Home Amines 360-97-4
360-97-4,MFCD02181040
Catalog No.:AA003446

360-97-4 | 4-Amino-5-imidazolecarboxamide

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Purity
Availability
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5g
97%
in stock  
$7.00   $5.00
- +
25g
97%
in stock  
$16.00   $11.00
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500g
97%
in stock  
$295.00   $206.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003446
Chemical Name:
4-Amino-5-imidazolecarboxamide
CAS Number:
360-97-4
Molecular Formula:
C4H6N4O
Molecular Weight:
126.1166
MDL Number:
MFCD02181040
SMILES:
NC(=O)c1[nH]cnc1N
NSC Number:
7784
Properties
Properties
 
BP:
522.1°C at 760 mmHg  
Form:
Solid  
MP:
164-170 °C(lit.);  
Refractive Index:
1.8500 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
126  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
-0.5  

Literature

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Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: Effects of short-chain acyl-CoA dehydrogenase on cardiomyocyte apoptosis.

Journal: Journal of cellular and molecular medicine 20160701

Title: Fipronil promotes adipogenesis via AMPKα-mediated pathway in 3T3-L1 adipocytes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160601

Title: AMPK Activation Prevents and Reverses Drug-Induced Mitochondrial and Hepatocyte Injury by Promoting Mitochondrial Fusion and Function.

Journal: PloS one 20160101

Title: Resveratrol reduces morphine tolerance by inhibiting microglial activation via AMPK signalling.

Journal: European journal of pain (London, England) 20141101

Title: Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1.

Journal: Pharmacological research 20141101

Title: Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.

Journal: Bioorganic & medicinal chemistry 20131001

Title: Novel proton MR spectroscopy findings in adenylosuccinate lyase deficiency.

Journal: Journal of magnetic resonance imaging : JMRI 20130401

Title: Combination therapy with 5-amino-4-imidazolecarboxamide riboside and arsenic trioxide in acute myeloid leukemia cells involving AMPK/TSC2/mTOR pathway.

Journal: Die Pharmazie 20130201

Title: Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells.

Journal: PloS one 20130101

Title: SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions.

Journal: Science (New York, N.Y.) 20121123

Title: AMP-activated kinase relaxes agonist induced contractions in the mouse aorta via effects on PKC signaling and inhibits NO-induced relaxation.

Journal: European journal of pharmacology 20121115

Title: Impact of glucagon-like peptide-1 (7-36) amide, isosteviol and 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside on leucine-mediated α-cell dysfunction.

Journal: Diabetes, obesity & metabolism 20121101

Title: Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.

Journal: Journal of lipid research 20121101

Title: Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator.

Journal: Endocrinology 20121101

Title: AMP-activated protein kinase stimulates myostatin expression in C2C12 cells.

Journal: Biochemical and biophysical research communications 20121012

Title: AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway.

Journal: Melanoma research 20121001

Title: AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121001

Title: Iprodione residues and dissipation rates in tobacco leaves and soil.

Journal: Bulletin of environmental contamination and toxicology 20121001

Title: The Arabidopsis F-box protein AtFBS1 interacts with 14-3-3 proteins.

Journal: Plant science : an international journal of experimental plant biology 20121001

Title: Mild stress of caffeine increased mtDNA content in skeletal muscle cells: the interplay between Ca2+ transients and nitric oxide.

Journal: Journal of muscle research and cell motility 20121001

Title: AMP-activated protein kinase upregulates glucose uptake in thyroid PCCL3 cells independent of thyrotropin.

Journal: Thyroid : official journal of the American Thyroid Association 20121001

Title: Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20120915

Title: Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression.

Journal: The Journal of nutritional biochemistry 20120901

Title: Metformin preconditioning protects Daphnia pulex from lethal hypoxic insult involving AMPK, HIF and mTOR signaling.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120901

Title: Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells.

Journal: The Journal of pharmacology and experimental therapeutics 20120901

Title: Platycodin D inhibits lipogenesis through AMPKα-PPARγ2 in 3T3-L1 cells and modulates fat accumulation in obese mice.

Journal: Planta medica 20120901

Title: Alterations of phosphoproteins in NCI-H526 small cell lung cancer cells involved in cytotoxicity of cisplatin and titanocene Y.

Journal: Neoplasia (New York, N.Y.) 20120901

Title: Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation.

Journal: Biochemistry 20120821

Title: The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism.

Journal: American journal of physiology. Endocrinology and metabolism 20120815

Title: Phosphorylation of adipose triglyceride lipase Ser(404) is not related to 5'-AMPK activation during moderate-intensity exercise in humans.

Journal: American journal of physiology. Endocrinology and metabolism 20120815

Title: Augmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphate.

Journal: Molecular pharmacology 20120801

Title: Adiponectin inhibits KISS1 gene transcription through AMPK and specificity protein-1 in the hypothalamic GT1-7 neurons.

Journal: The Journal of endocrinology 20120801

Title: AMPK activation by AICAR inhibits myogenic differentiation and myostatin expression in cattle.

Journal: Cell and tissue research 20120801

Title: Effect of adenosine-regulating agent acadesine on morbidity and mortality associated with coronary artery bypass grafting: the RED-CABG randomized controlled trial.

Journal: JAMA 20120711

Title: Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.

Journal: The Journal of biological chemistry 20120706

Title: AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney.

Journal: British journal of pharmacology 20120701

Title: Intracellular disposition of methotrexate in acute lymphoblastic leukemia in children.

Journal: Current drug metabolism 20120701

Title: Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies.

Journal: Expert opinion on therapeutic targets 20120701

Title: Epinephrine and AICAR-induced PGC-1α mRNA expression is intact in skeletal muscle from rats fed a high-fat diet.

Journal: American journal of physiology. Cell physiology 20120615

Title: Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells.

Journal: The Journal of biological chemistry 20120608

Title: Aminoimidazole carboxamide ribonucleotide ameliorates experimental autoimmune uveitis.

Journal: Investigative ophthalmology & visual science 20120601

Title: In mammalian muscle, SIRT3 is present in mitochondria and not in the nucleus; and SIRT3 is upregulated by chronic muscle contraction in an adenosine monophosphate-activated protein kinase-independent manner.

Journal: Metabolism: clinical and experimental 20120501

Title: PDGF-induced airway smooth muscle proliferation is associated with Human antigen R activation and could be weakened by AMPK activation.

Journal: Molecular biology reports 20120501

Title: Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20120501

Title: Suppression of adipose lipolysis by long-chain fatty acid analogs.

Journal: Journal of lipid research 20120501

Title: A novel method to measure glucose uptake and myosin heavy chain isoform expression of single fibers from rat skeletal muscle.

Journal: Diabetes 20120501

Title: AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol.

Journal: Endocrinology 20120501

Title: Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism.

Journal: Mechanisms of ageing and development 20120501

Title: Accessible high-throughput virtual screening molecular docking software for students and educators.

Journal: PLoS computational biology 20120501

Title: AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.

Journal: Circulation research 20120427

Title: Determination of famoxadone, fenamidone, fenhexamid and iprodione residues in greenhouse tomatoes.

Journal: Pest management science 20120401

Title: Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways.

Journal: Cell biochemistry and biophysics 20120401

Title: Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι.

Journal: Metabolism: clinical and experimental 20120401

Title: AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.

Journal: The Biochemical journal 20120401

Title: AMP-activated protein kinase activator AICAR acutely lowers blood pressure and relaxes isolated resistance arteries of hypertensive rats.

Journal: Journal of hypertension 20120401

Title: Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling.

Journal: Cancer prevention research (Philadelphia, Pa.) 20120401

Title: Cilostazol Decreases Ethanol-Mediated TNFalpha Expression in RAW264.7 Murine Macrophage and in Liver from Binge Drinking Mice.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20120401

Title: Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells.

Journal: Biochemical and biophysical research communications 20120323

Title: Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1.

Journal: The Journal of biological chemistry 20120309

Title: Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus.

Journal: Endocrinology 20120301

Title: Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011 (part 2).

Journal: Journal of cachexia, sarcopenia and muscle 20120301

Title: AMP-activated protein kinase connects cellular energy metabolism to KATP channel function.

Journal: Journal of molecular and cellular cardiology 20120201

Title: Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice.

Journal: Hepatology (Baltimore, Md.) 20120201

Title: Activation of AMP-kinase by AICAR induces apoptosis of DU-145 prostate cancer cells through generation of reactive oxygen species and activation of c-Jun N-terminal kinase.

Journal: International journal of oncology 20120201

Title: AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1.

Journal: Journal of cellular biochemistry 20120201

Title: 5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation.

Journal: Stem cells (Dayton, Ohio) 20120201

Title: Novel synthetic methods for N-cyano-1H-imidazole-4-carboxamides and their fungicidal activity.

Journal: Bioorganic & medicinal chemistry letters 20120201

Title: AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.

Journal: Nature medicine 20120201

Title: Antiproliferative activity of levobupivacaine and aminoimidazole carboxamide ribonucleotide on human cancer cells of variable bioenergetic profile.

Journal: Mitochondrion 20120101

Title: Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injury.

Journal: Shock (Augusta, Ga.) 20120101

Title: Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle.

Journal: American journal of physiology. Cell physiology 20120101

Title: Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells.

Journal: International journal of molecular medicine 20120101

Title: Microarray expression analysis in delayed cardioprotection: the effect of exercise, AICAR, or metformin and the possible role of AMP-activated protein kinase (AMPK).

Journal: Molecular and cellular biochemistry 20120101

Title: AMP-activated protein kinase mediates effects of oxidative stress on embryo gene expression in a mouse model of diabetic embryopathy.

Journal: Diabetologia 20120101

Title: Adiponectin self-regulates its expression and multimerization in adipose tissue: an autocrine/paracrine mechanism?

Journal: Medical hypotheses 20120101

Title: AMP-activated protein kinase and the control of smooth muscle cell hyperproliferation in vascular disease.

Journal: Vascular pharmacology 20120101

Title: 3,5-Disubstituted-thiazolidine-2,4-dione analogs as anticancer agents: design, synthesis and biological characterization.

Journal: European journal of medicinal chemistry 20120101

Title: Short-term effects of combined iprodione and vermicompost applications on soil microbial community structure.

Journal: The Science of the total environment 20120101

Title: Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS).

Journal: Analytical and bioanalytical chemistry 20120101

Title: Anticancer properties of pomolic acid-induced AMP-activated protein kinase activation in MCF7 human breast cancer cells.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis.

Journal: PloS one 20120101

Title: HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

Journal: PLoS pathogens 20120101

Title: Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells.

Journal: PloS one 20120101

Title: Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production.

Journal: PloS one 20120101

Title: Intracerebroventricular administration of metformin inhibits ghrelin-induced Hypothalamic AMP-kinase signalling and food intake.

Journal: Neuroendocrinology 20120101

Title: Glucose enhances leptin signaling through modulation of AMPK activity.

Journal: PloS one 20120101

Title: Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice.

Journal: PloS one 20120101

Title: 5'-AMP Activated Protein Kinase is Involved in the Regulation of Myocardial β-Oxidative Capacity in Mice.

Journal: Frontiers in physiology 20120101

Title: Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Regular Multivitamin Supplement Use, Single Nucleotide Polymorphisms in ATIC, SHMT2, and SLC46A1, and Risk of Ovarian Carcinoma.

Journal: Frontiers in genetics 20120101

Title: Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes.

Journal: International journal of Alzheimer's disease 20120101

Title: Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes.

Journal: PloS one 20120101

Title: ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma.

Journal: Frontiers in oncology 20120101

Title: Alternative strategy for Alzheimer's disease: stress response triggers.

Journal: International journal of Alzheimer's disease 20120101

Title: Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.

Journal: PloS one 20120101

Title: Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes.

Journal: Journal of nutrition and metabolism 20120101

Title: MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor.

Journal: PloS one 20120101

Title: Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells.

Journal: The Journal of toxicological sciences 20120101

Title: Functional and structural comparison of pyrrolnitrin- and iprodione-induced modifications in the class III histidine-kinase Bos1 of Botrytis cinerea.

Journal: PloS one 20120101

Title: A low thermal mass fast gas chromatograph and its implementation in fast gas chromatography mass spectrometry with supersonic molecular beams.

Journal: Journal of chromatography. A 20111230

Title: 5'-AMP-activated protein kinase (AMPK) regulates progesterone receptor transcriptional activity in breast cancer cells.

Journal: Biochemical and biophysical research communications 20111209

Title: Antileukemic effects of AMPK activators on BCR-ABL-expressing cells.

Journal: Blood 20111208

Title: Stimulation of cardiomyogenesis of embryonic stem cells by nitric oxide downstream of AMP-activated protein kinase and mTOR signaling pathways.

Journal: Stem cells and development 20111201

Title: Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20111201

Title: 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent.

Journal: The Journal of pharmacology and experimental therapeutics 20111201

Title: Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology.

Journal: American journal of physiology. Cell physiology 20111201

Title: AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20111201

Title: 5-aminoimidazole-4-carboxamide riboside enhances effect of ionizing radiation in PC3 prostate cancer cells.

Journal: International journal of radiation oncology, biology, physics 20111201

Title: A novel cardioprotective agent in cardiac transplantation: metformin activation of AMP-activated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection.

Journal: The Yale journal of biology and medicine 20111201

Title: AICAR, a small chemical molecule, primes osteogenic differentiation of adult mesenchymal stem cells.

Journal: The International journal of artificial organs 20111201

Title: Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide.

Journal: The Journal of biological chemistry 20111125

Title: Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation.

Journal: Investigative ophthalmology & visual science 20111125

Title: Adiponectin promotes hyaluronan synthesis along with increases in hyaluronan synthase 2 transcripts through an AMP-activated protein kinase/peroxisome proliferator-activated receptor-α-dependent pathway in human dermal fibroblasts.

Journal: Biochemical and biophysical research communications 20111118

Title: AICAR reverses ketone body mediated insulin resistance in isolated oxidative muscle.

Journal: Biochemical and biophysical research communications 20111104

Title: Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries.

