Home Aldehydes 139-85-5
139-85-5,MFCD00003370
Catalog No.:AA0033FU

139-85-5 | 3,4-Dihydroxybenzaldehyde

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1g
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$6.00   $4.00
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5g
98%
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$7.00   $5.00
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10g
98%
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$8.00   $5.00
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25g
98%
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$9.00   $6.00
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100g
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500g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0033FU
Chemical Name:
3,4-Dihydroxybenzaldehyde
CAS Number:
139-85-5
Molecular Formula:
C7H6O3
Molecular Weight:
138.1207
MDL Number:
MFCD00003370
SMILES:
O=Cc1ccc(c(c1)O)O
NSC Number:
22961
Properties
Properties
 
BP:
213.5°C (rough estimate)  
Form:
Solid  
MP:
150-157 °C  
Refractive Index:
1.4600 (estimate)  
Solubility:
6.3g/l  
Stability:
Air Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
124  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.3  

Upstream Synthesis Route

[1]Patent:US2011/87027,2011,A1,

[2]Patent:WO2012/49555,2012,A1,

[3]EuropeanJournalofMedicinalChemistry,2018,vol.157,p.380-396

[1]JournalofMedicinalChemistry,2007,vol.50,#17,p.4122-4134

[2]Patent:WO2005/105753,2005,A2,.Locationinpatent:Page/Pagecolumn63-64

[3]TetrahedronLetters,1988,vol.29,#22,p.2665-2666

[4]BioorganicandMedicinalChemistry,2000,vol.8,#1,p.251-268

[5]RSCAdvances,2015,vol.5,#91,p.74425-74437

[6]EuropeanJournalofMedicinalChemistry,2018,vol.157,p.380-396

[7]Patent:CN108117534,2018,A,.Locationinpatent:Paragraph0844;0845;0846

[8]Patent:US2011/87027,2011,A1,.Locationinpatent:Page/Pagecolumn11

[9]BioorganicandMedicinalChemistryLetters,2011,vol.21,#24,p.7251-7254

[10]MonatsheftefurChemie,2018,vol.149,#12,p.2265-2285

[11]SyntheticCommunications,2001,vol.31,#1,p.1-7

[12]Farmaco,EdizioneScientifica,1983,vol.38,#4,p.265-273

[13]YakugakuZasshi,1957,vol.77,p.478,479

[14]Chem.Zentralbl.,1957,vol.128,p.14728

[15]JournaloftheChemicalSociety,1937,p.49,52

[16]Patent:WO2010/75469,2010,A1,.Locationinpatent:Page/Pagecolumn123

[17]Patent:US2011/9628,2011,A1,.Locationinpatent:Page/Pagecolumn43

[18]Patent:WO2012/49555,2012,A1,.Locationinpatent:Page/Pagecolumn56

[19]BioorganicandMedicinalChemistryLetters,2012,vol.22,#18,p.5870-5875

[20]BioorganicandMedicinalChemistry,2013,vol.21,#2,p.448-455

[21]BioorganicandMedicinalChemistryLetters,2013,vol.23,#4,p.1091-1095

[22]RSCAdvances,2014,vol.4,#45,p.23904-23913

[23]BioorganicandMedicinalChemistry,2016,vol.24,#21,p.5626-5632

[24]Patent:CN105801556,2016,A,.Locationinpatent:Paragraph0006;0011;0012

[25]Fitoterapia,2018,vol.129,p.25-33

[1]JournalofAgriculturalandFoodChemistry,2018,

[2]BioorganicandMedicinalChemistryLetters,2018,vol.28,#23-24,p.3634-3638

[1]OrganicandBiomolecularChemistry,2011,vol.9,#3,p.902-905

[1]ArchivderPharmazie(Weinheim,Germany),1928,p.119

Downstream Synthesis Route

[1]BioorganicandMedicinalChemistryLetters,2011,vol.21,p.4520-4523

[2]JustusLiebigsAnnalenderChemie,1914,vol.405,p.268

[3]JournaloftheChemicalSociety,1955,p.1589,1592

60032-63-5   
furan-2,3,5(4H)-trionepyridine(1:1) 
  139-85-5 

[1]Patent:DE82078,    Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.4,p.134

[1]JournalofPhysicalOrganicChemistry,2012,vol.25,p.1261-1268

[2]TetrahedronLetters,1999,vol.40,p.7031-7033

[3]JournalofMedicinalChemistry,1989,vol.32,p.2344-2352

[4]JournalofPharmaceuticalSciences,1991,vol.80,p.416-418

[5]JustusLiebigsAnnalenderChemie,1924,vol.437,p.143

[6]JournalofMedicinalChemistry,1991,vol.34,p.1503-1505

[7]JournalofMedicinalChemistry,2000,vol.43,p.1550-1562

[8]JournalofHeterocyclicChemistry,2018,vol.55,p.181-186

[1]DissertationesPharmaceuticaeetPharmacologicae,1966,vol.18,p.51    Chem.Abstr.,1966,vol.65,p.3786

[2]ChimicaTherapeutica,1969,vol.4,p.120-126

[1]JournaloftheAmericanChemicalSociety,1955,vol.77,p.1196,1197

Literature

Title: 3,4-Dihydroxybenzaldehyde quenches ROS and RNS and protects human blood cells from Cr(VI)-induced cytotoxicity and genotoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180801

Title: 3,4-Dihydroxybenzaldehyde lowers ROS generation and protects human red blood cells from arsenic(III) induced oxidative damage.

