Title: Benzyl isothiocyanate attenuates the hydrogen peroxide-induced interleukin-13 expression through glutathione S-transferase P induction in T lymphocytic leukemia cells.
Journal: Journal of biochemical and molecular toxicology20180601
Title: Benzyl isothiocyanate ameliorates acetaldehyde-induced cytotoxicity by enhancing aldehyde dehydrogenase activity in murine hepatoma Hepa1c1c7 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20171001
Title: Development and application of a method for identification of isothiocyanate-targeted molecules in colon cancer cells.
Journal: Analytical biochemistry20121015
Title: Hepatoma-derived growth factor regulates breast cancer cell invasion by modulating epithelial--mesenchymal transition.
Journal: The Journal of pathology20121001
Title: Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migration.
Journal: Breast cancer research and treatment20120801
Title: Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120801
Title: Identifying and characterizing binding sites on the irreversible inhibition of human glutathione S-transferase P1-1 by S-thiocarbamoylation.
Journal: Chembiochem : a European journal of chemical biology20120723
Title: Enhancement of cisplatin cytotoxicity by benzyl isothiocyanate in HL-60 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120701
Title: Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae.
Journal: Pest management science20120501
Title: Molecular and life-history effects of a natural toxin on herbivorous and non-target soil arthropods.
Journal: Ecotoxicology (London, England)20120501
Title: First study on antimicriobial activity and synergy between isothiocyanates and antibiotics against selected Gram-negative and Gram-positive pathogenic bacteria from clinical and animal source.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20120501
Title: Optimized labeling of NOTA-conjugated octreotide with F-18.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine20120401
Title: Content determination of benzyl glucosinolate and anti-cancer activity of its hydrolysis product in Carica papaya L.
Journal: Asian Pacific journal of tropical medicine20120301
Title: 3-Benzyl-6-methyl-2-sulfanylidene-2,3-di-hydroquinazolin-4(1H)-one.
Journal: Acta crystallographica. Section E, Structure reports online20120301
Title: Cytotoxicity of benzyl isothiocyanate in normal renal proximal tubular cells and its modulation by glutathione.
Journal: Journal of agricultural and food chemistry20120222
Title: Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
Journal: Journal of agricultural and food chemistry20120118
Title: Varied response of Spodoptera littoralis against Arabidopsis thaliana with metabolically engineered glucosinolate profiles.
Journal: Plant physiology and biochemistry : PPB20120101
Title: Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells.
Journal: Molecular and cellular biochemistry20120101
Title: The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.
Journal: Journal of oncology20120101
Title: Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3).
Journal: BMC medicine20120101
Title: α-Tocopherol sensitizes human leukemia HL-60 cells to apoptosis induced by benzyl isothiocyanate.
Journal: Bioscience, biotechnology, and biochemistry20120101
Title: Dual-wavelength imaging of tumor progression by activatable and targeting near-infrared fluorescent probes in a bioluminescent breast cancer model.
Journal: PloS one20120101
Title: Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell death.
Journal: PloS one20120101
Title: Herbivory by a Phloem-feeding insect inhibits floral volatile production.
Journal: PloS one20120101
Title: Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells.
Journal: PloS one20120101
Title: Antimicrobial activities of isothiocyanates against Campylobacter jejuni isolates.
Journal: Frontiers in cellular and infection microbiology20120101
Title: Nanoemulsions of cancer chemopreventive agent benzyl isothiocyanate display enhanced solubility, dissolution, and permeability.
Journal: Journal of agricultural and food chemistry20111214
Title: Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
Journal: The British journal of nutrition20111201
Title: Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis.
Journal: International journal of molecular medicine20111201
Title: Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors.
Journal: Amino acids20111101
Title: Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice.
Journal: Breast cancer research and treatment20111101
Title: Characteristics of papaya seed oils obtained by extrusion-expelling processes.
Journal: Journal of the science of food and agriculture20111001
Title: Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin.
Journal: Molecular nutrition & food research20111001
Title: Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.
Journal: The Journal of biological chemistry20110923
Title: Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity.
Journal: Journal of molecular biology20110909
Title: Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society20110801
Title: Assessment of the protective effects of selected dietary anticarcinogens against DNA damage and cytogenetic effects induced by benzo[a]pyrene in C57BL/6J mice.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20110801
Title: Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates.
Journal: Bioorganic & medicinal chemistry letters20110801
Title: In vitro and in vivo antifungal activity of synthetic pure isothiocyanates against Sclerotinia sclerotiorum.
Journal: Pest management science20110701
Title: Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells.