Journal: Clinical science (London, England : 1979) 20111101

Title: Role of the energy sensor adenosine monophosphate-activated protein kinase in the regulation of immature gonadotropin-releasing hormone neuron migration.

Journal: Journal of endocrinological investigation 20111101

Title: Inhibition of hepatitis C virus replication through adenosine monophosphate-activated protein kinase-dependent and -independent pathways.

Journal: Microbiology and immunology 20111101

Title: Central AMP-activated protein kinase affects sympathetic nerve activity in rats.

Journal: Neuroscience letters 20111010

Title: Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle.

Journal: The Journal of biological chemistry 20111007

Title: Intravenous AICAR during hyperinsulinemia induces systemic hemodynamic changes but has no local metabolic effect.

Journal: Journal of clinical pharmacology 20111001

Title: AMP-activated protein kinase plays a role in initiating metabolic rate suppression in goldfish hepatocytes.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20111001

Title: Activated AMPK inhibits PPAR-{alpha} and PPAR-{gamma} transcriptional activity in hepatoma cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20111001

Title: The influence of the BRAF V600E mutation in thyroid cancer cell lines on the anticancer effects of 5-aminoimidazole-4-carboxamide-ribonucleoside.

Journal: The Journal of endocrinology 20111001

Title: Defective myofibroblast formation from mesenchymal stem cells in the aging murine heart rescue by activation of the AMPK pathway.

Journal: The American journal of pathology 20111001

Title: Angiotensin II upregulates protein phosphatase 2Cα and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting.

Journal: Hypertension (Dallas, Tex. : 1979) 20111001

Title: Transcriptome-wide binding sites for components of the Saccharomyces cerevisiae non-poly(A) termination pathway: Nrd1, Nab3, and Sen1.

Journal: PLoS genetics 20111001

Title: Activation of the metabolic sensor-AMP activated protein kinase reverses impairment of angiogenesis in aging myocardial microvascular endothelial cells. Implications for the aging heart.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20111001

Title: Solid-phase synthesis of a new diphosphate 5-aminoimidazole-4-carboxamide riboside (AICAR) derivative and studies toward cyclic AICAR diphosphate ribose.

Journal: Molecules (Basel, Switzerland) 20110921

Title: Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.

Journal: Talanta 20110915

Title: Physiological and toxic effects of purine intermediate 5-amino-4-imidazolecarboxamide ribonucleotide (AICAR) in yeast.

Journal: The Journal of biological chemistry 20110902

Title: AMP-activated protein kinase regulates normal rat somatotroph cell function and growth of rat pituitary adenomatous cells.

Journal: Pituitary 20110901

Title: Dynamic alteration of adiponectin/adiponectin receptor expression and its impact on myocardial ischemia/reperfusion in type 1 diabetic mice.

Journal: American journal of physiology. Endocrinology and metabolism 20110901

Title: Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle.

Journal: Human molecular genetics 20110901

Title: purL gene expression affects biofilm formation and symbiotic persistence of Photorhabdus temperata in the nematode Heterorhabditis bacteriophora.

Journal: Microbiology (Reading, England) 20110901

Title: Reductions in RIP140 are not required for exercise- and AICAR-mediated increases in skeletal muscle mitochondrial content.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20110901

Title: Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity.

Journal: Journal of lipid research 20110901

Title: Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats.

Journal: Investigative ophthalmology & visual science 20110822

Title: Structure-activity relationship studies of novel pyrazole and imidazole carboxamides as cannabinoid-1 (CB1) antagonists.

Journal: Bioorganic & medicinal chemistry letters 20110815

Title: Antagonistic control of muscle cell size by AMPK and mTORC1.

Journal: Cell cycle (Georgetown, Tex.) 20110815

Title: Deficiency of insulin-like growth factor 1 reduces vulnerability to chronic alcohol intake-induced cardiomyocyte mechanical dysfunction: role of AMPK.

Journal: Journal of cellular and molecular medicine 20110801

Title: Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.

Journal: Annals of the rheumatic diseases 20110801

Title: AICAR and Compound C regulate food intake independently of AMP-activated protein kinase in lines of chickens selected for high or low body weight.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110801

Title: Mice lacking TR4 nuclear receptor develop mitochondrial myopathy with deficiency in complex I.

Journal: Molecular endocrinology (Baltimore, Md.) 20110801

Title: Acute therapeutic use of 5-aminoimidazole-4-carboxamide ribonucleoside extends survival interval in response to severe hemorrhagic shock.

Journal: Shock (Augusta, Ga.) 20110801

Title: Globular adiponectin protects human umbilical vein endothelial cells against apoptosis through adiponectin receptor 1/adenosine monophosphate-activated protein kinase pathway.

Journal: Chinese medical journal 20110801

Title: Chalkbrood transmission in the alfalfa leafcutting bee: the impact of disinfecting bee cocoons in loose cell management systems.

Journal: Environmental entomology 20110801

Title: AMP-activated protein kinase activates neuropeptide Y neurons in the hypothalamic arcuate nucleus to increase food intake in rats.

Journal: Neuroscience letters 20110725

Title: In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis.

Journal: Cell metabolism 20110706

Title: Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors.

Journal: Cancer chemotherapy and pharmacology 20110701

Title: Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20110701

Title: Down-regulation of the ubiquitin-proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes.

Journal: Amino acids 20110701

Title: Functional analysis of the 5' flanking region of the human G6PC3 gene: regulation of promoter activity by glucose, pyruvate, AMP kinase and the pentose phosphate pathway.

Journal: Molecular genetics and metabolism 20110701

Title: AICAR, an activator of AMPK, inhibits adipogenesis via the WNT/β-catenin pathway in 3T3-L1 adipocytes.

Journal: International journal of molecular medicine 20110701

Title: Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell.

Journal: Journal of cellular physiology 20110701

Title: AMPK activation enhances PPARα activity to inhibit cardiac hypertrophy via ERK1/2 MAPK signaling pathway.

Journal: Archives of biochemistry and biophysics 20110701

Title: Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110701

Title: LKB1/AMPK/mTOR signaling pathway in hematological malignancies: from metabolism to cancer cell biology.

Journal: Cell cycle (Georgetown, Tex.) 20110701

Title: Chronic high cytosolic calcium decreases AICAR-induced AMPK activity via calcium/calmodulin activated protein kinase II signaling cascade.

Journal: Cell calcium 20110701

Title: Na,K-ATPase activity in mouse muscle is regulated by AMPK and PGC-1α.

Journal: The Journal of membrane biology 20110701

Title: Involvement of a phosphorylation-mediated pathway to regulate the function of NSPL1 in exercise.

Journal: The Journal of veterinary medical science 20110601

Title: A novel role for AMP-kinase in the regulation of the Na+/I--symporter and iodide uptake in the rat thyroid gland.

Journal: American journal of physiology. Cell physiology 20110601

Title: AMP-activated protein kinase rescues the angiogenic functions of endothelial progenitor cells via manganese superoxide dismutase induction in type 1 diabetes.

Journal: American journal of physiology. Endocrinology and metabolism 20110601

Title: α₂-Adrenoceptors activate noradrenaline-mediated glycogen turnover in chick astrocytes.

Journal: Journal of neurochemistry 20110601

Title: Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling.

Journal: The Journal of clinical investigation 20110601

Title: AICAR inhibits cancer cell growth and triggers cell-type distinct effects on OXPHOS biogenesis, oxidative stress and Akt activation.

Journal: Biochimica et biophysica acta 20110601

Title: Beneficial effects of metformin on primary cardiomyocytes via activation of adenosine monophosphate-activated protein kinase.

Journal: Chinese medical journal 20110601

Title: AICAR induced AMPK activation potentiates neuronal insulin signaling and glucose uptake.

Journal: Archives of biochemistry and biophysics 20110515

Title: Activation of AMP-activated protein kinase may not be involved in AICAR- and metformin-mediated meiotic arrest in bovine denuded and cumulus-enclosed oocytes in vitro.

Journal: Zygote (Cambridge, England) 20110501

Title: Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study.

Journal: Cancer chemotherapy and pharmacology 20110501

Title: Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

Journal: Molecular and biochemical parasitology 20110501

Title: Evidence that chromium modulates cellular cholesterol homeostasis and ABCA1 functionality impaired by hyperinsulinemia--brief report.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110501

Title: AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20110501

Title: Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction.

Journal: Clinical and experimental pharmacology & physiology 20110501

Title: Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.

Journal: Molecular endocrinology (Baltimore, Md.) 20110501

Title: Arecoline-mediated inhibition of AMP-activated protein kinase through reactive oxygen species is required for apoptosis induction.

Journal: Oral oncology 20110501

Title: Inhibition of the AMP-activated protein kinase-α2 accentuates agonist-induced vascular smooth muscle contraction and high blood pressure in mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20110501

Title: Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.

Journal: Nature immunology 20110501

Title: Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet.

Journal: Drug testing and analysis 20110501

Title: LITAF and TNFSF15, two downstream targets of AMPK, exert inhibitory effects on tumor growth.

Journal: Oncogene 20110421

Title: Diminished AMPK signaling response to fasting in thioredoxin-interacting protein knockout mice.

Journal: FEBS letters 20110420

Title: AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization.

Journal: Science (New York, N.Y.) 20110408

Title: Metformin induces Rab4 through AMPK and modulates GLUT4 translocation in skeletal muscle cells.

Journal: Journal of cellular physiology 20110401

Title: Effect of LKB1 deficiency on mitochondrial content, fibre type and muscle performance in the mouse diaphragm.

Journal: Acta physiologica (Oxford, England) 20110401

Title: Abnormal metabolism flexibility in response to high palmitate concentrations in myotubes derived from obese type 2 diabetic patients.

Journal: Biochimica et biophysica acta 20110401

Title: Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20110401

Title: Isoform-selective 5'-AMP-activated protein kinase-dependent preconditioning mechanisms to prevent postischemic leukocyte-endothelial cell adhesive interactions.

Journal: American journal of physiology. Heart and circulatory physiology 20110401

Title: Involvement of oxygen-regulated protein 150 in AMP-activated protein kinase-mediated alleviation of lipid-induced endoplasmic reticulum stress.

Journal: The Journal of biological chemistry 20110401

Title: Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake is AMPK independent.

Journal: Journal of lipid research 20110401

Title: Activation of AMP-kinase by policosanol requires peroxisomal metabolism.

Journal: Lipids 20110401

Title: One-pot synthesis of 2-amino-indole-3-carboxamide and analogous.

Journal: ACS combinatorial science 20110314

Title: Leptin controls ketone body utilization in hypothalamic neuron.

Journal: Neuroscience letters 20110303

Title: Metabolic stress modulates motor patterning via AMP-activated protein kinase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110302

Title: Short-term adenosine monophosphate-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle.

Journal: Metabolism: clinical and experimental 20110301

Title: In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes.

Journal: Biochemistry 20110301

Title: AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia.

Journal: Molecular cancer therapeutics 20110301

Title: Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways.

Journal: Diabetes 20110301

Title: Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle.

Journal: Diabetes 20110301

Title: Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians.

Journal: The Indian journal of medical research 20110301

Title: Identification of aneuploidy-selective antiproliferation compounds.

Journal: Cell 20110218

Title: Metabolic stress boosts humoral responses in vivo independently of inflammasome and inflammatory reaction.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20110215

Title: Activation of adenosine-monophosphate-activated protein kinase abolishes desflurane-induced preconditioning against myocardial infarction in vivo.

Journal: Journal of cardiothoracic and vascular anesthesia 20110201

Title: Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.

Journal: Journal of inherited metabolic disease 20110201

Title: Effect of exercise intensity and AICAR on isoform-specific expressions of murine skeletal muscle PGC-1α mRNA: a role of β₂-adrenergic receptor activation.

Journal: American journal of physiology. Endocrinology and metabolism 20110201

Title: Plasticity in the purine-thiamine metabolic network of Salmonella.

Journal: Genetics 20110201

Title: Metformin improves cardiac function in rats via activation of AMP-activated protein kinase.

Journal: Clinical and experimental pharmacology & physiology 20110201

Title: Central infusion of leptin does not increase AMPK signaling in skeletal muscle of sheep.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110201

Title: Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase.

Journal: Molecular membrane biology 20110201

Title: Endurance factors improve hippocampal neurogenesis and spatial memory in mice.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20110201

Title: AMP-activated protein kinase inhibits homocysteine-induced dysfunction and apoptosis in endothelial progenitor cells.

Journal: Cardiovascular drugs and therapy 20110201

Title: The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function.

Journal: Diabetes 20110201

Title: Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding.

Journal: Diabetes 20110201

Title: Sensitivity of Penicillium expansum field isolates to tebuconazole, iprodione, fludioxonil and cyprodinil and characterization of fitness parameters and patulin production.

Journal: International journal of food microbiology 20110131

Title: AMP-activated protein kinase (AMPK) positively regulates osteoblast differentiation via induction of Dlx5-dependent Runx2 expression in MC3T3E1 cells.

Journal: Biochemical and biophysical research communications 20110128

Title: AMP-activated protein kinase regulates the expression of monocarboxylate transporter 4 in skeletal muscle.

Journal: Life sciences 20110117

Title: Does long-term metformin treatment increase cardiac lipoprotein lipase?

Journal: Metabolism: clinical and experimental 20110101

Title: Enhancement of extracellular purine nucleoside accumulation by Bacillus strains through genetic modifications of genes involved in nucleoside export.

Journal: Journal of industrial microbiology & biotechnology 20110101

Title: Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice.

Journal: Cardiovascular research 20110101

Title: Endothelium-dependent vasorelaxation to the AMPK activator AICAR is enhanced in aorta from hypertensive rats and is NO and EDCF dependent.

Journal: American journal of physiology. Heart and circulatory physiology 20110101

Title: Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival.

Journal: American journal of physiology. Heart and circulatory physiology 20110101

Title: Potential role of adenosine monophosphate-activated protein kinase in regulation of energy metabolism in dairy goat mammary epithelial cells.

Journal: Journal of dairy science 20110101

Title: Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-kappaB-dependent pathway.

Journal: Arthritis research & therapy 20110101

Title: Adenosine activates AMPK to phosphorylate Bcl-XL responsible for mitochondrial damage and DIABLO release in HuH-7 cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

Title: Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate.

