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70356-09-1,MFCD00210252
Catalog No.:AA00342H

70356-09-1 | 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione

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10g
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$7.00   $5.00
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25g
98%
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$9.00   $7.00
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500g
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$114.00   $80.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00342H
Chemical Name:
1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione
CAS Number:
70356-09-1
Molecular Formula:
C20H22O3
Molecular Weight:
310.3869
MDL Number:
MFCD00210252
SMILES:
COc1ccc(cc1)C(=O)CC(=O)c1ccc(cc1)C(C)(C)C
NSC Number:
758680
Properties
Properties
 
BP:
463.6°C at 760 mmHg  
Form:
Solid  
MP:
81-84 °C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
405  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
4.8  

Literature

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Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170301

Title: Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.

Journal: Toxicology and applied pharmacology 20150301

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Photophysical properties of dioctyl 4-methoxybenzylidenemalonate: UV-B absorber.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20121001

Title: Lipid nanoparticles based on butyl-methoxydibenzoylmethane: in vitro UVA blocking effect.

Journal: Nanotechnology 20120810

Title: Addition of UVA-absorber butyl methoxy dibenzoylmethane to topical ketoprofen formulation reduces ketoprofen-photoallergic reaction.

Journal: Journal of photochemistry and photobiology. B, Biology 20120801

Title: Erbium:YAG laser resurfacing increases skin permeability and the risk of excessive absorption of antibiotics and sunscreens: the influence of skin recovery on drug absorption.

Journal: Toxicology letters 20120601

Title: Ecotoxicological effect characterisation of widely used organic UV filters.

Journal: Environmental pollution (Barking, Essex : 1987) 20120401

Title: Measuring sunscreen protection against solar-simulated radiation-induced structural radical damage to skin using ESR/spin trapping: development of an ex vivo test method.

Journal: Free radical research 20120301

Title: Polyamide nanocapsules and nano-emulsions containing Parsol® MCX and Parsol® 1789: in vitro release, ex vivo skin penetration and photo-stability studies.

Journal: Pharmaceutical research 20120201

Title: Quantification of sunscreen ethylhexyl triazone in topical skin-care products by normal-phase TLC/densitometry.

Journal: TheScientificWorldJournal 20120101

Title: Is there truly no benefit with sunscreen use and Basal cell carcinoma? A critical review of the literature and the application of new sunscreen labeling rules to real-world sunscreen practices.

Journal: Journal of skin cancer 20120101

Title: Photodegradation of (-)-epigallocatechin-3-gallate in topical cream formulations and its photostabilization.

Journal: Journal of pharmaceutical and biomedical analysis 20111205

Title: Photoexcited triplet states of new UV absorbers, cinnamic acid 2-methylphenyl esters.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111201

Title: Synthesis and evaluation of novel tetrapropoxycalix[4]arene enones and cinnamates for protection from ultraviolet radiation.

Journal: Journal of photochemistry and photobiology. B, Biology 20111005

Title: Photochemical and photophysical properties of dibenzoylmethane derivatives within protein.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110901

Title: Differential scanning calorimetry studies on sunscreen loaded solid lipid nanoparticles prepared by the phase inversion temperature method.

Journal: International journal of pharmaceutics 20110830

Title: UV protection afforded by gel-trapped TiO2 particles.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110701

Title: A rapid High Performance Liquid Chromatographic (HPLC) method for the simultaneous determination of seven UV filters found in sunscreen and cosmetics.

Journal: International journal of cosmetic science 20110401

Title: Microencapsulation of a cyclodextrin complex of the UV filter, butyl methoxydibenzoylmethane: in vivo skin penetration studies.

Journal: Journal of pharmaceutical and biomedical analysis 20110125

Title: Encapsulation of the UV filters ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles: effect on in vivo human skin permeation.

Journal: Skin pharmacology and physiology 20110101

Title: Pathways of lateral spreading.

Journal: Skin pharmacology and physiology 20110101

Title: The next frontier of sunscreen protection: beyond sunscreens.

Journal: Skinmed 20110101

Title: Mycosporine and mycosporine-like amino acids: A paramount tool against ultra violet irradiation.

Journal: Pharmacognosy reviews 20110101

Title: Potential of herbs in skin protection from ultraviolet radiation.

Journal: Pharmacognosy reviews 20110101

Title: Characterization of the UVA protection provided by avobenzone, zinc oxide, and titanium dioxide in broad-spectrum sunscreen products.

Journal: American journal of clinical dermatology 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Determination of organic UV filters in water by stir bar sorptive extraction and direct analysis in real-time mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20100501

Title: Filter-filter interactions. Photostabilization, triplet quenching and reactivity with singlet oxygen.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100401

Title: A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen.