Journal: Cancer prevention research (Philadelphia, Pa.)20110701
Title: The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics.
Journal: Chemico-biological interactions20110630
Title: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways.
Journal: Human & experimental toxicology20110401
Title: Structural requirements for mutation formation from polycyclic aromatic hydrocarbon dihydrodiol epoxides in their interaction with food chemopreventive compounds.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20110401
Title: Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20110401
Title: Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways.
Journal: Cell death & disease20110401
Title: Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.
Journal: Carcinogenesis20110301
Title: The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
Journal: International journal of oncology20110301
Title: Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships.
Journal: Journal of medicinal chemistry20110210
Title: Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.
Journal: Carcinogenesis20110201
Title: MicroRNA-375 and MicroRNA-221: Potential Noncoding RNAs Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer.
Journal: Genes & cancer20110201
Title: Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile--identification of novel compounds.
Journal: Talanta20110115
Title: Dietary phenethyl isothiocyanate alters gene expression in human breast cancer cells.
Journal: Evidence-based complementary and alternative medicine : eCAM20110101
Title: Medicinal plants used as antitumor agents in Brazil: an ethnobotanical approach.
Journal: Evidence-based complementary and alternative medicine : eCAM20110101
Title: Role of mitochondrial electron transport chain complexes in capsaicin mediated oxidative stress leading to apoptosis in pancreatic cancer cells.
Journal: PloS one20110101
Title: Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells.
Journal: PloS one20110101
Title: Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera.
Journal: Nutrition and cancer20110101
Title: Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria.
Journal: PloS one20110101
Title: Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice.
Journal: Breast cancer research : BCR20110101
Title: Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors.
Journal: PloS one20110101
Title: Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.
Journal: PloS one20110101
Title: Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration.
Journal: PloS one20110101
Title: Antiplasmodial Properties and Bioassay-Guided Fractionation of Ethyl Acetate Extracts from Carica papaya Leaves.
Journal: Journal of parasitology research20110101
Title: Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.
Journal: Clinical epigenetics20110101
Title: Glutathione s-transferases in pediatric cancer.
Journal: Frontiers in oncology20110101
Title: Phytochemical and antifungal profiles of the seeds of carica papaya L.
Journal: Indian journal of pharmaceutical sciences20110101
Title: Determination of new biomarkers to monitor the dietary consumption of isothiocyanates.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals20101201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters20101101
Title: Analogues of morphanthridine and the tear gas dibenz[b,f][1,4]oxazepine (CR) as extremely potent activators of the human transient receptor potential ankyrin 1 (TRPA1) channel.
Journal: Journal of medicinal chemistry20101014
Title: Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetala, and their main individual constituents.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20101001
Title: Evaluation of antibacterial activity of 3-butenyl, 4-pentenyl, 2-phenylethyl, and benzyl isothiocyanate in Brassica vegetables.
Journal: Journal of food science20100901
Title: Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells.
Journal: The Journal of nutrition20100801
Title: Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Journal: Journal of medicinal chemistry20100722
Title: Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.
Journal: Molecular cancer therapeutics20100601
Title: p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression.
Journal: Cancer prevention research (Philadelphia, Pa.)20100601
Title: Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate.
Journal: Molecular carcinogenesis20100501
Title: Antimicrobial activity of phenolics and glucosinolate hydrolysis products and their synergy with streptomycin against pathogenic bacteria.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20100501
Title: New biomarkers for monitoring the levels of isothiocyanates in humans.
Journal: Chemical research in toxicology20100419
Title: Enhanced Nrf2-dependent induction of glutathione in mouse embryonic fibroblasts by isoselenocyanate analog of sulforaphane.
Journal: Bioorganic & medicinal chemistry letters20100415
Title: Phytochemicals in cancer prevention and therapy: truth or dare?
Journal: Toxins20100401
Title: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Journal: Journal of agricultural and food chemistry20100310
Title: Chloroplastic phosphoadenosine phosphosulfate metabolism regulates basal levels of the prohormone jasmonic acid in Arabidopsis leaves.
Journal: Plant physiology20100301
Title: The toxic effects of benzyl glucosinolate and its hydrolysis product, the biofumigant benzyl isothiocyanate, to Folsomia fimetaria.
Journal: Environmental toxicology and chemistry20100201
Title: Immunochemical detection of food-derived isothiocyanate as a lysine conjugate.
Journal: Bioscience, biotechnology, and biochemistry20100101
Title: Cruciferous vegetable intake is inversely associated with lung cancer risk among smokers: a case-control study.
Journal: BMC cancer20100101
Title: Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells.