Journal: Environmental toxicology 20180506

Title: Protocatechuic aldehyde ameliorates experimental pulmonary fibrosis by modulating HMGB1/RAGE pathway.

Journal: Toxicology and applied pharmacology 20150215

Title: Anticancer activity of protocatechualdehyde in human breast cancer cells.

Journal: Journal of medicinal food 20140801

Title: Protocatechualdehyde possesses anti-cancer activity through downregulating cyclin D1 and HDAC2 in human colorectal cancer cells.

Journal: Biochemical and biophysical research communications 20130104

Title: Three-channel column-switching high-performance liquid chromatography with electrochemical detection for determining bioactive redox components in Salvia miltiorrhiza.

Journal: Journal of chromatography. A 20120921

Title: Effects of ortho substituent groups of protocatechualdehyde derivatives on binding to the C1 domain of novel protein kinase C.

Journal: The journal of physical chemistry. B 20120906

Title: Protocatechuic aldehyde inhibits lipopolysaccharide-induced human umbilical vein endothelial cell apoptosis via regulation of caspase-3.

Journal: Phytotherapy research : PTR 20120901

Title: Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation.

Journal: Analytica chimica acta 20120706

Title: [Chemical constituents contained in Salvia castanea].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120701

Title: Protocatechuic aldehyde inhibits migration and proliferation of vascular smooth muscle cells and intravascular thrombosis.

Journal: Biochemical and biophysical research communications 20120622

Title: A novel on-line gold nanoparticle-catalyzed luminol chemiluminescence detector for high-performance liquid chromatography.

Journal: Journal of chromatography. A 20120615

Title: Metabolite profiling and pharmacokinetics of herbal compounds following oral administration of a cardiovascular multi-herb medicine (Qishen yiqi pills) in rats.

Journal: Current drug metabolism 20120601

Title: Synthesis, characterization and biological evaluation of Fe (III), Co (II), Ni(II), Cu(II), and Zn(II) complexes with tetradentate Schiff base ligand derived from protocatechualdehyde with 2-aminophenol.

Journal: Applied biochemistry and biotechnology 20120601

Title: Protocatechuic aldehyde protects against experimental sepsis in vitro and in vivo.

Journal: Basic & clinical pharmacology & toxicology 20120401

Title: Antifibrotic effects of protocatechuic aldehyde on experimental liver fibrosis.

Journal: Pharmaceutical biology 20120401

Title: [Sesquiterpenoids of Coniogramme maxima].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

Title: [Study on the chemical constituents from Cyathea spinulosa].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120401

Title: Qualitative and quantitative analysis of the major constituents in Chinese medicinal preparation Guan-Xin-Ning injection by HPLC-DAD-ESI-MS(n).

Journal: Journal of pharmaceutical and biomedical analysis 20120205

Title: Antirheumatoid Arthritis Activities and Chemical Compositions of Phenolic Compounds-Rich Fraction from Urtica atrichocaulis, an Endemic Plant to China.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: A new inositol derivative from Prenanthes macrophylla.

Journal: Journal of Asian natural products research 20120101

Title: Current approaches toward production of secondary plant metabolites.

Journal: Journal of pharmacy & bioallied sciences 20120101

Title: Optimal production of L-threo-2,3-dihydroxyphenylserine (L-threo-DOPS) on a large scale by diastereoselectivity-enhanced variant of L-threonine aldolase expressed in Escherichia coli.

Journal: Preparative biochemistry & biotechnology 20120101

Title: Tanshinone IIA: A Promising Natural Cardioprotective Agent.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Simultaneous quantitative determination of 9 active components in traditional Chinese medicinal preparation ShuangDan oral liquid by RP-HPLC coupled with photodiode array detection.

Journal: Journal of pharmaceutical and biomedical analysis 20111205

Title: Protocatechualdehyde synergizes with aspirin at the platelet cyclooxygenase-1 level.

Journal: Planta medica 20111101

Title: Ethnobotanical survey, chemical composition, and antioxidant capacity of methanolic extract of the root bark of Annona cuneata Oliv.