Journal: Arthritis research & therapy 20110101

Title: An invertebrate hyperglycemic model for the identification of anti-diabetic drugs.

Journal: PloS one 20110101

Title: Oral inflammatory myofibroblastic tumor: case report and review of literature.

Journal: The open dentistry journal 20110101

Title: Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder.

Journal: BMC medical genetics 20110101

Title: Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription.

Journal: International journal of biological sciences 20110101

Title: Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation.

Journal: PloS one 20110101

Title: Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling.

Journal: BMC systems biology 20110101

Title: The effect of an intracerebroventricular injection of metformin or AICAR on the plasma concentrations of melatonin in the ewe: potential involvement of AMPK?

Journal: BMC neuroscience 20110101

Title: Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic Goto-Kakizaki rats.

Journal: PloS one 20110101

Title: Intracellular trafficking as a determinant of AS-DACA cytotoxicity in rhabdomyosarcoma cells.

Journal: BMC cell biology 20110101

Title: Upstream molecular signaling pathways of p27(Kip1) expression in human breast cancer cells in vitro: differential effects of 4-hydroxytamoxifen and deficiency of either D-(+)-glucose or L-leucine.

Journal: Cancer cell international 20110101

Title: Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain.

Journal: Molecular pain 20110101

Title: The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases.

Journal: Mechanisms of ageing and development 20110101

Title: Screening for active small molecules in mitochondrial complex I deficient patient's fibroblasts, reveals AICAR as the most beneficial compound.

Journal: PloS one 20110101

Title: Metabolic specialization of mouse embryonic stem cells.

Journal: Cold Spring Harbor symposia on quantitative biology 20110101

Title: Biological monitoring of pesticide exposures in residents living near agricultural land.

Journal: BMC public health 20110101

Title: Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study.

Journal: BMC medical genetics 20110101

Title: Increased FAT/CD36 cycling and lipid accumulation in myotubes derived from obese type 2 diabetic patients.

Journal: PloS one 20110101

Title: Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications.

Journal: Acta naturae 20110101

Title: Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition.

Journal: Oncogene 20101216

Title: Adenosine regulates Sertoli cell function by activating AMPK.

Journal: Molecular and cellular endocrinology 20101215

Title: Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas.

Journal: Cancer research 20101215

Title: AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis.

Journal: Biochemical pharmacology 20101201

Title: Genetic downregulation of AMPK-alpha isoforms uncovers the mechanism by which metformin decreases FA uptake and oxidation in skeletal muscle cells.

Journal: American journal of physiology. Cell physiology 20101201

Title: AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20101201

Title: AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells.

Journal: American journal of physiology. Renal physiology 20101201

Title: AMPK as a therapeutic target in renal cell carcinoma.

Journal: Cancer biology & therapy 20101201

Title: AMPK signaling: a targetable tumor suppressor pathway?

Journal: Cancer biology & therapy 20101201

Title: Chemoselective multicomponent one-pot assembly of purine precursors in water.

Journal: Journal of the American Chemical Society 20101124

Title: AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF.

Journal: The Journal of biological chemistry 20101112

Title: ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells.

Journal: Biochemical and biophysical research communications 20101112

Title: AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3).

Journal: Diabetologia 20101101

Title: Combined in silico and experimental approach for drug design: the binding mode of peptidic and non-peptidic inhibitors to hsp90 N-terminal domain.

Journal: Chemical biology & drug design 20101101

Title: [Effects of AMPK on the transcriptional activity of FOXO1 and ubiquitin ligase MuRF1 expression in rat cardiomyocytes].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20101101

Title: Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia.

Journal: Cell death & disease 20101101

Title: Adenosine monophosphate-activated protein kinase induces cholesterol efflux from macrophage-derived foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice.

Journal: The Journal of biological chemistry 20101022

Title: AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.

Journal: Blood 20101021

Title: AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-beta-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway.

Journal: Biochemical pharmacology 20101015

Title: Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.

Journal: The Biochemical journal 20101015

Title: 5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB.

Journal: Immunology and cell biology 20101001

Title: Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumors.

Journal: Molecular pharmacology 20101001

Title: Melanocortin-4 receptor activation promotes insulin-stimulated mTOR signaling.

Journal: Peptides 20101001

Title: Hypothalamic AMP-activated protein kinase regulates glucose production.

Journal: Diabetes 20101001

Title: Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle.

Journal: Diabetes 20101001

Title: Role of AMPK throughout meiotic maturation in the mouse oocyte: evidence for promotion of polar body formation and suppression of premature activation.

Journal: Molecular reproduction and development 20101001

Title: Plant-growth regulator, imidazole-4-carboxamide, produced by the fairy ring forming fungus Lepista sordida.

Journal: Journal of agricultural and food chemistry 20100922

Title: Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.

Journal: Bioorganic & medicinal chemistry 20100915

Title: Studies on ligand binding to histidine triad nucleotide binding protein 1.

Journal: Bioorganic & medicinal chemistry 20100915

Title: AMP-activated protein kinase controls metabolism and heat production during embryonic development in birds.

Journal: The Journal of experimental biology 20100915

Title: Coordinated maintenance of muscle cell size control by AMP-activated protein kinase.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100901

Title: {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20100901

Title: The mitogen-activated protein kinase kinase BOS5 is involved in regulating vegetative differentiation and virulence in Botrytis cinerea.

Journal: Fungal genetics and biology : FG & B 20100901

Title: PGC-1{alpha} is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20100901

Title: AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38 MAPK.

Journal: Molecular endocrinology (Baltimore, Md.) 20100901

Title: Rosiglitazone inhibits monocyte/macrophage adhesion through de novo adiponectin production in human monocytes.

Journal: Journal of cellular biochemistry 20100815

Title: AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear respiratory factor 1 expression in rat visual cortical neurons.

Journal: Neuroscience 20100811

Title: Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100801

Title: AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass.

Journal: Bone 20100801

Title: A pharmacological activator of AMP-activated protein kinase protects hypoxic neurons in a concentration-dependent manner.

Journal: Neurochemical research 20100801

Title: Metabolic preconditioning of cells with AICAR-riboside: improved cryopreservation and cell-type specific impacts on energetics and proliferation.

Journal: Cryobiology 20100801

Title: Chronic AMP-activated protein kinase activation and a high-fat diet have an additive effect on mitochondria in rat skeletal muscle.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100801

Title: AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARalpha, but not PPARgamma, in rat insulinoma cell line INS-1.

Journal: Acta pharmacologica Sinica 20100801

Title: 5-aminoimidazole-4-carboxamide-1-beta-ribofuranoside (AICAR) prevents nuclear translocation of constitutive androstane receptor by AMP-activated protein kinase (AMPK) independent manner.

Journal: The Journal of toxicological sciences 20100801

Title: siRNA-mediated AMPKalpha1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells.

Journal: The Journal of toxicological sciences 20100801

Title: AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival.

Journal: Biochemical and biophysical research communications 20100716

Title: Adenosine monophosphate activated protein kinase regulates ABCG1-mediated oxysterol efflux from endothelial cells and protects against hypercholesterolemia-induced endothelial dysfunction.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100701

Title: The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100701

Title: Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells.

Journal: American journal of physiology. Renal physiology 20100701

Title: Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro.

Journal: Acta pharmacologica Sinica 20100701

Title: Analysis and stability study of temozolomide using capillary electrophoresis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100701

Title: Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy.

Journal: The Journal of biological chemistry 20100618

Title: To eat or not to eat: the effect of AICAR on food intake regulation in yellow-bellied marmots (Marmota flaviventris).

Journal: The Journal of experimental biology 20100615

Title: AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells.

Journal: Biochemical and biophysical research communications 20100604

Title: AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.

Journal: American journal of respiratory cell and molecular biology 20100601

Title: In vivo proton MR spectroscopy findings specific for adenylosuccinate lyase deficiency.

Journal: NMR in biomedicine 20100601

Title: Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100601

Title: Novel anti-inflammatory action of 5-aminoimidazole-4-carboxamide ribonucleoside with protective effect in dextran sulfate sodium-induced acute and chronic colitis.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: Stimulators of AMP-activated kinase (AMPK) inhibit seawater- but not cAMP-induced oocyte maturation in a marine worm: Implications for interactions between cAMP and AMPK signaling.

Journal: Molecular reproduction and development 20100601

Title: In vivo stimulation of AMP-activated protein kinase enhanced tubuloglomerular feedback but reduced tubular sodium transport during high dietary NaCl intake.

Journal: Pflugers Archiv : European journal of physiology 20100601

Title: Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100601

Title: Anti-growth effect of 1,25-dihydroxyvitamin D3-3-bromoacetate alone or in combination with 5-amino-imidazole-4-carboxamide-1-beta-4-ribofuranoside in pancreatic cancer cells.

Journal: Anticancer research 20100601

Title: Acadesine inhibits tissue factor induction and thrombus formation by activating the phosphoinositide 3-kinase/Akt signaling pathway.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100501

Title: Differential AMPK phosphorylation sites associated with phenylephrine vs. antihypertrophic effects of adenosine agonists in neonatal rat ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20100501

Title: Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts.

Journal: Experimental & molecular medicine 20100430

Title: AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes.

Journal: Circulation research 20100402

Title: Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase.

Journal: Diabetologia 20100401

Title: Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.

Journal: Diabetes 20100401

Title: Quantification of urinary AICAR concentrations as a matter of doping controls.

Journal: Analytical and bioanalytical chemistry 20100401

Title: AICA-riboside (acadesine), an activator of AMP-activated protein kinase with potential for application in hematologic malignancies.

Journal: Expert opinion on investigational drugs 20100401

Title: GTPase activity plays a key role in the pathobiology of LRRK2.

Journal: PLoS genetics 20100401

Title: Short-term AMP-regulated protein kinase activation enhances insulin-sensitive fatty acid uptake and increases the effects of insulin on fatty acid oxidation in L6 muscle cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100401

Title: A microarray-based genetic screen for yeast chronological aging factors.

Journal: PLoS genetics 20100401

Title: Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium.

Journal: Experimental & molecular medicine 20100331

Title: Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

Journal: Oncogene 20100318

Title: Non-CDK-bound p27 (p27(NCDK)) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways.

Journal: Experimental cell research 20100310

Title: Central role of nitric oxide synthase in AICAR and caffeine-induced mitochondrial biogenesis in L6 myocytes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100301

Title: Adenosine 5'-monophosphate-activated protein kinase-mammalian target of rapamycin cross talk regulates brown adipocyte differentiation.

Journal: Endocrinology 20100301

Title: Cardioprotection with adenosine-regulating agent, GP531: effects on no-reflow, infarct size, and blood flow following ischemia/ reperfusion in the rabbit.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100301

Title: Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes.

Journal: Acta pharmacologica Sinica 20100301

Title: Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

Journal: The Biochemical journal 20100215

Title: Quantification of iprodione in dry basil using silica gel supported titanium dioxide.

Journal: Journal of agricultural and food chemistry 20100210

Title: Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase .

Journal: Biochemistry 20100202

Title: Acute exposure to rosiglitazone does not affect glucose transport in intact human skeletal muscle.

Journal: Metabolism: clinical and experimental 20100201

Title: Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.

Journal: Free radical research 20100201

Title: AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

Journal: American journal of physiology. Endocrinology and metabolism 20100201

Title: Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle.

Journal: American journal of physiology. Cell physiology 20100201

Title: Metformin increases phagocytosis and acidifies lysosomal/endosomal compartments in AMPK-dependent manner in rat primary microglia.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100201

Title: Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction.

Journal: Cardiovascular drugs and therapy 20100201

Title: Germline deletion of AMP-activated protein kinase beta subunits reduces bone mass without altering osteoclast differentiation or function.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100101

Title: Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells.

Journal: Diabetes 20100101

Title: AICAR (5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside) increases the production of toxic molecules and affects the profile of cytokines release in LPS-stimulated rat primary microglial cultures.

Journal: Neurotoxicology 20100101

Title: Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells.

Journal: Journal of endocrinological investigation 20100101

Title: Ethanol inhibits gastric acid secretion in rats through increased AMP-kinase activity.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: Metabolic regulation of neuronal plasticity by the energy sensor AMPK.

Journal: PloS one 20100101

Title: AMPK exerts dual regulatory effects on the PI3K pathway.

Journal: Journal of molecular signaling 20100101

Title: Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids.

Journal: Cancer cell international 20100101

Title: Phospholipase D1 mediates AMP-activated protein kinase signaling for glucose uptake.

Journal: PloS one 20100101

Title: PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia.

Journal: PloS one 20100101

Title: 5-ALA mediated photodynamic therapy induces autophagic cell death via AMP-activated protein kinase.

Journal: Molecular cancer 20100101

Title: PRAS40 regulates protein synthesis and cell cycle in C2C12 myoblasts.

Journal: Molecular medicine (Cambridge, Mass.) 20100101

Title: Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner.

Journal: PloS one 20100101

Title: Oligodendroglia from ADSL-deficient patient produce SAICAribotide and SAMP.

Journal: Molecular genetics and metabolism 20100101

Title: AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia.

Journal: Journal of molecular signaling 20100101

Title: MOLA: a bootable, self-configuring system for virtual screening using AutoDock4/Vina on computer clusters.

Journal: Journal of cheminformatics 20100101

Title: Microsatellite stability in the plant pathogen Botrytis cinerea after exposure to different selective pressures.

Journal: Fungal biology 20100101

Title: Dockomatic - automated ligand creation and docking.

Journal: BMC research notes 20100101

Title: Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures.

Journal: Pharmacological reports : PR 20100101

Title: Activation of the AMP-activated protein kinase enhances glucose-stimulated insulin secretion in mouse β-cells.

Journal: Islets 20100101

Title: AMP-activated protein kinase activation during cardioplegia-induced hypoxia/reoxygenation injury attenuates cardiomyocytic apoptosis via reduction of endoplasmic reticulum stress.

Journal: Mediators of inflammation 20100101

Title: Pathobiology of anaplastic large cell lymphoma.

