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461-82-5,MFCD00041314
Catalog No.:AA0033R8

461-82-5 | 4-(Trifluoromethoxy)aniline

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10g
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$6.00   $4.00
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25g
98%
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0033R8
Chemical Name:
4-(Trifluoromethoxy)aniline
CAS Number:
461-82-5
Molecular Formula:
C7H6F3NO
Molecular Weight:
177.1238
MDL Number:
MFCD00041314
SMILES:
FC(Oc1ccc(cc1)N)(F)F
Properties
Properties
 
BP:
192.4°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.463(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
140  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.2  

Literature

Title: Triarylmethanes, a new class of cx50 inhibitors.

Journal: Frontiers in pharmacology 20120101

Title: 2,5-Dimethyl-3-[4-(trifluoro-meth-oxy)anilino]-cyclo-hex-2-enone.

Journal: Acta crystallographica. Section E, Structure reports online 20110301

Title: tert-Butyl 6-methyl-2-oxo-4-[4-(trifluoro-meth-oxy)anilino]cyclo-hex-3-ene-1-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Expanding the diversity of allosteric bcr-abl inhibitors.

Journal: Journal of medicinal chemistry 20101014

Title: Synthesis of 1-(4-trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles via chain heterocyclization.

Journal: Molecules (Basel, Switzerland) 20100223

Title: Trifluoromethoxy substituted anilines: metalation as the key step for structural elaboration.

Journal: The Journal of organic chemistry 20030613

Title: The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

Journal: Journal of pharmaceutical and biomedical analysis 20020601

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