Journal: The British journal of dermatology 20100301

Title: Polymorphism and reversible mechanochromic luminescence for solid-state difluoroboron avobenzone.

Journal: Journal of the American Chemical Society 20100224

Title: Photostabilization effect of quercetin on the UV filter combination, butyl methoxydibenzoylmethane-octyl methoxycinnamate.

Journal: Photochemistry and photobiology 20100101

Title: True photoallergy to sunscreens is rare despite popular belief.

Journal: Dermatitis : contact, atopic, occupational, drug 20100101

Title: An Assessment of the Efficacy and Safety of CROSS Technique with 100% TCA in the Management of Ice Pick Acne Scars.

Journal: Journal of cutaneous and aesthetic surgery 20100101

Title: Optical and electron paramagnetic resonance studies of the excited states of 4-tert-butyl-4'-methoxydibenzoylmethane and 4-tert-butyl-4'-methoxydibenzoylpropane.

Journal: The journal of physical chemistry. A 20091203

Title: Photodegradation of dibenzoylmethanes: potential cause of photocontact allergy to sunscreens.

Journal: Chemical research in toxicology 20091101

Title: Identification and determination butylmethoxydibenzoylmethane in the presence benzophenone-3 and ethylhexylmethoxycinnamate in suncare preparation.

Journal: International journal of cosmetic science 20091001

Title: Evaluation of spray congealing as technique for the preparation of highly loaded solid lipid microparticles containing the sunscreen agent, avobenzone.

Journal: Journal of pharmaceutical sciences 20090801

Title: Incorporation in lipid microparticles of the UVA filter, butyl methoxydibenzoylmethane combined with the UVB filter, octocrylene: effect on photostability.

Journal: AAPS PharmSciTech 20090601

Title: Co-loading of a photostabilizer with the sunscreen agent, butyl methoxydibenzoylmethane in solid lipid microparticles.

Journal: Drug development and industrial pharmacy 20090201

Title: A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions.

Journal: Cutis 20090201

Title: A blocked diketo form of avobenzone: photostability, photosensitizing properties and triplet quenching by a triazine-derived UVB-filter.

Journal: Photochemistry and photobiology 20090101

Title: Role of UV light in photodamage, skin aging, and skin cancer: importance of photoprotection.

Journal: American journal of clinical dermatology 20090101

Title: Impact on facial rejuvenation with dermatological preparations.

Journal: Clinical interventions in aging 20090101

Title: Addressing technical challenges associated with the FDA's proposed rules for the UVA in vitro testing procedure.

Journal: Journal of cosmetic science 20090101

Title: In vitro assessments of UVA protection by popular sunscreens available in the United States.

Journal: Journal of the American Academy of Dermatology 20081201

Title: Photoallergic contact dermatitis caused by ultraviolet filters in different sunscreens.

Journal: International journal of dermatology 20081101

Title: Influence of hydroxypropyl-beta-cyclodextrin on transdermal penetration and photostability of avobenzone.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601

Title: Rationale for sunscreen development.

Journal: Journal of the American Academy of Dermatology 20080501

Title: Assessing retinol stability in a hydroquinone 4%/retinol 0.3% cream in the presence of antioxidants and sunscreen under simulated-use conditions: a pilot study.

Journal: Clinical therapeutics 20080301

Title: In vivo and in vitro skin permeation of butyl methoxydibenzoylmethane from lipospheres.

Journal: Skin pharmacology and physiology 20080101

Title: Prevention of polymorphic light eruption with a sunscreen of very high protection level against UVB and UVA radiation under standardized photodiagnostic conditions.

Journal: Acta dermato-venereologica 20080101

Title: Photostability and efficacy studies of topical formulations containing UV-filters combination and vitamins A, C and E.

Journal: International journal of pharmaceutics 20071001

Title: Degradation kinetics of butylmethoxydibenzoylmethane (avobenzone) in aqueous solution.

Journal: Die Pharmazie 20071001

Title: Mexoryl: a review of an ultraviolet a filter.

Journal: Plastic and reconstructive surgery 20070915

Title: I've heard there's a new sunscreen that's supposed to offer better skin protection. Can you tell me more?

Journal: Mayo Clinic women's healthsource 20070601

Title: A new sunscreen agent.

Journal: The Medical letter on drugs and therapeutics 20070521

Title: Transient enol isomers of dibenzoylmethane and avobenzone as efficient hydrogen donors toward a nitroxide pre-fluorescent probe.

Journal: Photochemistry and photobiology 20070101

Title: OTC product: Anthelios SX.