Journal: Advances in hematology 20100101

Title: Activation of AMP-activated protein kinase (AMPK) inhibits fatty acid synthesis in bovine mammary epithelial cells.

Journal: Biochemical and biophysical research communications 20091218

Title: Development of hepatic fibrosis occurs normally in AMPK-deficient mice.

Journal: Clinical science (London, England : 1979) 20091214

Title: Activation of AMP-activated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation.

Journal: The Journal of biological chemistry 20091211

Title: Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.

Journal: Atherosclerosis 20091201

Title: The 5' adenosine monophosphate-activated protein kinase: regulating the ebb and flow of cellular energetics.

Journal: The international journal of biochemistry & cell biology 20091201

Title: Glucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cells.

Journal: Diabetes 20091201

Title: Osteoblast differentiation is functionally associated with decreased AMP kinase activity.

Journal: Journal of cellular physiology 20091201

Title: CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20091201

Title: Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytes.

Journal: FEBS letters 20091119

Title: Anergic T cells are metabolically anergic.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115

Title: Glucose, metformin, and AICAR regulate the expression of G protein-coupled receptor members in INS-1 beta cell.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091101

Title: Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity.

Journal: Diabetologia 20091101

Title: Restoring AS160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids.

Journal: American journal of physiology. Endocrinology and metabolism 20091101

Title: Basal autophagy induction without AMP-activated protein kinase under low glucose conditions.

Journal: Autophagy 20091101

Title: Toxicity of fungicides with different modes of action to Cladobotryum dendroides and Agaricus bisporus.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20091101

Title: AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.

Journal: Science (New York, N.Y.) 20091016

Title: Police find range of drugs after trawling bins used by Tour de France cyclists.

Journal: BMJ (Clinical research ed.) 20091013

Title: C1q tumor necrosis factor alpha-related protein isoform 5 is increased in mitochondrial DNA-depleted myocytes and activates AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20091009

Title: Metformin promotes induction of lipoprotein lipase in skeletal muscle through activation of adenosine monophosphate-activated protein kinase.

Journal: Metabolism: clinical and experimental 20091001

Title: Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin.

Journal: Diabetes 20091001

Title: Chronic activation of 5'-AMP-activated protein kinase changes myosin heavy chain expression in growing pigs.

Journal: Journal of animal science 20091001

Title: AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes.

Journal: Journal of cellular biochemistry 20091001

Title: Genetic impairment of AMPKalpha2 signaling does not reduce muscle glucose uptake during treadmill exercise in mice.

Journal: American journal of physiology. Endocrinology and metabolism 20091001

Title: The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP.

Journal: Molecular and cellular biochemistry 20090901

Title: Fatty acid oxidation and meiotic resumption in mouse oocytes.

Journal: Molecular reproduction and development 20090901

Title: Cumulative and antagonistic effects of a mixture of the antiandrogens vinclozolin and iprodione in the pubertal male rat.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090901

Title: AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons.

Journal: American journal of physiology. Cell physiology 20090901

Title: Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside.

Journal: The Journal of endocrinology 20090901

Title: Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20090901

Title: Central AMPK contributes to sleep homeostasis in mice.

Journal: Neuropharmacology 20090901

Title: The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20090901

Title: Analysis of pesticide residues by fast gas chromatography in combination with negative chemical ionization mass spectrometry.

Journal: Journal of chromatography. A 20090828

Title: Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes.

Journal: Clinical science (London, England : 1979) 20090814

Title: The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090804

Title: Adiponectin downregulates CD163 whose cellular and soluble forms are elevated in obesity.

Journal: European journal of clinical investigation 20090801

Title: AMPK inhibits myoblast differentiation through a PGC-1alpha-dependent mechanism.

Journal: American journal of physiology. Endocrinology and metabolism 20090801

Title: Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20090801

Title: Green tea catechin controls apoptosis in colon cancer cells by attenuation of H2O2-stimulated COX-2 expression via the AMPK signaling pathway at low-dose H2O2.

Journal: Annals of the New York Academy of Sciences 20090801

Title: Effects of cotreatment of 12-O-tetradecanoylphorbol-13-acetate and H2O2 on apoptotic regulation via AMP-activated protein kinase-cyclooxygenase-2 signals.

Journal: Annals of the New York Academy of Sciences 20090801

Title: Application of prolonged microdialysis sampling in carboplatin-treated cancer patients.

Journal: Cancer chemotherapy and pharmacology 20090701

Title: Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation.

Journal: Obesity (Silver Spring, Md.) 20090701

Title: PGC-1alpha mediates exercise-induced skeletal muscle VEGF expression in mice.

Journal: American journal of physiology. Endocrinology and metabolism 20090701

Title: Regulation and function of proline oxidase under nutrient stress.

Journal: Journal of cellular biochemistry 20090701

Title: Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation.

Journal: American journal of physiology. Endocrinology and metabolism 20090701

Title: Effects of AMPK activators on the sub-cellular distribution of fatty acid transporters CD36 and FABPpm.

Journal: Archives of physiology and biochemistry 20090701

Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: potential role of AMP-activated protein kinase.

Journal: Basic & clinical pharmacology & toxicology 20090701

Title: Adiponectin decreases pyruvate dehydrogenase kinase 4 gene expression in obese- and diabetic-derived myotubes.

Journal: Diabetes, obesity & metabolism 20090701

Title: Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition.

Journal: Cancer research 20090701

Title: Toward synthesis of the isosteric sulfonate analogues of the AT-III binding domain of heparin.

Journal: Organic letters 20090618

Title: Anaplastic lymphoma kinase: signalling in development and disease.

Journal: The Biochemical journal 20090615

Title: Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways.

Journal: Genes & development 20090615

Title: Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR).

Journal: Cell biology and toxicology 20090601

Title: Contractions but not AICAR increase FABPpm content in rat muscle sarcolemma.

Journal: Molecular and cellular biochemistry 20090601

Title: Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction.

Journal: Journal of molecular and cellular cardiology 20090601

Title: Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090601

Title: Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the K(ATP) channel and insulin secretion in rats.

Journal: Diabetologia 20090601

Title: AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C.

Journal: Biochemical pharmacology 20090601

Title: Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells.

Journal: Clinical and experimental immunology 20090601

Title: Leptin inhibits glycogen synthase kinase-3beta to prevent tau phosphorylation in neuronal cells.

Journal: Neuroscience letters 20090522

Title: Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.

Journal: Circulation 20090519

Title: Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry.

Journal: Journal of medicinal chemistry 20090514

Title: Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells.

Journal: Oncogene 20090507

Title: Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance.

Journal: Endocrinology 20090501

Title: Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.

Journal: Diabetes 20090501

Title: A myosin II ATPase inhibitor reduces force production, glucose transport, and phosphorylation of AMPK and TBC1D1 in electrically stimulated rat skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20090501

Title: Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status.

Journal: American journal of physiology. Endocrinology and metabolism 20090501

Title: Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose.

Journal: American journal of physiology. Endocrinology and metabolism 20090501

Title: AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

Journal: Acta physiologica (Oxford, England) 20090501

Title: AMP-activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle.

Journal: The Journal of physiology 20090501

Title: AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.

Journal: Nature 20090423

Title: The deacetylase enzyme SIRT1 is not associated with oxidative capacity in rat heart and skeletal muscle and its overexpression reduces mitochondrial biogenesis.

Journal: The Journal of physiology 20090415

Title: Regulation of erythrocyte survival by AMP-activated protein kinase.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090401

Title: Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL.

Journal: Journal of lipid research 20090401

Title: Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.

Journal: Biochimica et biophysica acta 20090401

Title: Resistin acutely impairs insulin-stimulated glucose transport in rodent muscle in the presence, but not absence, of palmitate.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090401

Title: AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.

Journal: American journal of physiology. Cell physiology 20090401

Title: AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease.

Journal: Clinical science (London, England : 1979) 20090401

Title: AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells.

Journal: Journal of cellular and molecular medicine 20090401

Title: [Genetic control of metabolism of mutagenic purine base analogs 6-hydroxylaminopurine and 2-amino-6-hydroxylaminopurine in yeast Saccharomyces cerevisiae].

Journal: Genetika 20090401

Title: The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.

Journal: Blood 20090319

Title: [Doping in the next generation: wringing extra performance from the genotype].

Journal: MMW Fortschritte der Medizin 20090319

Title: AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D.

Journal: The Journal of biological chemistry 20090306

Title: Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090304

Title: Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha.

Journal: American journal of respiratory cell and molecular biology 20090301

Title: Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090301

Title: Crucial role for LKB1 to AMPKalpha2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes.

Journal: Biochimica et biophysica acta 20090301

Title: Exercise: it's the real thing!

Journal: Nutrition reviews 20090301

Title: Adiponectin inhibits insulin-like growth factor-1-induced cell migration by the suppression of extracellular signal-regulated kinase 1/2 activation, but not Akt in vascular smooth muscle cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090301

Title: Mechanistic insight into control of CFTR by AMPK.

Journal: The Journal of biological chemistry 20090227

Title: AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633.

Journal: Circulation research 20090227

Title: Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells.

Journal: Biochemical and biophysical research communications 20090227

Title: Kinase activity-independent suppression of p73alpha by AMP-activated kinase alpha (AMPKalpha).

Journal: Oncogene 20090219

Title: Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.

Journal: Endocrinology 20090201

Title: Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.

Journal: The British journal of dermatology 20090201

Title: Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells.

Journal: American journal of physiology. Cell physiology 20090201

Title: AICAR preconditioning prevents postischemic leukocyte rolling and adhesion: role of K(ATP) channels and heme oxygenase.

Journal: Microcirculation (New York, N.Y. : 1994) 20090201

Title: A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090201

Title: 2-Deoxy-d-glucose protects neural progenitor cells against oxidative stress through the activation of AMP-activated protein kinase.

Journal: Neuroscience letters 20090116

Title: AMPK-sensed cellular energy state regulates the release of extracellular Fatty Acid Synthase.

Journal: Biochemical and biophysical research communications 20090116

Title: Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase.

Journal: Bioorganic & medicinal chemistry 20090115

Title: The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor.

Journal: Cell metabolism 20090107

Title: C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.

Journal: The Journal of biological chemistry 20090102

Title: Involvement of AMP-activated protein kinase and p38 mitogen-activated protein kinase in 8-Cl-cAMP-induced growth inhibition.

Journal: Journal of cellular physiology 20090101

Title: Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators.

Journal: IUBMB life 20090101

Title: Misleading behavioural phenotype with adenylosuccinate lyase deficiency.

Journal: European journal of human genetics : EJHG 20090101

Title: Alpha2-AMPK activity is not essential for an increase in fatty acid oxidation during low-intensity exercise.

Journal: American journal of physiology. Endocrinology and metabolism 20090101

Title: Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 myoblasts.

Journal: Endocrine journal 20090101

Title: Chronic elevated calcium blocks AMPK-induced GLUT-4 expression in skeletal muscle.

Journal: American journal of physiology. Cell physiology 20090101

Title: Activation of AMP kinase and inhibition of Rho kinase induce the mineralization of osteoblastic MC3T3-E1 cells through endothelial NOS and BMP-2 expression.

Journal: American journal of physiology. Endocrinology and metabolism 20090101

Title: Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells.

Journal: American journal of physiology. Cell physiology 20090101

Title: AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts.

Journal: BMC pharmacology 20090101

Title: Inhibition of cervical cancer cell growth through activation of upstream kinases of AMP-activated protein kinase.

Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20090101

Title: Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries.

Journal: PloS one 20090101

Title: Genomic characterization of methanomicrobiales reveals three classes of methanogens.

Journal: PloS one 20090101

Title: Modulation of O(2) sensitive K (+) channels by AMP-activated protein kinase.

Journal: Advances in experimental medicine and biology 20090101

Title: Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.

Journal: PloS one 20090101

Title: Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death.

Journal: PloS one 20090101

Title: Effects of angiotensin II receptor blockade on glucose metabolism via AMP-activated protein kinase in insulin-resistant hypertensive rats.

Journal: Journal of the American Society of Hypertension : JASH 20090101

Title: Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas.

Journal: Core evidence 20090101

Title: Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations.

Journal: Cancer management and research 20090101

Title: Structural analysis of the active site geometry of N5-carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.

Journal: Biochemistry 20081216

Title: AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise.

Journal: The Journal of physiology 20081215

Title: Parallel synthesis of an imidazole-4,5-dicarboxamide library bearing amino acid esters and alkanamines.

Journal: Molecules (Basel, Switzerland) 20081215

Title: AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.

Journal: The Journal of biological chemistry 20081205

Title: Synthesis of new carbon-11-labeled carboxamide derivatives as potential PET dopamine D3 receptor radioligands.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20081201

Title: D-ribose therapy in four Polish patients with adenylosuccinate lyase deficiency: absence of positive effect.

Journal: Journal of inherited metabolic disease 20081201

Title: Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20081201

Title: The alpha-subunit of AMPK is essential for submaximal contraction-mediated glucose transport in skeletal muscle in vitro.

Journal: American journal of physiology. Endocrinology and metabolism 20081201

Title: Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes.

Journal: Diabetes 20081201

Title: AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.

Journal: The Journal of physiology 20081201

Title: Adiponectin stimulates phosphorylation of AMP-activated protein kinase alpha in renal glomeruli.

Journal: Journal of molecular histology 20081201

Title: Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20081121

Title: Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cells.

Journal: Biochemical and biophysical research communications 20081121

Title: Stimulation of glucose transport in response to activation of distinct AMPK signaling pathways.

Journal: American journal of physiology. Cell physiology 20081101

Title: Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20081101

Title: Is ZMP the toxic metabolite in Lesch-Nyhan disease?

Journal: Medical hypotheses 20081101

Title: Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.

Journal: Journal of biochemistry 20081101

Title: AICAR decreases the activity of two distinct amiloride-sensitive Na+-permeable channels in H441 human lung epithelial cell monolayers.

Journal: American journal of physiology. Lung cellular and molecular physiology 20081101

Title: Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20081101

Title: Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.

Journal: Diabetes 20081101

Title: Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy.

Journal: Molecular endocrinology (Baltimore, Md.) 20081101

Title: Are 'exercise pills' the answer to the growing problem of physical inactivity?

