586-95-8,MFCD00006442
Catalog No.:AA0033ZM

586-95-8 | 4-Pyridinemethanol

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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0033ZM
Chemical Name:
4-Pyridinemethanol
CAS Number:
586-95-8
Molecular Formula:
C6H7NO
Molecular Weight:
109.1259
MDL Number:
MFCD00006442
SMILES:
OCc1ccncc1
Properties
Properties
 
BP:
107-110°C at 760 mmHg  
Form:
Solid  
MP:
52-56 °C(lit.)  
Refractive Index:
1.5040 (estimate)  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
59.5  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.1  

Upstream Synthesis Route

[1]JournalfuerPraktischeChemie(Leipzig),1938,vol.<2>151,p.65,79

[2]Patent:US2003/55244,2003,A1,

[1]Patent:US4243807,1981,A,

[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.2031-2046

[1]Synthesis,2003,#7,p.1055-1064

[2]GreenChemistry,2014,vol.16,#4,p.2164-2173

[1]ChemMedChem,2015,vol.10,#11,p.1875-1883

Downstream Synthesis Route

[1]JournalofChemicalResearch,2007,p.252-256

[2]ChineseJournalofChemistry,2020

[3]BulletinoftheChemicalSocietyofJapan,1991,vol.64,p.796-800

[4]Phosphorus,SulfurandSiliconandtheRelatedElements,2007,vol.182,p.589-593

[5]TetrahedronLetters,1999,vol.40,p.1635-1636

[6]Chemistry-AnAsianJournal,2016,vol.11,p.3084-3089

[7]Synthesis,1988,p.868-871

[8]EuropeanJournalofOrganicChemistry,2014,vol.2014,p.395-402

[9]Synlett,2013,vol.24,p.2451-2453

[10]AppliedCatalysisA:General,2018,vol.558,p.26-33

[11]SyntheticCommunications,2004,vol.34,p.2835-2842

[12]JournalofOrganicChemistry,2002,vol.67,p.7075-7079

[13]NewJournalofChemistry,2017,vol.41,p.2372-2377

[14]InorganicChemistry,2020,vol.59,p.254-263

[15]JournalofChemicalResearch,2006,p.188-191

[16]TetrahedronLetters,2005,vol.46,p.8483-8486

[17]TetrahedronLetters,2013,vol.54,p.3882-3885

[18]NewJournalofChemistry,2017,vol.41,p.13377-13381

[19]NewJournalofChemistry,2019,vol.43,p.19415-19421

[20]Synlett,2018,vol.29,p.1152-1156

[21]CatalysisCommunications,2017,vol.101,p.98-101

[22]CatalysisCommunications,2017,vol.95,p.6-11

[23]ChemischeBerichte,1990,vol.123,p.1357-1364

[24]JustusLiebigsAnnalenderChemie,1958,vol.613,p.171,179

[25]PharmaceuticalBulletin,1955,vol.3,p.232

[26]JustusLiebigsAnnalenderChemie,1958,vol.613,p.171,179

[27]JustusLiebigsAnnalenderChemie,1958,vol.613,p.171,179

[28]RecueildesTravauxChimiquesdesPays-Bas,1952,vol.71,p.970,974

[29]PharmaceuticalBulletin,1954,vol.2,p.341

[30]JournalofOrganicChemistryUSSR(EnglishTranslation),1985,vol.21,p.588-591    ZhurnalOrganicheskoiKhimii,1985,vol.21,p.649-652