Journal: Journal of medicinal food 20111101

Title: [Network pharmacology study on major active compounds of Fufang Danshen formula].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101

Title: 4-[Bis(3-phenyl-1H-pyrazol-1-yl)meth-yl]benzene-1,2-diol.

Journal: Acta crystallographica. Section E, Structure reports online 20111001

Title: Development of fluorescence imaging-based assay for screening cardioprotective compounds from medicinal plants.

Journal: Analytica chimica acta 20110919

Title: Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon thyme, mint, oregano, rosemary, sage, and thyme.

Journal: International journal of food sciences and nutrition 20110901

Title: [A quantitative method for simultaneous assay of five ingredients with one marker in Salvia miltiorrhiza].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901

Title: Functional characterization of two new members of the caffeoyl CoA O-methyltransferase-like gene family from Vanilla planifolia reveals a new class of plastid-localized O-methyltransferases.

Journal: Plant molecular biology 20110801

Title: Pharmacokinetics of phenolic compounds of Danshen extract in rat blood and brain by microdialysis sampling.

Journal: Journal of ethnopharmacology 20110614

Title: [Capillary electrophoresis with field-enhanced stacking for determination of water-soluble active principles in Salvia miltiorrhiza var. miltiorrhiza f. alba].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601

Title: Effect of toasting intensity at cooperage on phenolic compounds in acacia (Robinia pseudoacacia) heartwood.

Journal: Journal of agricultural and food chemistry 20110413

Title: Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110401

Title: [Pharmacokinetics of three phenolic acids of xiangdan injection in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401

Title: Dialysis sampling on-line coupled with high-performance liquid chromatography for simultaneous investigation of the interactions between multi-components in herbs and the albumin.

Journal: The Analyst 20110221

Title: Radical-scavenging properties of ferrocenyl chalcones.

Journal: Bioorganic & medicinal chemistry letters 20110201

Title: A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality control of guan-xin-er-hao formula.

Journal: Journal of ethnopharmacology 20110127

Title: A chinese herbal preparation containing radix salviae miltiorrhizae, radix notoginseng and borneolum syntheticum reduces circulating adhesion molecules.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: DJ-1-Mediated protective effect of protocatechuic aldehyde against oxidative stress in SH-SY5Y cells.

Journal: Journal of pharmacological sciences 20110101

Title: Myocardial post-conditioning with Danshen-Gegen decoction protects against isoproterenol-induced myocardial injury via a PKCε/mKATP-mediated pathway in rats.

Journal: Chinese medicine 20110101

Title: [Effects of Salvia miltiorrhiza and Carthamus tinctorius aqueous extracts and compatibility on rat myocardial ischemic reperfusion injury].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110101

Title: In vitro antioxidant and anti-inflammatory activities of protocatechualdehyde isolated from Phellinus gilvus.

Journal: Journal of nutritional science and vitaminology 20110101

Title: Antioxidant hispidin derivatives from medicinal mushroom Inonotus hispidus.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Simultaneous determination of six phenolic constituents of Danshen injection in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study.

Journal: European journal of mass spectrometry (Chichester, England) 20110101

Title: Studies on synthesis and structure-activity relationship (SAR) of derivatives of a new natural product from marine fungi as inhibitors of influenza virus neuraminidase.

Journal: Marine drugs 20110101

Title: Inhibition of protein tyrosine phosphatase 1beta by hispidin derivatives isolated from the fruiting body of Phellinus linteus.

Journal: Natural product communications 20101201

Title: Effect of varying feedstock-pretreatment chemistry combinations on the formation and accumulation of potentially inhibitory degradation products in biomass hydrolysates.

Journal: Biotechnology and bioengineering 20101015

Title: [Active compounds from rhizomes of Musa basjoo].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

Title: [Study on the chemical constituents of Antipathes dichotoma].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100901

Title: Para-quinone-containing bis(pyrazol-1-yl)methane ligands: coordination behavior toward Co(II) and a C-H activation reaction with Ce(IV).

Journal: Inorganic chemistry 20100816

Title: The battle for iron between bacterial pathogens and their vertebrate hosts.

Journal: PLoS pathogens 20100801

Title: The theoretical and experimental study on dicalcium phosphate dehydrate loading with protocatechuic aldehyde.

Journal: Journal of molecular modeling 20100701

Title: [Determination of tanshinol and protocatechuic aldehyde in shenkangling granula by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701

Title: Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats.

Journal: Acta pharmacologica Sinica 20100501

Title: 3,3,4,4-Tetra-fluoro-2,3,4,5-tetra-hydro-1,6-benzodioxocine-8-carbaldehyde.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: [Studies on the chemical constituents of marine sponge Iotrochota sp].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100401

Title: Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.

Journal: Bioorganic & medicinal chemistry 20100315

Title: Synthesis and biological evaluation of caffeic acid 3,4-dihydroxyphenethyl ester.