Journal: British journal of sports medicine 20081101

Title: AMP-activated protein kinase and hypoxic pulmonary vasoconstriction.

Journal: European journal of pharmacology 20081024

Title: The exercise pill--too good to be true?

Journal: The New England journal of medicine 20081023

Title: Validated hydrophilic interaction LC-MS/MS method for simultaneous quantification of dacarbazine and 5-amino-4-imidazole-carboxamide in human plasma.

Journal: Talanta 20081019

Title: AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20081001

Title: Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.

Journal: Diabetes/metabolism research and reviews 20081001

Title: Can patients with type 2 diabetes be treated with 5'-AMP-activated protein kinase activators?

Journal: Diabetologia 20081001

Title: Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients.

Journal: Diabetologia 20081001

Title: The need for a multi-level biochemical approach to defeat cancer that will also support the host.

Journal: Medical hypotheses 20081001

Title: Small molecules can have big effects on endurance.

Journal: Nature chemical biology 20081001

Title: Potential role of lipin-1 in exercise-induced mitochondrial biogenesis.

Journal: Biochemical and biophysical research communications 20080926

Title: The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells.

Journal: Molecular and cellular endocrinology 20080924

Title: Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction.

Journal: Circulation 20080923

Title: AICAR activates AMPK and alters PIP2 association with the epithelial sodium channel ENaC to inhibit Na+ transport in H441 lung epithelial cells.

Journal: The Journal of physiology 20080915

Title: Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.

Journal: Diabetes 20080901

Title: Glucocorticoids increase neuropeptide Y and agouti-related peptide gene expression via adenosine monophosphate-activated protein kinase signaling in the arcuate nucleus of rats.

Journal: Endocrinology 20080901

Title: Crosstalk between the AMP-activated kinase and insulin signaling pathways rescues murine blastocyst cells from insulin resistance.

Journal: Reproduction (Cambridge, England) 20080901

Title: AMP-activated protein kinase agonist dose dependently improves function and reduces apoptosis in glucotoxic beta-cells without changing triglyceride levels.

Journal: Journal of molecular endocrinology 20080901

Title: Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080901

Title: Regulation of ERK1/2 by ouabain and Na-K-ATPase-dependent energy utilization and AMPK activation in parotid acinar cells.

Journal: American journal of physiology. Cell physiology 20080901

Title: Gene polymorphisms and pharmacogenetics in rheumatoid arthritis.

Journal: Current genomics 20080901

Title: AMPK and PPARdelta agonists are exercise mimetics.

Journal: Cell 20080808

Title: Na(+)-K (+) pump location and translocation during muscle contraction in rat skeletal muscle.

Journal: Pflugers Archiv : European journal of physiology 20080801

Title: Cellular energetic status supervises the synthesis of bis-diphosphoinositol tetrakisphosphate independently of AMP-activated protein kinase.

Journal: Molecular pharmacology 20080801

Title: Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance.

Journal: American journal of physiology. Endocrinology and metabolism 20080801

Title: AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast.

Journal: Bone 20080801

Title: Effect of fasting on PPARgamma and AMPK activity in adipocytes.

Journal: Diabetes research and clinical practice 20080801

Title: Synthesis of 3'-deoxy-3'-C-methyl nucleoside derivatives.

Journal: Bioorganic & medicinal chemistry 20080801

Title: Acadesine, an adenosine-regulating agent with the potential for widespread indications.

Journal: Expert opinion on pharmacotherapy 20080801

Title: Can exercise mimetics substitute for exercise?

Journal: Cell metabolism 20080801

Title: A clean-up method by photocatalysis for HPLC analysis of iprodione in dry basil.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080801

Title: Role of AMP-activated protein kinase in the control of appetite.

Journal: Journal of neuroendocrinology 20080701

Title: AM251 suppresses the viability of HepG2 cells through the AMPK (AMP-activated protein kinase)-JNK (c-Jun N-terminal kinase)-ATF3 (activating transcription factor 3) pathway.

Journal: Biochemical and biophysical research communications 20080613

Title: Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.

Journal: Experimental cell research 20080610

Title: Enterostatin inhibition of angiogenesis: possible role of pAMPK and vascular endothelial growth factor A (VEGF-A).

Journal: International journal of obesity (2005) 20080601

Title: AMP-activated protein kinase is essential for survival in chronic hypoxia.

Journal: Biochemical and biophysical research communications 20080530

Title: Role of AMP-activated protein kinase in autophagy and proteasome function.

Journal: Biochemical and biophysical research communications 20080509

Title: Bis(5-amino-4-amino-carbonyl-1H-imid-azol-3-ium) (5-amino-4-amino-carbonyl-1H-imidazol-3-ium-κO)-di-μ-chlorido-hepta-chlorido-dibismuth(III) mono-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20080501

Title: Genotoxic effects of the pesticides Rubigan, Omite and Rovral in root-meristem cells of Crepis capillaris L.

Journal: Mutation research 20080430

Title: Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

Journal: The Journal of biological chemistry 20080411

Title: Rapid analysis of multiple pesticide residues in fruit-based baby food using programmed temperature vaporiser injection-low-pressure gas chromatography-high-resolution time-of-flight mass spectrometry.

Journal: Journal of chromatography. A 20080404

Title: Adiponectin antagonizes stimulatory effect of tumor necrosis factor-alpha on vascular smooth muscle cell calcification: regulation of growth arrest-specific gene 6-mediated survival pathway by adenosine 5'-monophosphate-activated protein kinase.

Journal: Endocrinology 20080401

Title: 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

Journal: Endocrinology 20080401

Title: Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats.

Journal: American journal of physiology. Renal physiology 20080401

Title: alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments.

Journal: The Journal of biological chemistry 20080314

Title: AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20080307

Title: Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver.

Journal: Biochimie 20080301

Title: Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes.

Journal: Molecular endocrinology (Baltimore, Md.) 20080301

Title: AMPK activation attenuates S6K1, 4E-BP1, and eEF2 signaling responses to high-frequency electrically stimulated skeletal muscle contractions.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080301

Title: The effect of AMP-activated kinase activation on gonadotrophin-releasing hormone secretion in GT1-7 cells and its potential role in hypothalamic regulation of the oestrous cyclicity in rats.

Journal: Journal of neuroendocrinology 20080301

Title: Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080301

Title: SIK2 can be activated by deprivation of nutrition and it inhibits expression of lipogenic genes in adipocytes.

Journal: Obesity (Silver Spring, Md.) 20080301

Title: Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells.

Journal: Investigative ophthalmology & visual science 20080301

Title: AMP-activated protein kinase activation by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) inhibits palmitate-induced endothelial cell apoptosis through reactive oxygen species suppression.

Journal: Journal of pharmacological sciences 20080301

Title: Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase.

Journal: Journal of cellular biochemistry 20080215

Title: IGF-1 receptor signaling pathways and effects of AMPK activation on IGF-1-induced progesterone secretion in hen granulosa cells.

Journal: Domestic animal endocrinology 20080201

Title: Contrasting effects of exercise, AICAR, and increased fatty acid supply on in vivo and skeletal muscle glucose metabolism.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080201

Title: AMP-activated protein kinase phosphorylates transcription factors of the CREB family.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080201

Title: Adenosine monophosphate-activated protein kinase modulates the activated phenotype of hepatic stellate cells.

Journal: Hepatology (Baltimore, Md.) 20080201

Title: High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase.

Journal: Hepatology (Baltimore, Md.) 20080201

Title: Physiological glucose is critical for optimized neuronal viability and AMPK responsiveness in vitro.

Journal: Journal of neuroscience methods 20080130

Title: Transcriptional mechanism of suppression of insulin gene expression by AMP-activated protein kinase activator 5-amino-4-imidazolecarboxamide riboside (AICAR) in beta-cells.

Journal: Biochemical and biophysical research communications 20080125

Title: Effect of alcohols on the stability of iprodione in solution.

Journal: Journal of agricultural and food chemistry 20080123

Title: AICAR positively regulate glycogen synthase activity and LDL receptor expression through Raf-1/MEK/p42/44MAPK/p90RSK/GSK-3 signaling cascade.

Journal: Biochemical pharmacology 20080115

Title: AMPK activation with AICAR provokes an acute fall in plasma [K+].

Journal: American journal of physiology. Cell physiology 20080101

Title: Chemical hypoxia-induced glucose transporter-4 translocation in neonatal rat cardiomyocytes.

Journal: Archives of medical research 20080101

Title: Molecular characterization of benzimidazole-resistant isolates of Cladosporium fulvum.

Journal: FEMS microbiology letters 20080101

Title: Live or let die: E2F1 and PI3K pathways intersect to make life or death decisions.

Journal: Cancer cell 20080101

Title: An E2F1-dependent gene expression program that determines the balance between proliferation and cell death.

Journal: Cancer cell 20080101

Title: Clinical, biochemical, neuropathological and molecular findings of the first Polish case of adenylosuccinase deficiency.

Journal: Folia neuropathologica 20080101

Title: Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.

Journal: PloS one 20080101

Title: Acadesine: AICA riboside, ARA 100, arasine, GP 1 110.

Journal: Drugs in R&D 20080101

Title: AMPK alpha1 activation is required for stimulation of glucose uptake by twitch contraction, but not by H2O2, in mouse skeletal muscle.

Journal: PloS one 20080101

Title: Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain.

Journal: Molecular cancer 20080101

Title: Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK.

Journal: BMC immunology 20080101

Title: AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells.

Journal: PloS one 20080101

Title: Central exercise action increases the AMPK and mTOR response to leptin.

Journal: PloS one 20080101

Title: Vasopressin regulates the phosphorylation state of AMP-activated protein kinase (AMPK) in MDCK-C7 cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: AICAR induces phosphorylation of AMPK in an ATM-dependent, LKB1-independent manner.

Journal: Molecular and cellular biochemistry 20071201

Title: LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20071201

Title: Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling.

Journal: American journal of physiology. Endocrinology and metabolism 20071201

Title: AICAR inhibits proliferation and induced S-phase arrest, and promotes apoptosis in CaSki cells.

Journal: Acta pharmacologica Sinica 20071201

Title: 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICA-riboside) as a targeting agent for therapy of patients with acute lymphoblastic leukemia: are we there and are there pitfalls?

Journal: Journal of pediatric hematology/oncology 20071201

Title: Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes.

Journal: Current diabetes reports 20071201

Title: Maternal diabetes adversely affects AMP-activated protein kinase activity and cellular metabolism in murine oocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20071101

Title: Ceramide and adenosine 5'-monophosphate-activated protein kinase are two novel regulators of 11beta-hydroxysteroid dehydrogenase type 1 expression and activity in cultured preadipocytes.

Journal: Endocrinology 20071101

Title: Lack of AMPKalpha2 enhances pyruvate dehydrogenase activity during exercise.

Journal: American journal of physiology. Endocrinology and metabolism 20071101

Title: A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia.

Journal: Endocrinology 20071101

Title: Five-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates poly (I:C)-induced airway inflammation in a murine model of asthma.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20071101

Title: Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production.

Journal: Toxicology letters 20071101

Title: Dissociation of AMP-activated protein kinase and p38 mitogen-activated protein kinase signaling in skeletal muscle.

Journal: Biochemical and biophysical research communications 20071019

Title: Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR.

Journal: The Biochemical journal 20071015

Title: Differential involvement of histidine kinase receptors in pseudohyphal development, stress adaptation, and drug sensitivity of the opportunistic yeast Candida lusitaniae.

Journal: Eukaryotic cell 20071001

Title: Nitric oxide increases GLUT4 expression and regulates AMPK signaling in skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20071001

Title: Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells.

Journal: Experimental cell research 20071001

Title: Proteomics analysis of hypothalamic response to energy restriction in dairy cows.

Journal: Proteomics 20071001

Title: The AMP-activated protein kinase activator, 5-aminoimidazole-4-carboxamide-1-b-D-ribonucleoside, regulates lactate production in rat Sertoli cells.

Journal: Journal of molecular endocrinology 20071001

Title: Structural insight into AMPK regulation: ADP comes into play.

Journal: Structure (London, England : 1993) 20071001

Title: A pharmacological activator of AMP-activated protein kinase (AMPK) induces astrocyte stellation.

Journal: Brain research 20070907

Title: AMP kinase activation increases glucose uptake, decreases apoptosis, and improves pregnancy outcome in embryos exposed to high IGF-I concentrations.

Journal: Diabetes 20070901

Title: Upregulation of IL-6 mRNA by IL-6 in skeletal muscle cells: role of IL-6 mRNA stabilization and Ca2+-dependent mechanisms.

Journal: American journal of physiology. Cell physiology 20070901

Title: Airway smooth muscle proliferation and mechanics: effects of AMP kinase agonists.

Journal: Molecular & cellular biomechanics : MCB 20070901

Title: Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha.

Journal: Experimental & molecular medicine 20070831

Title: Fatty acid synthase gene regulation in primary hypothalamic neurons.

Journal: Neuroscience letters 20070823

Title: Determination of 5-aminoimidazole-4-carboxamide in human plasma by ion-pair extraction and LC-MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815

Title: Effects of adenosine monophosphate-activated kinase activators on bovine oocyte nuclear maturation in vitro.

Journal: Molecular reproduction and development 20070801

Title: Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.

Journal: The Journal of investigative dermatology 20070801

Title: 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men.

Journal: Diabetes 20070801

Title: Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle.

Journal: The Journal of physiology 20070801

Title: Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.

Journal: British journal of pharmacology 20070801

Title: 5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside stimulates tyrosine hydroxylase activity and catecholamine secretion by activation of AMP-activated protein kinase in PC12 cells.

Journal: Journal of neuroendocrinology 20070801

Title: Covariate heterogeneity in meta-analysis: criteria for deciding between meta-regression and individual patient data.

Journal: Statistics in medicine 20070710

Title: AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes.

Journal: Bioscience, biotechnology, and biochemistry 20070701

Title: [Quantum chemistry study on fluorescence spectra of three aromatic hydrocarbons].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20070701

Title: AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside.