Journal: BMC cancer20100101
Title: Molecular and cellular designs of insect taste receptor system.
Journal: Frontiers in cellular neuroscience20100101
Title: Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.
Journal: Journal of molecular signaling20100101
Title: Ethnopharmacological survey among migrants living in the Southeast Atlantic Forest of Diadema, São Paulo, Brazil.
Journal: Journal of ethnobiology and ethnomedicine20100101
Title: Salvadora persica.
Journal: Pharmacognosy reviews20100101
Title: Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate.
Journal: Cancer research20091215
Title: Benzyl isothiocyanate exhibits anti-inflammatory effects in murine macrophages and in mouse skin.
Journal: Journal of molecular medicine (Berlin, Germany)20091201
Title: [Antimicrobial efficacy of benzyl isothiocyanate].
Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan20091201
Title: Benzyl isothiocyanate inhibits murine WEHI-3 leukemia cells in vitro and promotes phagocytosis in BALB/c mice in vivo.
Journal: Leukemia research20091101
Title: A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.
Journal: Biochemistry20091020
Title: Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery.
Journal: Biochemical and biophysical research communications20091016
Title: Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.
Journal: Carcinogenesis20091001
Title: Growth-inhibiting activities of phenethyl isothiocyanate and its derivatives against intestinal bacteria.
Journal: Journal of food science20091001
Title: Anti-proliferative and proapoptotic effects of benzyl isothiocyanate on human pancreatic cancer cells is linked to death receptor activation and RasGAP/Rac1 down-modulation.
Journal: International journal of oncology20090901
Title: Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region.
Journal: Toxicology20090630
Title: Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes.
Journal: The Journal of biological chemistry20090619
Title: Re: The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
Journal: Journal of the National Cancer Institute20090616
Title: Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.
Journal: Toxicology and applied pharmacology20090615
Title: Degradation and sorption of 2-propenyl and benzyl isothiocyanate in soil.
Journal: Environmental toxicology and chemistry20090601
Title: Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20090601
Title: The antimicrobial effects of glucosinolates and their respective enzymatic hydrolysis products on bacteria isolated from the human intestinal tract.
Journal: Journal of applied microbiology20090601
Title: Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation therapy.
Journal: Frontiers in bioscience (Elite edition)20090601
Title: Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells.
Journal: British journal of cancer20090505
Title: Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily.
Journal: Journal of experimental botany20090301
Title: The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
Journal: Journal of the National Cancer Institute20090204
Title: Aurintricarboxylic acid inhibits influenza virus neuraminidase.
Journal: Antiviral research20090201
Title: Isothiocyanates repress estrogen receptor alpha expression in breast cancer cells.
Journal: Oncology reports20090101
Title: Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L.
Journal: Foodborne pathogens and disease20090101
Title: Phytochemical induction of cell cycle arrest by glutathione oxidation and reversal by N-acetylcysteine in human colon carcinoma cells.
Journal: Nutrition and cancer20090101
Title: Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells.
Journal: Cancer cell international20090101
Title: Differing mechanisms of simple nitrile formation on glucosinolate degradation in Lepidium sativum and Nasturtium officinale seeds.
Journal: Phytochemistry20090101
Title: (-)-Epigallocatechin-3-gallate potentiates the cytotoxicity induced by benzyl isothiocyanate and hydrogen peroxide in human Jurkat T lymphocytes.
Journal: Bioscience, biotechnology, and biochemistry20081101
Title: Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine.
Journal: Journal of clinical biochemistry and nutrition20081101
Title: Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.
Journal: The Journal of biological chemistry20081031
Title: Benzylglucosinolate, benzylisothiocyanate, and myrosinase activity in papaya fruit during development and ripening.
Journal: Journal of agricultural and food chemistry20081022
Title: Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles.
Journal: Proceedings of the National Academy of Sciences of the United States of America20081014
Title: ATP depletion alters the mode of cell death induced by benzyl isothiocyanate.
Journal: Biochimica et biophysica acta20081001
Title: Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation.
Journal: International journal of oncology20081001
Title: Cancer is a preventable disease that requires major lifestyle changes.
Journal: Pharmaceutical research20080901
Title: Suppressive Effects of Selected Food Phytochemicals on CD74 Expression in NCI-N87 Gastric Carcinoma Cells.
Journal: Journal of clinical biochemistry and nutrition20080901
Title: Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20080701
Title: Herbal compounds and toxins modulating TRP channels.
Journal: Current neuropharmacology20080301
Title: Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.
Journal: PloS one20080101
Title: Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate.