Journal: Journal of natural products 20100226

Title: Phenolic substance characterization and chemical and cell-based antioxidant activities of 11 lentils grown in the northern United States.

Journal: Journal of agricultural and food chemistry 20100210

Title: Bioactive phenols in algae: the application of pressurized-liquid and solid-phase extraction techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20100120

Title: Catechol derivatives-coated Fe3O4 and gamma-Fe2O3 nanoparticles as potential MRI contrast agents.

Journal: Journal of colloid and interface science 20100115

Title: Antioxidant activity in barley (Hordeum Vulgare L.) grains roasted in a microwave oven under conditions optimized using response surface methodology.

Journal: Journal of food science 20100101

Title: Improved vanillin production in baker's yeast through in silico design.

Journal: Microbial cell factories 20100101

Title: Antioxidant activity of a red lentil extract and its fractions.

Journal: International journal of molecular sciences 20091201

Title: Anti-tumor-initiating effects of phenolic compounds isolated from the bark of Picea jezoensis var. jezoensis.

Journal: Bioorganic & medicinal chemistry 20090901

Title: Chemical characteristics of Salvia miltiorrhiza (Danshen) collected from different locations in China.

Journal: Journal of agricultural and food chemistry 20090812

Title: [Affects of different bioreactors in process of Salvia miltiorrhiza adventitious root culture].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090801

Title: [Dynamic changes of content of salvianolic acid in vegetative organs of Salvia miltiorrhiza].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090801

Title: [Establishment of reporter gene-based cell screening model for discovering new chemopreventive agents].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090701

Title: [Capillary electrophoresis fingerprints of compound Danshen Dropping Pill].

Journal: Se pu = Chinese journal of chromatography 20090701

Title: An updated review of tyrosinase inhibitors.

Journal: International journal of molecular sciences 20090601

Title: [Study on preparation and release mechanism of effervescent osmotic pump tablet of compound Danshen].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

Title: [Isolation and characterization of polyphenols in seed of Litchi chinensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090401

Title: Enhanced synthesis of L-threo-3,4-dihydroxyphenylserine by high-density whole-cell biocatalyst of recombinant L-threonine aldolase from Streptomyces avelmitilis.

Journal: Biotechnology letters 20090301

Title: Separation and on-line preconcentration by stacking and sweeping of charged analytes in the plant by microemulsion electrokinetic chromatography with nonionic surfactants.

Journal: Journal of pharmaceutical and biomedical analysis 20090220

Title: Effect of Guanxin No.2 decoction on gene expression in different areas of the myocardial infarcted heart of rats using microarray technology.

Journal: The Journal of pharmacy and pharmacology 20090201

Title: Solid-phase/supercritical-fluid extraction for liquid chromatography of phenolic compounds in freshwater microalgae and selected cyanobacterial species.

Journal: Journal of chromatography. A 20090130

Title: Cardioprotection by Guanxin II in rats with acute myocardial infarction is related to its three compounds.

Journal: Journal of ethnopharmacology 20090121

Title: 3,4-dihydroxybenzaldehyde purified from the barley seeds (Hordeum vulgare) inhibits oxidative DNA damage and apoptosis via its antioxidant activity.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20090101

Title: [Preparation and release characterization in vitro of pulsed-release tablets of compound Danshen].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090101

Title: Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs.

Journal: Journal of hematology & oncology 20090101

Title: Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels.

Journal: Molecular vision 20090101

Title: Antitumor and antioxidant activity of protocatechualdehyde produced from Streptomyces lincolnensis M-20.

Journal: Archives of pharmacal research 20081201

Title: [Simultaneous determination of water-soluble components and nerolidol in xiangdan injection by high performance liquid chromatography with column switching].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201

Title: The missing link in petrobactin biosynthesis: asbF encodes a (-)-3-dehydroshikimate dehydratase.

Journal: Biochemistry 20081125

Title: (E)-3,4-Dihydroxy-benzaldehyde 4-methyl-thio-semicarbazone.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: Simulated digestion and antioxidant activity of red wine fractions separated by high speed countercurrent chromatography.

Journal: Journal of agricultural and food chemistry 20081008

Title: Protein glycation inhibitors from the fruiting body of Phellinus linteus.

Journal: Biological & pharmaceutical bulletin 20081001

Title: LC-MS determination and pharmacokinetic study of six phenolic components in rat plasma after taking traditional Chinese medicinal-preparation: Guanxinning lyophilized powder for injection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080915

Title: Determination of four polyphenolic active ingredients from a pharmaceutical preparation by capillary zone electrophoresis with amperometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20080910

Title: A highly sensitive spectrophotometric determination of micro amounts of vanadium(V) in environmental and alloy samples by using 3,4-dihydroxybenzaldehydeisonicotinoylhydrazone (3,4-DHBINH).