Journal: The Biochemical journal 20070615

Title: Activation of AMP kinase alpha1 subunit induces aortic vasorelaxation in mice.

Journal: The Journal of physiology 20070615

Title: Neurotensin receptor binding and neurotensin-induced growth signaling in prostate cancer PC3 cells are sensitive to metabolic stress.

Journal: Regulatory peptides 20070607

Title: AMP-activated protein kinase agonists increase mRNA content of the muscle-specific ubiquitin ligases MAFbx and MuRF1 in C2C12 cells.

Journal: American journal of physiology. Endocrinology and metabolism 20070601

Title: A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism.

Journal: American journal of physiology. Endocrinology and metabolism 20070601

Title: Activation of AMP-activated protein kinase stimulates proopiomelanocortin gene transcription in AtT20 corticotroph cells.

Journal: American journal of physiology. Endocrinology and metabolism 20070601

Title: Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070601

Title: S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase.

Journal: Cell metabolism 20070601

Title: Preparation and characterization of inclusion complex of iprodione and beta-cyclodextrin to improve fungicidal activity.

Journal: Journal of agricultural and food chemistry 20070502

Title: Role of glycogen content in insulin resistance in human muscle cells.

Journal: Journal of cellular physiology 20070501

Title: Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of LKB1.

Journal: The Biochemical journal 20070501

Title: Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction.

Journal: American journal of physiology. Endocrinology and metabolism 20070501

Title: A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.

Journal: Biochemistry 20070501

Title: Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.

Journal: Acta crystallographica. Section D, Biological crystallography 20070501

Title: 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.

Journal: Molecular cancer therapeutics 20070501

Title: Resveratrol stimulates AMP kinase activity in neurons.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20070424

Title: An analogue of AICAR with dual inhibitory activity against WNV and HCV NTPase/helicase: synthesis and in vitro screening of 4-carbamoyl-5-(4,6-diamino-2,5-dihydro-1,3,5-triazin-2-yl)imidazole-1-beta-D-ribofuranoside.

Journal: Bioorganic & medicinal chemistry letters 20070415

Title: AICAR potentiates ROS production induced by chronic high glucose: roles of AMPK in pancreatic beta-cell apoptosis.

Journal: Cellular signalling 20070401

Title: Adenosine 5'-monophosphate kinase-activated protein kinase (PRKA) activators delay meiotic resumption in porcine oocytes.

Journal: Biology of reproduction 20070401

Title: Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070401

Title: Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinase.

Journal: Journal of animal science 20070401

Title: Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy.

Journal: Journal of cellular biochemistry 20070401

Title: Determination of iprodione in agrochemicals by infrared and Raman spectrometry.

Journal: Analytical and bioanalytical chemistry 20070401

Title: AMP-activated protein kinase mediates carotid body excitation by hypoxia.

Journal: The Journal of biological chemistry 20070316

Title: Meiotic induction by heat stress in mouse oocytes: involvement of AMP-activated protein kinase and MAPK family members.

Journal: Biology of reproduction 20070301

Title: Effect of acute activation of 5'-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscle.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070301

Title: Effects of metformin on bovine granulosa cells steroidogenesis: possible involvement of adenosine 5' monophosphate-activated protein kinase (AMPK).

Journal: Biology of reproduction 20070301

Title: Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia.

Journal: Endocrinology 20070301

Title: Roles of putative His-to-Asp signaling modules HPT-1 and RRG-2, on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa.

Journal: Current genetics 20070301

Title: Addition of adenosine monophosphate-activated protein kinase activators to University of Wisconsin solution: a way of protecting rat steatotic livers.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070301

Title: Characterization of the NikA histidine kinase implicated in the phosphorelay signal transduction of Aspergillus nidulans, with special reference to fungicide responses.

Journal: Bioscience, biotechnology, and biochemistry 20070301

Title: The role of AMP kinase in diabetes.

Journal: The Indian journal of medical research 20070301

Title: Inhibition of hepatic phosphatidylcholine synthesis by 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside is independent of AMP-activated protein kinase activation.

Journal: The Journal of biological chemistry 20070216

Title: AMP-activated protein kinase in metabolic control and insulin signaling.

Journal: Circulation research 20070216

Title: Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis.

Journal: Cell metabolism 20070207

Title: Immunoassay for iprodione: key estimation for residue analysis and method validation with chromatographic technique.

Journal: Analytica chimica acta 20070205

Title: Fluid shear stress and NO decrease the activity of the hydroxy-methylglutaryl coenzyme A reductase in endothelial cells via the AMP-activated protein kinase and FoxO1.

Journal: Circulation research 20070202

Title: A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy.

Journal: American journal of physiology. Renal physiology 20070201

Title: Glucose-transport regulation in leukemic cells: how can H2O2 mimic stem cell factor effects?

Journal: Antioxidants & redox signaling 20070201

Title: Two-component response regulators Ssk1p and Skn7p additively regulate high-osmolarity adaptation and fungicide sensitivity in Cochliobolus heterostrophus.

Journal: Eukaryotic cell 20070201

Title: Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase.

Journal: American journal of physiology. Cell physiology 20070101

Title: 5'-AMP-activated protein kinase activation prevents postischemic leukocyte-endothelial cell adhesive interactions.

Journal: American journal of physiology. Heart and circulatory physiology 20070101

Title: Critical role of 5'-AMP-activated protein kinase in the stimulation of glucose transport in response to inhibition of oxidative phosphorylation.

Journal: American journal of physiology. Cell physiology 20070101

Title: Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20070101

Title: Influence of humic substances on the photolysis of aqueous pesticide residues.

Journal: Chemosphere 20070101

Title: Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity.

Journal: Diabetologia 20070101

Title: Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation.

Journal: Free radical biology & medicine 20070101

Title: Analysis of 3,5-dichloroaniline as a biomarker of vinclozolin and iprodione in human urine using liquid chromatography/triple quadrupole mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells.

Journal: Annals of the New York Academy of Sciences 20070101

Title: Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis risk.

Journal: Clinical chemistry and laboratory medicine 20070101

Title: Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.

Journal: Molecular cancer 20070101

Title: Identification of new reference genes for the normalisation of canine osteoarthritic joint tissue transcripts from microarray data.

Journal: BMC molecular biology 20070101

Title: Formamide as the main building block in the origin of nucleic acids.

Journal: BMC evolutionary biology 20070101

Title: [Pemetrexed: from preclinic to clinic].

Journal: Bulletin du cancer 20070101

Title: Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

Journal: BMC biochemistry 20070101

Title: Solid phase synthesis of nucleobase and ribose modified inosine nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids 20070101

Title: [Occurrence of pesticide residues in raspberries in 2000-2005].

Journal: Roczniki Panstwowego Zakladu Higieny 20070101

Title: Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead.

Journal: Journal of medicinal chemistry 20061228

Title: [Effects of globular adiponectin, glucose and free fatty acid on AMPK and ACC phosphorylation in INS-1 beta cells].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20061218

Title: Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver.

Journal: Molecular pharmacology 20061201

Title: AMP-activated protein kinase and the regulation of autophagic proteolysis.

Journal: The Journal of biological chemistry 20061117

Title: Inhibition of fructose-1,6-bisphosphatase by aminoimidazole carboxamide ribotide prevents growth of Salmonella enterica purH mutants on glycerol.

Journal: The Journal of biological chemistry 20061110

Title: Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion.

Journal: American journal of physiology. Endocrinology and metabolism 20061101

Title: Inhibition of insulin-stimulated glycogen synthesis by 5-aminoimidasole-4-carboxamide-1-beta-d-ribofuranoside-induced adenosine 5'-monophosphate-activated protein kinase activation: interactions with Akt, glycogen synthase kinase 3-3alpha/beta, and glycogen synthase in isolated rat soleus muscle.

Journal: Endocrinology 20061101

Title: AICAR inhibits the Na+/H+ exchanger in rat hearts--possible contribution to cardioprotection.

Journal: Pflugers Archiv : European journal of physiology 20061101

Title: Feasibility of LC/TOFMS and elemental database searching as a spectral library for pesticides in food.

Journal: Food additives and contaminants 20061101

Title: The effects of 5-aminoimidazole-4-carboxamide riboside on the pancreas in neonatal streptozotocin-diabetic rats.

Journal: Acta diabetologica 20061101

Title: Application of comprehensive two-dimensional gas chromatography with nitrogen-selective detection for the analysis of fungicide residues in vegetable samples.

Journal: Journal of chromatography. A 20061027

Title: Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20061027

Title: Diagnosing AICA-ribosiduria by capillary electrophoresis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020

Title: Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells.

Journal: Cancer research 20061015

Title: TRIP6 transcriptional co-activator is a novel substrate of AMP-activated protein kinase.

Journal: Cellular signalling 20061001

Title: Molecular characterization of the two-component histidine kinase gene from Monilinia fructicola.

Journal: Pest management science 20061001

Title: Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase.

Journal: Diabetes 20061001

Title: Rosiglitazone treatment enhances acute AMP-activated protein kinase-mediated muscle and adipose tissue glucose uptake in high-fat-fed rats.

Journal: Diabetes 20061001

Title: Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.

Journal: Arthritis and rheumatism 20061001

Title: Increased ATP-sensitive K+ channel expression during acute glucose deprivation.

Journal: Biochemical and biophysical research communications 20060929

Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-induced AMP-activated protein kinase phosphorylation inhibits basal and insulin-stimulated glucose uptake, lipid synthesis, and fatty acid oxidation in isolated rat adipocytes.

Journal: The Journal of biological chemistry 20060908

Title: Muscle-specific overexpression of wild type and R225Q mutant AMP-activated protein kinase gamma3-subunit differentially regulates glycogen accumulation.

Journal: American journal of physiology. Endocrinology and metabolism 20060901

Title: Induction of meiotic maturation in mouse oocytes by adenosine analogs.

Journal: Molecular reproduction and development 20060901

Title: The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans.

Journal: The Journal of clinical endocrinology and metabolism 20060901

Title: Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.

Journal: The American journal of pathology 20060901

Title: The PPAR gamma agonist troglitazone induces musclin mRNA expression in human myotubes.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901

Title: Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.

Journal: Molecular cancer therapeutics 20060901

Title: 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction.

Journal: Journal of neuroscience research 20060815

Title: Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1beta converting enzyme (ICE) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20060815

Title: Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060802

Title: Prolonged AMPK activation increases the expression of fatty acid transporters in cardiac myocytes and perfused hearts.

Journal: Molecular and cellular biochemistry 20060801

Title: Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta.

Journal: Molecular and cellular biology 20060801

Title: Biochemical and structural studies of N5-carboxyaminoimidazole ribonucleotide mutase from the acidophilic bacterium Acetobacter aceti.

Journal: Biochemistry 20060711

Title: Post-reperfusion myocardial infarction: long-term survival improvement using adenosine regulation with acadesine.

Journal: Journal of the American College of Cardiology 20060704

Title: Moving preconditioning from bench to bedside.

Journal: Journal of the American College of Cardiology 20060704

Title: Time course changes in signaling pathways and protein synthesis in C2C12 myotubes following AMPK activation by AICAR.

Journal: American journal of physiology. Endocrinology and metabolism 20060701

Title: AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

Journal: Diabetes 20060701

Title: Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.

Journal: Diabetes 20060701

Title: S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase.

Journal: Gastroenterology 20060701

Title: AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles.

Journal: The Journal of endocrinology 20060701

Title: Biodegradation of the fungicide iprodione by Zygosaccharomyces rouxii strain DBVPG 6399.

Journal: Journal of agricultural and food chemistry 20060628

Title: Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine.

Journal: Journal of lipid research 20060601

Title: Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20060601

Title: Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation.

Journal: Diabetes 20060601

Title: Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway.

Journal: Diabetes 20060601

Title: AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

Journal: Biochemical pharmacology 20060528

Title: Cytokine secretion by human adipocytes is differentially regulated by adiponectin, AICAR, and troglitazone.

Journal: Biochemical and biophysical research communications 20060512

Title: Human resistin promotes macrophage lipid accumulation.

Journal: Diabetologia 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: AMPK activation inhibits the expression of HIF-1alpha induced by insulin and IGF-1.

Journal: Biochemical and biophysical research communications 20060421

Title: Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases.

Journal: The Biochemical journal 20060401

Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation.

Journal: Diabetes 20060401

Title: 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.

Journal: Cancer research 20060401

Title: AMPK regulation of mouse oocyte meiotic resumption in vitro.

Journal: Developmental biology 20060315

Title: Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue.

Journal: American journal of physiology. Endocrinology and metabolism 20060301

Title: Relationship between 5-aminoimidazole-4-carboxamide-ribotide and AMP-activated protein kinase activity in the perfused mouse heart.

Journal: American journal of physiology. Heart and circulatory physiology 20060301

Title: Oleic acid uptake by in vitro English sparrow skeletal muscle.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20060301

Title: α2 isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal muscle.

Journal: Metabolism: clinical and experimental 20060301

Title: AMP-activated protein kinase activation by adrenoceptors in L6 skeletal muscle cells: mediation by alpha1-adrenoceptors causing glucose uptake.

Journal: Diabetes 20060301

Title: AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

Journal: Biochemical and biophysical research communications 20060203

Title: AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2alpha in adipocytes.

Journal: Biochemical and biophysical research communications 20060203

Title: Role of 5'-AMP-activated protein kinase in stimulation of glucose transport in response to inhibition of oxidative phosphorylation.

Journal: American journal of physiology. Cell physiology 20060201

Title: Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells.

Journal: Journal of lipid research 20060201

Title: Activation of AMP-activated protein kinase enhances angiotensin ii-induced proliferation in cardiac fibroblasts.

Journal: Hypertension (Dallas, Tex. : 1979) 20060201

Title: Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells.

Journal: Immunology and cell biology 20060201

Title: Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.

Journal: Diabetes 20060201

Title: Development of an SPME-GC-MS/MS method for the determination of pesticides in rainwater: laboratory and field experiments.

Journal: Environmental pollution (Barking, Essex : 1987) 20060101

Title: Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells.

Journal: Diabetes 20060101

Title: A pull-down assay for 5' AMP-activated protein kinase activity using the GST-fused protein.