[31]JournalofOrganicChemistry,1996,vol.61,p.1467-1472

[32]EuropeanJournalofOrganicChemistry,2010,p.3445-3448

[33]TetrahedronLetters,2011,vol.52,p.3868-3871

[34]ChemMedChem,2014,vol.9,p.590-601

[35]JournaloftheChineseChemicalSociety,2014,vol.61,p.517-520

[36]EuropeanJournalofOrganicChemistry,2014,vol.2014,p.395-402

[37]RSCAdvances,2016,vol.6,p.106769-106777

[38]Patent:CN107311918,2017,A.Locationinpatent:Paragraph0032;0036;0041;0046

[39]TetrahedronLetters,2018,vol.59,p.247-251

[40]NewJournalofChemistry,2018,vol.42,p.11381-11389

[41]AppliedOrganometallicChemistry,2018,vol.32

[42]ZeitschriftfurAnorganischeundAllgemeineChemie,2018,vol.644,p.692-699

[43]NewJournalofChemistry,2018,vol.42,p.16523-16532

[44]InorganicaChimicaActa,2019,vol.486,p.476-482

[45]ChemBioChem,2019,vol.20,p.276-281

[46]Patent:CN106866508,2019,B.Locationinpatent:Paragraph0015-0018

[47]InorganicChemistryCommunications,2020,vol.112

[48]Chemistry-AnAsianJournal,2020,vol.15,p.926-932

[49]ElectrochimicaActa,2020,vol.354

[50]Molecularcatalysis,2020,vol.494

[51]CatalysisCommunications,2020,vol.145

[52],2020,vol.10,p.7699-7709

[1]Patent:WO2007/104783,2007,A2.Locationinpatent:Page/Pagecolumn49

[2]Phosphorus,SulfurandSiliconandtheRelatedElements,1995,vol.102,p.45-50

[3]SyntheticCommunications,2012,vol.42,p.1731-1745

[4]Molecules,2011,vol.16,p.5665-5673

[5]ActaChimicaAcademiaeScientiarumHungaricae,1959,vol.19,p.205,213

[6]Chemicalandpharmaceuticalbulletin,1958,vol.6,p.467,470

[7]JournaloftheAmericanChemicalSociety,1951,vol.73,p.4925

[8]JournalofMedicinalChemistry,1998,vol.41,p.2146-2163

[9]Patent:US4385058,1983,A

[10]ACSMedicinalChemistryLetters,2013,vol.4,p.278-282

[11]Patent:CN111187218,2020,A.Locationinpatent:Paragraph0227-0229

[12]Patent:CN111253317,2020,A.Locationinpatent:Paragraph0228-0230

[1]Thellend;Battioni;Sanderson;Mansuy[Synthesis,1997,#12,p.1387-1388]

[2]McKillop,Alexander;Kemp,Duncan[Tetrahedron,1989,vol.45,#11,p.3299-3306]

[3]Bixler;Niemann[JournalofOrganicChemistry,1958,vol.23,p.575,580]Furukawa[YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1958,vol.78,p.957,959][Chem.Abstr.,1959,p.3219]

[1]JournalfurpraktischeChemie(Leipzig1954),1938,vol.<2>151,p.65,79

Literature

Title: Stabilization of high-valence ruthenium with silicotungstate ligands: preparation, structural characterization, and redox studies of ruthenium(III)-substituted α-Keggin-type silicotungstates with pyridine ligands, [SiW11O39Ru(III)(Py)]5-.

Journal: Chemistry, an Asian journal 20120601

Title: A pilot randomised trial of induced blood-stage Plasmodium falciparum infections in healthy volunteers for testing efficacy of new antimalarial drugs.

Journal: PloS one 20110101

Title: Binding of activated isoniazid with acetyl-CoA carboxylase from Mycobacterium tuberculosis.

Journal: Bioinformation 20110101

Title: Noncovalent synthesis of hierarchical zinc phosphates from a single Zn(4)O(12)P(4) double-four-ring building block: dimensionality control through the choice of auxiliary ligands.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100118

Title: The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.

Journal: European journal of medicinal chemistry 20100101

Title: Synthesis and Structural Characterization of a Metal Cluster and a Coordination Polymer Based on the [Mn(6)(mu(4)-O)(2)] Unit.

Journal: Bioinorganic chemistry and applications 20100101

Title: 4-Pyridyl carbonyl compounds as thrips lures: effectiveness for Western flower thrips in y-tube bioassays.

Journal: Journal of agricultural and food chemistry 20080813

Title: Supramolecular allosteric cofacial porphyrin complexes.

Journal: Journal of the American Chemical Society 20061220

Title: Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.

Journal: The FEBS journal 20060101

Title: Synthesis, characterization and biological activity of trans-platinum(II) and trans-platinum(IV) complexes with 4-hydroxymethylpyridine.