Journal: Journal of the American Pharmacists Association : JAPhA 20070101

Title: [Simultaneous determination of 9 ultraviolet absorbers in cosmetics by high-performance liquid chromatography].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Interactions between different solar UVB/UVA filters contained in commercial suncreams and consequent loss of UV protection.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060901

Title: Encapsulation in lipospheres of the complex between butyl methoxydibenzoylmethane and hydroxypropyl-beta-cyclodextrin.

Journal: International journal of pharmaceutics 20060831

Title: Influence of liposphere preparation on butyl-methoxydibenzoylmethane photostability.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Sun protection strength of a hydroquinone 4%/retinol 0.3% preparation containing sunscreens.

Journal: Journal of drugs in dermatology : JDD 20060401

Title: Changes in ultraviolet absorbance and hence in protective efficacy against lipid peroxidation of organic sunscreens after UVA irradiation.

Journal: Journal of photochemistry and photobiology. B, Biology 20060301

Title: Evaluation of the photostability of different UV filter combinations in a sunscreen.

Journal: International journal of pharmaceutics 20060113

Title: Design of a photostabilizer having built-in antioxidant functionality and its utility in obtaining broad-spectrum sunscreen formulations.

Journal: Photochemistry and photobiology 20060101

Title: The FDA approves new over-the-counter sunscreen.

Journal: FDA consumer 20060101

Title: Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050201

Title: Unexpected photolysis of the sunscreen octinoxate in the presence of the sunscreen avobenzone.

Journal: Photochemistry and photobiology 20050101

Title: A new long-chain UV absorber derived from 4-tert-butyl-4'-methoxydibenzoylmethane: absorbance stability under solar irradiation.

Journal: Journal of cosmetic science 20050101

Title: Sunscreen penetration of human skin and related keratinocyte toxicity after topical application.

Journal: Skin pharmacology and physiology 20050101

Title: Lack of in vitro protection by a common sunscreen ingredient on UVA-induced cytotoxicity in keratinocytes.

Journal: Toxicology 20041015

Title: Determination of sixteen UV filters in suncare formulations by high-performance liquid chromatography.

Journal: Journal of chromatography. A 20040917

Title: Influence of cyclodextrins on in vitro human skin absorption of the sunscreen, butyl-methoxydibenzoylmethane.

Journal: International journal of pharmaceutics 20040806

Title: Lateral spreading of topically applied UV filter substances investigated by tape stripping.

Journal: Skin pharmacology and physiology 20040101

Title: Photochemical behavior of a new long-chain UV absorber derived from 4-tert-butyl-4'-methoxydibenzoylmethane.

Journal: Photochemistry and photobiology 20040101

Title: Effects of silicone emulsifiers on in vitro skin permeation of sunscreens from cosmetic emulsions.

Journal: Journal of cosmetic science 20040101

Title: Non-invasive in vivo determination of UVA efficacy of sunscreens using diffuse reflectance spectroscopy.

Journal: Photodermatology, photoimmunology & photomedicine 20030801

Title: Skin penetration and sun protection factor of five UV filters: effect of the vehicle.

Journal: Skin pharmacology and applied skin physiology 20030101

Title: Bioconvertible vitamin antioxidants improve sunscreen photoprotection against UV-induced reactive oxygen species.

Journal: Journal of cosmetic science 20030101

Title: Protection against UVB irradiation by natural filters extracted from lichens.

Journal: Journal of photochemistry and photobiology. B, Biology 20021101

Title: Influence of hydroxypropyl-beta-cyclodextrin on photo-induced free radical production by the sunscreen agent, butyl-methoxydibenzoylmethane.

Journal: The Journal of pharmacy and pharmacology 20021101

Title: The effects of derivatives of the nitroxide tempol on UVA-mediated in vitro lipid and protein oxidation.

Journal: Free radical biology & medicine 20020701

Title: The effect of UV absorbing sunscreens on the reflectance and the consequent protection of skin.

Journal: Photochemistry and photobiology 20020201

Title: A new model using liposomes that allow to distinguish between absorption and oxidative properties of sunscreens.

Journal: Photochemistry and photobiology 20020101

Title: Photochemical studies of 4-tert-butyl-4'-methoxydibenzoylmethane (BM-DBM).

Journal: Journal of photochemistry and photobiology. B, Biology 20011115

Title: Photostabilization of butyl methoxydibenzoylmethane (Avobenzone) and ethylhexyl methoxycinnamate by bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a new UV broadband filter.

Journal: Photochemistry and photobiology 20010901

Title: Multiple chemical sensitivities, including iatrogenic allergic contact dermatitis, in a patient with chronic actinic dermatitis: implications for management.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 19960901

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SDS
Tags:70356-09-1 Molecular Formula|70356-09-1 MDL|70356-09-1 SMILES|70356-09-1 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione |Organic_Building_Blocks