Journal: Molecular biotechnology 20060101

Title: AMP-activated protein kinase and type 2 diabetes.

Journal: Current medicinal chemistry 20060101

Title: Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis.

Journal: Arthritis research & therapy 20060101

Title: Does AMP-activated protein kinase couple hypoxic inhibition of oxidative phosphorylation to carotid body excitation?

Journal: Advances in experimental medicine and biology 20060101

Title: AMPK or ZMPK?

Journal: Medical hypotheses 20060101

Title: Bioefficacy of iprodione against two desapers, its compatibility with T. harzianum and residues on cabbage crop.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20060101

Title: Analysis of intracellular nucleotides by capillary electrophoresis-mass spectrometry.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Synthesis and mass spectrometric fragmentation characteristics of imidazole ribosides-analogs of intermediates of purine de novo synthetic pathway.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: 5 '-Amino-4-imidazolecarboxamide riboside induces apoptosis in human neuroblastoma cells via the mitochondrial pathway.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Determination and validation of a simple high-performance liquid chromatographic method for simultaneous assay of iprodione and vinclozolin in human urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051215

Title: Indole-2-carboxamidines as novel NR2B selective NMDA receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20051215

Title: A role for hypothalamic malonyl-CoA in the control of food intake.

Journal: The Journal of biological chemistry 20051202

Title: AICAR stimulates IL-6 production via p38 MAPK in cardiac fibroblasts in adult mice: a possible role for AMPK.

Journal: Biochemical and biophysical research communications 20051202

Title: Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase.

Journal: American journal of physiology. Endocrinology and metabolism 20051201

Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside renders glucose output by the liver of the dog insensitive to a pharmacological increment in insulin.

Journal: American journal of physiology. Endocrinology and metabolism 20051201

Title: Sorption, degradation and leaching of the fungicide iprodione in a golf green under Scandinavian conditions: measurements, modelling and risk assessment.

Journal: Pest management science 20051201

Title: Adenosine monophosphate-activated protein kinase and nitric oxide in rat steatotic liver transplantation.

Journal: Journal of hepatology 20051201

Title: Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase.

Journal: American journal of physiology. Endocrinology and metabolism 20051201

Title: Fine-tuning insulin and nitric oxide signalling by turning up the AMPs: new insights into AMP-activated protein kinase signalling.

Journal: Diabetologia 20051201

Title: Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo.

Journal: Diabetologia 20051201

Title: AICAR, an AMPK activator, has protective effects on alcohol-induced fatty liver in rats.

Journal: Alcoholism, clinical and experimental research 20051201

Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20051125

Title: AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle.

Journal: The Journal of biological chemistry 20051125

Title: AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.

Journal: Circulation research 20051028

Title: Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.

Journal: Circulation research 20051014

Title: Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20051001

Title: DNA-bound Bas1 recruits Pho2 to activate ADE genes in Saccharomyces cerevisiae.

Journal: Eukaryotic cell 20051001

Title: AICAR and hyperosmotic stress increase insulin-stimulated glucose transport.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20050901

Title: Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle.

Journal: The Journal of physiology 20050901

Title: Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase.

Journal: European journal of pharmacology 20050822

Title: The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.

Journal: The Journal of biological chemistry 20050812

Title: Phenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells.

Journal: The Journal of physiology 20050801

Title: Adiponectin-mediated stimulation of AMP-activated protein kinase (AMPK) in pancreatic beta cells.

Journal: Life sciences 20050729

Title: Techniques and parameters used in compatibility tests between Beauveria bassiana (Bals) Vuill and in vitro phytosanitary products.

Journal: Pest management science 20050701

Title: Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes.

Journal: The Journal of biological chemistry 20050701

Title: Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701

Title: AICAR suppresses IL-2 expression through inhibition of GSK-3 phosphorylation and NF-AT activation in Jurkat T cells.

Journal: Biochemical and biophysical research communications 20050701

Title: 5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050701

Title: The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.

Journal: Oncogene 20050616

Title: Contraction- and hypoxia-stimulated glucose transport is mediated by a Ca2+-dependent mechanism in slow-twitch rat soleus muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20050601

Title: AMP kinase activation with AICAR further increases fatty acid oxidation and blunts triacylglycerol hydrolysis in contracting rat soleus muscle.

Journal: The Journal of physiology 20050601

Title: AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscle.

Journal: The Journal of physiology 20050601

Title: Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.

Journal: Diabetologia 20050601

Title: Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke.

Journal: The Journal of biological chemistry 20050527

Title: 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.

Journal: Biochemical and biophysical research communications 20050520

Title: Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.

Journal: The EMBO journal 20050518

Title: Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside.

Journal: American journal of physiology. Endocrinology and metabolism 20050501

Title: Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule.

Journal: Genetics 20050501

Title: Molecular mechanism of the aryl hydrocarbon receptor activation by the fungicide iprodione in rainbow trout (Oncorhynchus mykiss) hepatocytes.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050430

Title: AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle.

Journal: Circulation research 20050429

Title: The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR.

Journal: FEBS letters 20050425

Title: Long-term AICAR administration and exercise prevents diabetes in ZDF rats.

Journal: Diabetes 20050401

Title: N-Arylpiperazine-1-carboxamide derivatives: a novel series of orally active nonsteroidal androgen receptor antagonists.

Journal: Chemical & pharmaceutical bulletin 20050401

Title: Synthesis of a methylene analog of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide monophosphate (ZMP).

Journal: Bioscience, biotechnology, and biochemistry 20050401

Title: A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis.

Journal: The Journal of biological chemistry 20050325

Title: Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype.

Journal: Cancer research 20050315

Title: AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells.

Journal: Biochemical and biophysical research communications 20050311

Title: Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins.

Journal: The Biochemical journal 20050301

Title: AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction.

Journal: American journal of physiology. Endocrinology and metabolism 20050301

Title: Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism.

Journal: Diabetes 20050301

Title: Dual mechanisms regulating AMPK kinase action in the ischemic heart.

Journal: Circulation research 20050218

Title: AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.

Journal: The Journal of biological chemistry 20050211

Title: Depression of cell metabolism and proliferation by membrane-permeable and -impermeable modulators: role for AMP-to-ATP ratio.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050201

Title: Acadesine induces apoptosis in B cells from mantle cell lymphoma and splenic marginal zone lymphoma.

Journal: Leukemia 20050201

Title: MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism.

Journal: Molecular reproduction and development 20050201

Title: Glucose transport by English sparrow (Passer domesticus) skeletal muscle: have we been chirping up the wrong tree?

Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20050201

Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside causes acute hepatic insulin resistance in vivo.

Journal: Diabetes 20050201

Title: Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output.

Journal: Diabetes 20050201

Title: Base cation stimulation of mycorrhization and photosynthesis of sugar maple on acid soils are coupled by foliar nutrient dynamics.

Journal: The New phytologist 20050201

Title: Demonstration of an alternative mechanism for G-to-G cross-link formation.

Journal: Journal of the American Chemical Society 20050126

Title: Mechanism of action of Escherichia coli phosphoribosylaminoimidazolesuccinocarboxamide synthetase.

Journal: Biochemistry 20050118

Title: 5-aminoimidazole-4-carboxamide riboside (AICAR) enhances GLUT2-dependent jejunal glucose transport: a possible role for AMPK.

Journal: The Biochemical journal 20050115

Title: Role of neuronal energy status in the regulation of adenosine 5'-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior.

Journal: Endocrinology 20050101

Title: Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity.

Journal: Diabetes 20050101

Title: Preparation of 5-amino-4-imidazole-N-succinocarboxamide ribotide, 5-amino-4-imidazole-N-succinocarboxamide riboside and succinyladenosine, compounds usable in diagnosis and research of adenylosuccinate lyase deficiency.

Journal: Journal of inherited metabolic disease 20050101

Title: One-bead-one-compound library of end-capped dipeptides and deconvolution by microflow NMR.

Journal: Journal of combinatorial chemistry 20050101

Title: Ring opening reactions: synthesis of AICAR analogs as potential antimetabolite agents.

Journal: Nucleosides, nucleotides & nucleic acids 20050101

Title: Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.

Journal: Journal of medicinal chemistry 20041230

Title: Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor alpha by AMP-activated protein kinase.

Journal: The Biochemical journal 20041201

Title: Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041201

Title: The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.

Journal: Diabetes 20041201

Title: Mapping of the bovine genes of the de novo AMP synthesis pathway.

Journal: Animal genetics 20041201

Title: The role of AMP-activated protein kinase in the action of ethanol in the liver.

Journal: Gastroenterology 20041201

Title: AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

Journal: The Journal of biological chemistry 20041112

Title: AMPK stimulation increases LCFA but not glucose clearance in cardiac muscle in vivo.

Journal: American journal of physiology. Endocrinology and metabolism 20041101

Title: Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20041101

Title: Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition.

Journal: Diabetologia 20041101

Title: AMP kinase is not required for the GLUT4 response to exercise and denervation in skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20041001

Title: Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.

Journal: Circulation research 20041001

Title: The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.

Journal: Arthritis and rheumatism 20041001

Title: Adenylosuccinate lyase deficiency--first British case.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Cytotoxicity of the dicarboximide fungicides, vinclozolin and iprodione, in rat hepatoma-derived Fa32 cells.

Journal: Alternatives to laboratory animals : ATLA 20041001

Title: Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation.

Journal: Transplantation 20040915

Title: Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake.

Journal: American journal of physiology. Endocrinology and metabolism 20040901

Title: Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis.

Journal: Endocrinology 20040901

Title: Effect of fungicide iprodione on soil bacterial community.

Journal: Ecotoxicology and environmental safety 20040901

Title: AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females.

Journal: The Journal of clinical endocrinology and metabolism 20040901

Title: Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis.

Journal: Arthritis and rheumatism 20040901

Title: Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils.

Journal: FEBS letters 20040827

Title: AMP-activated protein kinase: the guardian of cardiac energy status.

Journal: The Journal of clinical investigation 20040816

Title: AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms.

Journal: Biochemical and biophysical research communications 20040813

Title: Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.

Journal: Endocrinology 20040801

Title: Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

Journal: American journal of physiology. Endocrinology and metabolism 20040801

Title: Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.

Journal: Diabetes 20040801

Title: Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.

Journal: The Journal of biological chemistry 20040730

Title: AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation.

Journal: Circulation 20040727

Title: AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo.

Journal: Diabetes 20040701

Title: Sending the signal: molecular mechanisms regulating glucose uptake.

Journal: Medicine and science in sports and exercise 20040701

Title: 5'-aminoimidazole-4-carboxyamide-ribonucleoside-activated glucose transport is not prevented by nitric oxide synthase inhibition in rat isolated skeletal muscle.

Journal: Clinical and experimental pharmacology & physiology 20040701

Title: Insulin-nonspecific reduction in skeletal muscle glucose transport in high-fat-fed rats.

Journal: Metabolism: clinical and experimental 20040701

Title: MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways.

Journal: American journal of physiology. Cell physiology 20040601

Title: AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC.

Journal: American journal of human genetics 20040601

Title: AMP kinase-induced skeletal muscle glucose but not long-chain fatty acid uptake is dependent on nitric oxide.

Journal: Diabetes 20040601

Title: Preliminary study on pharmacokinetics of dacarbazine and fotemustine in glioblastoma multiforme patients does not indicate gender-specific differences.

Journal: Anti-cancer drugs 20040601

Title: 5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages.

Journal: Biochemical and biophysical research communications 20040528

Title: Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.

Journal: Biochemical pharmacology 20040515

Title: C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20040507

Title: A glucose response element from the S. cerevisiae hexose transporter HXT1 gene is sensitive to glucose in human fibroblasts.

Journal: Journal of molecular biology 20040507

Title: Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status.

Journal: The Journal of biological chemistry 20040416

Title: AICAR stimulates adiponectin and inhibits cytokines in adipose tissue.

Journal: Biochemical and biophysical research communications 20040409

Title: Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates.

Journal: The Journal of biological chemistry 20040326

Title: AMP-activated protein kinase plays a role in the control of food intake.

Journal: The Journal of biological chemistry 20040326

Title: Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

Journal: The Biochemical journal 20040315

Title: AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.

Journal: Journal of neurochemistry 20040301

Title: Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells exposed to iprodione.

Journal: International journal of environmental research and public health 20040301

Title: Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.

Journal: Biochemistry 20040210

Title: Effects of acute bouts of running and swimming exercise on PGC-1alpha protein expression in rat epitrochlearis and soleus muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20040201

Title: Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions.

Journal: Diabetes 20040201

Title: [The antiandrogenic effect of dimethachlon and its mechanism].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040201

Title: 5-Aminoimidazole-4-carboxamide-ribonucleoside enhances oxidative stress-induced apoptosis through activation of nuclear factor-kappaB in mouse Neuro 2a neuroblastoma cells.

Journal: Neuroscience letters 20040116

Title: Multiple independent kinase cascades are targeted by hyperosmotic stress but only one activates stress kinase p38.

Journal: Experimental cell research 20040115

Title: 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040114

Title: Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

Journal: The Journal of biological chemistry 20040109

Title: Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose.

Journal: The Biochemical journal 20040101

Title: Dicarboximide resistance in field isolates of Alternaria alternata is mediated by a mutation in a two-component histidine kinase gene.

Journal: Fungal genetics and biology : FG & B 20040101

Title: Adsorption, transformation, and bioavailability of the fungicides carbendazim and iprodione in soil, alone and in combination.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040101

Title: AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets.

Journal: Thrombosis and haemostasis 20031101

Title: Effects of chronic AICAR administration on the metabolic and contractile phenotypes of rat slow- and fast-twitch skeletal muscles.

Journal: Canadian journal of physiology and pharmacology 20031101

Title: Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes.

Journal: The Journal of biological chemistry 20031003

Title: Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients.

Journal: Diabetologia 20031001

Title: Small molecule inhibition of hepatitis C virus E2 binding to CD81.

Journal: Virology 20030915

Title: Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030901

Title: Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.

Journal: Endocrinology 20030901

Title: The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901

Title: Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells.

