Name: Name:Sieber linker
Brand: AABLOCKS
SKU: AA0033N8
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0033N8

Chemical Name: Sieber linker

CAS Number: 3722-51-8

Molecular Formula: C13H8O3

Molecular Weight: 212.2008

MDL Number: MFCD00604748

SMILES: Oc1ccc2c(c1)oc1c(c2=O)cccc1

Properties

BP: 403.9°C at 760 mmHg

Form: Solid

MP: 243 °C

Storage: Inert atmosphere;-20 ℃;

Complexity: 289

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 16

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

XLogP3: 3.2

Downstream Synthesis Route

3722-51-8

108-24-7

87504-09-4

[1]Lin;Liou;Ko;Teng[JournalofPharmaceuticalSciences,1993,vol.82,#1,p.11-16]

[2]v.Kostanecki;Rutishauser[ChemischeBerichte,1892,vol.25,p.1649]

13087-18-8

3722-51-8

[1]Locationinpatent:experimentalpartZhang,Xiaojin;Li,Xiang;Sun,Haopeng;Jiang,Zhengyu;Tao,Lei;Gao,Yuan;Guo,Qinglong;You,Qidong[OrganicandBiomolecularChemistry,2012,vol.10,#16,p.3288-3299]

[2]Locationinpatent:experimentalpartZhang,Xiao-Jin;Ye,Suo-Fu;Zhang,Yu;Meng,Hu-Yan;Zhang,Ming-Qian;Gao,Wen-Lei;You,Qi-Dong[SyntheticCommunications,2012,vol.42,#20,p.2952-2958]

[3]Zhang,Xiaojin;Li,Xiang;Tao,Lei;Gao,Yuan;Gong,Dandan;Xi,Meiyang;Xu,Xiaoli;Guo,Qinglong;You,Qidong;Ye,Suofu;Zhang,Yu;Meng,Huyan;Zhang,Mingqian;Gao,Wenlei[MedicinalChemistry,2012,vol.8,#6,p.1012-1025,14]

[4]Daviesetal.[JournalofOrganicChemistry,1958,vol.23,p.307]

3722-52-9

3722-51-8

[1]Sato;Dan;Onuma;Tanaka;Koga[ChemicalandPharmaceuticalBulletin,1990,vol.38,#5,p.1266-1277]

[2]Lin;Liou;Ko;Teng[JournalofPharmaceuticalSciences,1993,vol.82,#1,p.11-16]

[3]Fernandes,Carla;Masawang,Kamonporn;Tiritan,MariaElizabeth;Sousa,Emília;DeLima,Virgínia;Afonso,Carlos;Bousbaa,Hassan;Sudprasert,Wanwisa;Pedro,Madalena;Pinto,MadalenaM.[BioorganicandMedicinalChemistry,2014,vol.22,#3,p.1049-1062]

[4]Mittal;Seshadri[JournalOfScientificandIndustrialResearch,1955,vol.14B,p.76]

[5]Mauthner[1943,vol.62,p.360,363,365][Chem.Abstr.,1948,p.1267]

[6]Somlai,Csaba;Nyerges,Levente;Penke,Botond;Hegyes,Peter;Voelter,Wolfgang[JournalfurPraktischeChemie-Chemiker-Zeitung,1994,vol.336,#5,p.429-433]

[7]Locationinpatent:experimentalpartCheng,Jen-Hao;Huang,A-Mei;Hour,Tzyh-Chyuan;Yang,Shyh-Chyun;Pu,Yeong-Shiau;Lin,Chun-Nan[EuropeanJournalofMedicinalChemistry,2011,vol.46,#4,p.1222-1231]

[8]Waszkielewicz,AnnaM.;Słoczyńska,Karolina;Pękala,Elżbieta;Żmudzki,Paweł;Siwek,Agata;Gryboś,Anna;Marona,Henryk[ChemicalBiologyandDrugDesign,2017,vol.89,#3,p.339-352]

[9]Popiół,Justyna;Gunia-Krzyżak,Agnieszka;Słoczyńska,Karolina;Koczurkiewicz-Adamczyk,Paulina;Piska,Kamil;Wójcik-Pszczoła,Katarzyna;Żelaszczyk,Dorota;Krupa,Anna;Żmudzki,Paweł;Marona,Henryk;Pękala,Elżbieta[InternationalJournalofMolecularSciences,2021,vol.22,#1,p.1-23]

33077-87-1

3722-51-8

131-53-3

[1]VanAllan[JournalofOrganicChemistry,1958,vol.23,p.1679,1682]

5715-02-6

108-46-3

3722-51-8

[1]Atkinson;Heilbron[JournaloftheChemicalSociety,1926,p.2690]

Literature fold

Title: Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs).

Journal: Bioorganic & medicinal chemistry20021101

3722-51-8 | Sieber linker