounds 609-40-5
609-40-5,MFCD00005425
Catalog No.:AA0033C9

609-40-5 | 2-Nitrothiophene

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
85%
in stock  
$7.00   $5.00
- +
5g
85%
in stock  
$19.00   $14.00
- +
25g
85%
in stock  
$94.00   $66.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0033C9
Chemical Name:
2-Nitrothiophene
CAS Number:
609-40-5
Molecular Formula:
C4H3NO2S
Molecular Weight:
129.1371
MDL Number:
MFCD00005425
SMILES:
[O-][N+](=O)c1cccs1
NSC Number:
5371
Properties
Properties
 
BP:
224.5°C at 760 mmHg  
Form:
Solid  
MP:
43-45 °C(lit.);  
Refractive Index:
1.5740 (estimate)  
Stability:
Light Sensitive  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
101  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
XLogP3:
1.6  

Literature

Title: (Z)-2-Meth-oxy-N-[(5-nitro-thio-phen-2-yl)methyl-idene]aniline.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: 2-Ethyl-N-[(5-nitro-thio-phen-2-yl)methyl-idene]aniline.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: Synthesis and antileishmanial activity of 5-(5-nitroaryl)-2-substituted-thio-1,3,4-thiadiazoles.

Journal: Journal of enzyme inhibition and medicinal chemistry 20110201

Title: 2,3-Dibromo-1-(4-methyl-phen-yl)-3-(5-nitro-furan-2-yl)propan-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Helicobacter pylori Induces Disturbances in Gastric Mucosal Akt Activation through Inducible Nitric Oxide Synthase-Dependent S-Nitrosylation: Effect of Ghrelin.

Journal: ISRN gastroenterology 20110101

Title: 2-[(2Z,3E)-2-Hy-droxy-imino-5-phenyl-2,3-dihydro-3-thienyl-idene]-2-phenyl-acetonitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: [3-(5-Nitro-2-fur-yl)-1-phenyl-1H-pyrazol-4-yl](phen-yl)methanone.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: New dioxazole derivatives: Synthesis and effects on the growth of Entamoeba histolytica and Giardia intestinalis.

Journal: European journal of medicinal chemistry 20100401

Title: Aryl azides formation under mild conditions: a kinetic study in some ionic liquid solutions.

Journal: The Journal of organic chemistry 20100205

Title: Ghrelin protection against lipopolysaccharide-induced gastric mucosal cell apoptosis involves constitutive nitric oxide synthase-mediated caspase-3 S-nitrosylation.

Journal: Mediators of inflammation 20100101

Title: Mechanism of Cytosolic Phospholipase A(2) Activation in Ghrelin Protection of Salivary Gland Acinar Cells against Ethanol Cytotoxicity.

Journal: Advances in pharmacological sciences 20100101

Title: Suppression by Ghrelin of Porphyromonas gingivalis-Induced Constitutive Nitric Oxide Synthase S-Nitrosylation and Apoptosis in Salivary Gland Acinar Cells.

Journal: Journal of signal transduction 20100101

Title: (4-Methyl-phen-yl)[1-(4-methyl-phen-yl)-3-(5-nitro-2-fur-yl)-1H-pyrazol-4-yl]methanone.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Selective leishmanicidal effect of 1,3,4-thiadiazole derivatives and possible mechanism of action against Leishmania species.

Journal: Experimental parasitology 20090401

Title: Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.

Journal: European journal of medicinal chemistry 20080901

Title: Convenient access to 1,3,4-trisubstituted pyrazoles carrying 5-nitrothiophene moiety via 1,3-dipolar cycloaddition of sydnones with acetylenic ketones and their antimicrobial evaluation.

Journal: European journal of medicinal chemistry 20080801

Title: Antileishmanial activity screening of 5-nitro-2-heterocyclic benzylidene hydrazides.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Synthesis and anti-Helicobacter pylori activity of 5-(nitroaryl)-1,3,4-thiadiazoles with certain sulfur containing alkyl side chain.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl]- and 1-[5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines.

Journal: Bioorganic & medicinal chemistry 20080415

Title: Reactions of nitroheteroarenes with carbanions: bridging aromatic, heteroaromatic, and vinylic electrophilicity.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Butadienic building blocks from 2-nitrothiophene as precursors of nitrogen heterocycles: intriguing dichotomic behavior.

Journal: The Journal of organic chemistry 20071123

Title: Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines.

Journal: Bioorganic & medicinal chemistry letters 20071001

Title: Oxidative nucleophilic substitution of hydrogen versus ring-opening in the reaction of 4-R-2-nitrothiophenes with amines. The crucial effect of 4-alkyl groups.

Journal: The Journal of organic chemistry 20070720

Title: A new class of nifuroxazide analogues: synthesis of 5-nitrothiophene derivatives with antimicrobial activity against multidrug-resistant Staphylococcus aureus.

Journal: Bioorganic & medicinal chemistry 20070615

Title: Synthesis of alpha,beta-unsaturated ketones as chalcone analogues via a S(RN)1 mechanism.

Journal: Molecules (Basel, Switzerland) 20070418

Title: Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.

Journal: Drug target insights 20070101

Title: Structure-activity relationships in nitrothiophenes.

Journal: Bioorganic & medicinal chemistry 20061201

Title: Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4.

Journal: Molecular cancer therapeutics 20061101

Title: Studies on the biological activity of some nitrothiophenes.

Journal: Organic & biomolecular chemistry 20060121

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles.

Journal: Journal of medicinal chemistry 20040617

Title: Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead.

Journal: Journal of medicinal chemistry 20030130

Title: Pathways of reductive fragmentation of heterocyclic nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine.

Journal: Radiation research 20021201

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 609-40-5
Tags:609-40-5 Molecular Formula|609-40-5 MDL|609-40-5 SMILES|609-40-5 2-Nitrothiophene |Heterocyclic_Building_Blocks |Organic_Building_Blocks