Journal: Environmental monitoring and assessment 20080901

Title: Simultaneous detection of seven phenolic acids in Danshen injection using HPLC with ultraviolet detector.

Journal: Journal of Zhejiang University. Science. B 20080901

Title: UDP-glucuronosyltransferase 1A6 is the major isozyme responsible for protocatechuic aldehyde glucuronidation in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Plasma and urinary tanshinol from Salvia miltiorrhiza (Danshen) can be used as pharmacokinetic markers for cardiotonic pills, a cardiovascular herbal medicine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: 3,4-Dihydroxy-benzaldehyde 4-phenyl-thio-semicarbazone.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: 3,4-Dihydroxy-benzaldehyde thio-semi-carbazone.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: Two new triterpenes from the Rhizome of Dryopteris crassirhizoma, and inhibitory activities of its constituents on human immunodeficiency virus-1 protease.

Journal: Chemical & pharmaceutical bulletin 20080501

Title: (E)-3,4-Dihydroxy-benzaldehyde 4-ethyl-thio-semicarbazone.

Journal: Acta crystallographica. Section E, Structure reports online 20080501

Title: Antimicrobial and antioxidative activities of bioactive constituents from Hydnophytum formicarum Jack.

Journal: Molecules (Basel, Switzerland) 20080418

Title: Inhibitory constituents of aldose reductase in the fruiting body of Phellinus linteus.

Journal: Biological & pharmaceutical bulletin 20080401

Title: Mechanistic study of electrochemical oxidation of 2,5-dihydroxybenzoic acid and 3,4-dihydroxybenzaldehyde in the presence of 3-hydroxy-1H-phenalene-1-one.

Journal: Chemical & pharmaceutical bulletin 20080401

Title: Dynamics of phenolic acids and lignin accumulation in metal-treated Matricaria chamomilla roots.

Journal: Plant cell reports 20080301

Title: [Development of full-quantified fingerprint for quality control of traditional Chinese medicines].

Journal: Se pu = Chinese journal of chromatography 20080301

Title: Determination of fifteen bioactive components in Radix et Rhizoma Salviae Miltiorrhizae by high-performance liquid chromatography with ultraviolet and mass spectrometric detection.

Journal: Biomedical chromatography : BMC 20080201

Title: Effect of phenolic aldehydes and flavonoids on growth and inactivation of Oenococcus oeni and Lactobacillus hilgardii.

Journal: Food microbiology 20080201

Title: Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion.

Journal: Pharmacology & therapeutics 20080201

Title: One-step purification of 3,4-dihydroxyphenyllactic acid, salvianolic acid B, and protocatechualdehyde from Salvia miltiorrhiza Bunge by isocratic stepwise hydrogen bond adsorption chromatography on cross-linked 12% agarose.

Journal: Journal of chromatographic science 20080201

Title: [Studies on the chemical constituents of Salvia miltiorrhiz of Lijiang].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080201

Title: Simultaneous determination of ten active components in traditional Chinese medicinal products containing both Gegen (Pueraria lobata) and Danshen (Salvia miltiorrhiza) by high-performance liquid chromatography.

Journal: Phytochemical analysis : PCA 20080101

Title: Apoptotic cell death through inhibition of protein kinase CKII activity by 3,4-dihydroxybenzaldehyde purified from Xanthium strumarium.

Journal: Natural product research 20080101

Title: Three novel compounds from the leaves of Smallanthus sonchifolius.

Journal: Journal of Asian natural products research 20080101

Title: [Protection of vascular endothelial cells from ox-LDL induced injury by protocatechualdehyde].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201

Title: Simultaneous determination and pharmacokinetic study of water-soluble and lipid-soluble components of danshen in rat plasma using HPLC-UV method.

Journal: Biomedical chromatography : BMC 20071101

Title: One single LC-MS/MS analysis for both phenolic components and tanshinones in Radix Salviae Miltiorrihizae and its medicinal products.

Journal: Talanta 20071015

Title: Oxidation chemistry of norepinephrine: partitioning of the O-quinone between competing cyclization and chain breakdown pathways and their roles in melanin formation.

Journal: Chemical research in toxicology 20071001

Title: Structures and radical-scavenging activities of phenolic constituents from the bark of Picea jezoensis var. jezoensis.

Journal: Journal of natural products 20071001

Title: Characterization of ligV essential for catabolism of vanillin by Sphingomonas paucimobilis SYK-6.

Journal: Bioscience, biotechnology, and biochemistry 20071001

Title: [Study on chemical constituents of Orobanche coerulescens].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071001

Title: [Inhibition effects of constituents of Radix Salviae Miltiorrhizae on proliferation and procollagen transcription of dermal fibroblasts in systemic sclerosis].