Journal: Chembiochem : a European journal of chemical biology 20051101

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Tags:586-95-8 Molecular Formula|586-95-8 MDL|586-95-8 SMILES|586-95-8 4-Pyridinemethanol
Catalog No.: AA0033ZM
586-95-8,MFCD00006442
586-95-8 | 4-Pyridinemethanol
Pack Size: 1g
Purity: 99% HPLC
in stock
$6.00 $4.00
Pack Size: 5g
Purity: 99% HPLC
in stock
$8.00 $6.00
Pack Size: 10g
Purity: 98%
in stock
$12.00 $8.00
Pack Size: 25g
Purity: 99% HPLC
in stock
$24.00 $17.00
Pack Size: 100g
Purity: 99% HPLC
in stock
$92.00 $64.00
Pack Size: 500g
Purity: 99% HPLC
in stock
$329.00 $231.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA0033ZM
Chemical Name: 4-Pyridinemethanol
CAS Number: 586-95-8
Molecular Formula: C6H7NO
Molecular Weight: 109.1259
MDL Number: MFCD00006442
SMILES: OCc1ccncc1
Properties
BP: 107-110°C at 760 mmHg  
Form: Solid  
MP: 52-56 °C(lit.)  
Refractive Index: 1.5040 (estimate)  
Stability: Hygroscopic  
Storage: Inert atmosphere;2-8℃;  
Complexity: 59.5  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 8  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 1  
XLogP3: 0.1  
Upstream Synthesis Route
586-95-8    6457-49-4 

[1]JournalfuerPraktischeChemie(Leipzig),1938,vol.<2>151,p.65,79

[2]Patent:US2003/55244,2003,A1,

586-95-8    63608-14-0    6457-49-4 

[1]Patent:US4243807,1981,A,

1003-67-4    108-24-7    1121-19-3    586-95-8 

[1]JournalofMedicinalChemistry,1987,vol.30,#11,p.2031-2046

586-95-8    67-56-1    2459-09-8 

[1]Synthesis,2003,#7,p.1055-1064

[2]GreenChemistry,2014,vol.16,#4,p.2164-2173

586-95-8    69583-00-2 

[1]ChemMedChem,2015,vol.10,#11,p.1875-1883

Downstream Synthesis Route
586-95-8    872-85-5 

[1]JournalofChemicalResearch,2007,p.252-256

[2]ChineseJournalofChemistry,2020

[3]BulletinoftheChemicalSocietyofJapan,1991,vol.64,p.796-800

[4]Phosphorus,SulfurandSiliconandtheRelatedElements,2007,vol.182,p.589-593

[5]TetrahedronLetters,1999,vol.40,p.1635-1636

[6]Chemistry-AnAsianJournal,2016,vol.11,p.3084-3089

[7]Synthesis,1988,p.868-871

[8]EuropeanJournalofOrganicChemistry,2014,vol.2014,p.395-402

[9]Synlett,2013,vol.24,p.2451-2453

[10]AppliedCatalysisA:General,2018,vol.558,p.26-33

[11]SyntheticCommunications,2004,vol.34,p.2835-2842

[12]JournalofOrganicChemistry,2002,vol.67,p.7075-7079

[13]NewJournalofChemistry,2017,vol.41,p.2372-2377

[14]InorganicChemistry,2020,vol.59,p.254-263

[15]JournalofChemicalResearch,2006,p.188-191

[16]TetrahedronLetters,2005,vol.46,p.8483-8486

[17]TetrahedronLetters,2013,vol.54,p.3882-3885

[18]NewJournalofChemistry,2017,vol.41,p.13377-13381

[19]NewJournalofChemistry,2019,vol.43,p.19415-19421

[20]Synlett,2018,vol.29,p.1152-1156

[21]CatalysisCommunications,2017,vol.101,p.98-101

[22]CatalysisCommunications,2017,vol.95,p.6-11

[23]ChemischeBerichte,1990,vol.123,p.1357-1364

[24]JustusLiebigsAnnalenderChemie,1958,vol.613,p.171,179

[25]PharmaceuticalBulletin,1955,vol.3,p.232

[26]JustusLiebigsAnnalenderChemie,1958,vol.613,p.171,179

[27]JustusLiebigsAnnalenderChemie,1958,vol.613,p.171,179

[28]RecueildesTravauxChimiquesdesPays-Bas,1952,vol.71,p.970,974

[29]PharmaceuticalBulletin,1954,vol.2,p.341

[30]JournalofOrganicChemistryUSSR(EnglishTranslation),1985,vol.21,p.588-591    ZhurnalOrganicheskoiKhimii,1985,vol.21,p.649-652