Journal: PloS one20080101
Title: Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis.
Journal: BMC cancer20080101
Title: Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.
Journal: Nutrition and cancer20080101
Title: Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
Journal: Bioscience, biotechnology, and biochemistry20071001
Title: Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents.
Journal: Biological chemistry20071001
Title: Formation and degradation kinetics of the biofumigant benzyl isothiocyanate in soil.
Journal: Environmental science & technology20070615
Title: Papaya seed represents a rich source of biologically active isothiocyanate.
Journal: Journal of agricultural and food chemistry20070530
Title: Selective cytotoxicity of benzyl isothiocyanate in the proliferating fibroblastoid cells.
Journal: International journal of cancer20070201
Title: Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis.
Journal: Breast cancer research : BCR20070101
Title: Comments regarding: Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro Kalkunte S, Swamy N, Dizon DS, Brard L. J Exp Ther Oncol.5(4):287-300, 2006.
Journal: Journal of experimental therapeutics & oncology20070101
Title: p38MAPK mediates benzyl isothiocyanate-induced p21WAF1 expression in vascular smooth muscle cells via the regulation of Sp1.
Journal: Biochemical and biophysical research communications20061124
Title: Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak.
Journal: Molecular cancer therapeutics20061101
Title: Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.
Journal: Cancer letters20060928
Title: Characterization of two Arabidopsis thaliana glutathione S-transferases.
Journal: Plant cell reports20060901
Title: Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.
Journal: Biochemical pharmacology20060714
Title: Haplotype-environment interactions that regulate the human glutathione S-transferase P1 promoter.
Journal: Cancer research20060615
Title: Raphanus sativus and its isothiocyanates inhibit vascular smooth muscle cells proliferation and induce G(1) cell cycle arrest.
Journal: International immunopharmacology20060501
Title: Invasive plant suppresses the growth of native tree seedlings by disrupting belowground mutualisms.
Journal: PLoS biology20060501
Title: Effects of benzyl and phenethyl isothiocyanate on P450s 2A6 and 2A13: potential for chemoprevention in smokers.
Journal: Carcinogenesis20060401
Title: Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells.
Journal: Journal of agricultural and food chemistry20060308
Title: The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.
Journal: Anti-cancer drugs20060301
Title: Cell death induction by isothiocyanates and their underlying molecular mechanisms.
Journal: BioFactors (Oxford, England)20060101
Title: Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro.
Journal: Journal of experimental therapeutics & oncology20060101
Title: Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction.
Journal: Bioscience, biotechnology, and biochemistry20051201
Title: Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Journal: Current drug metabolism20051001
Title: The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20050901
Title: Modulation of jejunal contractions by extract of Carica papaya L. seeds.
Journal: Phytotherapy research : PTR20050701
Title: A novel function of benzyl isothiocyanate in vascular smooth muscle cells: the role of ERK1/2, cell cycle regulation, and matrix metalloproteinase-9.
Journal: Journal of cellular physiology20050601
Title: The identification of 1,3-oxazolidine-2-thiones and 1,3-thiazolidine-2-thiones from the reaction of glucose with benzyl isothiocyanate.
Journal: Carbohydrate research20050207
Title: Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site.
Journal: The Journal of biological chemistry20041126
Title: Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye.
Journal: The Journal of biological chemistry20041119
Title: Targeting of a head and neck squamous cell carcinoma xenograft model using the chimeric monoclonal antibody U36 radioiodinated with a closo-dodecaborate-containing linker.
Journal: Acta oto-laryngologica20041101
Title: Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli.
Journal: Bioscience, biotechnology, and biochemistry20041101
Title: Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20041001
Title: Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20041001
Title: Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.
Journal: Carcinogenesis20040901
Title: Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines.
Journal: Experimental biology and medicine (Maywood, N.J.)20040901
Title: Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20040801
Title: Effects of benzyl-, phenethyl-, and alpha-naphthyl isothiocyanates on P-glycoprotein- and MRP1-mediated transport.
Journal: Journal of pharmaceutical sciences20040701
Title: Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro.
Journal: Drug metabolism and disposition: the biological fate of chemicals20040601
Title: Effect of benzyl isothiocyanate on spontaneous and induced force of rat uterine contraction.
Journal: Pharmacological research20040501
Title: Pregnancy outcomes following pre- and post-implantation exposure of Sprague-Dawley rats to benzyl isothiocyanate.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20040501
Title: Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis.
Journal: Carcinogenesis20040401
Title: A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.
Journal: Cancer research20040315
Title: In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20040301
Title: Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
Journal: Environmental and molecular mutagenesis20040101
Title: Benzyl isothiocyanate modifies expression of the G2/M arrest-related genes.