Journal: Zhonghua yi xue za zhi 20070911

Title: Improved quality evaluation of Radix Salvia miltiorrhiza through simultaneous quantification of seven major active components by high-performance liquid chromatography and principal component analysis.

Journal: Biomedical chromatography : BMC 20070901

Title: Liquid chromatography-tandem mass spectrometry analysis of protocatechuic aldehyde and its phase I and II metabolites in rat.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901

Title: [Studies on polyphenolic chemical constitutents from root of Salvia yunnansis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: [Separation of water-soluble active components in Salvia miltiorrhiza bge. f. alba using capillary zone electrophoresis].

Journal: Se pu = Chinese journal of chromatography 20070901

Title: Effect of protocatechualdehyde on receptor for advanced glycation end products and TGF-beta1 expression in human lens epithelial cells cultured under diabetic conditions and on lens opacity in streptozotocin-diabetic rats.

Journal: European journal of pharmacology 20070827

Title: Phytotoxic effects of 21 plant secondary metabolites on Arabidopsis thaliana germination and root growth.

Journal: Journal of chemical ecology 20070701

Title: Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha.

Journal: The Journal of pharmacy and pharmacology 20070701

Title: [Studies on HPLC-fingerprint of Rhizoma Fagopyri Dibotoryis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

Title: The effect of the major components of Salvia Miltiorrhiza Bunge on bone marrow cells.

Journal: Journal of ethnopharmacology 20070522

Title: Dehydrogenase based reagentless biosensor for monitoring phenylketonuria.

Journal: Biosensors & bioelectronics 20070515

Title: Synthesis of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) with thermostabilized low-specific L-threonine aldolase from Streptomyces coelicolor A3(2).

Journal: Journal of microbiology and biotechnology 20070501

Title: Protocatechuic aldehyde inhibits hepatitis B virus replication both in vitro and in vivo.

Journal: Antiviral research 20070401

Title: [Identification of jizhi syrup using HPLC fingerprint].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070401

Title: 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Journal: Bioorganic & medicinal chemistry 20070301

Title: Preparation and preliminary biological evaluation of a novel 109Pd labeled porphyrin derivative for possible use in targeted tumor therapy.

Journal: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20070301

Title: [Pharmacokinetic interactions between the main components in the extracts of Salvia miltiorrhiza Bge. in rat].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070301

Title: One-step separation and purification of 3,4-dihydroxyphenyllactic acid, salvianolic acid B and protocatechualdehyde from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20070126

Title: Hydrolytic kinetics of lithospermic acid B extracted from roots of Salvia miltiorrhiza.

Journal: Journal of pharmaceutical and biomedical analysis 20070117

Title: Simultaneous determination of seven active components of Fufang Danshen tablet by high performance liquid chromatography.

Journal: Biomedical chromatography : BMC 20070101

Title: Development and validation of an RP-HPLC method for quantitative determination of vanillin and related phenolic compounds in Vanilla planifolia.

Journal: Journal of separation science 20070101

Title: Isolation and characterization of two phenolic compounds from the stem bark of Musanga cecropioides R. Brown (Moraceae).

Journal: Acta poloniae pharmaceutica 20070101

Title: Free radical scavengers from the medicinal mushroom Inonotus xeranticus and their proposed biogenesis.

Journal: Bioorganic & medicinal chemistry letters 20061101

Title: [Qualitative fingerprint and quantitative determination of caffeic acid in compound dandelion enema].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20061001

Title: Siderophores of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis.

Journal: Biochemical and biophysical research communications 20060915

Title: [Studies on in vitro culture of adventitious root in Salvia miltiorrhiza].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060901

Title: [Determination of danshensu and protocatechuic aldehyde in Guanxinning injections by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20060901

Title: [Determination of danshensu and protocatechuic aldehyde in Guanxinning injection powder by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801

Title: Fibronectin is essential for hepatitis B virus propagation in vitro: may be a potential cellular target?

Journal: Biochemical and biophysical research communications 20060609

Title: Improved quality control method for Danshen products--consideration of both hydrophilic and lipophilic active components.

Journal: Journal of pharmaceutical and biomedical analysis 20060607

Title: Acid-promoted reaction of the stilbene antioxidant resveratrol with nitrite ions: mild phenolic oxidation at the 4'-hydroxystiryl sector triggering nitration, dimerization, and aldehyde-forming routes.

Journal: The Journal of organic chemistry 20060526

Title: Synthesis, physico-chemical and DNA interaction studies of homo- and hetero-trinuclear complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Comparison of protocatechuic aldchyde in Radix Salvia miltiorrhiza and corresponding pharmacological sera from normal and fibrotic rats by high performance liquid chromatography.

Journal: World journal of gastroenterology 20060414

Title: Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method.