[31]JournalofOrganicChemistry,1996,vol.61,p.1467-1472

[32]EuropeanJournalofOrganicChemistry,2010,p.3445-3448

[33]TetrahedronLetters,2011,vol.52,p.3868-3871

[34]ChemMedChem,2014,vol.9,p.590-601

[35]JournaloftheChineseChemicalSociety,2014,vol.61,p.517-520

[36]EuropeanJournalofOrganicChemistry,2014,vol.2014,p.395-402

[37]RSCAdvances,2016,vol.6,p.106769-106777

[38]Patent:CN107311918,2017,A.Locationinpatent:Paragraph0032;0036;0041;0046

[39]TetrahedronLetters,2018,vol.59,p.247-251

[40]NewJournalofChemistry,2018,vol.42,p.11381-11389

[41]AppliedOrganometallicChemistry,2018,vol.32

[42]ZeitschriftfurAnorganischeundAllgemeineChemie,2018,vol.644,p.692-699

[43]NewJournalofChemistry,2018,vol.42,p.16523-16532

[44]InorganicaChimicaActa,2019,vol.486,p.476-482

[45]ChemBioChem,2019,vol.20,p.276-281

[46]Patent:CN106866508,2019,B.Locationinpatent:Paragraph0015-0018

[47]InorganicChemistryCommunications,2020,vol.112

[48]Chemistry-AnAsianJournal,2020,vol.15,p.926-932

[49]ElectrochimicaActa,2020,vol.354

[50]Molecularcatalysis,2020,vol.494

[51]CatalysisCommunications,2020,vol.145

[52],2020,vol.10,p.7699-7709

586-95-8    10445-91-7 

[1]Patent:WO2007/104783,2007,A2.Locationinpatent:Page/Pagecolumn49

[2]Phosphorus,SulfurandSiliconandtheRelatedElements,1995,vol.102,p.45-50

[3]SyntheticCommunications,2012,vol.42,p.1731-1745

[4]Molecules,2011,vol.16,p.5665-5673

[5]ActaChimicaAcademiaeScientiarumHungaricae,1959,vol.19,p.205,213

[6]Chemicalandpharmaceuticalbulletin,1958,vol.6,p.467,470

[7]JournaloftheAmericanChemicalSociety,1951,vol.73,p.4925

[8]JournalofMedicinalChemistry,1998,vol.41,p.2146-2163

[9]Patent:US4385058,1983,A

[10]ACSMedicinalChemistryLetters,2013,vol.4,p.278-282

[11]Patent:CN111187218,2020,A.Locationinpatent:Paragraph0227-0229

[12]Patent:CN111253317,2020,A.Locationinpatent:Paragraph0228-0230

586-95-8    22346-75-4 

[1]Thellend;Battioni;Sanderson;Mansuy[Synthesis,1997,#12,p.1387-1388]

[2]McKillop,Alexander;Kemp,Duncan[Tetrahedron,1989,vol.45,#11,p.3299-3306]

[3]Bixler;Niemann[JournalofOrganicChemistry,1958,vol.23,p.575,580]Furukawa[YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1958,vol.78,p.957,959][Chem.Abstr.,1959,p.3219]

101990-69-6    586-95-8 

[1]JournalfurpraktischeChemie(Leipzig1954),1938,vol.<2>151,p.65,79

Literature fold

Title: Stabilization of high-valence ruthenium with silicotungstate ligands: preparation, structural characterization, and redox studies of ruthenium(III)-substituted α-Keggin-type silicotungstates with pyridine ligands, [SiW11O39Ru(III)(Py)]5-.

Journal: Chemistry, an Asian journal20120601

Title: A pilot randomised trial of induced blood-stage Plasmodium falciparum infections in healthy volunteers for testing efficacy of new antimalarial drugs.

Journal: PloS one20110101

Title: Binding of activated isoniazid with acetyl-CoA carboxylase from Mycobacterium tuberculosis.

Journal: Bioinformation20110101

Title: Noncovalent synthesis of hierarchical zinc phosphates from a single Zn(4)O(12)P(4) double-four-ring building block: dimensionality control through the choice of auxiliary ligands.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20100118

Title: The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.

Journal: European journal of medicinal chemistry20100101

Title: Synthesis and Structural Characterization of a Metal Cluster and a Coordination Polymer Based on the [Mn(6)(mu(4)-O)(2)] Unit.

Journal: Bioinorganic chemistry and applications20100101

Title: 4-Pyridyl carbonyl compounds as thrips lures: effectiveness for Western flower thrips in y-tube bioassays.

Journal: Journal of agricultural and food chemistry20080813

Title: Supramolecular allosteric cofacial porphyrin complexes.

Journal: Journal of the American Chemical Society20061220

Title: Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.

Journal: The FEBS journal20060101

Title: Synthesis, characterization and biological activity of trans-platinum(II) and trans-platinum(IV) complexes with 4-hydroxymethylpyridine.

Journal: Chembiochem : a European journal of chemical biology20051101

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