Journal: The Journal of biological chemistry 20030822

Title: AMPK activation increases uncoupling protein-3 expression and mitochondrial enzyme activities in rat muscle without fibre type transitions.

Journal: The Journal of physiology 20030815

Title: AMP-activated protein kinase and muscle glucose uptake.

Journal: Acta physiologica Scandinavica 20030801

Title: AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise.

Journal: Acta physiologica Scandinavica 20030801

Title: Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.

Journal: The Journal of biological chemistry 20030718

Title: Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes.

Journal: The Biochemical journal 20030715

Title: Intrafamilial variability in the phenotypic expression of adenylosuccinate lyase deficiency: a report on three patients.

Journal: American journal of medical genetics. Part A 20030715

Title: Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling.

Journal: Diabetes 20030701

Title: PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations.

Journal: American journal of physiology. Cell physiology 20030601

Title: Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells.

Journal: The Journal of biological chemistry 20030516

Title: Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.

Journal: Blood 20030501

Title: 5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.

Journal: Diabetes 20030501

Title: [Physiological roles of AMP-activated protein kinase (AMPK)].

Journal: Medecine sciences : M/S 20030501

Title: Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030401

Title: 5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030401

Title: AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase.

Journal: Journal of molecular endocrinology 20030401

Title: 5-Aminoimidazole-4-carboxamide riboside induces apoptosis in Jurkat cells, but the AMP-activated protein kinase is not involved.

Journal: The Biochemical journal 20030315

Title: Persistence and effectiveness of iprodione against Alternaria blight in mustard.

Journal: Bulletin of environmental contamination and toxicology 20030301

Title: Multiresidue pesticide analysis in wines by solid-phase extraction and capillary gas chromatography-mass spectrometric detection with selective ion monitoring.

Journal: Journal of agricultural and food chemistry 20030226

Title: Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.

Journal: Biochemistry 20030225

Title: A possible role for AMP-activated protein kinase in exercise-induced glucose utilization: insights from humans and transgenic animals.

Journal: Biochemical Society transactions 20030201

Title: Selective suppression of AMP-activated protein kinase in skeletal muscle: update on 'lazy mice'.

Journal: Biochemical Society transactions 20030201

Title: AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase.

Journal: Diabetologia 20030201

Title: Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells.

Journal: The Journal of biological chemistry 20030110

Title: Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase.

Journal: Diabetes 20030101

Title: A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20030101

Title: Putative homologs of SSK22 MAPKK kinase and PBS2 MAPK kinase of Saccharomyces cerevisiae encoded by os-4 and os-5 genes for osmotic sensitivity and fungicide resistance in Neurospora crassa.

Journal: Bioscience, biotechnology, and biochemistry 20030101

Title: 5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells.

Journal: Neuroscience 20030101

Title: A new approach for syntheses of 2',3'-dideoxy-2',3'-dehydronucleosides using 2,2-difluoro-1,3-dimethylimidazolidine (DFI) as a dehydrating reagent.

Journal: Nucleosides, nucleotides & nucleic acids 20030101

Title: At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation.

Journal: Journal of biology 20030101

Title: AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20021201

Title: ATP depletion increases phosphorylation of elongation factor eEF2 in adult cardiomyocytes independently of inhibition of mTOR signalling.

Journal: FEBS letters 20021120

Title: Protein kinase inhibitors block the stimulation of the AMP-activated protein kinase by 5-amino-4-imidazolecarboxamide riboside.

Journal: FEBS letters 20021106

Title: AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20021101

Title: Intermittent increases in cytosolic Ca2+ stimulate mitochondrial biogenesis in muscle cells.

Journal: American journal of physiology. Endocrinology and metabolism 20021101

Title: AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat.

Journal: American journal of physiology. Endocrinology and metabolism 20021101

Title: Hemodynamic actions of acute ethanol after resuscitation from traumatic brain injury.

Journal: The Journal of trauma 20021101

Title: AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats.

Journal: Diabetes 20021001

Title: Effects of iprodione and fludioxonil on glycerol synthesis and hyphal development in Candida albicans.

Journal: Bioscience, biotechnology, and biochemistry 20021001

Title: The cryptic adenine deaminase gene of Escherichia coli. Silencing by the nucleoid-associated DNA-binding protein, H-NS, and activation by insertion elements.

Journal: The Journal of biological chemistry 20020830

Title: Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells.

Journal: FEBS letters 20020828

Title: Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis.

Journal: Current biology : CB 20020820

Title: Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle.

Journal: Biochemical and biophysical research communications 20020816

Title: Regulation of the forkhead transcription factor FKHR (FOXO1a) by glucose starvation and AICAR, an activator of AMP-activated protein kinase.

Journal: Endocrinology 20020801

Title: Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes.

Journal: European journal of biochemistry 20020801

Title: Application of (13)C-filtered (1)H NMR to evaluate drug action on gluconeogenesis and glycogenolysis simultaneously in isolated rat hepatocytes.

Journal: NMR in biomedicine 20020801

Title: AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling.

Journal: The Journal of biological chemistry 20020705

Title: Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome.

Journal: Diabetes 20020701

Title: Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes.

Journal: Current drug targets. Immune, endocrine and metabolic disorders 20020701

Title: Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport.

Journal: The Journal of biological chemistry 20020628

Title: Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations.

Journal: Biochemical and biophysical research communications 20020621

Title: Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20020607

Title: Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20020601

Title: Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20020601

Title: Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK).

Journal: Journal of cell science 20020601

Title: The fixM flavoprotein modulates inhibition by AICAR or 5'AMP of respiratory and nitrogen fixation gene expression in Sinorhizobium meliloti.

Journal: Molecular plant-microbe interactions : MPMI 20020601

Title: AMP-activated protein kinase kinase: detection with recombinant AMPK alpha1 subunit.

Journal: Biochemical and biophysical research communications 20020510

Title: Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca(2+).

Journal: American journal of physiology. Endocrinology and metabolism 20020501

Title: A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes.

Journal: Developmental biology 20020501

Title: Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply.

Journal: Endocrinology 20020401

Title: Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells.

Journal: The Biochemical journal 20020401

Title: Down-regulation of Lsm1 is involved in human prostate cancer progression.

Journal: British journal of cancer 20020318

Title: An mRNA splice variant of the AFX gene with altered transcriptional activity.

Journal: The Journal of biological chemistry 20020308

Title: Molecular dissection of alleles of the osmotic-1 locus of Neurospora crassa.

Journal: Fungal genetics and biology : FG & B 20020301

Title: Effect of AICAR treatment on glycogen metabolism in skeletal muscle.

Journal: Diabetes 20020301

Title: Regulation of phosphatidylcholine and phosphatidylethanolamine synthesis in rat hepatocytes by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

Journal: The Biochemical journal 20020215

Title: Mechanism for fatty acid 'sparing' effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase.

Journal: The Journal of biological chemistry 20020208

Title: Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle.

Journal: Diabetes 20020201

Title: 5-amino-4-imidazolecarboxamide riboside confers strong tolerance to glucose starvation in a 5'-AMP-activated protein kinase-dependent fashion.

Journal: Biochemical and biophysical research communications 20020111

Title: Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation.

Journal: Diabetes 20020101

Title: 5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.

Journal: Diabetologia 20020101

Title: 5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside.

Journal: The Journal of biological chemistry 20011214

Title: 5-aminoimidazole-4-carboxy-amide-1-beta-D-ribofuranoside treatment ameliorates hyperglycaemia and hyperinsulinaemia but not dyslipidaemia in KKAy-CETP mice.

Journal: Diabetologia 20011201

Title: Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase.

Journal: The Journal of biological chemistry 20011102

Title: AMP-activated protein kinase activation prevents denervation-induced decline in gastrocnemius GLUT-4.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20011101

Title: Penetration of dacarbazine and its active metabolite 5-aminoimidazole-4-carboxamide into cutaneous metastases of human malignant melanoma.

Journal: Cancer 20011015

Title: Role of AMP-activated protein kinase in mechanism of metformin action.

Journal: The Journal of clinical investigation 20011015

Title: Regulation of myocardial fatty acid oxidation by substrate supply.

Journal: American journal of physiology. Heart and circulatory physiology 20011001

Title: Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line.

Journal: Biochemical and biophysical research communications 20010921

Title: A facile synthesis of [N1,NH(2-)(15)N(2)], [N3,NH(2-)(15)N(2)] and [N2, N3,NH(2-)(15)N(3)]-labeled adenine.

Journal: The Journal of organic chemistry 20010921

Title: The effects of AICAR on adipocyte differentiation of 3T3-L1 cells.

Journal: Biochemical and biophysical research communications 20010907

Title: Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20010901

Title: Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010901

Title: Stir bar sorptive extraction applied to the determination of dicarboximide fungicides in wine.

Journal: Journal of chromatography. A 20010831

Title: Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR.

Journal: American journal of physiology. Endocrinology and metabolism 20010801

Title: AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.

Journal: Journal of molecular neuroscience : MN 20010801

Title: Calculation of relative binding free energy differences for fructose 1,6-bisphosphatase inhibitors using the thermodynamic cycle perturbation approach.

Journal: Journal of the American Chemical Society 20010704

Title: Hepatocyte nuclear factor-4alpha involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase.

Journal: Diabetes 20010701

Title: Activation of acetyl-CoA carboxylase by a glutamate- and magnesium-sensitive protein phosphatase in the islet beta-cell.

Journal: Diabetes 20010701

Title: Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells.

Journal: Circulation research 20010622

Title: Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway.

Journal: The Journal of biological chemistry 20010601

Title: Combination therapy that targets secondary pulmonary changes after abdominal trauma.

Journal: Shock (Augusta, Ga.) 20010601

Title: Evaluation of the catalytic mechanism of AICAR transformylase by pH-dependent kinetics, mutagenesis, and quantum chemical calculations.

Journal: Journal of the American Chemical Society 20010523

Title: Determination of dichloroanilines in human urine by GC-MS, GC-MS-MS, and GC-ECD as markers of low-level pesticide exposure.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20010501

Title: Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

Journal: Diabetes 20010501

Title: Characterization of mutations in the two-component histidine kinase gene that confer fludioxonil resistance and osmotic sensitivity in the os-1 mutants of Neurospora crassa.

Journal: Pest management science 20010501

Title: Insulin and contraction directly stimulate UCP2 and UCP3 mRNA expression in rat skeletal muscle in vitro.

Journal: Biochemical and biophysical research communications 20010427

Title: Stimulation of IGF-binding protein-1 secretion by AMP-activated protein kinase.

Journal: Biochemical and biophysical research communications 20010420

Title: Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK.

Journal: The Biochemical journal 20010415

Title: Acute exposure to AICAR increases glucose transport in mouse EDL and soleus muscle.

Journal: Biochemical and biophysical research communications 20010413

Title: A purine-related metabolite negatively regulates fixNOQP expression in Sinorhizobium meliloti by modulation of fixK expression.

Journal: Molecular plant-microbe interactions : MPMI 20010401

Title: Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity.

Journal: The Journal of biological chemistry 20010316

Title: The protective effect of acadesine on lung ischemia-reperfusion injury.

Journal: Anesthesia and analgesia 20010301

Title: The AMP-activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytes.

Journal: FEBS letters 20010202

Title: Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner.

Journal: Diabetes 20010101

Title: Nitrogen-dependent accumulation of cytokinins in root and the translocation to leaf: implication of cytokinin species that induces gene expression of maize response regulator.

Journal: Plant & cell physiology 20010101

Title: Isonucleosides incorporating universal bases.

Journal: Nucleosides, nucleotides & nucleic acids 20010101

Title: Effect of 5-aminoimidazole-4-carboxamide riboside (AICA-r) on isolated thoracic aorta responses in streptozotocin-diabetic rats.

Journal: Journal of basic and clinical physiology and pharmacology 20010101

Title: Effect of some compounds on the decay of strawberry fruits caused by Botrytis cinerea Pers.

Journal: Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20010101

Title: Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency.

Journal: Human molecular genetics 20000901

Title: Evidence for the direct transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase.

Journal: Biochemistry 19990309

Title: Acadesine: a unique cardioprotective agent for myocardial ischemia.

Journal: Heart disease (Hagerstown, Md.) 19990101

Title: AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle.

Journal: The American journal of physiology 19971201

Title: Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.

Journal: Biochemical pharmacology 19951109

Title: Acadesine: a new drug that may improve myocardial protection in coronary artery bypass grafting. Results of the first international multicenter study. Multinational Acadesine Study Group.

Journal: The Journal of thoracic and cardiovascular surgery 19951001

Title: Degradation of iprodione by a soil Arthrobacter-like strain.

Journal: Applied and environmental microbiology 19950901

Title: 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

Journal: European journal of biochemistry 19950415

Title: Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.

Journal: Biochemistry 19941004

Title: N5-carboxyaminoimidazole ribonucleotide: evidence for a new intermediate and two new enzymatic activities in the de novo purine biosynthetic pathway of Escherichia coli.

Journal: Biochemistry 19940301

Title: Acadesine (AICA-riboside): disposition and metabolism of an adenosine-regulating agent.

Journal: Journal of clinical pharmacology 19931001

Title: Detection of 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole in urine by use of the Bratton-Marshall reaction: identification of patients deficient in adenylosuccinate lyase activity.

Journal: Analytical biochemistry 19860701

Title: An infantile autistic syndrome characterised by the presence of succinylpurines in body fluids.

Journal: Lancet (London, England) 19841110

Title: Disruption of AMPKalpha1 signaling prevents AICAR-induced inhibition of AS160/TBC1D4 phosphorylation and glucose uptake in primary rat adipocytes.

Journal: Molecular endocrinology (Baltimore, Md.)

Title: YANG LIU. VARIABLE-TEMPERATURE 1 H-NMR AND AB INITIO STUDY OF 5-AMINO-IMIDAZOLE-4-CARBOXAMIDE (AICA): COMPETING PATHS FOR AMIDE-H SCRAMBLING. DECEMBER 2008.

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Tags:360-97-4 Molecular Formula|360-97-4 MDL|360-97-4 SMILES|360-97-4 4-Amino-5-imidazolecarboxamide |Heterocyclic_Building_Blocks