Journal: Journal of pharmaceutical and biomedical analysis 20060411

Title: Determination of four water-soluble compounds in Salvia miltiorrhiza Bunge by high-performance liquid chromatography with a coulometric electrode array system.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060403

Title: [Study of chemical constituents in active parts of Mentha spicata III].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

Title: Polyphenolic constituents of Actaea racemosa.

Journal: Journal of natural products 20060301

Title: Evaluation of antiviral activity of compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus.

Journal: Planta medica 20051201

Title: [Analysis of four components in Fufang Danshen Tablets by high performance liquid chromatography with electrochemical and ultraviolet detections].

Journal: Se pu = Chinese journal of chromatography 20051101

Title: Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-alpha.

Journal: International immunopharmacology 20051001

Title: Synthesis of [13C]- and [14C]-labeled phenolic humus and lignin monomers.

Journal: Chemosphere 20050901

Title: Simultaneous determination of six phenolic constituents of danshen in human serum using liquid chromatography/tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050605

Title: Aldose reductase inhibitors from the fruiting bodies of Ganoderma applanatum.

Journal: Biological & pharmaceutical bulletin 20050601

Title: [Effects of mineral cations on the accumulation of tanshinone II A and protocatechuic aldehyde in the adventitious root culture of Salvia niltiorrhiza].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601

Title: Quantitative analysis of the marker compounds in Salvia miltiorrihiza root and its phytomedicinal preparations.

Journal: Chemical & pharmaceutical bulletin 20050501

Title: Protocatechuic aldehyde suppresses TNF-alpha-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells.

Journal: European journal of pharmacology 20050418

Title: Electrocatalytic oxidation of NADH at single-wall carbon-nanotube-paste electrodes: kinetic considerations for use of a redox mediator in solution and dissolved in the paste.

Journal: Analytical and bioanalytical chemistry 20050401

Title: On-line chemiluminescence determination protocatechuic aldehyde and protocatechuic acid in pharmaceutical preparations by capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20050401

Title: Biotransformation of benzaldehyde-type and acetophenone-type derivatives by Pharbitis nil hairy roots.

Journal: Chemical & pharmaceutical bulletin 20050401

Title: Simultaneous determination of five marker constituents in traditional Chinese medicinal preparation Le-Mai granule by high performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20050309

Title: Chemical fingerprint and metabolic fingerprint analysis of Danshen injection by HPLC-UV and HPLC-MS methods.

Journal: Journal of pharmaceutical and biomedical analysis 20050104

Title: Metabolic studies on the total phenolic acids from the roots of Salvia miltiorrhiza in rats.

Journal: Biomedical chromatography : BMC 20050101

Title: Enzymatic oxidation of vanillin, isovanillin and protocatechuic aldehyde with freshly prepared Guinea pig liver slices.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101

Title: [Studies on the chemical constituents in herb of Ranunculus sceleratus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101

Title: Chemiluminescence determination of pharmacologically active compounds by capillary electrophoresis.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: Synergistic effects of thiols and amines on antiradical efficiency of protocatechuic acid.

Journal: Journal of agricultural and food chemistry 20041229

Title: Purification, crystallization and preliminary X-ray crystallographic analysis of hydroxycinnamoyl-coenzyme A hydratase-lyase (HCHL), a crotonase homologue active in phenylpropanoid metabolism.

Journal: Acta crystallographica. Section D, Biological crystallography 20041201

Title: Anti-oxidative compounds in barley tea.

Journal: Bioscience, biotechnology, and biochemistry 20041201

Title: Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction.

Journal: Life sciences 20041112

Title: Simultaneous determination of chlorogenic acid, caffeic acid, ferulic acid, protocatechuic acid and protocatechuic aldehyde in Chinese herbal preparation by RP-HPLC.

Journal: Chemical & pharmaceutical bulletin 20041001

Title: Contribution of aldehyde oxidase, xanthine oxidase, and aldehyde dehydrogenase on the oxidation of aromatic aldehydes.

Journal: Chemical research in toxicology 20041001

Title: [Effect of danshensu, protocatechualdehyde and danshen injection on calcium ion concentration in cytoplasm of human erythrocytes].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20041001

Title: A comparison between the use of a redox mediator in solution and of surface modified electrodes in the electrocatalytic oxidation of nicotinamide adenine dinucleotide.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040901

Title: In-vitro cytotoxic activities of the major bromophenols of the red alga Polysiphonia lanosa and some novel synthetic isomers.

Journal: Journal of natural products 20040901

Title: [Study on adsorption of danshen water-soluble compounds with macroporous resin D301].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040901

Title: Characterization of a multifunctional methyltransferase from the orchid Vanilla planifolia.