Journal: BioFactors (Oxford, England)20040101
Title: Benzyl isothiocyanate inhibits oxidative stress in mouse skin: Involvement of attenuation of leukocyte infiltration.
Journal: BioFactors (Oxford, England)20040101
Title: Tocolytic and toxic activity of papaya seed extract on isolated rat uterus.
Journal: Life sciences20031219
Title: Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.
Journal: Cancer science20031101
Title: Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma.
Journal: Carcinogenesis20031001
Title: Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats.
Journal: The British journal of nutrition20030801
Title: Naturally occurring Phe151Leu substitution near a conserved folding module lowers stability of glutathione transferase P1-1.
Journal: Biochimica et biophysica acta20030626
Title: Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages.
Journal: Cancer letters20030530
Title: Determination of amino acids in foods by reversed-phase HPLC with new precolumn derivatives, butylthiocarbamyl, and benzylthiocarbamyl derivatives compared to the phenylthiocarbamyl derivative and ion exchange chromatography.
Journal: Molecular biotechnology20030501
Title: Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats.
Journal: Carcinogenesis20030301
Title: Effects of garden and water cress juices and their constituents, benzyl and phenethyl isothiocyanates, towards benzo(a)pyrene-induced DNA damage: a model study with the single cell gel electrophoresis/Hep G2 assay.
Journal: Chemico-biological interactions20030106
Title: Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
Journal: Nutrition and cancer20030101
Title: Involvement of toxicity as an early event in urinary bladder carcinogenesis induced by phenethyl isothiocyanate, benzyl isothiocyanate, and analogues in F344 rats.
Journal: Toxicologic pathology20030101
Title: Benzyl isothiocyanate: an effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung.
Journal: Cancer letters20021210
Title: Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine.
Journal: Pharmaceutical research20021001
Title: Investigation of the tuber constituents of maca (Lepidium meyenii Walp.).
Journal: Journal of agricultural and food chemistry20020925
Title: Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
Journal: Carcinogenesis20020901
Title: Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions.
Journal: Carcinogenesis20020701
Title: Effects of papaya seed extract and benzyl isothiocyanate on vascular contraction.
Journal: Life sciences20020621
Title: Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages.
Journal: Life sciences20020614
Title: Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis.
Journal: The Journal of biological chemistry20020308
Title: Palladium(0)-catalyzed enantioselective O,S-rearrangement of racemic O-allylic thiocarbamates: a new entry to enantioenriched allylic sulfur compounds.
Journal: The Journal of organic chemistry20020222
Title: Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
Journal: Cancer research20020101
Title: Pyridazine derivatives and related compounds, part 9. tetrazolo[1,5-b]pyridazine-8-carbohydrazide: synthesis and some reactions.
Journal: Bollettino chimico farmaceutico20020101
Title: Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Journal: Nutrition and cancer20020101
Title: 4-(Methylthio)-3-butenyl isothiocyanate, a principal antimutagen in daikon (Raphanus sativus; Japanese white radish).
Journal: Journal of agricultural and food chemistry20011201
Title: Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes.
Journal: Chemical research in toxicology20010901
Title: Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.
Journal: Cancer research20010815
Title: Differential effects of naturally occurring isothiocyanates on the activities of cytochrome P450 2E1 and the mutant P450 2E1 T303A.
Journal: Archives of biochemistry and biophysics20010701
Title: Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts.
Journal: Phytochemistry20010601
Title: Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
Journal: The Journal of pharmacology and experimental therapeutics20010101
Title: Toxic effects of benzyl and allyl isothiocyanates and benzyl-isoform specific metabolites in the urinary bladder after a single intravesical application to rats.
Journal: Toxicologic pathology20010101
Title: Increased bioactivation of dihaloalkanes in rat liver due to induction of class theta glutathione S-transferase T1-1.
Journal: The Biochemical journal19981101
Title: Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity.
Journal: Cancer research19980201
Title: Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE).
Journal: Molecular medicine (Cambridge, Mass.)19951101
Title: Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases.
Journal: Biochemical and biophysical research communications19950117
Title: Abdel-Kader MS, et al. Quantitative Analysis of Benzyl Isothiocyanate in Salvadora persica Extract and Dental Care Herbal Formulations Using Reversed Phase C18 High-Performance Liquid Chromatography Method. Pharmacogn Mag. 2017 Oct;13(Suppl 3):S412-S416.
Title: Lai KC, et al. Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. Int J Oncol. 2017 Sep;51(3):832-840.