Journal: Plant cell reports 20040701

Title: New non-nucleoside inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Journal: Biochemistry. Biokhimiia 20040701

Title: A sphingolipid and tyrosinase inhibitors from the fruiting body of Phellinus linteus.

Journal: Archives of pharmacal research 20040701

Title: Comparative study of electron mediators used in the electrochemical oxidation of NADH.

Journal: Biosensors & bioelectronics 20040515

Title: Phelligridins C-F: cytotoxic pyrano[4,3-c][2]benzopyran-1,6-dione and furo[3,2-c]pyran-4-one derivatives from the fungus Phellinus igniarius.

Journal: Journal of natural products 20040501

Title: O-Methylation of benzaldehyde derivatives by 'lignin specific' caffeic acid 3-O-methyltransferase.

Journal: Phytochemistry 20040401

Title: Inhibition of tyrosinase by protocatechuic aldehyde.

Journal: The American journal of Chinese medicine 20040101

Title: Characterization of acylated flavonoid-O-glycosides and methoxylated flavonoids from Tagetes maxima by liquid chromatography coupled to electrospray ionization tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Synthesis and antioxidant activity of 4-[2-(3,5-dimethoxyphenyl)ethenyl]-1,2-benzenediol, a metabolite of Sphaerophysa salsula.

Journal: Bioscience, biotechnology, and biochemistry 20031101

Title: Simultaneous determination and pharmacokinetic studies on (3,4-Dihydroxyphenyl)-lactic acid and protocatechuic aldehyde in rat serum after oral administration of Radix Salviae miltiorrhizae extract.

Journal: Journal of chromatographic science 20030701

Title: 6,7-dihydroxyisoquinoline-3-carboxylic acids are potent inhibitors on the binding of insulin-like growth factor (IGF) to IGF-binding proteins: optimization of the 1-position benzoyl side chain.

Journal: Bioorganic & medicinal chemistry letters 20030602

Title: [Determination of danshensu in rat serum after oral administer compound Salvia recipe].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030601

Title: Inhibition of tumor growth by S-3-1, a synthetic intermediate of salvianolic acid A.

Journal: Journal of Asian natural products research 20021201

Title: Growth stimulation of intestinal commensal Escherichia coli by catecholamines: a possible contributory factor in trauma-induced sepsis.

Journal: Shock (Augusta, Ga.) 20021101

Title: Isolation, cloning and expression of a multifunctional O-methyltransferase capable of forming 2,5-dimethyl-4-methoxy-3(2H)-furanone, one of the key aroma compounds in strawberry fruits.

Journal: The Plant journal : for cell and molecular biology 20020901

Title: [Medicinal resources of Salvia yunnanensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020901

Title: Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase.

Journal: European journal of biochemistry 20020801

Title: Aroma biosynthesis in strawberry: s-adenosylmethionine:furaneol o-methyltransferase activity in ripening fruits.

Journal: Journal of agricultural and food chemistry 20020703

Title: Peroxynitrite scavenging activities of aromatic compounds isolated from Konnyaku, Amorphophallus konjac K.Koch.

Journal: Bioscience, biotechnology, and biochemistry 20020601

Title: New insights into the acid-promoted reaction of caffeic acid and its esters with nitrite: decarboxylation drives chain nitrosation pathways toward novel oxime derivatives and oxidation/fragmentation products thereof.

Journal: The Journal of organic chemistry 20020208

Title: Development of a screen-printed amperometric biosensor for the determination of L-lactate dehydrogenase level.

Journal: Biosensors & bioelectronics 20020101

Title: Modulation of ornithine decarboxylase activity and mitogen-activated protein kinases in protocatechualdehyde-induced apoptosis of CTLL-2 cells.

Journal: Anticancer research 20020101

Title: Separation and determination of protocatechuic aldehyde and protocatechuic acid in Salivia miltorrhrza by capillary electrophoresis with amperometric detection.

Journal: The Analyst 20010901

Title: Properties of diphenolase from Vanilla planifolia (Andr.) shoot primordia cultured in vitro.

Journal: Journal of agricultural and food chemistry 20010701

Title: Voltammetric biosensors for the determination of formate and glucose-6-phosphate based on the measurement of dehydrogenase-generated NADH and NADPH.

Journal: Biosensors & bioelectronics 20010501

Title: 1,1-Diphenyl-2-picrylhydrazyl radical-scavenging active compounds from greater cardamom (Amomum subulatum Roxb.).

Journal: Journal of nutritional science and vitaminology 20010401

Title: [Determination of protocatechualdehyde in yu xue bi granula].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010101

Title: Induction of apoptosis in CTLL-2 cells by protocatechualdehyde.

Journal: Anticancer research 20010101

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Tags:139-85-5 Molecular Formula|139-85-5 MDL|139-85-5 SMILES|139-85-5 3,4-Dihydroxybenzaldehyde |Organic_Building_Blocks